Scholars@Duke
Sabran Masoud

Sabran Masoud

House Staff
Surgery
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Selected Publications

Contemporary trends and outcomes after liver transplantation and resection for intrahepatic cholangiocarcinoma.

Journal Article J Gastrointest Surg · May 2024 BACKGROUND: Liver transplantation (LT) has been shown to be superior to resection in highly selected patients with perihilar cholangiocarcinoma (CCA), yet has traditionally been contraindicated for intrahepatic CCA (iCCA). Herein, we aimed to examine conte ... Full text Link to item Cite

Social Vulnerability Index and Survivorship after Colorectal Cancer Resection.

Journal Article J Am Coll Surg · April 1, 2024 BACKGROUND: Race and socioeconomic status incompletely identify patients with colorectal cancer (CRC) at the highest risk for screening, treatment, and mortality disparities. Social vulnerability index (SVI) was designed to delineate neighborhoods requirin ... Full text Link to item Cite

Tumor size and survival in intrahepatic cholangiocarcinoma treated with surgical resection or ablation.

Journal Article J Surg Oncol · December 2023 OBJECTIVES: We performed a retrospective analysis within a national cancer registry on outcomes following resection or ablation for intrahepatic cholangiocarcinoma (iCCA). METHODS: The National Cancer Database was queried for patients with clinical stage I ... Full text Link to item Cite

Comparing Survival After Resection, Ablation, and Radiation in Small Intrahepatic Cholangiocarcinoma.

Journal Article Ann Surg Oncol · October 2023 BACKGROUND: Hepatectomy is the cornerstone of curative-intent treatment for intrahepatic cholangiocarcinoma (ICC). However, in patients unable to be resected, data comparing efficacy of alternatives including thermal ablation and radiation therapy (RT) rem ... Full text Open Access Link to item Cite

Impact of Tumor Size and Management on Survival in Small Gastric Gastrointestinal Stromal Tumors.

Journal Article J Gastrointest Surg · October 2023 BACKGROUND: Society guidelines remain inconsistent on the role of endoscopic and radiographic surveillance as an alternative to surgical resection of small gastric gastrointestinal stromal tumors (GISTs). Herein, we aimed to assess survival among patients ... Full text Link to item Cite

Primary tumor resection improves survival of gastrointestinal neuroendocrine carcinoma patients with nonresected liver metastases.

Journal Article J Surg Oncol · May 2023 BACKGROUND: The role of primary tumor resection (PTR) in the survival of gastrointestinal neuroendocrine carcinoma (GI-NEC) patients with liver metastases only remains poorly defined. Therefore, we investigated the impact of PTR on the survival of GI-NEC p ... Full text Open Access Link to item Cite

Greater Compliance With Early Sepsis Management is Associated With Safer Care and Shorter Hospital Stay.

Journal Article J Healthc Qual · November 2021 This retrospective, cross-sectional study of U.S. hospitals in Medicare's Inpatient Quality Reporting Program aimed to determine whether variation in Sepsis/Septic Shock (Bundle SEP-1) compliance is linked to hospital size and measures of safety and operat ... Full text Link to item Cite

Improved overall survival is still observed in patients receiving delayed adjuvant chemotherapy after pancreaticoduodenectomy for pancreatic adenocarcinoma.

Journal Article HPB (Oxford) · November 2020 BACKGROUND: Adjuvant chemotherapy (AC) is associated with improved survival following resection of pancreatic adenocarcinoma but is frequently delayed or deferred due to perioperative complications or patient deconditioning. The aim of this study was to as ... Full text Link to item Cite

Retreatment with talimogene laherparepvec for advanced melanoma.

Journal Article Immunotherapy · November 2020 Aim: Talimogene laherparepvec (T-VEC) is a genetically modified oncolytic herpesvirus approved for the treatment of unresectable, locoregionally advanced and recurrent melanoma. There is little relevant literature in the context of retreatment with T-VEC. ... Full text Link to item Cite

Gratitude at Work: Prospective Cohort Study of a Web-Based, Single-Exposure Well-Being Intervention for Health Care Workers.

Journal Article J Med Internet Res · May 14, 2020 BACKGROUND: Emotional exhaustion (EE) in health care workers is common and consequentially linked to lower quality of care. Effective interventions to address EE are urgently needed. OBJECTIVE: This randomized single-exposure trial examined the efficacy of ... Full text Open Access Link to item Cite

Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size.

Conference Ann Surg Oncol · December 2019 BACKGROUND: Talimogene laherparepvec (T-VEC) is the first injectable oncolytic viral therapy approved for in-transit melanoma metastasis, with a reported overall response rate (ORR) of 25% and complete response rate (CRR) of 10%. To ascertain the role of p ... Full text Link to item Cite

Correction to: Sentinel Lymph Node Biopsy and Completion Lymph Node Dissection for Melanoma.

Journal Article Curr Treat Options Oncol · August 29, 2019 The original version of this article, which published in Current Treatment Options in Oncology, Volume 19, Issue 11, November 2018, contained an error within the Conflict of Interest statements. It was originally stated that "Norma E. Farrow received suppo ... Full text Link to item Cite

Gratitude at Work: Prospective Cohort Study of a Web-Based, Single-Exposure Well-Being Intervention for Health Care Workers (Preprint)

Journal Article · July 19, 2019 BACKGROUNDEmotional exhaustion (EE) in health care workers is common and consequentially linked to lower quality of care. Effective interventions to address EE are urgently needed. ... Full text Open Access Cite

Sentinel Lymph Node Biopsy and Completion Lymph Node Dissection for Melanoma.

Journal Article Curr Treat Options Oncol · September 19, 2018 This review critically evaluates recent trials which have challenged the practice of completion lymph node dissection (CLND) for melanoma patients diagnosed with regional metastasis by positive sentinel lymph node biopsy (SLNB). Two trials in the last 2 ye ... Full text Link to item Cite

Variation in the use of laparoscopy with inguinal hernia repairs in a sample of pediatric patients at children's hospitals.

Journal Article Journal of pediatric urology · April 2018 Introduction/backgroundMetachronous contralateral inguinal hernias (MCH) occur in approximately 10% of pediatric patients following unilateral inguinal hernia repairs (UIHR). Laparoscopic evaluation of the contralateral internal ring is a method o ... Full text Cite

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.

Journal Article Nature medicine · July 2014 Hedgehog signaling drives oncogenesis in several cancers, and strategies targeting this pathway have been developed, most notably through inhibition of Smoothened (SMO). However, resistance to Smoothened inhibitors occurs by genetic changes of Smoothened o ... Full text Cite

BET bromodomain inhibition of MYC-amplified medulloblastoma.

Journal Article Clinical cancer research : an official journal of the American Association for Cancer Research · February 2014 PurposeMYC-amplified medulloblastomas are highly lethal tumors. Bromodomain and extraterminal (BET) bromodomain inhibition has recently been shown to suppress MYC-associated transcriptional activity in other cancers. The compound JQ1 inhibits BET ... Full text Cite