Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Cardiology,
Medicine
Member of Duke Molecular Physiology Institute
·
2017 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Metabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction.
Journal Article Circ Heart Fail · November 2024 BACKGROUND: Mechanisms of benefit with SGLT2is (sodium-glucose cotransporter-2 inhibitors) in heart failure (HF) remain incompletely characterized. Dapagliflozin alters ketone and fatty acid metabolism in HF with reduced ejection fraction though similar ef ... Full text Link to item CiteMitochondrial metabolites predict adverse cardiovascular events in individuals with diabetes.
Journal Article JCI Insight · September 8, 2023 Metabolic mechanisms underlying the heterogeneity of major adverse cardiovascular (CV) event (MACE) risk in individuals with type 2 diabetes mellitus (T2D) remain unclear. We hypothesized that circulating metabolites reflecting mitochondrial dysfunction pr ... Full text Link to item CiteSerum Metabolites Are Associated With HFpEF in Biopsy-Proven Nonalcoholic Fatty Liver Disease.
Journal Article J Am Heart Assoc · July 18, 2023 Background Nonalcoholic fatty liver disease (NAFLD) and heart failure with preserved ejection fraction (HFpEF) share common risk factors, including obesity and diabetes. They are also thought to be mechanistically linked. The aim of this study was to defin ... Full text Link to item CiteRecent Grants
MK-0616
Clinical TrialCo Investigator · Awarded by Merck Sharp & Dohme LLC. · 2024 - 2030Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029Stimulating Access to Research in Residency (StARR) - NHLBI
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill, School of Medicine ·
2008
M.D.