Scholars@Duke
Robert Walker Benjamin

Robert Walker Benjamin

Professor of Pediatrics
Pediatrics, Endocrinology
robert.benjamin@duke.edu
Box 102820, Durham, NC 27710
3000 Erwin Road, Durham, NC 27710

Selected Publications

Insulin for Treatment of Neonatal Hyperglycemia in Premature Infants: Prevalence over Time and Association with Outcomes.

Journal Article Am J Perinatol · May 2024 OBJECTIVE: Our objective was to determine the prevalence of insulin treatment in premature infants with hyperglycemia and evaluate the association of length of treatment with outcomes. STUDY DESIGN: The study included cohort of 29,974 infants 22 to 32 week ... Full text Link to item Cite

Innovations: Using telemedicine to improve care of predominantly non-white youth with suboptimal insulin dependent diabetes control.

Journal Article Diabetes Res Clin Pract · April 2024 AIM: Despite advances in diabetes treatments, youth commonly fail to meet glucose targets. Telehealth support may help youth meet diabetes related goals. The objective of the project was to assess whether intensive telehealth support in a group of poorly c ... Full text Link to item Cite

Catabolism of fats and branched-chain amino acids in children with Type 1 diabetes: Association with glycaemic control and total daily insulin dose.

Journal Article Endocrinol Diabetes Metab · November 2023 OBJECTIVE: Hyperglycaemia in Type 1 diabetes (T1D) results from an absolute insulin deficiency. However, insulin resistance (IR) may exacerbate glycaemic instability in T1D and contribute to long-term cardiovascular complications. We previously showed that ... Full text Link to item Cite

Development of hepatocellular adenomas in a patient with glycogen storage disease Ia treated with growth hormone therapy.

Journal Article JIMD Rep · September 2023 Glycogen storage disease Ia (GSD Ia), also known as von Gierke disease, is caused by pathogenic variants in the G6PC1 gene (OMIM 232200) which encodes glucose-6-phosphatase. Deficiency of glucose-6-phosphatase impairs the processes of gluconeogenesis and g ... Full text Link to item Cite

Disrupted Pediatric Diabetes Trends in the Second Year of the COVID-19 Pandemic

Journal Article Journal of the Endocrine Society · August 1, 2023 Context: Increases in incident cases of pediatric type 1 (T1D) and type 2 diabetes (T2D) were observed during the first year of the COVID-19 pandemic. Objective: This work aimed to identify trends in incidence and presentation of pediatric new-onset T1D an ... Full text Cite

Pediatric disorders of stature

Chapter · January 1, 2023 Assessment of a child's weight and linear growth can be the first clue to an underlying medical problem and should be a critical component of each visit to the pediatrician. Several factors influence growth, including maternal-fetal health during pregnancy ... Full text Cite

Pediatric Diabetes on the Rise: Trends in Incident Diabetes During the COVID-19 Pandemic.

Journal Article J Endocr Soc · April 1, 2022 CONTEXT: The effects of the coronavirus disease 2019 (COVID-19) pandemic on the incident cases of pediatric type 1 diabetes (T1D) and type 2 diabetes (T2D) are not clear. OBJECTIVE: To identify trends in incidence and presentation of pediatric new-onset T1 ... Full text Link to item Cite

Case Report: Infant With Congenital Adrenal Hyperplasia and 47,XXY.

Journal Article Front Genet · 2021 Congenital adrenal hyperplasia is a group of autosomal recessive disorders in which enzymes in the cortisol biosynthesis pathways are disrupted by gene mutations. The most common form of congenital adrenal hyperplasia, caused by 21-hydroxylase deficiency, ... Full text Link to item Cite

Role of continuous glucose monitoring in the management of glycogen storage disorders.

Journal Article J Inherit Metab Dis · November 2018 Management of liver glycogen storage diseases (GSDs) primarily involves maintaining normoglycemia through dietary modifications and regular glucose monitoring. Self-monitoring of blood glucose is typically done 3-6 times per day, and may not sufficiently c ... Full text Link to item Cite

Prevalence and safety of diazoxide in the neonatal intensive care unit.

Journal Article J Perinatol · November 2018 OBJECTIVE: Diazoxide is used to treat infants with persistent hypoglycemia, but the prevalence of its use and adverse effects are not well described. We report demographic and clinical characteristics of infants treated with diazoxide in neonatal intensive ... Full text Link to item Cite

A Tablet-Based Educational Tool: Toward More Comprehensive Pediatric Patient Education.

Journal Article Clin Pediatr (Phila) · September 2018 There is a paucity of data on the impact of mobile technology on physician-led education in the pediatric population. We performed a prospective pilot study in a pediatric diabetes clinic to evaluate the impact of tablet-based patient education. A total of ... Full text Link to item Cite

Effect of the Adoption of a Comprehensive Electronic Health Record on Graduate Medical Education: Perceptions of Faculty and Trainees.

Journal Article South Med J · August 2018 OBJECTIVES: Health systems are adopting electronic health records (EHRs). There are few studies on the effects of EHR implementation on graduate medical education. The authors sought to longitudinally assess perceptions of the impact of EHRs on graduate me ... Full text Link to item Cite

Developing Teaching Strategies in the EHR Era: A Survey of GME Experts.

Journal Article J Grad Med Educ · October 2016 BACKGROUND: There is limited information on the impact of widespread adoption of the electronic health record (EHR) on graduate medical education (GME). OBJECTIVE: To identify areas of consensus by education experts, where the use of EHR impacts GME, with ... Full text Link to item Cite

Can Tablet Computers Enhance Faculty Teaching?

Journal Article J Grad Med Educ · June 2015 BACKGROUND: Learner benefits of tablet computer use have been demonstrated, yet there is little evidence regarding faculty tablet use for teaching. OBJECTIVE: Our study sought to determine if supplying faculty with tablet computers and peer mentoring provi ... Full text Link to item Cite

Hypercalcemia in children.

Journal Article Pediatr Endocrinol Rev · March 2008 Hypercalcemia is an occasional clinical problem in outpatient and in patient pediatrics. If undiagnosed and untreated, it can cause significant sequelae. While the differential diagnosis of hypercalcemia is expansive, the clinician can isolate the cause wi ... Link to item Cite

A non-transformed oligodendrocyte precursor cell line, OL-1, facilitates studies of insulin-like growth factor-I signaling during oligodendrocyte development.

Journal Article Int J Dev Neurosci · April 2007 The process by which oligodendrocyte progenitors differentiate into mature oligodendrocytes is complex and incompletely understood in part because of the paucity of oligodendrocyte precursors cell lines that can be studied in culture. We have developed a n ... Full text Link to item Cite

Hyperthyroidism and lupus-like syndrome in an adolescent treated with minocycline for acne vulgaris.

Journal Article Pediatr Dermatol · 2007 Minocycline is a tetracycline antibiotic commonly used in the treatment of acne. While it is generally considered to be a safe medicine, a number of side effects have been associated with its use. We describe an adolescent boy who developed hyperthyroidism ... Full text Link to item Cite