Ross A. Widenhoefer | Scholars@Duke

Ross A. Widenhoefer
Professor of Chemistry

Research in the Widenhoefer group is directed toward the development and mechanistic analysis of new organotransition metal-catalyzed transformations for application in the synthesis of functionalized organic molecules. In particular, our group has a long-standing interest in the functionalization of C–C multiple bonds with carbon and heteroatom nucleophiles catalyzed by electrophilic late transition metal complexes, with a recent focus on the synthetic and mechanistic aspect of gold(I) pi-activation catalysis. Current areas of inquiry include the following: 1) Gold(I) and Pt(II)-catalyzed hydroamination of alkenes an allenes. 2) Gold(I)-catalyzed dehydrative amination of underivatized allylic alcohols. 3) Synthesis and study of cationic, two-coordinate gold pi-complexes. 4) Evaluating the role of bis(gold) complexes in gold pi-activation catalysis. More detailed descriptions of these research projects can be found at our group web page.

Current Appointments & Affiliations

Professor of Chemistry, Chemistry, Trinity College of Arts & Sciences 2007
Director of Undergraduate Studies of Chemistry, Chemistry, Trinity College of Arts & Sciences 2018

Contact Information

124 Science Drive, 2101 French Science Center, Durham, NC 27708
Box 90346, Durham, NC 27708-0346
ross.widenhoefer@duke.edu (919) 660-1533
Widenhoefer Research Group

Background
Education, Training, & Certifications
- Ph.D., University of Wisconsin at Madison 1994
- B.A., Gustavus Adolphus College 1989
Duke Appointment History
- Associate Professor of Chemistry, Chemistry, Trinity College of Arts & Sciences 2003 - 2007
- Assistant Professor of Chemistry, Chemistry, Trinity College of Arts & Sciences 1997 - 2003
Recognition
Awards & Honors
- Sloan Research Fellowship-Chemistry. Alfred P. Sloan Foundation. 2000
Research
Selected Grants
- Reactive Intermediates in Gold(I) Catalysis awarded by National Science Foundation 2015 - 2021
- Multi-State Catalysts Modulated by Mechanical Force awarded by Department of Energy 2017 - 2019
- Hydrogenolysis of C(sp3)-O Bonds Catalyzed by Acidic Group 9 Hydride Complexes awarded by American Chemical Society 2016 - 2019
- MRI: Acquisition of a Triple Quadrupole LC/MS System awarded by National Science Foundation 2015 - 2018
- Synthesis and study of potential intermediates in gold(I) pi-activation catalysis" awarded by National Science Foundation 2012 - 2015
- Fluxional Mechanocatalysis awarded by U.S. Army Research, Development & Engineering Command 2011 - 2014
- MRI: Acquisition of An Accu-TOF DART Mass Spectrometer awarded by National Science Foundation 2009 - 2012
- Synthesis and Study of Cationic Gold (I) Alkene and Allene Complexes awarded by National Science Foundation 2009 - 2012
- Catalytic Hydrofunctionalization as a Route to Heterocyclic Compounds awarded by National Institutes of Health 2007 - 2011
- Purchase of a Q-TOF LC/MS System awarded by National Institutes of Health 2010 - 2011
- Catalytic Addition of Nucleophiles to Unactivated Olefins awarded by National Science Foundation 2006 - 2010
- Harnessing Macroscopic Forces in Catalysis awarded by Army Research Office 2008 - 2009
- Palladium-Catalyzed Alkylation of Unactivated Olefins awarded by National Science Foundation 2003 - 2006
- Palladium Catalyzed Cyclization of Functionalized Dienes awarded by National Institutes of Health 1999 - 2004
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Harris, RJ, Carden, RG, Duncan, AN, and Widenhoefer, RA. "Kinetics and Mechanism of the Gold-Catalyzed Intermolecular Hydroalkoxylation of Allenes with Alcohols." Acs Catalysis 8, no. 9 (September 7, 2018): 8941-8952. Full Text
  - Kim, N, and Widenhoefer, RA. "Synthesis, Characterization, and Reactivity of Cationic Gold Diarylallenylidene Complexes." Angewandte Chemie (International Ed. in English) 57, no. 17 (April 2018): 4722-4726. Full Text
  - Carden, RG, Lam, N, and Widenhoefer, RA. "Experimental Evaluation of (L)Au Electron-Donor Ability in Cationic Gold Carbene Complexes." Chemistry (Weinheim an der Bergstrasse, Germany) 23, no. 71 (December 2017): 17992-18001. Full Text
  - Lanier, ML, Park, H, Mukherjee, P, Timmerman, JC, Ribeiro, AA, Widenhoefer, RA, and Hong, J. "Formal Synthesis of (+)-Laurencin by Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation." Chemistry (Weinheim an der Bergstrasse, Germany) 23, no. 30 (May 2017): 7180-7184. Full Text
  - Timmerman, JC, Laulhe, S, and Widenhoefer, RA. "Gold(I)-Catalyzed Intramolecular Hydroamination of Unactivated Terminal and Internal Alkenes with 2-Pyridones." ORGANIC LETTERS 19, no. 6 (March 17, 2017): 1466-1469. Full Text Link to Item
  - Timmerman, JC, Laulhé, S, and Widenhoefer, RA. "Gold(I)-Catalyzed Intramolecular Hydroamination of Unactivated Terminal and Internal Alkenes with 2-Pyridones." Organic Letters 19, no. 6 (March 7, 2017): 1466-1469. Full Text
  - Kim, N, Brooner, REM, and Widenhoefer, RA. "Unexpected Skeletal Rearrangement in the Gold(I)/Silver(I)-Catalyzed Conversion of 7-Aryl-1,6-enynes to Bicyclo[3.2.0]hept-6-enes via Hidden Brønsted Acid Catalysis." Organometallics 36, no. 3 (February 13, 2017): 673-678. Full Text
  - Timmerman, JC, Schmitt, WW, and Widenhoefer, RA. "Gold-Catalyzed Intermolecular, anti-Markovnikov Hydroarylation of Methylenecyclopropanes with Indoles." Organic letters 18, no. 19 (October 2016): 4966-4969. Full Text
  - Harris, RJ, and Widenhoefer, RA. "Gold carbenes, gold-stabilized carbocations, and cationic intermediates relevant to gold-catalysed enyne cycloaddition." Chemical Society Reviews 45, no. 16 (August 2016): 4533-4551. Full Text
  - Li, H, Harris, RJ, Nakafuku, K, and Widenhoefer, RA. "Kinetics and Mechanism of Allene Racemization Catalyzed by a Gold N-Heterocyclic Carbene Complex." Organometallics 35, no. 13 (July 11, 2016): 2242-2248. Full Text
  - Brooner, REM, Brown, TJ, Chee, MA, and Widenhoefer, RA. "Effect of Substitution, Ring Size, and Counterion on the Intermediates Generated in the Gold-Catalyzed Intramolecular Hydroalkoxylation of Allenes." Organometallics 35, no. 11 (June 13, 2016): 2014-2021. Full Text
  - Bender, CF, Brown, TJ, and Widenhoefer, RA. "Mechanism of the Platinum(II)-Catalyzed Hydroamination of 4-Pentenylamines." Organometallics 35, no. 2 (January 25, 2016): 113-125. Full Text
  - Timmerman, JC, and Widenhoefer, RA. "Gold-Catalyzed Intermolecular anti-Markovnikov Hydroamination of Methylenecyclopropanes with 2-Pyridones." Advanced Synthesis and Catalysis 357, no. 16-17 (November 16, 2015): 3703-3706. (Review) Full Text
  - Harris, RJ, and Widenhoefer, RA. "Synthesis and Characterization of a Gold Vinylidene Complex Lacking π-Conjugated Heteroatoms." Angewandte Chemie (International Ed. in English) 54, no. 23 (June 2015): 6867-6869. Full Text
  - Robertson, BD, Brooner, REM, and Widenhoefer, RA. "Tandem gold/silver-catalyzed cycloaddition/hydroarylation of 7-aryl-1,6-enynes to form 6,6-diarylbicyclo[3.2.0]heptanes." Chemistry - A European Journal 21, no. 15 (April 7, 2015): 5714-5717. Full Text
  - Robertson, BD, Brooner, REM, and Widenhoefer, RA. "Tandem gold/silver-catalyzed cycloaddition/hydroarylation of 7-aryl-1,6-enynes to form 6,6-diarylbicyclo[3.2.0]heptanes." Chemistry (Weinheim an der Bergstrasse, Germany) 21, no. 15 (April 2015): 5714-5717. Full Text
  - Timmerman, JC, Robertson, BD, and Widenhoefer, RA. "Gold-catalyzed intermolecular anti-markovnikov hydroamination of alkylidenecyclopropanes." Angewandte Chemie (International ed. in English) 54, no. 7 (February 2015): 2251-2254. Full Text
  - Harris, RJ, and Widenhoefer, RA. "Synthesis and characterization of a gold vinylidene complex lacking π-conjugated heteroatoms." Angewandte Chemie - International Edition 54, no. 23 (2015): 6867-6869. Full Text
  - Kean, ZS, Akbulatov, S, Tian, Y, Widenhoefer, RA, Boulatov, R, and Craig, SL. "Photomechanical actuation of ligand geometry in enantioselective catalysis." Angewandte Chemie (International Ed. in English) 53, no. 52 (December 2014): 14508-14511. Full Text
  - Brooner, REM, Robertson, BD, and Widenhoefer, RA. "Mechanism of 1,3-hydrogen migration in a gold bicyclo[3.2.0]heptene complex: The role of brønsted acid in the gold-catalyzed cycloisomerization of 7-aryl-1,6-enynes." Organometallics 33, no. 22 (November 24, 2014): 6466-6473. Full Text
  - Lee, SD, Timmerman, JC, and Widenhoefer, RA. "Enantioselective intramolecular hydroamination of unactivated alkenes catalyzed by mono- and bis(gold) phosphine complexes." Advanced Synthesis and Catalysis 356, no. 14-15 (October 1, 2014): 3187-3192. Full Text
  - Harris, RJ, Nakafuku, K, and Widenhoefer, RA. "Kinetics and mechanism of the racemization of aryl allenes catalyzed by cationic gold(I) phosphine complexes." Chemistry (Weinheim an der Bergstrasse, Germany) 20, no. 38 (September 2014): 12245-12254. Full Text
  - Lee, SD, Timmerman, JC, and Widenhoefer, RA. "Enantioselective intramolecular hydroamination of unactivated alkenes catalyzed by mono- and bis(gold) phosphine complexes(Accepted)." Advanced Synthesis and Catalysis 342, no. 8 (August 25, 2014). Full Text
  - Harris, RJ, and Widenhoefer, RA. "Synthesis, structure, and reactivity of a gold carbenoid complex that lacks heteroatom stabilization." Angewandte Chemie (International ed. in English) 53, no. 35 (August 2014): 9369-9371. Full Text
  - Brown, TJ, Robertson, BD, and Widenhoefer, RA. "Synthesis and X-ray crystal structure of a cationic gold (I) π-(1,3-diene) complex generated via isomerization of a gold π-allene complex." Journal of Organometallic Chemistry 758 (May 15, 2014): 25-28. Full Text
  - Brown, TJ, Robertson, BD, and Widenhoefer, RA. "Synthesis and X-ray crystal structure of a cationic gold (I) π-(1,3-diene) complex generated via isomerization of a gold π-allene complex." Journal of Organometallic Chemistry 758 (May 2014): 25-28. Full Text
  - Brooner, REM, and Widenhoefer, RA. "Experimental evaluation of the electron donor ability of a gold phosphine fragment in a gold carbene complex." Chem Commun (Camb) 50, no. 19 (March 7, 2014): 2420-2423. Full Text Link to Item
  - Brooner, REM, and Widenhoefer, RA. "Cationic, two-coordinate gold π complexes." Angewandte Chemie (International Ed. in English) 52, no. 45 (November 2013): 11714-11724. Full Text
  - Brooner, REM, Brown, TJ, and Widenhoefer, RA. "Synthesis and study of cationic, two-coordinate triphenylphosphine-gold-π complexes." Chemistry 19, no. 25 (June 17, 2013): 8276-8284. Full Text Link to Item
  - Brooner, REM, Brown, TJ, and Widenhoefer, RA. "Direct observation of a cationic gold(I)-bicyclo[3.2.0]hept-1(7)-ene complex generated in the cycloisomerization of a 7-phenyl-1,6-enyne." Angew Chem Int Ed Engl 52, no. 24 (June 10, 2013): 6259-6261. Full Text Link to Item
  - Mukherjee, P, and Widenhoefer, RA. "The regio- and stereospecific intermolecular dehydrative alkoxylation of allylic alcohols catalyzed by a gold(I) N-heterocyclic carbene complex." Chemistry 19, no. 10 (March 4, 2013): 3437-3444. Full Text Link to Item
  - Brown, TJ, Weber, D, Gagné, MR, and Widenhoefer, RA. "Mechanistic analysis of gold(I)-catalyzed intramolecular allene hydroalkoxylation reveals an off-cycle bis(gold) vinyl species and reversible C-O bond formation." J Am Chem Soc 134, no. 22 (June 6, 2012): 9134-9137. Full Text Link to Item
  - Brown, TJ, Sugie, A, Leed, MGD, and Widenhoefer, RA. "Structures and dynamic solution behavior of cationic, two-coordinate gold(I)-π-allene complexes." Chemistry 18, no. 22 (May 29, 2012): 6959-6971. Full Text Link to Item
  - Butler, KL, Tragni, M, and Widenhoefer, RA. "Gold(I)-catalyzed stereoconvergent, intermolecular enantioselective hydroamination of allenes." Angew Chem Int Ed Engl 51, no. 21 (May 21, 2012): 5175-5178. Full Text Link to Item
  - Brooner, REM, and Widenhoefer, RA. "Erratum: Syntheses, X-ray crystal structures, and solution behavior of cationic, two-coordinate gold(I) η 2-diene complexes (Organometallics (2011))." Organometallics 31, no. 8 (April 23, 2012): 3456-null. Full Text
  - Mukherjee, P, and Widenhoefer, RA. "Gold(I)-catalyzed enantioselective intramolecular dehydrative amination of allylic alcohols with carbamates." Angew Chem Int Ed Engl 51, no. 6 (February 6, 2012): 1405-1407. Full Text Link to Item
  - Brooner, REM, and Widenhoefer, RA. "Synthesis and structure of dicationic, bis(gold) φ-alkene complexes containing a 2,2-bis(phosphino)biphenyl ligand." Organometallics 31, no. 2 (January 23, 2012): 768-771. Full Text
  - Brown, TJ, and Widenhoefer, RA. "Cationic gold(I) π-complexes of terminal alkynes and their conversion to dinuclear σ,π-acetylide complexes." Organometallics 30, no. 21 (November 14, 2011): 6003-6009. Full Text
  - Brooner, REM, and Widenhoefer, RA. "Stereochemistry and mechanism of the Brønsted acid catalyzed intramolecular hydrofunctionalization of an unactivated cyclic alkene." Chemistry 17, no. 22 (May 23, 2011): 6170-6178. Full Text Link to Item
  - Li, H, Song, F, and Widenhoefer, RA. "Gold(I)-Catalyzed Intramolecular Hydroamination of N-Allylic,N'-Aryl Ureas to form Imidazolidin-2-ones." Adv Synth Catal 353, no. 6 (April 18, 2011): 955-962. Full Text Link to Item
  - Mukherjee, P, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular amination of allylic alcohols with alkylamines." Org Lett 13, no. 6 (March 18, 2011): 1334-1337. Full Text Link to Item
  - Brown, TJ, and Widenhoefer, RA. "Synthesis and equilibrium binding studies of cationic, two-coordinate gold(I) π-alkyne complexes." Journal of Organometallic Chemistry 696, no. 6 (March 2011). Full Text
  - Brooner, REM, and Widenhoefer, RA. "Syntheses, x-ray crystal structures, and solution behavior of cationic, two-coordinate gold(I) η²-diene complexes." Organometallics 30, no. 11 (2011): 3182-3193. Full Text
  - Li, H, Lee, SD, and Widenhoefer, RA. "Gold(I)-Catalyzed Enantioselective Intramolecular Hydroamination of Allenes with Ureas." J Organomet Chem 696, no. 1 (January 1, 2011): 316-320. Full Text Link to Item
  - "Gold-Catalyzed Addition of Oxygen Nucleophiles to C-C Multiple Bonds." (October 11, 2010): 462-492. (Chapter) Full Text
  - Brown, TJ, Sugie, A, Dickens, MG, and Widenhoefer, RA. "Solid-state and dynamic solution behavior of a cationic, two-coordinate gold(I) π-allene complex." Organometallics 29, no. 19 (October 11, 2010): 4207-4209. Full Text Open Access Copy
  - Widenhoefer, RA, and Song, F. "Gold-Catalyzed Addition of Nitrogen and Sulfur Nucleophiles to C-C Multiple Bonds." (October 11, 2010): 437-461. (Chapter) Full Text
  - Li, H, and Widenhoefer, RA. "Intramolecular Diamination and Alkoxyamination of Alkenes with N-Sulfonyl Ureas With N-Iodosuccinimide." Tetrahedron 66, no. 26 (June 2010): 4827-4831. Full Text
  - Toups, KL, and Widenhoefer, RA. "Platinum(II)-catalyzed intermolecular hydroamination of monosubstituted allenes with secondary alkylamines." Chem Commun (Camb) 46, no. 10 (March 14, 2010): 1712-1714. Full Text Open Access Copy Link to Item
  - Mukherjee, P, and Widenhoefer, RA. "Gold(I)-catalyzed amination of allylic alcohols with cyclic ureas and related nucleophiles." Organic Letters 12, no. 6 (March 2010): 1184-1187. Full Text Open Access Copy
  - Duncan, AN, and Widenhoefer, RA. "Gold(I)-Catalyzed Intermolecular Hydroamination of Allenes with Arylamines." Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2010, no. 3 (February 2010): 419-422. Full Text
  - Brown, TJ, Dickens, MG, and Widenhoefer, RA. "Syntheses and X-ray crystal structures of cationic, two-coordinate gold(I) pi-alkene complexes that contain a sterically hindered o-biphenylphosphine ligand." Chemical Communications (Cambridge, England) , no. 42 (November 2009): 6451-6453. Full Text
  - Widenhoefer, RA. "Unactivated Alkenes." (September 16, 2009): 203-222. (Chapter) Full Text
  - Li, H, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular dihydroamination of allenes with N,N'-disubstituted ureas to form bicyclic imidazolidin-2-ones." Org Lett 11, no. 12 (June 18, 2009): 2671-2674. Full Text Link to Item
  - Brown, TJ, Dickens, MG, and Widenhoefer, RA. "Syntheses, X-ray crystal structures, and solution behavior of monomeric, cationic, two-coordinate gold(I) pi-alkene complexes." J Am Chem Soc 131, no. 18 (May 13, 2009): 6350-6351. Full Text Link to Item
  - Brown, TJ, Dickens, MG, and Widenhoefer, RA. "Syntheses, x-ray crystal structures, and solution behavior of monomeric, cationic, two-coordinate gold(I) π-alkene complexes." Journal of the American Chemical Society 131, no. 18 (May 13, 2009): 6350-6351. Full Text
  - Zhang, Z, Lee, SD, and Widenhoefer, RA. "Intermolecular hydroamination of ethylene and 1-alkenes with cyclic ureas catalyzed by achiral and chiral gold(I) complexes." J Am Chem Soc 131, no. 15 (April 22, 2009): 5372-5373. Full Text Link to Item
  - Zhang, Z, Du Lee, S, Fisher, AS, and Widenhoefer, RA. "Gold(I)-Catalyzed Hydration of Allenes." Tetrahedron 65, no. 9 (February 28, 2009): 1794-1798. Full Text Link to Item
  - Toups, KL, Liu, GT, and Widenhoefer, RA. "Gold(I)-Catalyzed Hydroarylation of Allenes with Indoles." J Organomet Chem 694, no. 4 (February 15, 2009): 571-575. Full Text Link to Item
  - Toups, KL, Liu, GT, and Widenhoefer, RA. "(I)-Catalyzed Hydroarylation of Allenes with 1,2-Dimethylindole." Organomet. Chem. , no. 694 (2009): 571-575. (Academic Article)
  - Widenhoefer, RA. "A palladium-catalyzed formal (4+1) annulation: a new approach to cyclopentene construction." Angewandte Chemie (International Ed. in English) 48, no. 38 (January 2009): 6950-6952. Full Text
  - Kinder, RE, Zhang, Z, and Widenhoefer, RA. "Intermolecular hydroamination of allenes with N-unsubstituted carbamates catalyzed by a gold(I) N-heterocyclic carbene complex." Organic Letters 10, no. 14 (July 2008): 3157-3159. Full Text
  - Bender, CF, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular hydroamination of unactivated C==C bonds with alkyl ammonium salts." Chem Commun (Camb) , no. 24 (June 28, 2008): 2741-2743. Full Text Link to Item
  - Widenhoefer, RA. "Recent developments in enantioselective gold(I) catalysis." Chemistry a European Journal 14, no. 18 (June 20, 2008): 5382-5391. Full Text
  - Bender, CF, Hudson, WB, and Widenhoefer, RA. "Sterically hindered mono(phosphines) as supporting ligands for the platinum-catalyzed hydroamination of amino alkenes." Organometallics 27, no. 10 (May 26, 2008): 2356-2358. Full Text
  - Zhang, Z, and Widenhoefer, RA. "Regio- and stereoselective synthesis of alkyl allylic ethers via gold(I)-catalyzed intermolecular hydroalkoxylation of allenes with alcohols." Organic Letters 10, no. 10 (May 2008): 2079-2081. Full Text
  - Widenhoefer, RA. "Recent developments in enantioselective gold(I) catalysis." Chemistry 14, no. 18 (2008): 5382-5391. Full Text Link to Item
  - Zhang, Z, Bender, CF, and Widenhoefer, RA. "Gold(I)-catalyzed dynamic kinetic enantioselective intramolecular hydroamination of allenes." J Am Chem Soc 129, no. 46 (November 21, 2007): 14148-14149. Full Text Link to Item
  - Liu, C, Bender, CF, Han, X, and Widenhoefer, RA. "Platinum-catalyzed hydrofunctionalization of unactivated alkenes with carbon, nitrogen and oxygen nucleophiles." Chem Commun (Camb) , no. 35 (September 21, 2007): 3607-3618. Full Text Link to Item
  - Han, X, and Widenhoefer, RA. "Palladium-mediated cyclization of 6-methyl-1-phenyl-6-hepten-2-one to form 3-methyldiphenylmethane: Carbonyl activation by a neutral palladium(II) complex." Organometallics 26, no. 16 (July 30, 2007): 4061-4065. Full Text
  - Zhang, Z, Bender, CF, and Widenhoefer, RA. "Gold(I)-catalyzed enantioselective hydroamination of N-allenyl carbamates." Org Lett 9, no. 15 (July 19, 2007): 2887-2889. Full Text Link to Item
  - Liu, C, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular enantioselective hydroarylation of allenes with indoles." Organic Letters 9, no. 10 (May 2007): 1935-1938. Full Text
  - Zhang, Z, and Widenhoefer, RA. "Gold(I)-Catalyzed Intramolecular Asymmetric Hydroalkoxylation of Allenes." Angew. Chem. , no. 119 (2007): 287-289. (Academic Article)
  - Zhang, Z, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular enantioselective hydroalkoxylation of allenes." Angewandte Chemie International Edition 46, no. 1-2 (January 1, 2007): 283-285. (Academic Article) Full Text Link to Item
  - Zhang, Z, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular enantioselective hydroalkoxylation of allenes." Angew Chem Int Ed Engl 46, no. 1-2 (2007): 283-285. Full Text Link to Item
  - Bender, CF, and Widenhoefer, RA. "Room temperature hydroamination of N-alkenyl ureas catalyzed by a gold(i) N-heterocyclic carbene complex." Org Lett 8, no. 23 (November 9, 2006): 5303-5305. Full Text Link to Item
  - Bender, CF, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular hydroamination of unactivated alkenes with carboxamides." Chem Commun (Camb) , no. 39 (October 21, 2006): 4143-4144. Full Text Link to Item
  - Widenhoefer, RA, and Han, X. "Gold-catalyzed hydroamination of C-C multiple bonds." European Journal of Organic Chemistry , no. 20 (October 13, 2006): 4555-4563. Full Text
  - Zhang, Z, Wang, X, and Widenhoefer, RA. "Platinum(II)-catalyzed intermolecular hydroarylation of unactivated alkenes with indoles." Chem Commun (Camb) , no. 35 (September 21, 2006): 3717-3719. Full Text Link to Item
  - Han, X, and Widenhoefer, RA. "Platinum-catalyzed intramolecular asymmetric hydroarylation of unactivated alkenes with indoles." Organic Letters 8, no. 17 (August 2006): 3801-3804. Full Text
  - Zhang, Z, Liu, C, Kinder, RE, Han, X, Qian, H, and Widenhoefer, RA. "Highly active Au(I) catalyst for the intramolecular exo-hydrofunctionalization of allenes with carbon, nitrogen, and oxygen nucleophiles." J Am Chem Soc 128, no. 28 (July 19, 2006): 9066-9073. Full Text Link to Item
  - Kinder, RE, and Widenhoefer, RA. "Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes." Org Lett 8, no. 10 (May 11, 2006): 1967-1969. Full Text Link to Item
  - Han, X, and Widenhoefer, RA. "Gold(I)-catalyzed intramolecular hydroamination of alkenyl carbamates." Angew Chem Int Ed Engl 45, no. 11 (March 3, 2006): 1747-1749. Full Text Link to Item
  - Liu, C, and Widenhoefer, RA. "Scope and mechanism of the Pd(II)-catalyzed arylation/carboalkoxylation of unactivated olefins with indoles." Chemistry 12, no. 8 (March 1, 2006): 2371-2382. Full Text Link to Item
  - Qian, H, and Widenhoefer, RA. "Platinum-catalyzed intermolecular hydroamination of vinyl arenes with carboxamides." Org Lett 7, no. 13 (June 23, 2005): 2635-2638. Full Text Link to Item
  - Bender, CF, and Widenhoefer, RA. "Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines." Journal of the American Chemical Society 127, no. 4 (February 2005): 1070-1071. Full Text
  - Qian, H, Pei, T, and Widenhoefer, RA. "Development, scope, and mechanism of the palladium-catalyzed intramolecular hydroalkylation of 3-butenyl β-diketones." Organometallics 24, no. 2 (January 17, 2005): 287-301. Full Text
  - Liu, C, and Widenhoefer, RA. "Platinum(II)/europium(III)-catalyzed intramolecular hydroalkylation of 4-pentenyl β-dicarbonyl compounds." Tetrahedron Letters 46, no. 2 (January 10, 2005): 285-287. Full Text
  - Han, X, Wang, X, Pei, T, and Widenhoefer, RA. "Palladium-catalyzed intramolecular hydroalkylation of alkenyl-beta-keto esters, alpha-aryl ketones, and alkyl ketones in the presence of Me3SiCl or HCl." Chemistry 10, no. 24 (December 3, 2004): 6333-6342. Full Text Link to Item
  - Liu, C, Wang, X, Pei, T, and Widenhoefer, RA. "Palladium-catalyzed intramolecular oxidative alkylation of 4-pentenyl beta-dicarbonyl compounds." Chemistry 10, no. 24 (December 3, 2004): 6343-6352. Full Text Link to Item
  - Goj, LA, Cisneros, GA, Yang, W, and Widenhoefer, RA. "Erratum: "Dramatic effect of homoallylic substitution on the rate of palladium-catalyzed diene cycloisomerization" (Journal of Organometallic Chemistry (2003) vol. 687 (498-507) 10.1016/j.jorganchem.2003.09.046)." Journal of Organometallic Chemistry 689, no. 17 (September 1, 2004): 2845-null. Full Text
  - Liu, C, Han, X, Wang, X, and Widenhoefer, RA. "Erratum: Platinum-catalyzed intramolecular alkylation of indoles with unactivated olefins (Journal of the American Chemical Society (2004) 126 (3700-3701))." Journal of the American Chemical Society 126, no. 33 (August 25, 2004): 10493-null.
  - Qian, H, Han, X, and Widenhoefer, RA. "Platinum-catalyzed intramolecular hydroalkoxylation of gamma- and delta-hydroxy olefins to form cyclic ethers." J Am Chem Soc 126, no. 31 (August 11, 2004): 9536-9537. Full Text Link to Item
  - Liu, C, Han, X, Wang, X, and Widenhoefer, RA. "Platinum-Catalyzed Intramolecular Alkylation of Indoles with Unactivated Olefins [J. Am. Chem. Soc.2004,126, 3700−3701]." Journal of the American Chemical Society 126, no. 33 (August 2004): 10493-10493. Full Text
  - Liu, C, and Widenhoefer, RA. "Palladium-catalyzed cyclization/carboalkoxylation of alkenyl indoles." Journal of the American Chemical Society 126, no. 33 (August 2004): 10250-10251. Full Text
  - Perch, NS, and Widenhoefer, RA. "Mechanism of palladium-catalyzed diene cyclization/hydrosilylation: direct observation of intramolecular carbometalation." J Am Chem Soc 126, no. 20 (May 26, 2004): 6332-6346. Full Text Link to Item
  - Wang, X, and Widenhoefer, RA. "Platinum-Catalyzed Intermolecular Hydroamination of Unactivated Olefins with Carboxamides." Organometallics 23, no. 8 (April 12, 2004): 1649-1651. Full Text
  - Wang, X, and Widenhoefer, RA. "Palladium(II)- and platinum(II)-catalyzed addition of stabilized carbon nucleophiles to ethylene and propylene." Chem Commun (Camb) , no. 6 (March 21, 2004): 660-661. Full Text Link to Item
  - Han, X, and Widenhoefer, RA. "Palladium-catalyzed oxidative alkoxylation of alpha-alkenyl beta-diketones to form functionalized furans." J Org Chem 69, no. 5 (March 5, 2004): 1738-1740. Full Text Link to Item
  - Liu, C, Han, X, Wang, X, and Widenhoefer, RA. "Platinum-catalyzed intramolecular alkylation of indoles with unactivated olefins." Journal of the American Chemical Society 126, no. 12 (March 2004): 3700-3701. Full Text
  - Han, X, Wang, X, Pei, T, and Widenhoefer, RA. ""Palladium-Catalyzed Intramolecular Hydroalkylation of Alkenyl - β - Keto Esters, -Aryl Ketones, and Alkyl Ketones in the presence of Me3SiCl or HCI"." Chem. Eur J. 10 (2004): 6332-6342. (Academic Article)
  - Liu, C, and Widenhoefer, RA. "Palladium-Catalyzed Cyclization/Carboalkoxylation of Alkenyl Indoles." J. Am. Chem. Soc. 126 (2004): 10246-10247. (Academic Article)
  - Widenhoefer, RA. "Palladium-catalyzed alkylation of unactivated olefins." Pure and Applied Chemistry 76, no. 3 (January 1, 2004): 671-678. Full Text
  - Goj, LA, Cisneros, GA, Yang, W, and Widenhoefer, RA. "Dramatic effect of homoallylic substitution on the rate of palladium-catalyzed diene cycloisomerization." Journal of Organometallic Chemistry 687, no. 2 (December 7, 2003): 498-507. Full Text
  - Wang, X, Pei, T, Han, X, and Widenhoefer, RA. "Palladium-catalyzed intramolecular hydroalkylation of unactivated olefins with dialkyl ketones." Org Lett 5, no. 15 (July 24, 2003): 2699-2701. Full Text Link to Item
  - Qian, H, and Widenhoefer, RA. "Mechanism of the palladium-catalyzed intramolecular hydroalkylation of 7-octene-2,4-dione." J Am Chem Soc 125, no. 8 (February 26, 2003): 2056-2057. Full Text Link to Item
  - Chakrapani, H, Liu, C, and Widenhoefer, RA. "Enantioselective cyclization/hydrosilylation of 1,6-enynes catalyzed by a cationic rhodium bis(phosphine) complex." Org Lett 5, no. 2 (January 23, 2003): 157-159. Full Text Link to Item
  - Pei, T, Wang, X, and Widenhoefer, RA. "Palladium-catalyzed intramolecular oxidative alkylation of unactivated olefins." J Am Chem Soc 125, no. 3 (January 22, 2003): 648-649. Full Text Link to Item
  - Liu, G, and Widenhoefer, RA. "Cyclization/hydrosilylation of functionalized diynes catalyzed by a cationic rhodium bis(phosphine) complex." Organometallics 21, no. 25 (December 9, 2002): 5666-5673. Full Text
  - Widenhoefer, RA. "Synthetic and mechanistic studies of the cycloisomerization and cyclization/hydrosilylation of functionalized dienes catalyzed by cationic palladium(II) complexes." Acc Chem Res 35, no. 10 (October 2002): 905-913. (Review) Link to Item
  - Wang, X, Chakrapani, H, Madine, JW, Keyerleber, MA, and Widenhoefer, RA. "Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands." J Org Chem 67, no. 9 (May 3, 2002): 2778-2788. Link to Item
  - Pei, T, and Widenhoefer, RA. "Palladium-catalyzed cyclization of alkenyl beta-keto esters in the presence of chlorotrimethylsilane." Chem Commun (Camb) , no. 6 (March 21, 2002): 650-651. Link to Item
  - Wang, X, Stankovich, SZ, and Widenhoefer, RA. "Palladium-catalyzed ring-opening cyclization/hydrosilylation of 1-cyclopropyl-1,6-heptadienes to form (E)-1-butenyl cyclopentanes." Organometallics 21, no. 5 (March 4, 2002): 901-905. Full Text
  - Perch, NS, and Widenhoefer, RA. "Direct observation of the conversion of a palladium 5-hexenyl chelate complex to a palladium cyclopentylmethyl complex." Organometallics 20, no. 25 (December 10, 2001): 5251-5253. Full Text
  - Pei, T, and Widenhoefer, RA. "Palladium-catalyzed asymmetric diene cyclization/hydrosilylation employing functionalized silanes and disiloxanes." J Org Chem 66, no. 23 (November 16, 2001): 7639-7645. Link to Item
  - Goj, LA, and Widenhoefer, RA. "Mechanistic studies of the cycloisomerization of dimethyl diallylmalonate catalyzed by a cationic palladium phenanthroline complex." J Am Chem Soc 123, no. 45 (November 14, 2001): 11133-11147. Link to Item
  - Pei, T, and Widenhoefer, RA. "Palladium-catalyzed intramolecular addition of 1,3-diones to unactivated olefins." J Am Chem Soc 123, no. 45 (November 14, 2001): 11290-11291. Link to Item
  - Wang, X, Chakrapani, H, Stengone, CN, and Widenhoefer, RA. "Synthesis of Carbobicyclic Compounds via Palladium-Catalyzed Cyclization/ Hydrosilylation: Evidence for Reversible Silylpalladation." The Journal of Organic Chemistry 66, no. 23 (November 2001): 7930-7930. Full Text
  - Madine, JW, Wang, X, and Widenhoefer, RA. "Cyclization/Hydrosilylation of Functionalized Diynes Catalyzed by a Cationic Platinum Phenanthroline Complex." Organic Letters 3, no. 10 (May 2001): 1591-1592. Full Text
  - Wang, X, Chakrapani, H, Stengone, CN, and Widenhoefer, RA. "Synthesis of carbobicyclic compounds via palladium-catalyzed cyclization/hydrosilylation: evidence for reversible silylpalladation." J Org Chem 66, no. 5 (March 9, 2001): 1755-1760. Link to Item
  - Madine, JW, Wang, X, and Widenhoefer, RA. "Cyclization/hydrosilylation of functionalized diynes catalyzed by a cationic platinum phenanthroline complex." Org Lett 3, no. 3 (February 8, 2001): 385-388. Link to Item
  - Kisanga, P, Goj, LA, and Widenhoefer, RA. "Cycloisomerization of functionalized 1,5- and 1,6-dienes catalyzed by cationic palladium phenanthroline complexes." J Org Chem 66, no. 2 (January 26, 2001): 635-637. Link to Item
  - Kisanga, P, and Widenhoefer, RA. "Development, synthetic scope, and mechanistic studies of the palladium-catalyzed cycloisomerization of functionalized 1,6-dienes in the presence of silane." Journal of the American Chemical Society 122, no. 41 (October 18, 2000): 10017-10026. Full Text
  - Pei, T, and Widenhoefer, RA. "Asymmetric diene cyclization/hydrosilylation/oxidation employing 1-tert-butyl-3,3-dimethyl-1,1-diphenyldisiloxane." Tetrahedron Letters 41, no. 40 (September 30, 2000): 7597-7600. Full Text
  - Perch, NS, Kisanga, P, and Widenhoefer, RA. "Reductive cyclization of dimethyl diallylmalonate catalyzed by palladium-bisoxazoline complexes in the presence of silane and water." ORGANOMETALLICS 19, no. 13 (June 26, 2000): 2541-2545. Full Text Link to Item
  - Perch, NS, Pei, T, and Widenhoefer, RA. "Enantioselective diene Cyclization/Hydrosilylation catalyzed by optically active palladium bisoxazoline and pyridine-oxazoline complexes." J Org Chem 65, no. 12 (June 16, 2000): 3836-3845. Link to Item
  - Pei, T, and Widenhoefer, RA. "Use of pentamethyldisiloxane in the palladium-catalyzed cyclization/hydrosilylation of functionalized dienes." Org Lett 2, no. 10 (May 18, 2000): 1469-1471. Link to Item
  - Widenhoefer, RA, and Vadehra, A. "An improved catalyst for the cyclization/hydrosilylation of functionalized 1,6-dienes employing dimethylphenylsilane." Tetrahedron Letters 40, no. 49 (December 3, 1999): 8499-8502. Full Text
  - Widenhoefer, RA, and Stengone, CN. "Cyclization/hydrosilylation of functionalized dienes catalyzed by a cationic palladium phenanthroline complex." Journal of Organic Chemistry 64, no. 23 (November 12, 1999): 8681-8692. Full Text
  - Widenhoefer, RA, Vadehra, A, and Cheruvu, PK. "Cyclization/Hydrogermylation of Functionalized 1,6-Dienes Catalyzed by Cationic Palladium Complexes." Organometallics 18, no. 22 (October 25, 1999): 4614-4618. Full Text
  - Perch, NS, and Widenhoefer, RA. "Asymmetric cyclization/hydrosilylation of functionalized 1,6-dienes catalyzed by enantiomerically pure palladium pyridine-oxazoline complexes [13]." Journal of the American Chemical Society 121, no. 29 (July 28, 1999): 6960-6961. (Letter) Full Text
  - Stengone, CN, and Widenhoefer, RA. "Cyclization/hydrosilylation of functionalized 1,7-dienes to form substituted six-membered carbocycles." Tetrahedron Letters 40, no. 8 (February 19, 1999): 1451-1454. Full Text
  - Widenhoefer, RA, and DeCarli, MA. "Tandem Cyclization/Hydrosilylation of Functionalized 1,6-Dienes Catalyzed by a Cationic Palladium Complex." Journal of the American Chemical Society 120, no. 15 (April 1998): 3805-3806. Full Text
  - Widenhoefer, RA, Krzyzanowska, B, and Webb-Wood, G. "Palladium-catalyzed intramolecular hydrosilylation of alkenylsilanes: Selective formation of six-membered silicon heterocycles." Organometallics 17, no. 23 (January 1, 1998): 5124-5127. Full Text
  - Zhong, HA, and Widenhoefer, RA. "Kinetics and Mechanism of the Formation of Palladium Bis(benzylamine) Complexes from Reaction of Benzylamine with Palladium Tri-o-tolylphosphine Mono(amine) Complexes." Inorganic Chemistry 36, no. 12 (December 1, 1997): 2610-2616.
  - Widenhoefer, RA, and Buchwald, SL. "Formation of palladium bis (amine) complexes from reaction of amine with palladium tris(o-tolyl)phosphine mono(amine) complexes." Organometallics 15, no. 16 (August 6, 1996): 3534-3542.
  - Widenhoefer, RA, Zhong, HA, and Buchwald, SL. "Synthesis and solution structure of palladium tris(o-tolyl)phosphine mono(amine) complexes." Organometallics 15, no. 12 (June 11, 1996): 2745-2754.
  - Widenhoefer, RA, and Buchwald, SL. "Halide and amine influence in the equilibrium formation of palladium tris(o-tolyl)phosphine mono(amine) complexes from palladium aryl halide dimers." Organometallics 15, no. 12 (June 11, 1996): 2755-2763.
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reaction of Cp*3Co3(μ3-CCH3)(μ3-H) with (Trimethylsilyl)diazomethane and Ethyl Diazoacetate: Facile Hydrogen Transfer Forms the Diazenide Clusters Cp*3Co3(μ3-CCH3)(μ3-η¹-NNCH2SiMe3)and Cp*3Co3(μ3-CCH3)(μ3-η¹-NNCH2CO2CH2CH3)." Inorganic Chemistry 34, no. 8 (April 1, 1995): 2258-2262. Full Text
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reaction of Cp*3Co3(.mu.3-CCH3)(.mu.3-H) with (Trimethylsilyl)diazomethane and Ethyl Diazoacetate: Facile Hydrogen Transfer Forms the Diazenide Clusters Cp*3Co3(.mu.3-CCH3)(.mu.3-.eta.1-NNCH2SiMe3) and Cp*3Co3(.mu.3-CCH3)(.mu.3-.eta.1-NNCH2CO2Et)." Inorganic Chemistry 34, no. 8 (April 1995): 2258-2262. Full Text
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reactions of Cp*3Co3(μ2-H)3(μ3-H) with Carbon Dioxide, Carbon Disulfide, and Phenyl Isocyanate." Inorganic Chemistry 34, no. 5 (March 1, 1995): 1138-1144. Full Text
  - Casey, CP, Hallenbeck, SL, and Widenhoefer, RA. "Kinetics and Mechanism of the Formation of the Bis(ethylidyne) Tricobalt Cluster Cp*3Co3(μ3-CCH3)2 from Reaction of Acetylene with Cp*3Co3(μ2-H)3(μ3-H)." Journal of the American Chemical Society 117, no. 16 (January 1, 1995): 4607-4622. Full Text
  - Casey, CP, Hallenbeck, SL, and Widenhoefer, RA. "Kinetics and mechanism of the formation of the bis(ethylidyne) tricobalt cluster Cp*₃Co₃(μ₃-CCH₃) ₂ from reaction of acetylene with Cp*₃Co₃(μ₂-H)₃(μ ₃-H)." Journal of the American Chemical Society 117, no. 16 (1995): 4607-4622.
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reaction of Cp*₃Co₃(μ₃-CCH₃)(μ ₃-H) with (Trimethylsilyl)diazomethane and ethyl diazoacetate: Facile hydrogen transfer forms the diazenide clusters Cp*₃Co₃(μ₃-CCH₃)(μ ₃-η¹-NNCH₂SiMe₃) and Cp*₃ .." Inorganic Chemistry 34, no. 8 (1995): 2258-2262.
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reactions of Cp*₃Co₃(μ₂-H)₃(μ ₃-H) with carbon dioxide, carbon bisulfide, and phenyl isocyanate." Inorganic Chemistry 34, no. 5 (1995): 1138-1144.
  - CASEY, CP, WIDENHOEFER, RA, HALLENBECK, SL, HAYASHI, RK, and GAVNEY, JA. "SYNTHESES, X-RAY CRYSTAL-STRUCTURES, AND FLUXIONAL BEHAVIOR OF THE CLUSTERS CP-ASTERISK-CO-3(3)(MU(2)-CO)(MU(3)-CO)(MU-H)(2), CP-ASTERISK-CO-3(3)(MU(2)-H)(MU(3)-ETA(2)-HC=NCME(3)), AND CP-ASTERISK-3CO3(MU(2)-H)(MU(3)-ETA(2)-HC=NCME(2)CH(2)ME)." ORGANOMETALLICS 13, no. 12 (December 1994): 4720-4731. Full Text Link to Item
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, and Gavney, JA. "Syntheses, X-ray Crystal Structures, and Fluxional Behavior of the Clusters Cp*3Co3(μ2-CO)(μ3-CO)(μ-H)2, Cp*3Co3(μ2-H)(μ3-η²-HC=NCMe3), and Cp*3Co3(μ2-H)(μ3-η²-HC=NCMe2CH2Me)." Organometallics 13, no. 12 (December 1, 1994): 4720-4731. Full Text
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, and Hayashi, RK. "Syntheses and X-ray Crystal Structures of the Tricobalt Mono(ethylidyne) Clusters Cp*3Co3(.mu.3-CCH3)(.mu.3-CO)(.mu.2-H), Cp*3Co3(.mu.3-CCH3)(.mu.3-CNCMe3)(.mu.2-H), and Cp*3Co3(.mu.3-CCH3)(.mu.3-NO)." Inorganic Chemistry 33, no. 12 (June 1994): 2639-2644. Full Text
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, and Hayashi, RK. "Syntheses and X-ray Crystal Structures of the Tricobalt Mono(ethylidyne) Clusters Cp*3Co3(µ3-CCH3)(µ3-CO)(µ2-H), Cp*3Co3(µ3-CCH3)(µ3-CNCMe3)(µ2-H), and Cp*3Co3(µ3-CCH3)(µ3-NO)." Inorganic Chemistry 33, no. 12 (June 1, 1994): 2639-2644. Full Text
  - CASEY, CP, WIDENHOEFER, RA, HALLENBECK, SL, HAYASHI, RK, POWELL, DR, and SMITH, GW. "X-RAY CRYSTAL-STRUCTURES OF 2 (ETHYLIDYNE)TRICOBALT CLUSTERS - THERMOLYSIS OF CP-ASTERISK-CO(H2C=CH2)2 PRODUCES CP-ASTERISK-3CO3(MU(3)-CCH3)(MU(3)-H), NOT CP-ASTERISK-3CO3(MU(3)-CCH3)2." ORGANOMETALLICS 13, no. 4 (April 1994): 1521-1524. Full Text Link to Item
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, Powell, DR, and Smith, GW. "X-ray Crystal Structures of Two (Ethylidyne)tricobalt Clusters: Thermolysis of Cp*Co(H2C:CH2)2 Produces Cp*3Co3(.mu.3-CCH3)(.mu.3-H), not Cp*3Co3(.mu.3-CCH3)2." Organometallics 13, no. 4 (April 1994): 1521-1524. Full Text
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, Powell, DR, and Smith, GW. "Xpray Crystal Structures of two Ethylidyne Tricobalt Clusters: Thermolysis of cp*Co(H2C=CH2)2 Froms Cp*3Co3(μ3-CCH3)(μ3-H), not Cp*3Co3(μ3-CCH3)2." Organometallics 13 (1994): 1521-. (Academic Article)
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, Powell, DR, and Smith, GW. "X-ray crystal structures of two (ethylidyne)tricobalt clusters. Thermolysis of Cp*Co(H₂C=CH₂)₂ Produces Cp*₃Co₃(μ₃CCH₃ (μ₃-H), not Cp*₃Co₃(μ₃-CCH₃)₂." Organometallics 13, no. 4 (1994): 1521-1524.
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, and Gavney, JA. "Synthesis, X-ray Crystal Structures and Fluxional Behavior of the Tricobalt Clusters Cp*3C03(μ3-CO)(μ2-CO)(μ-H)2, Cp*3Co3(μ2-H)(μ3-η2-HC=NCMe2CH2Me)." Organometallics 13 (1994): 4720-. (Academic Article)
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, Hayashi, RK, and Gavney, JA. "Syntheses, X-ray crystal structures, and fluxional behavior of the clusters Cp*₃Co₃(μ₂CO)(μ₃-CO)(μ-H)₂, Cp*₃Co₃(μ₂-H) (μ₃-η²-HC=NCMe₃), and Cp*₃Co₃(μ₂-H)." Organometallics 13, no. 12 (1994): 4720-4731.
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, and Hayashi, RK. "Synthesis and X-ray Crystal Structures of the Tricoblat Mono(ethylidyne) Clusters Cp*3Co3(μ3-CCH3)(μ3-CO)(μ2-H), Cp*3Co3(μ3-CCH3)(μ3-CO)(μ2-H), Cp*3Co3(μ3-CCH3)(μ3-CNCMe3)(μ2-H), and Cp*3Co3(μ3-CCH3)(μ3NO)." Inorg. Chem. 33 (1994): 2639-. (Academic Article)
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, and Hayashi, RK. "Syntheses and X-ray crystal structures of the tricobalt mono(ethylidyne) clusters Cp*₃Co₃(μ₃-CCH₃)(μ ₃-CO)(μ₂-H), Cp*₃Co₃(μ₃-CCH₃)(μ ₃-CNCMe₃)(μ₂-H), and Cp*₃Co₃(μ₃-CCH₃)(μ ₃-NO)." Inorganic Chemistry 33, no. 12 (1994): 2639-2644.
  - Casey, CP, Widenhoefer, RA, Hallenbeck, SL, and Gavney, JA. "Reaction of CO and tert-butyl isocyanide with the cluster [(C 5Me5)3Co3(μ2-H) 3(μ3-H)] facile hydrogen transfer to isocyanide forms [(C5Me5)3Co3 (μ-H) (μ3-η²-HC=NCMe3)]." Journal of the Chemical Society, Chemical Communications , no. 22 (December 1, 1993): 1692-1694. Full Text
  - CASEY, CP, WIDENHOEFER, RA, and HAYASHI, RK. "REACTION OF NO WITH CP-ASTERISK-3CO3(MU-H)4 PRESERVES THE TRICOBALT CLUSTER AND PRODUCES CP-ASTERISK-3CO3(MU-3-NO)2." INORGANICA CHIMICA ACTA 212, no. 1-2 (October 1993): 81-85. Full Text Link to Item
  - Casey, C, Widenhoefer, R, Hallenbeck, S, and Gavney, J. "Reaction of CO and tert-Butyl Isocyanide with the Cluster Cp*3Co3(μ2-H)3(μ3-H): Facile Hydrogen Transfer to Isocyanide Forms Cp*3Co3(μ2-H)(μ3-η2-HC=NCMe3)." J. Chem. Soc., Chem. Commun. (1993): 1692-. (Academic Article)
  - Casey, CP, Widenhoefer, RA, and Hallenbeck, SL. "Conversion of Acetylene to a Triple Bridged Ethylidyne Ligand on the Cluster Cp*3Co3(μ2-H)3(μ3-H)." Organometallics 12, no. 10 (January 1, 1993): 3788-3789. Full Text
  - Casey, CP, Widenhoefer, RA, and Hallenbeck, SL. "Conversion of acetylene to a triple bridged ethylidyne ligand on the cluster Cp*₃Co₃(μ₂-H)₃(μ ₃-H)." Organometallics 12, no. 10 (1993): 3788-3789.
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reaction of NO with Cp*3Co3(μ-H)4 preserves the tricobalt cluster and produces Cp*3Co3(μ3-NO)2." Inorganica Chimica Acta 212, no. 1-2 (January 1, 1993): 81-85. Full Text
  - Casey, CP, Widenhoefer, RA, and Hayashi, RK. "Reaction of NO with Cp*₃Co₃(μ-H)₄ preserves the tricobalt cluster and produces Cp*₃Co₃(μ₃-NO)₂." Inorganica Chimica Acta 212, no. 1-2 (1993): 81-85. Full Text
  - KERSTEN, JL, RHEINGOLD, AL, THEOPOLD, KH, CASEY, CP, WIDENHOEFER, RA, and HOP, C. "[CP-ASTERISK-CO=COCP-ASTERISK] IS A HYDRIDE." ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 31, no. 10 (October 1992): 1341-1343. Full Text Link to Item
  - Kersten, JL, Rheingold, AL, Theopold, KH, Casey, CP, Widenhoefer, RA, and Hop, CECA. "'[Cp*Co=CoCp*]' is a Hydride." Angew. Chem. 104 (1992): 1364-. (Academic Article)
  - Kersten, JL, Rheingold, AL, Theopold, KH, Casey, CP, Widenhoefer, RA, and Hop, CECA. "“[Cp^*CoCoCp^*]” is a Hydride." Angewandte Chemie International Edition in English 31, no. 10 (January 1, 1992): 1341-1343. Full Text
  - Casey, CP, Widenhoefer, RA, and O'Connor, JM. "Phosphine induced cyclopentadienyl ring slippage catalyzes CO insertion into a methyl rhenium compound to produce an acetyl rhenium compound." Journal of Organometallic Chemistry 428, no. 1-2 (April 28, 1992): 99-105. Full Text
  - Widenhoefer, RA, Zhong, HA, and Buchwald, SL. "Direct observation of C-O reductive elimination from palladium aryl alkoxide complexes to form aryl ethers." Journal of the American Chemical Society 119, no. 29 (July 23, 1997): 6787-6795. Full Text
  - Widenhoefer, RA, and Buchwald, SL. "Electronic dependence of C-O reductive elimination from palladium (aryl)neopentoxide complexes." Journal of the American Chemical Society 120, no. 26 (July 8, 1998): 6504-6511. Full Text
  - Widenhoefer, RA, and Perch, NS. "Silane-promoted cycloisomerization of functionalized 1,6-dienes catalyzed by a cationic (π-allyl)palladium complex." Organic Letters 1, no. 7 (October 7, 1999): 1103-1105. Full Text
- Book Sections
  - Widenhoefer, RA, and Bender, CF. "Silane-initiated carbocyclization catalyzed by transition metal complexes." In Comprehensive Organometallic Chemistry III, 367-410. December 1, 2007.
- Conference Papers
  - Brooner, REM, and Widenhoefer, RA. "Synthesis and solution behavior of cationic, two-coordinate gold(I) p-complexes bearing a triphenylphosphine ligand." August 19, 2012. Link to Item
  - Mukherjee, P, and Widenhoefer, RA. "Gold(I)-catalyzed enantioselective intramolecular dehydrative amination of allylic alcohols with carbamates." August 19, 2012. Link to Item
  - Widenhoefer, RA. "Cationic, two-coordinate gold p-complexes containing an N-heterocyclic carbene ligand." 244th National Fall Meeting of the American-Chemical-Society (ACS). Philadelphia, PA. August 19, 2012 - August 23, 2012.: AMER CHEMICAL SOC, August 19, 2012. Link to Item
  - Brown, TJ, Sugie, A, and Widenhoefer, RA. "Cationic, two-coordinate gold(I) P -allene complexes: Syntheses, X-ray crystal structures, and dynamic solution behavior." August 28, 2011. Link to Item
  - Brown, TJ, and Widenhoefer, RA. "Dinuclear gold(I) s,P -acetylide complex formation via gold(I) P -alkyne complexes: Kinetics and mechanism." August 28, 2011. Link to Item
  - Butler, KL, and Widenhoefer, RA. "Platinum(II)-catalyzed intermolecular hydroamination of allenes." August 28, 2011. Link to Item
  - Lee, SD, and Widenhoefer, RA. "Gold(I)-catalyzed enantioselective intermolecular hydroamination of unactivated 1-alkenes with cyclic ureas." August 28, 2011. Link to Item
  - Mukherjee, P, and Widenhoefer, RA. "Gold(I)-catalyzed intermolecular amination of allylic alcohols with cyclic ureas and related nucleophiles." August 22, 2010. Link to Item
  - Duncan, AN, and Widenhoefer, RA. "Mechanistic studies and scrope of gold(I)-catalyzed intermolecular hydroamination of allenes with arylamines." March 21, 2010. Link to Item
  - Zhang, Z, and Widenhoefer, RA. "ORGN 42-Gold(I)-catalyzed dynamic kinetic enantioselective hydroamination." August 17, 2008. Link to Item
  - Zhang, Z, and Widenhoefer, RA. "ORGN 589-Gold(I)-catalyzed intermolecular hydroalkoxylation of allenes." August 17, 2008. Link to Item
  - Bender, CF, Hudson, WB, and Widenhoefer, RA. "PRES 11-Platinum catalyzed intramolecular hydroamination of unactivated olefines with secondary alkylamines." April 6, 2008. Link to Item
  - Zhang, Z, and Widenhoefer, RA. "INOR 555-Gold-catalyzed enantioselective cyclization of allenyl alcohols." August 19, 2007. Link to Item
  - Bender, CF, and Widenhoefer, RA. "ORGN 188-Au(I)-catalyzed intramolecular hydroamination of unactivated olefins with carboxamides." September 10, 2006. Link to Item
  - Bender, CF, and Widenhoefer, RA. "INOR 437-Mechanism for the intramolecular hydroamination of unactivated olefins with secondary alkylamines." September 10, 2006. Link to Item
  - Kinder, RE, Han, X, Qian, H, and Widenhoefer, RA. "ORGN 922-Au(I)-Catalyzed intramolecular hydroamination of allenyl carbamates." September 10, 2006. Link to Item
  - Zhang, Z, and Widenhoefer, RA. "ORGN 187-Au(I)-catalyzed cyclizations of allenyl alcohols." September 10, 2006. Link to Item
  - Kinder, RE, and Widenhoefer, RA. "Rhodium-catalyzed asymmetric borylative cyclization of 1,6-enynes." March 26, 2006. Link to Item
  - Bender, CF, and Widenhoefer, RA. "Intramolecular hydroamination of unactivated olefins with secondary alkylamines." August 28, 2005. Link to Item
  - Liu, C, and Widenhoefer, RA. "Scope and mechanism of Pd-catalyzed arylation/carboalkoxylation of unactivated olefins with indoles and pyrrols." August 28, 2005. Link to Item
  - Qian, H, and Widenhoefer, RA. "Platinum-catalyzed intermolecular hydroamination of vinyl arenes with carboxamides." 230th National Meeting of the American-Chemical-Society. Washington, DC. August 28, 2005 - September 1, 2005.: AMER CHEMICAL SOC, August 28, 2005. Link to Item
  - Han, XQ, and Widenhoefer, RA. "Asymmetric intramolecular alkylation of indoles with unactivated olefins." 229th National Meeting of the American-Chemical-Society (ACS). San Diego, CA. March 13, 2005 - March 17, 2005.: AMER CHEMICAL SOC, March 13, 2005. Link to Item
  - Liu, C, Han, XQ, Wang, X, and Widenhoefer, RA. "Platinum-catalyzed intramolecular alkylation of indoles with unactivated olefins." August 22, 2004. Link to Item
  - Goj, LA, Perch, NS, and Widenhoefer, RA. "Effect of terminal substitution on the intramolecular carbometallation of 5-hexenyl palladium chelate complexes." September 2003. Link to Item
  - Chakrapani, H, and Widenhoefer, RA. "Rh-catalyzed cyclization/hydrosilylation of functionalized enynes." August 18, 2002. Link to Item
  - Pei, T, Wang, X, Han, XQ, Qian, H, and Widenhoefer, RA. "Palladium-catalyzed addition of stabilized carbon nucleophiles to unactivated olefins." August 18, 2002. Link to Item
  - Pei, T, and Widenhoefer, RA. "Palladium-catalyzed intramolecular addition of 1,3-diones to unactivated olefins." April 7, 2002. Link to Item
  - Wang, X, Stankovich, S, and Widenhoefer, RA. "Palladium-catalyzed ring-opening cyclization/hydrosilylation of 1-cyclopropyl-1,6-heptadienes to form (E)-1-butenyl cyclopentanes." April 7, 2002. Link to Item
  - Goj, LA, and Widenhoefer, RA. "Role of palladium cyclopentyl chelate complexes in the palladium-catalyzed cycloisomerization of functionalized 1,6-dienes." August 2001. Link to Item
  - Pei, T, and Widenhoefer, RA. "Palladium-catalyzed asymmetric cyclization/hydrosilylation of functionalized 1,6-dienes employing benzhydryldimethylsilane." : AMER CHEMICAL SOC, August 1, 2001. Link to Item
  - Perch, NS, and Widenhoefer, RA. "Direct observation of the intramolecular carbometallation of a palladium alkyl-olefin chelate complex." August 2001. Link to Item
  - Widenhoefer, RA, Madine, JW, Wang, X, and Chakrapani, H. "Platinum-catalyzed cyclization/hydrosilylation of functionalized diynes." August 2001. Link to Item
  - Widenhoefer, RA, DeCarli, MA, and Gross, PM. "Tandem cyclization/hydrosilylation of functionalized 1,6-dienes catalyzed by a cationic palladium complex." August 23, 1998. Link to Item
  - Widenhoefer, RA, Krzyzanowska, BK, and Webb-Wood, G. "Palladium-catalyzed cyclization of 4-pentenylsilanes to form six-membered silicon heterocycles." August 23, 1998. Link to Item
  - WIDENHOEFER, RA, ZHONG, HA, and BUCHWALD, SL. "THE SYNTHESIS AND REDUCTIVE ELIMINATION OF PALLADIUM AMINE COMPLEXES." August 20, 1995. Link to Item
  - CASEY, CP, HALLENBECK, SL, and WIDENHOEFER, RA. "KINETICS AND MECHANISM OF THE FORMATION OF THE BIS(ETHYLIDYNE) TRICOBALT CLUSTER CP-ASTERISK-C-3(CO3)(MU-3-CCH3)2 FROM ACETYLENE AND CP-ASTERISK-C-3(CO3)(MU-2-H)3(MU-3-H)." April 2, 1995. Link to Item
  - CASEY, CP, WIDENHOEFER, RA, and HALLENBECK, SL. "CONVERSION OF ACETYLENE TO A TRIPLE BRIDGED ETHYLIDYNE LIGAND ON THE CLUSTER CP-ASTERISK-3CO3(MU-3-H)(MU-2-H)3." August 22, 1993. Link to Item
Teaching & Mentoring
Recent Courses
- CHEM 202L9: Organic Chemistry Laboratory 2019
- CHEM 202L: Organic Chemistry II 2019
- CHEM 393: Research Independent Study 2019
- CHEM 394: Research Independent Study 2019
- CHEM 401L: Analytical Chemistry Laboratory 2019
- CHEM 493: Research Independent Study 2019
- CHEM 494: Research Independent Study 2019
- CHEM 533: Nuclear Magnetic Resonance 2019
- CHEM 531: Organic Chemistry 2017
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