Scholars@Duke
Sabino Zani Jr.

Sabino Zani Jr.

Associate Professor of Surgery
Surgical Oncology
sabino.zani@duke.edu
DUMC 3247, 487 Seeley G. Mudd Bldg, Durham, NC 27710
DUMC 3247, 456E Seeley G. Mudd Bldg, Durham, NC 27710

Selected Publications

Perioperative and Oncologic Outcomes of Hepatic Arterial Infusion (HAI) Pump Chemotherapy for Patients with Unresectable Colorectal Liver Metastases at an Expanding HAI Program.

Conference Ann Surg Oncol · November 20, 2024 BACKGROUND: Hepatic arterial infusion (HAI) is an established treatment for patients with unresectable colorectal liver metastases (uCRLM). Until recently, HAI was only performed at a limited number of centers. We previously reported early outcomes suggest ... Full text Link to item Cite

Interobserver Variability in the International Study Group for Pancreatic Surgery (ISGPS)-Defined Complications After Pancreatoduodenectomy: An International Cross-Sectional Multicenter Study.

Journal Article Ann Surg · November 1, 2024 OBJECTIVE: To determine the interobserver variability for complications of pancreatoduodenectomy as defined by the International Study Group for Pancreatic Surgery (ISGPS) and others. BACKGROUND: Good interobserver variability for the definitions of surgic ... Full text Link to item Cite

Evolution of Initial Treatment for Desmoid Tumors.

Journal Article Ann Surg Oncol · November 2024 INTRODUCTION: Desmoid tumors (DTs) are rare, fibroblastic cell proliferations that can exhibit locally aggressive behavior but lack metastatic potential. Initial management has traditionally involved upfront resection; however, contemporary guidelines and ... Full text Link to item Cite

Animal Models Within Surgical Simulation: A Novel Approach to the 3 Rs.

Journal Article J Surg Res · November 2024 INTRODUCTION: Development of technical skills is a vital component of surgical residency. The use of animal tissues for operative simulation leads to both the loss of animal life and financial costs for the institution. We hypothesized that maximizing tiss ... Full text Link to item Cite

Survival Outcomes and Genetic Characteristics of Resected Pancreatic Acinar Cell Carcinoma.

Journal Article Annals of surgical oncology · November 2024 BackgroundPancreatic acinar cell carcinoma (pACC) is a rare neoplasm of the exocrine pancreas. There is a dearth of information about tumor characteristics and patient outcomes. This study describes the clinical characteristics, genetic alteration ... Full text Cite

Abstract B052: Single-cell and spatial analysis of the immune landscape unveils a subset of potentially tumor-reactive T cells in patients with localized PDAC

Conference Cancer Research · September 15, 2024 AbstractEven in its localized stages, pancreatic ductal adenocarcinoma (PDAC) is virtually incurable, characterized by early dissemination and disease recurrence. The liver is the most common site of metasta ... Full text Cite

Genome-Derived Ampullary Adenocarcinoma Classifier and Postresection Prognostication.

Journal Article JAMA Surg · September 11, 2024 IMPORTANCE: Ampullary adenocarcinoma (AA) is characterized by clinical and genomic heterogeneity. A previously developed genomic classifier defined biologically distinct phenotypes with greater accuracy than standard histologic classification. External val ... Full text Link to item Cite

Metroticket approach in a retrospective cohort study to predict overall survival after surgical resection for intermediate stage hepatocellular carcinoma.

Journal Article Int J Surg · September 6, 2024 BACKGROUND: Surgical resection is a curative therapy for early-stage hepatocellular carcinoma (HCC) patients meeting the Milan criteria as well as a widely used therapy in intermediate-stage HCC. However, intermediate-stage HCC encompasses a wide spectrum ... Full text Link to item Cite

The role of ERAS in robotic pancreaticoduodenectomy.

Journal Article Lancet Gastroenterol Hepatol · July 2024 Full text Link to item Cite

Are enhanced recovery protocols after pancreatoduodenectomy still efficient when applied in elderly patients? A systematic review and individual patient data meta-analysis.

Journal Article J Hepatobiliary Pancreat Sci · May 2024 BACKGROUND: This meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared to conventional care on postoperative outcomes in patients aged 70 years or older undergoing pancreatoduodenectomy (PD). METHODS: Five data ... Full text Link to item Cite

Contemporary trends and outcomes after liver transplantation and resection for intrahepatic cholangiocarcinoma.

Journal Article J Gastrointest Surg · May 2024 BACKGROUND: Liver transplantation (LT) has been shown to be superior to resection in highly selected patients with perihilar cholangiocarcinoma (CCA), yet has traditionally been contraindicated for intrahepatic CCA (iCCA). Herein, we aimed to examine conte ... Full text Link to item Cite

Simple versus radical cholecystectomy and survival for pathologic stage T1B gallbladder cancer.

Journal Article HPB (Oxford) · April 2024 BACKGROUND: Radical cholecystectomy is recommended for T1B and greater gallbladder cancer, however, there are conflicting reports on the utility of extended resection for T1B disease. Herein, we characterize outcomes following simple and radical cholecyste ... Full text Link to item Cite

Defining the learning curve for robotic pancreaticoduodenectomy for a single surgeon following experience with laparoscopic pancreaticoduodenectomy.

Journal Article J Robot Surg · March 16, 2024 Robotic pancreaticoduodenectomy (RPD) has a learning curve of approximately 30-250 cases to reach proficiency. The learning curve for laparoscopic pancreaticoduodenectomy (LPD) at Duke University was previously defined as 50 cases. This study describes the ... Full text Link to item Cite

Abstract B022: A platform to characterize hepatic immunity reveals variation in hepatic infiltration of tumor expanded T cells in “localized” PDAC

Conference Cancer Research · January 16, 2024 AbstractEven in its earliest stages, pancreatic ductal adenocarcinoma (PDAC) is an essentially incurable disease due to the presence of disseminated, yet radiographically occult cancer cells in the setting o ... Full text Cite

Tumor size and survival in intrahepatic cholangiocarcinoma treated with surgical resection or ablation.

Journal Article J Surg Oncol · December 2023 OBJECTIVES: We performed a retrospective analysis within a national cancer registry on outcomes following resection or ablation for intrahepatic cholangiocarcinoma (iCCA). METHODS: The National Cancer Database was queried for patients with clinical stage I ... Full text Link to item Cite

Development of a prospective biliary dashboard to compare performance and surgical cost.

Journal Article Surg Endosc · November 2023 BACKGROUND: Transparency around surgeon level data may align healthcare delivery with quality care for patients. Biliary surgery includes numerous procedures performed by both general surgeons and subspecialists alike. Cholecystectomy is a common surgical ... Full text Link to item Cite

Comparing Survival After Resection, Ablation, and Radiation in Small Intrahepatic Cholangiocarcinoma.

Journal Article Ann Surg Oncol · October 2023 BACKGROUND: Hepatectomy is the cornerstone of curative-intent treatment for intrahepatic cholangiocarcinoma (ICC). However, in patients unable to be resected, data comparing efficacy of alternatives including thermal ablation and radiation therapy (RT) rem ... Full text Open Access Link to item Cite

Impact of surgical approach on short- and long-term outcomes in gastroenteropancreatic neuroendocrine carcinomas.

Journal Article HPB (Oxford) · October 2023 BACKGROUND: Literature is lacking on the impact of advancements in minimally invasive surgery (MIS) on outcomes for patients with gastroenteropancreatic neuroendocrine carcinomas (GEP-NECs). Herein, we compared perioperative and oncologic outcomes among pa ... Full text Open Access Link to item Cite

A minimally invasive approach for management of pancreaticoduodenal artery and gastroduodenal artery aneurysm with celiac artery occlusion.

Journal Article J Vasc Surg Cases Innov Tech · September 2023 Management of pancreaticoduodenal artery aneurysms (PDAAs) and gastroduodenal artery aneurysms (GDAAs) with concomitant celiac occlusion represents a challenging clinical scenario. Here, we describe a 62-year-old female with PDAA and GDAA complicated by ce ... Full text Link to item Cite

Robotic Distal Pancreatectomy: A Novel Standard of Care? Benchmark Values for Surgical Outcomes From 16 International Expert Centers.

Journal Article Ann Surg · August 1, 2023 BACKGROUND AND OBJECTIVE: Robotic distal pancreatectomy (DP) is an emerging attractive approach, but its role compared with laparoscopic or open surgery remains unclear. Benchmark values are novel and objective tools for such comparisons. The aim of this s ... Full text Link to item Cite

Trends in Receipt of Adjuvant Chemotherapy and its Impact on Survival in Resected Biliary Tract Cancers.

Journal Article Ann Surg Oncol · August 2023 BACKGROUND: Resection remains the cornerstone of curative-intent treatment for biliary tract cancers (BTCs). However, recent randomized data also support a role for adjuvant chemotherapy (AC). This study aimed to characterize trends in the use of AC and su ... Full text Link to item Cite

Hepatic artery infusion for unresectable colorectal cancer liver metastases: Palliation and conversion.

Journal Article Surgery · August 2023 Patients with unresectable colorectal liver metastases are commonly treated with systemic chemotherapy to convert their disease to an operable state. Unfortunately, many patients remain unresectable after first-line chemotherapy and resort to second- and t ... Full text Link to item Cite

A novel low-cost model of superficial abscess for trainee education in incision and drainage.

Journal Article Surg Open Sci · August 2023 BACKGROUND: Proficiency in ultrasound usage is quickly becoming an expectation in multiple residency programs: emergency medicine, obstetrics-gynecology, surgery, and internal medicine. There is a lack of affordable training devices for ultrasound training ... Full text Link to item Cite

Closed Incision Negative Pressure Therapy to Reduce Surgical Site Infection in High-Risk Gastrointestinal Surgery: A Randomized Controlled Trial.

Journal Article J Am Coll Surg · April 1, 2023 BACKGROUND: Despite institutional perioperative bundles and national infection prevention guidelines, surgical site infection (SSI) after a major abdominal operation remains a significant source of morbidity. Negative pressure therapy (NPT) has revolutioni ... Full text Link to item Cite

Evolution in Management of Upfront Treatment For Desmoid Tumors

Conference ANNALS OF SURGICAL ONCOLOGY · 2023 Cite

Hepatic Artery Infusion Pumps: A Surgical Toolkit for Intraoperative Decision-Making and Management of Hepatic Artery Infusion-Specific Complications.

Journal Article Ann Surg · December 1, 2022 BACKGROUND: Hepatic artery infusion (HAI) is a liver-directed therapy that delivers high-dose chemotherapy to the liver through the hepatic arterial system for colorectal liver metastases and intrahepatic cholangiocarcinoma. Utilization of HAI is rapidly e ... Full text Link to item Cite

Surgical resection is associated with improved long-term survival of patients with resectable pancreatic head cancer compared to multiagent chemotherapy.

Journal Article HPB (Oxford) · July 2022 BACKGROUND: Standard of care for resectable pancreatic cancer is a combination of surgical resection (SR) and multiagent chemotherapy (MCT). We aim to determine whether SR or MCT is associated with superior survival for patients receiving only single-modal ... Full text Link to item Cite

Combined Primary Resection with Hepatic Artery Infusion Pump Implantation Is Safe for Unresectable Colorectal Liver Metastases.

Journal Article J Gastrointest Surg · April 2022 BACKGROUND: Colorectal liver metastases (CRLM) are the most common cause of disease-specific mortality in patients with colorectal cancer. Hepatic artery infusion (HAI) combined with systemic chemotherapy improves survival for these patients. The safety of ... Full text Link to item Cite

Quality of Life Associated with Open vs Minimally Invasive Pancreaticoduodenectomy: A Prospective Pilot Study.

Journal Article J Am Coll Surg · April 1, 2022 BACKGROUND: This prospective study was designed to compare quality of life (QoL) among patients who underwent open (O-PD) vs minimally invasive pancreaticoduodenectomy (MI-PD), using a combination of validated qualitative and quantitative methodologies. ST ... Full text Link to item Cite

Impact of enhanced recovery protocols after pancreatoduodenectomy: meta-analysis.

Journal Article Br J Surg · February 24, 2022 BACKGROUND: This individual-patient data meta-analysis investigated the effects of enhanced recovery after surgery (ERAS) protocols compared with conventional care on postoperative outcomes in patients undergoing pancreatoduodenectomy. METHODS: The Cochran ... Full text Link to item Cite

Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.

Journal Article Ann Clin Transl Neurol · February 2022 OBJECTIVE: Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cereb ... Full text Open Access Link to item Cite

Perioperative and oncologic outcomes of hepatic artery infusion pump therapy at an expanding HAI program.

Conference Journal of Clinical Oncology · February 1, 2022 120 Background: Hepatic artery infusion (HAI) is a liver directed therapy to treat unresectable or resected colorectal liver metastases (CRLM) and unresectable intrahepatic cholangiocarcinoma (ICC). Historically, HAI has only bee ... Full text Cite

Empiric nasogastric decompression after pancreaticoduodenectomy is not necessary.

Journal Article HPB (Oxford) · December 2021 BACKGROUND: The aim of the present study was to evaluate the impact of routine NGT decompression after PD on postoperative outcomes in the era of an enhanced recovery after surgery (ERAS) protocol. MATERIALS AND METHODS: A retrospective review of all patie ... Full text Link to item Cite

CT Radiomic Features of Superior Mesenteric Artery Involvement in Pancreatic Ductal Adenocarcinoma: A Pilot Study.

Journal Article Radiology · December 2021 Background Current imaging methods for prediction of complete margin resection (R0) in patients with pancreatic ductal adenocarcinoma (PDAC) are not reliable. Purpose To investigate whether tumor-related and perivascular CT radiomic features improve preope ... Full text Open Access Link to item Cite

Unifying the Hepatopancreatobiliary Surgery Fellowship Curriculum via Delphi Consensus.

Journal Article J Am Coll Surg · September 2021 BACKGROUND: Hepatopancreatobiliary (HPB) Fellowship training in the Americas consists of 3 distinctive routes with variable curricula: Surgical Oncology Fellowship via the Society of Surgical Oncology (SSO), Abdominal Transplant Surgery Fellowship via the ... Full text Link to item Cite

The Legacy of Joseph A. Moylan, M.D.: "It's About Everyone Else".

Journal Article Ann Surg Open · March 2021 The history of modern American surgery is marked by larger-than-life pioneers who have made transformative contributions to our field. These extraordinary individuals have been known primarily for their technical and clinical mastery, development of novel ... Full text Link to item Cite

Validation of the 8th Edition American Joint Commission on Cancer (AJCC) Gallbladder Cancer Staging System: Prognostic Discrimination and Identification of Key Predictive Factors.

Journal Article Cancers (Basel) · February 1, 2021 The scope of our study was to compare the predictive ability of American Joint Committee on Cancer (AJCC) 7th and 8th edition in gallbladder carcinoma (GBC) patients, investigate the effect of AJCC 8th nodal status on the survival, and identify risk factor ... Full text Link to item Cite

Implementation of a Hepatic Artery Infusion Program: Initial Patient Selection and Perioperative Outcomes of Concurrent Hepatic Artery Infusion and Systemic Chemotherapy for Colorectal Liver Metastases.

Journal Article Ann Surg Oncol · December 2020 BACKGROUND: Hepatic artery infusion (HAI) combined with systemic chemotherapy is a treatment strategy for patients with unresectable liver-only or liver-dominant colorectal liver metastases (CRLM). Although HAI has previously been performed in only a few c ... Full text Link to item Cite

Improved overall survival is still observed in patients receiving delayed adjuvant chemotherapy after pancreaticoduodenectomy for pancreatic adenocarcinoma.

Journal Article HPB (Oxford) · November 2020 BACKGROUND: Adjuvant chemotherapy (AC) is associated with improved survival following resection of pancreatic adenocarcinoma but is frequently delayed or deferred due to perioperative complications or patient deconditioning. The aim of this study was to as ... Full text Link to item Cite

Delaying surgery for patients with a previous SARS-CoV-2 infection.

Journal Article The British journal of surgery · November 2020 Full text Cite

Jejunostomy Tube Insertion for Enteral Nutrition: Comparison of Outcomes after Laparoscopic versus Radiologic Insertion.

Journal Article J Vasc Interv Radiol · July 2020 PURPOSE: To retrospectively compare technical success and major complication rates of laparoscopically versus radiologically inserted jejunostomy tubes. MATERIALS AND METHODS: In this single-institution retrospective study, 115 patients (60 men; mean age, ... Full text Link to item Cite

CD226 Expression is Associated with Increased Survival in Pancreatic Cancer

Conference ANNALS OF SURGICAL ONCOLOGY · February 1, 2020 Link to item Cite

Vibration testing of laparoscopic surgical instruments under varying grip pressures

Conference Conference Proceedings of the Society for Experimental Mechanics Series · January 1, 2020 Many devices use vibration to provide sensory cues to a human user. In applications, such as smart phones, the vibratory sensory cue is somewhat simple and needs only to exceed a known threshold to signal the user; however, applications that require an ind ... Full text Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Prognostic significance of primary tumor sidedness in patients undergoing liver resection for metastatic colorectal cancer.

Journal Article HPB (Oxford) · December 2019 BACKGROUND: Approximately 38% of patients with colorectal cancer will develop isolated liver metastases. Sidedness of colon tumor is identified in non-metastatic and unresected metastatic cancers as predictive of survival, yet its dedicated analysis in res ... Full text Link to item Cite

Robotic-Assisted Nissen Fundoplication with the Senhance® Surgical System: Technical Aspects and Early Results.

Journal Article Surg Technol Int · November 10, 2019 INTRODUCTION: Robotic-assisted surgery continues to evolve. Technical advantages are reported for intracorporal suturing, a technique with a long learning curve in conventional laparoscopy. The success of laparoscopic fundoplication relies on precise sutur ... Link to item Cite

Robotic cholecystectomy: first experience with the new Senhance robotic system.

Journal Article J Robot Surg · June 2019 This retrospective study was performed to evaluate the safety and feasibility of the new Senhance robotic system (Transenterix) for robotic cholecystectomy. Our series is the first experience with cholecystectomies utilizing this new platform. From May 201 ... Full text Link to item Cite

Robotic Inguinal Hernia Repair (TAPP) First Experience with the New Senhance Robotic System.

Journal Article Surg Technol Int · May 15, 2019 INTRODUCTION: This retrospective study was performed to evaluate the safety and feasibility of the new Senhance Robotic System (TransEnterix Inc., Morrisville, North Carolina) for inguinal hernia repairs using the transabdominal preperitoneal approach. MAT ... Link to item Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

Objective Assessment of the Early Stages of the Learning Curve for the Senhance Surgical Robotic System.

Journal Article J Surg Educ · 2019 OBJECTIVE: The purpose of this research is to study the early stages of the Senhance learning curve to report how force feedback impacts learning rate. This serves as an exploratory investigation into assumptions that fellows and faculty will adjust faster ... Full text Link to item Cite

Laparoscopic versus open gastrectomy with D2 lymph node dissection for advanced gastric cancer: a systematic review.

Journal Article J BUON · 2019 PURPOSE: Review of the literature collecting trials comparing laparoscopic (LGD2) and open D2 gastrectomies (OGD2) for the treatment of advanced gastric cancer (AGC). METHODS: Randomized control trials (RCTs) and non-RCTs comparing LGD2 with OGD2 for AGC t ... Link to item Cite

Robotic inguinal hernia repair (TAPP)— first experience with the new senhance™ robotic system

Journal Article Surgical Technology International · January 1, 2019 Introduction: This retrospective study was performed to evaluate the safety and feasibility of the new Sen-hance ™ Robotic System (TransEnterix Inc., Morrisville, North Carolina) for inguinal hernia repairs using the transabdominal preperitoneal approach. ... Cite

Robotic-assisted nissen fundoplication with the senhance® surgical system: Technical aspects and early results

Journal Article Surgical Technology International · January 1, 2019 Introduction: Robotic-assisted surgery continues to evolve. Technical advantages are reported for intracor-poral suturing, a technique with a long learning curve in conventional laparoscopy. The success of laparoscopic fundoplication relies on precise sutu ... Cite

Sample Entropy of Speed Power Spectrum as a Measure of Laparoscopic Surgical Instrument Trajectory Smoothness.

Journal Article Annu Int Conf IEEE Eng Med Biol Soc · July 2018 In this study the complexity of the speed power spectrum is assessed as a metric for measuring trajectory smoothness. There are a variety of published methods for analyzing trajectory smoothness but many lack validity. This preliminary study took an inform ... Full text Link to item Cite

Robot-assisted repair of diaphragmatic hernias following ventricular assist device implantation.

Journal Article J Surg Case Rep · February 2018 Use of ventricular assist devices (VADs) is increasingly common, as is the need for surgeons to be familiar with the management of common complications in this population. Nonetheless, repair of diaphragmatic hernias which commonly develop following VAD im ... Full text Link to item Cite

Laparoscopic skill assessment of practicing surgeons prior to enrollment in a surgical trial of a new laparoscopic procedure.

Journal Article Surg Endosc · August 2017 BACKGROUND: Outcomes of surgical trials hinge on surgeon selection and their underlying expertise. Assessment of expertise is paramount. We investigated whether surgeons' performance measured by the fundamentals of laparoscopic surgery (FLS) assessment pro ... Full text Link to item Cite

Safety and Feasibility of Minimally Invasive Inguinal Lymph Node Dissection in Patients With Melanoma (SAFE-MILND): Report of a Prospective Multi-institutional Trial.

Journal Article Ann Surg · January 2017 BACKGROUND: Minimally invasive inguinal lymph node dissection (MILND) is a novel approach to inguinal lymphadenectomy. SAFE-MILND (NCT01500304) is a multicenter, phase I/II clinical trial evaluating the safety and feasibility of MILND for patients with mel ... Full text Link to item Cite

Training High-Volume Melanoma Surgeons to Perform a Novel Minimally Invasive Inguinal Lymphadenectomy: Report of a Prospective Multi-Institutional Trial.

Journal Article J Am Coll Surg · March 2016 BACKGROUND: Minimally invasive inguinal lymphadenectomy (MILND) is a novel procedure with the potential to decrease surgical morbidity compared with the traditional open approach. The current study examined the feasibility of a combined didactic and hands- ... Full text Link to item Cite

Safety and Feasibility of Minimally Invasive Inguinal Lymph Node Dissection in Patients With Melanoma (SAFE-MILND): Report of a Prospective Multi-institutional Trial.

Journal Article Ann Surg · February 25, 2016 BACKGROUND: Minimally invasive inguinal lymph node dissection (MILND) is a novel approach to inguinal lymphadenectomy. SAFE-MILND (NCT01500304) is a multicenter, phase I/II clinical trial evaluating the safety and feasibility of MILND for patients with mel ... Full text Link to item Cite

How the radiologist can add value in the evaluation of the pre- and post-surgical pancreas.

Journal Article Abdom Imaging · October 2015 Disease involving the pancreas can be a significant diagnostic challenge to the interpreting radiologist. Moreover, the majority of disease processes involving the pancreas carry high significant morbidity and mortality either due to their natural process ... Full text Link to item Cite

Gangrenous cholecystitis: a contemporary review.

Journal Article J Surg Res · July 2015 BACKGROUND: Despite the established superiority of laparoscopic cholecystectomy (LC) for acute cholecystitis, gangrenous cholecystitis (GC) is commonly treated with open cholecystectomy (OC). This study aimed to characterize outcomes of GC in the modern er ... Full text Link to item Cite

Total laparoscopic retrieval of inferior vena cava filter.

Journal Article SAGE Open Med Case Rep · 2015 While there is some local variability in the use of inferior vena cava filters and there has been some evolution in the indications for filter placement over time, inferior vena cava filters remain a standard option for pulmonary embolism prophylaxis. Indi ... Full text Link to item Cite

Wound classification reporting in HPB surgery: can a single word change public perception of institutional performance?

Journal Article HPB (Oxford) · December 2014 INTRODUCTION: The drive to improve outcomes and the inevitability of mandated public reporting necessitate uniform documentation and accurate databases. The reporting of wound classification in patients undergoing hepato-pancreatico-biliary (HPB) surgery a ... Full text Link to item Cite

Defining the learning curve for team-based laparoscopic pancreaticoduodenectomy.

Conference Ann Surg Oncol · November 2014 BACKGROUND: The purpose of this study was to define the learning curves for laparoscopic pancreaticoduodenectomy (LPD) with and without laparoscopic reconstruction, using paired surgical teams consisting of advanced laparoscopic-trained surgeons and advanc ... Full text Link to item Cite

Modest advances in survival for patients with colorectal-associated peritoneal carcinomatosis in the era of modern chemotherapy.

Journal Article J Surg Oncol · March 2013 BACKGROUND: The treatment of metastatic colorectal cancer (CRC) has evolved rapidly over the last decade, with combination chemotherapy and targeted biologic agents leading to significant improvements in survival. Despite these advances, little is known ab ... Full text Link to item Cite

A role for hepatic metastasectomy in stage IV melanoma and breast cancer: reestablishing the surgical modality.

Journal Article Oncology (Williston Park) · November 15, 2011 Historically, liver-related metastases associated with melanoma or breast cancer have portended a poor prognosis. Many affected patients are not considered for surgical resection based on the extent and multifocal nature of their disease. For this patient ... Link to item Cite

Recurrent granulosa cell tumor presenting with spontaneous retroperitoneal hemorrhage: A case report.

Journal Article Gynecol Oncol Case Rep · 2011 ► Patients diagnosed with granulosa cell tumor require long-term surveillance. ► Recurrent granulosa cell tumor may present as spontaneous retroperitoneal hemorrhage. ► We present an unusual case of recurrent granulosa cell tumor resulting in retroperitone ... Full text Link to item Cite

International surgery and the University of Connecticut experience: lessons from a short-term surgical mission.

Journal Article Conn Med · March 2010 BACKGROUND: Surgery is gradually gaining recognition within the international public health community as an essential component to sustainable improvements in health care in resource-poor areas. In this article, we document the University of Connecticut ex ... Link to item Cite

Snowblower injuries to the hand: epidemiology, patterns of injury, and strategies for prevention.

Journal Article Ann Plast Surg · December 2008 Snowblowers injure approximately 5000 people a year and can cause devastating hand injuries. Even with added safety measures and warnings on modern snowblowers, hand injuries are still occurring at an alarming rate. We have reviewed our series of snowblowe ... Full text Link to item Cite

Diversity and detection of nitrate assimilation genes in marine bacteria.

Journal Article Appl Environ Microbiol · November 2001 A PCR approach was used to construct a database of nasA genes (called narB genes in cyanobacteria) and to detect the genetic potential for heterotrophic bacterial nitrate utilization in marine environments. A nasA-specific PCR primer set that could be used ... Full text Link to item Cite

ORGANIZATION OF THE nif GENES OF THE NONHETEROCYSTOUS CYANOBACTERIUM TRICHODESMIUM SP. IMS101.

Journal Article J Phycol · August 26, 2000 An approximately 16-kb fragment of the Trichodesmium sp. IMS101 (a nonheterocystous filamentous cyanobacterium) "conventional"nif gene cluster was cloned and sequenced. The gene organization of the Trichodesmium and Anabaena variabilis vegetative (nif 2) n ... Full text Link to item Cite

Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101.

Journal Article Plant Mol Biol · September 1999 The daily cycle of nitrogenase expression in the marine filamentous nonheterocystous cyanobacterium Trichodesmium spp. is controlled by a circadian rhythm. We evaluated the rhythm of two key photosynthesis genes, psbA of photosystem II and psaA of photosys ... Full text Link to item Cite

New Nitrogen-Fixing Microorganisms Detected in Oligotrophic Oceans by Amplification of Nitrogenase (nifH) Genes.

Other Appl Environ Microbiol · December 1998 [This corrects the article on p. 3444 in vol. 64, PMID: 9726895.]. ... Full text Link to item Cite

New nitrogen-fixing microorganisms detected in oligotrophic oceans by amplification of Nitrogenase (nifH) genes.

Journal Article Appl Environ Microbiol · September 1998 Oligotrophic oceanic waters of the central ocean gyres typically have extremely low dissolved fixed inorganic nitrogen concentrations, but few nitrogen-fixing microorganisms from the oceanic environment have been cultivated. Nitrogenase gene (nifH) sequenc ... Full text Link to item Cite