Journal ArticleBiostatistics · October 1, 2024
Modern longitudinal studies collect multiple outcomes as the primary endpoints to understand the complex dynamics of the diseases. Oftentimes, especially in clinical trials, the joint variation among the multidimensional responses plays a significant role ...
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Journal ArticleEBioMedicine · July 2024
BACKGROUND: Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors in combination with traditional endocrine therapy (ET) are now the recommended first-line treatment for hormone receptor (HR)-positive and HER2-negative metastatic breast cancer (MBC). However, th ...
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Journal ArticleAnnual Review of Statistics and Its Application · March 10, 2023
Modern studies from a variety of fields record multiple functional observations according to either multivariate, longitudinal, spatial, or time series designs. We refer to such data as second-generation functional data because their analysis—unli ...
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