Overview
The general focus of our work is the development of new interventional technologies and new interventional clinical methods. Specifically, we have developed new interventional devices including balloons, stents and drug delivery stents for the treatment of both coronary and peripheral vascular disease.
In the experimental program, the pig, dog, and sheep models are being used under eight separate Animal Care Committee approved protocols to develop a variety of interventional devices and techniques including an effective drug delivery stent to reduce or eliminate acute vessel closure and long term restenosis.
The clinical program is designed to develop the highest quality peripheral vascular program focusing on application of cardiac interventional techniques and technologies in the peripheral circulation.
Two of our most important current clinical randomized trials are: A Randomized Study to Compare the Safety and Efficacy of Renal Artery Stenting to Balloon Angioplasty Alone and Carotid Artery Stenting vs. Endarterectomy.
Special areas of expertise and interest include development of coronary and peripheral vascular devices. Specifically, methods to overcome the problem of in-stent restenosis with drug delivery stents as well as the development of new peripheral vascular stents and other interventional devices. Specific areas of interest include carotid artery revascularization with endoluminal stents and the application of stents to obstructive arterial disease in various locations within the peripheral vasculature. Another area of interest includes the development of minimally invasive coronary artery bypass procedures in conjunction with members of the Thoracic Surgery division at Duke.
Cardiovascular Intervention
Stents
Peripheral Vascular Intervention
Minimally Invasive Coronary Artery Bypass Surgery
Drug Delivery Stents
In the experimental program, the pig, dog, and sheep models are being used under eight separate Animal Care Committee approved protocols to develop a variety of interventional devices and techniques including an effective drug delivery stent to reduce or eliminate acute vessel closure and long term restenosis.
The clinical program is designed to develop the highest quality peripheral vascular program focusing on application of cardiac interventional techniques and technologies in the peripheral circulation.
Two of our most important current clinical randomized trials are: A Randomized Study to Compare the Safety and Efficacy of Renal Artery Stenting to Balloon Angioplasty Alone and Carotid Artery Stenting vs. Endarterectomy.
Special areas of expertise and interest include development of coronary and peripheral vascular devices. Specifically, methods to overcome the problem of in-stent restenosis with drug delivery stents as well as the development of new peripheral vascular stents and other interventional devices. Specific areas of interest include carotid artery revascularization with endoluminal stents and the application of stents to obstructive arterial disease in various locations within the peripheral vasculature. Another area of interest includes the development of minimally invasive coronary artery bypass procedures in conjunction with members of the Thoracic Surgery division at Duke.
Cardiovascular Intervention
Stents
Peripheral Vascular Intervention
Minimally Invasive Coronary Artery Bypass Surgery
Drug Delivery Stents
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2002 - Present
Medicine, Cardiology,
Medicine
Recent Publications
Biomedical innovation: a risky business at risk.
Journal Article Sci Transl Med · August 17, 2011 Regulatory and financial challenges conspire to stall the development and market approval of breakthrough medical products. Inconsistent parameters are used to assess the safety and efficacy of drugs, biologics, and devices; this glitch in the system intro ... Full text Link to item CiteRecent Grants
Coronary Blood Flow Velocity In Ischemic Heart Disease
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1989 - 1990View All Grants
Education, Training & Certifications
Wayne State University ·
1976
M.D.