Journal ArticleThe Journal of biological chemistry · May 1995
The membrane topology of the skeletal muscle ryanodine receptor (RyR1) was investigated using site-directed antibodies directed against amino acid sequences 2804-2930, 4581-4640, 4860-4886, and 4941-5037. Ab(2804-2930) bound with identical affinity to eith ...
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Journal ArticleBiochimica et biophysica acta · September 1990
The binding of the carboxylic ionophore lasalocid A (X537A) to small unilamellar phospholipid vesicles of varying composition was examined in an effort to determine what structural features of the phospholipid membrane influence the ionophore-membrane inte ...
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Journal ArticleMolecular pharmacology · May 1988
The interaction of the bacterial dihydrofolate reductase inhibitor trimethoprim with small unilamellar 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine vesicles was studied using 13C and 31P NMR spectroscopy. In an effort to determine whether trimethoprim pa ...
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Journal ArticleBiochimica et biophysica acta · July 1986
The spectral and metabolic properties of Rhodamine 123, a fluorescent cationic dye used to label mitochondria in living cells, were investigated in suspensions of isolated rat-liver mitochondria. A red shift of Rhodamine 123 absorbance and fluorescence occ ...
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Journal ArticleThe Journal of biological chemistry · March 1984
From measurements of reactants, products, and the oxidation-reduction state of cytochrome c + c1 during 3-hydroxybutyrate-supported oxidative phosphorylation by rat liver mitochondria at static head (state 4), we determined the free energy change of ATP fo ...
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Journal ArticleProceedings of the National Academy of Sciences of the United States of America · April 1982
Two distinct thyrotropin (TSH) binding species have been separated from solubilized porcine thyroid membranes. Membranes was solubilized with 1% Triton X-100, and the supernatant was recovered by centrifugation at 105,000 X g. Scatchard analysis of thyrotr ...
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