Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Member of Duke Molecular Physiology Institute
·
2017 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Design and rationale of the pERSonalized cardIovascuLar dIsease prEvention, treatmeNt, and CarE (RESILIENCE) study.
Journal Article Contemp Clin Trials · June 4, 2026 BACKGROUND: Obesity is a growing epidemic associated with cardiovascular disease (CVD). The RESILIENCE study aimed to understand the factors underlying heterogeneity in CVD development among individuals with obesity as well as the variability in response t ... Full text Link to item CiteMetabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction.
Journal Article Circ Heart Fail · November 2024 BACKGROUND: Mechanisms of benefit with SGLT2is (sodium-glucose cotransporter-2 inhibitors) in heart failure (HF) remain incompletely characterized. Dapagliflozin alters ketone and fatty acid metabolism in HF with reduced ejection fraction though similar ef ... Full text Link to item CiteMitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes.
Journal Article JCI Insight · September 8, 2023 Metabolic mechanisms underlying the heterogeneity of major adverse cardiovascular (CV) event (MACE) risk in individuals with type 2 diabetes mellitus (T2D) remain unclear. We hypothesized that circulating metabolites reflecting mitochondrial dysfunction pr ... Full text Link to item CiteRecent Grants
MK-0616
Clinical TrialCo Investigator · Awarded by Merck Sharp & Dohme LLC. · 2024 - 2030Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029Stimulating Access to Research in Residency (StARR) - NHLBI
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028View All Grants
Education
University of North Carolina, Chapel Hill, School of Medicine ·
2008
M.D.