Samantha Thomas | Scholars@Duke

Samantha Thomas
Biostatistician, Senior

Samantha primarily works with physicians in the Duke Cancer Institute (DCI), specifically in research of Endocrine Neoplasia and Breast Cancer. She is also the coordinator for the Biostatistics Core Training and Internship Program (BCTIP). Her professional experience involves study design, analysis, and reporting of clinical trials and observational studies. Her specific areas of interest include modeling of non-linear associations and application of partitioning analyses to identify homogeneous patient groups.

Office Hours

The Biostatistics Core holds office hours Mondays 9-10am in Hock Plaza 11016.

Current Appointments & Affiliations

Biostatistician, Senior, Biostatistics & Bioinformatics, Basic Science Departments

Contact Information

2424 Erwin Road, 8033 Hock Plaza Duke Box 2717, Durham, NC 27710
samantha.thomas@duke.edu +1 919 668 5892
LinkedIN

Research
Selected Grants
- Randomized Trial of Optimal Type of Aerobic Training in Breast Cancer awarded by Memorial Sloan Kettering Cancer Center 2015 - 2018
- Aerobic Training During or After Adjuvant Therapy: A Randomized Trial awarded by National Institutes of Health 2012 - 2014
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Wahidi, Momen M., Samantha Thomas, and Bercedis Peterson. “Reply to Gilbert et al.: The Impact of the ASAP Trial: Maybe We Shouldn't Act So Quickly..” American Journal of Respiratory and Critical Care Medicine 197, no. 1 (January 2018): 143–44. https://doi.org/10.1164/rccm.201706-1190le.
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  - Pontius, Lauren N., Taofik O. Oyekunle, Samantha M. Thomas, Michael T. Stang, Randall P. Scheri, Sanziana A. Roman, and Julie A. Sosa. “Projecting Survival in Papillary Thyroid Cancer: A Comparison of the Seventh and Eighth Editions of the American Joint Commission on Cancer/Union for International Cancer Control Staging Systems in Two Contemporary National Patient Cohorts..” Thyroid : Official Journal of the American Thyroid Association 27, no. 11 (November 2017): 1408–16. https://doi.org/10.1089/thy.2017.0306.
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  - Shah, Syed A., Mohamed A. Adam, Samantha M. Thomas, Randall P. Scheri, Michael T. Stang, Julie A. Sosa, and Sanziana A. Roman. “Racial Disparities in Differentiated Thyroid Cancer: Have We Bridged the Gap?.” Thyroid : Official Journal of the American Thyroid Association 27, no. 6 (June 2017): 762–72. https://doi.org/10.1089/thy.2016.0626.
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  - Wahidi, Momen M., Chakravarthy Reddy, Lonny Yarmus, David Feller-Kopman, Ali Musani, R Wesley Shepherd, Hans Lee, et al. “Randomized Trial of Pleural Fluid Drainage Frequency in Patients with Malignant Pleural Effusions. The ASAP Trial..” Am J Respir Crit Care Med 195, no. 8 (April 15, 2017): 1050–57. https://doi.org/10.1164/rccm.201607-1404OC.
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  - Elmariah, Hany, Samantha Thomas, Joel C. Boggan, Aimee Zaas, and Jonathan Bae. “The Burden of Burnout..” American Journal of Medical Quality : The Official Journal of the American College of Medical Quality 32, no. 2 (March 2017): 156–62. https://doi.org/10.1177/1062860615625802.
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  - O’Donnell, Christopher, Samantha Thomas, Crystal Johnson, Lalit Verma, Jonathan Bae, and David Gallagher. “Incorporating Patient Acuity Rating Score Into Patient Handoffs and the Correlation With Rapid Responses and Unexpected ICU Transfers..” American Journal of Medical Quality : The Official Journal of the American College of Medical Quality 32, no. 2 (March 2017): 122–28. https://doi.org/10.1177/1062860616630809.
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  - Susko, Matthew, Jason Lee, Joseph Salama, Samantha Thomas, Hope Uronis, David Hsu, John Migaly, Christopher Willett, Brian Czito, and Manisha Palta. “The Use of Re-irradiation in Locally Recurrent, Non-metastatic Rectal Cancer..” Annals of Surgical Oncology 23, no. 11 (October 2016): 3609–15. https://doi.org/10.1245/s10434-016-5250-z.
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  - Qin, Rosie, Adam Olson, Bhavana Singh, Samantha Thomas, Steven Wolf, Nrupen A. Bhavsar, Brent A. Hanks, Joseph K. Salama, and April K. S. Salama. “Safety and Efficacy of Radiation Therapy in Advanced Melanoma Patients Treated With Ipilimumab..” International Journal of Radiation Oncology, Biology, Physics 96, no. 1 (September 2016): 72–77. https://doi.org/10.1016/j.ijrobp.2016.04.017.
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  - Pontius, Lauren N., Linda M. Youngwirth, Samantha M. Thomas, Randall P. Scheri, Sanziana A. Roman, and Julie A. Sosa. “Lymphovascular invasion is associated with survival for papillary thyroid cancer..” Endocrine Related Cancer 23, no. 7 (July 2016): 555–62. https://doi.org/10.1530/erc-16-0123.
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  - Ruel, Ewa, Samantha Thomas, Michaela A. Dinan, Jennifer M. Perkins, Sanziana A. Roman, and Julie Ann Sosa. “Knowledge of pathologically versus clinically negative lymph nodes is associated with reduced use of radioactive iodine post-thyroidectomy for low-risk papillary thyroid cancer..” Endocrine 52, no. 3 (June 2016): 579–86. https://doi.org/10.1007/s12020-015-0826-0.
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  - Ahmadzia, H. K., S. M. Thomas, A. P. Murtha, R. P. Heine, and L. R. Brancazio. “Obstetric hemorrhage survey: Attitudes and practices of maternal-fetal medicine fellows..” Journal of Neonatal Perinatal Medicine 9, no. 2 (May 2016): 133–37. https://doi.org/10.3233/npm-16915119.
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  - Adam, Mohamed Abdelgadir, Samantha Thomas, Linda Youngwirth, Terry Hyslop, Shelby D. Reed, Randall P. Scheri, Sanziana A. Roman, and Julie A. Sosa. “Is There a Minimum Number of Thyroidectomies a Surgeon Should Perform to Optimize Patient Outcomes?.” Annals of Surgery, March 8, 2016.
  - Koelwyn, Graeme J., Nia C. Lewis, Susan L. Ellard, Lee W. Jones, Jinelle C. Gelinas, J Douglass Rolf, Bernie Melzer, et al. “Ventricular-Arterial Coupling in Breast Cancer Patients After Treatment With Anthracycline-Containing Adjuvant Chemotherapy.” Oncologist 21, no. 2 (February 2016): 141–49. https://doi.org/10.1634/theoncologist.2015-0352.
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  - Leung, Jason H., Jui-Chih Chang, Sadé M. Bell, Zoie E. Holzknecht, Samantha M. Thomas, Mary Lou Everett, William Parker, R Duane Davis, and Shu S. Lin. “The role of soluble and insoluble gastric fluid components in the pathogenesis of obliterative bronchiolitis in rat lung allografts..” Transpl Int 29, no. 2 (February 2016): 253–61. https://doi.org/10.1111/tri.12715.
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  - Goffredo, Paolo, Christa Jillard, Samantha Thomas, Randall P. Scheri, Julie Ann Sosa, and Sanziana Roman. “Minimally invasive follicular carcinoma: predictors of vascular invasion and impact on patterns of care..” Endocrine 51, no. 1 (January 2016): 123–30. https://doi.org/10.1007/s12020-015-0649-z.
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  - Garman, Katherine S., Leandi Kruger, Samantha Thomas, Marzena Swiderska-Syn, Barry K. Moser, Anna Mae Diehl, and Shannon J. McCall. “Ductal metaplasia in oesophageal submucosal glands is associated with inflammation and oesophageal adenocarcinoma..” Histopathology 67, no. 6 (December 2015): 771–82. https://doi.org/10.1111/his.12707.
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  - Goffredo, Paolo, Samantha M. Thomas, Mohamed Abdelgadir Adam, Julie A. Sosa, and Sanziana A. Roman. “Impact of Timeliness of Resection and Thyroidectomy Margin Status on Survival for Patients with Anaplastic Thyroid Cancer: An Analysis of 335 Cases..” Annals of Surgical Oncology 22, no. 13 (December 2015): 4166–74. https://doi.org/10.1245/s10434-015-4742-6.
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  - Sullivan, Brian, David Ming, Joel C. Boggan, Ryan D. Schulteis, Samantha Thomas, Josh Choi, and Jonathan Bae. “An evaluation of physician predictions of discharge on a general medicine service..” Journal of Hospital Medicine 10, no. 12 (December 2015): 808–10. https://doi.org/10.1002/jhm.2439.
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  - Goffredo, P., M. A. Adam, S. M. Thomas, R. P. Scheri, J. A. Sosa, and S. A. Roman. “Patterns of Use and Short-Term Outcomes of Minimally Invasive Surgery for Malignant Pheochromocytoma: A Population-Level Study..” World Journal of Surgery 39, no. 8 (August 2015): 1966–73. https://doi.org/10.1007/s00268-015-3040-6.
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  - Mercer, Tim, Jon Bae, Joanna Kipnes, Maureen Velazquez, Samantha Thomas, and Noppon Setji. “The highest utilizers of care: individualized care plans to coordinate care, improve healthcare service utilization, and reduce costs at an academic tertiary care center..” J Hosp Med 10, no. 7 (July 2015): 419–24. https://doi.org/10.1002/jhm.2351.
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  - Jiang, Betty S., Paul J. Speicher, Samantha Thomas, Paul J. Mosca, Amy P. Abernethy, and Douglas S. Tyler. “Quality of life after isolated limb infusion for in-transit melanoma of the extremity..” Ann Surg Oncol 22, no. 5 (May 2015): 1694–1700. https://doi.org/10.1245/s10434-014-3979-9.
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  - Ruel, Ewa, Samantha Thomas, Michaela Dinan, Jennifer M. Perkins, Sanziana A. Roman, and Julie Ann Sosa. “Adjuvant radioactive iodine therapy is associated with improved survival for patients with intermediate-risk papillary thyroid cancer..” The Journal of Clinical Endocrinology and Metabolism 100, no. 4 (April 2015): 1529–36. https://doi.org/10.1210/jc.2014-4332.
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  - Tuchman, Sascha A., Amy Lane, Whitney E. Hornsby, Caroline Bishop, Samantha Thomas, James E. Herndon, Gwynn Long, Cristina Gasparetto, and Lee W. Jones. “Quantitative measures of physical functioning after autologous hematopoietic stem cell transplantation in multiple myeloma: a feasibility study..” Clinical Lymphoma, Myeloma & Leukemia 15, no. 2 (February 2015): 103–9. https://doi.org/10.1016/j.clml.2014.09.002.
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  - Mahmood, Kamran, Momen M. Wahidi, Samantha Thomas, Angela Christine Argento, Neil A. Ninan, Emily C. Smathers, and Scott L. Shofer. “Therapeutic bronchoscopy improves spirometry, quality of life, and survival in central airway obstruction..” Respiration; International Review of Thoracic Diseases 89, no. 5 (January 2015): 404–13. https://doi.org/10.1159/000381103.
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  - Ahmadzia, Homa Khorrami, Samantha Marie Thomas, Annie Melissa Dude, Chad Aaron Grotegut, and Brita Katherine Boyd. “Prediction of birthweight from third-trimester ultrasound in morbidly obese women..” Am J Obstet Gynecol 211, no. 4 (October 2014): 431.e1-431.e7. https://doi.org/10.1016/j.ajog.2014.06.041.
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  - Kelsey, C. R., J. M. Scott, A. Lane, E. Schwitzer, M. J. West, S. Thomas, J. E. Herndon, et al. “Cardiopulmonary exercise testing prior to myeloablative allo-SCT: a feasibility study..” Bone Marrow Transplantation 49, no. 10 (October 2014): 1330–36. https://doi.org/10.1038/bmt.2014.159.
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  - Siddiqui, Nazema Y., and Samantha M. Thomas. “In reply..” Obstetrics and Gynecology 124, no. 4 (October 2014). https://doi.org/10.1097/aog.0000000000000488.
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  - Siddiqui, Nazema Y., and Samantha M. Thomas. “Validity and Reliability of the Robotic Objective Structured Assessment of Technical Skills Reply.” Obstetrics and Gynecology 124, no. 4 (October 2014): 839–839. https://doi.org/10.1097/AOG.0000000000000488.
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  - Boggan, Joel C., George Cheely, Bimal R. Shah, Randy Heffelfinger, Deanna Springall, Samantha M. Thomas, Aimee Zaas, and Jonathan Bae. “A Novel Approach to Practice-Based Learning and Improvement Using a Web-Based Audit and Feedback Module..” Journal of Graduate Medical Education 6, no. 3 (September 2014): 541–46. https://doi.org/10.4300/JGME-D-14-00016.1.
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  - Kenjale, Aarti A., Whitney E. Hornsby, Theresa Crowgey, Samantha Thomas, James E. Herndon, Michel G. Khouri, Amy R. Lane, et al. “Pre-exercise participation cardiovascular screening in a heterogeneous cohort of adult cancer patients..” The Oncologist 19, no. 9 (September 2014): 999–1005. https://doi.org/10.1634/theoncologist.2014-0078.
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  - Ahmadzia, H. K., S. M. Thomas, R. P. Heine, A. P. Murtha, and L. R. Brancazio. “Survey of peripartum hysterectomy experiences: anticipated, unplanned, or averted..” Obstetrics and Gynecology 123 Suppl 1 (May 2014). https://doi.org/10.1097/01.aog.0000447104.53791.85.
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  - Jones, Lee W., Whitney E. Hornsby, Stephen J. Freedland, Amy Lane, Miranda J. West, Judd W. Moul, Michael N. Ferrandino, et al. “Effects of nonlinear aerobic training on erectile dysfunction and cardiovascular function following radical prostatectomy for clinically localized prostate cancer..” European Urology 65, no. 5 (May 2014): 852–55. https://doi.org/10.1016/j.eururo.2013.11.009.
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  - Khouri, M. G., W. E. Hornsby, N. Risum, E. J. Velazquez, S. Thomas, A. Lane, J. M. Scott, et al. “Utility of 3-dimensional echocardiography, global longitudinal strain, and exercise stress echocardiography to detect cardiac dysfunction in breast cancer patients treated with doxorubicin-containing adjuvant therapy.” Breast Cancer Research and Treatment 143, no. 3 (February 1, 2014): 531–39. https://doi.org/10.1007/s10549-013-2818-1.
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  - Khouri, Michel G., Whitney E. Hornsby, Niels Risum, Eric J. Velazquez, Samantha Thomas, Amy Lane, Jessica M. Scott, et al. “Utility of 3-dimensional echocardiography, global longitudinal strain, and exercise stress echocardiography to detect cardiac dysfunction in breast cancer patients treated with doxorubicin-containing adjuvant therapy..” Breast Cancer Research and Treatment 143, no. 3 (February 2014): 531–39. https://doi.org/10.1007/s10549-013-2818-1.
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  - Peel, Amanda B., Samantha M. Thomas, Kim Dittus, Lee W. Jones, and Susan G. Lakoski. “Cardiorespiratory fitness in breast cancer patients: a call for normative values..” Journal of the American Heart Association 3, no. 1 (January 13, 2014). https://doi.org/10.1161/JAHA.113.000432.
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  - Jones, L. W., W. E. Hornsby, S. J. Freedland, A. Lane, M. J. West, J. W. Moul, M. N. Ferrandino, et al. “Effects of nonlinear aerobic training on erectile dysfunction and cardiovascular function following radical prostatectomy for clinically localized prostate cancer.” European Urology 65, no. 5 (January 1, 2014): 852–55. https://doi.org/10.1016/j.eururo.2013.11.009.
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  - Kelsey, C. R., J. M. Scott, A. Lane, E. Schwitzer, M. J. West, S. Thomas, J. E. Herndon, et al. “Cardiopulmonary exercise testing prior to myeloablative allo-SCT: A feasibility study.” Bone Marrow Transplantation 49, no. 10 (January 1, 2014): 1330–36. https://doi.org/10.1038/bmt.2014.159.
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  - Denehy, Linda, Whitney E. Hornsby, James E. Herndon, Samantha Thomas, Neal E. Ready, Catherine L. Granger, Lauren Valera, Aarti A. Kenjale, Neil D. Eves, and Lee W. Jones. “Prognostic validation of the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index in inoperable non-small-cell lung cancer..” Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer 8, no. 12 (December 2013): 1545–50. https://doi.org/10.1097/jto.0000000000000032.
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  - Lakoski, Susan G., Carolyn E. Barlow, Graeme J. Koelwyn, Whitney E. Hornsby, Jesse Hernandez, Laura F. Defina, Nina B. Radford, et al. “The influence of adjuvant therapy on cardiorespiratory fitness in early-stage breast cancer seven years after diagnosis: the Cooper Center Longitudinal Study..” Breast Cancer Research and Treatment 138, no. 3 (April 2013): 909–16. https://doi.org/10.1007/s10549-013-2478-1.
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- Other Articles
  - Goffredo, Paolo, Samantha M. Thomas, Michaela A. Dinan, Jennifer M. Perkins, Sanziana A. Roman, and Julie A. Sosa. “Patterns of use and cost for inappropriate radioactive iodine treatment for thyroid cancer in the United States: use and misuse..” Jama Internal Medicine, April 2015. https://doi.org/10.1001/jamainternmed.2014.8020.
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- Conference Papers
  - Adam, Mohamed Abdelgadir, Samantha Thomas, Linda Youngwirth, Theodore Pappas, Sanziana A. Roman, and Julie A. Sosa. “Defining a Hospital Volume Threshold for Minimally Invasive Pancreaticoduodenectomy in the United States..” In Jama Surgery, 152:336–42, 2017. https://doi.org/10.1001/jamasurg.2016.4753.
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  - Anand, S., S. Thomas, T. Hyslop, K. Corbet, C. Gasparetto, G. Long, A. Morris, et al. “Transplantation of Ex vivo Expanded Umbilical Cord Blood (Nicord) Results in Decreased Infection Burden and Hospital Length of Stay in the First 100 Days.” In Bone Marrow Transplantation, 51:S52–53. NATURE PUBLISHING GROUP, 2016.
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  - Koelwyn, Graeme J., Nia C. Lewis, Susan L. Ellard, Lee W. Jones, Jinelle C. Gelinas, J Douglass Rolf, Bernie Melzer, et al. “Ventricular-Arterial Coupling in Breast Cancer Patients After Treatment With Anthracycline-Containing Adjuvant Chemotherapy..” In The Oncologist, 21:141–49, 2016. https://doi.org/10.1634/theoncologist.2015-0352.
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  - Adam, Mohamed, Samantha M. Thomas, Sanziana A. Roman, and Julie Ann Sosa. “Is There a Minimum Case Volume of Thyroidectomies Associated with Superior Outcomes? An Analysis of 37,118 Cases in the US.” In Journal of the American College of Surgeons, 221:S60–61. Elsevier BV, 2015. https://doi.org/10.1016/j.jamcollsurg.2015.07.132.
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  - Swaminathan, Aparna C., Joel C. Boggan, Samantha Thomas, and Jonathan Bae. “"WE FOLLOW-UP": IMPROVING FOLLOW-UP, COMMUNICATION AND DOCUMENTATION OF OUTPATIENT TEST RESULTS BY DUKE RESIDENTS.” In Journal of General Internal Medicine, 30:S46–47. SPRINGER, 2015.
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  - Ahmadzia, Homa, Evelyn Lockhart, Chad Grotegut, Samantha Thomas, Ian Welsby, Maureane Hoffman, Amy Murtha, and Geeta Swamy. “Effect of antifibrinolytic drugs on in vitro clot formation among peripartum women.” In American Journal of Obstetrics and Gynecology, 212:S96–S96. MOSBY-ELSEVIER, 2015.
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  - Wheeler, Sarahn, Brian Antczak, Homa Ahmadzia, Samantha Thomas, Geeta Swamy, Amy Murtha, and Patrick Seed. “709: Race, latency, and fetal membrane microbiota diversity in preterm premature rupture of membranes.” In American Journal of Obstetrics and Gynecology, 212:S346–S346. Elsevier BV, 2015. https://doi.org/10.1016/j.ajog.2014.10.915.
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  - Ahmadzia, H. K., S. M. Thomas, A. M. Dude, C. A. Grotegut, and B. K. Boyd. “Prediction of birthweight from third-trimester ultrasound in morbidly obese women.” In American Journal of Obstetrics and Gynecology, 211:431.e1-431.e7, 2014. https://doi.org/10.1016/j.ajog.2014.06.041.
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  - Kelsey, C. R., J. Scott, A. Lane, E. Schwitzer, M. West, S. Thomas, J. Herndon, et al. “Cardiopulmonary Exercise Testing Prior to Myeloablative Allogeneic Stem Cell Transplantation Using Total Body Irradiation: A Feasibility Study.” In International Journal of Radiation Oncology*Biology*Physics, 90:S681–S681. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.2003.
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  - Ahmadzia, Homa, Emily Patel, Huizi Lian, Samantha Thomas, Terrence Allen, Chad Grotegut, and Brita Boyd. “137: Can the gestation-adjusted projection (GAP) method be used in obese to super morbidly obese women to predict birth weight?.” In American Journal of Obstetrics and Gynecology, 210:S82–83. Elsevier BV, 2014. https://doi.org/10.1016/j.ajog.2013.10.170.
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  - Ahmadzia, Homa, Huizi Lian, Sarah Moustafa, Ann Dude, Jennifer Gilner, Samantha Thomas, Terrence Allen, Chad Grotegut, and Brita Boyd. “138: Prediction of birth weight by early versus late third trimester ultrasound in morbidly obese women.” In American Journal of Obstetrics and Gynecology, 210:S83–S83. Elsevier BV, 2014. https://doi.org/10.1016/j.ajog.2013.10.171.
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  - Thompson, Jennifer, Kimberly Fortner, Brian Antczak, Liping Feng, Samantha Thomas, Chad Grotegut, Patrick Seed, and Amy Murtha. “791: Immunohistochemical distribution of toll-like receptors in human fetal membranes.” In American Journal of Obstetrics and Gynecology, 210:S387–S387. Elsevier BV, 2014. https://doi.org/10.1016/j.ajog.2013.10.824.
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Selected Grants

Selected Publications

Academic Articles

Other Articles

Conference Papers