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Rohit Singh

Assistant Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics

Overview


Rohit Singh is an Assistant Professor in the Departments of Biostatistics & Bioinformatics and Cell Biology at Duke Univ. His research interests are broadly in computational biology, with a focus on using machine learning to make drug discovery more efficient. Currently, he's exploring how single-cell genomics and large language models can help decode disease mechanisms and aid in identifying new targets and drugs. He is the recipient of the Test of Time Award at RECOMB, MIT's George M. Sprowls Award for his PhD thesis in Computer Science, and Stanford's Christopher Stephenson Memorial Award for Masters Research in the same field. In addition to academia, he has experience in the industry.

Current Appointments & Affiliations


Assistant Professor of Biostatistics & Bioinformatics · 2023 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Assistant Professor of Cell Biology · 2023 - Present Cell Biology, Basic Science Departments
Assistant Professor in the Department of Electrical and Computer Engineering · 2023 - Present Electrical and Computer Engineering, Pratt School of Engineering
Assistant Professor of Computer Science · 2024 - Present Computer Science, Trinity College of Arts & Sciences

Recent Publications


Topology-driven discovery of transmembrane protein S-palmitoylation.

Journal Article J Biol Chem · March 2025 Protein S-palmitoylation is a reversible lipophilic posttranslational modification regulating diverse signaling pathways. Within transmembrane proteins (TMPs), S-palmitoylation is implicated in conditions from inflammatory disorders to respiratory viral in ... Full text Link to item Cite
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Recent Grants


Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

Revealing the hidden topologies of the human kinome

ResearchCollaborator · Awarded by Chan Zuckerberg Initiative · 2023 - 2026

Revealing the Molecular Architecture of PWS Through Large Language Models for Targeted Drug Purposing

ResearchPrincipal Investigator · Awarded by Foundation for Prader-Willi Research · 2024 - 2026

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Education, Training & Certifications


Massachusetts Institute of Technology · 2012 Ph.D.