Joseph Linton Roberts
Professor Emeritus of Pediatrics

My overall research interests are studying T cell development and defining the molecular bases of inherited immunodeficiency diseases. We are using standard candidate gene analysis approaches as well as new high throughput genome-wide sequencing, bioinformatics and functional screening in zebrafish and murine models in our work. Using these strategies we have recently reported a new molecular etiology of severe combined immunodeficiency (SCID), CD3 zeta chain deficiency. In collaboration with Dr. Wesley Burks we are also examining changes in T cell transcription patterns following treatment for peanut allergy using genome wide oligonucleotide microarrays.

Current Appointments & Affiliations

Contact Information

  • Box 2898 Med Ctr, Durham, NC 27710
  • Room 101B Msrb1, Duke University Medical Center, Durham, NC 27710

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