Journal ArticleeLife · November 2019
Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking differe ...
Full textOpen AccessCite
Journal ArticleF1000Research · November 15, 2018
The vimentin gene (
VIM
) encodes one of the 71 human intermediate filament (IF) proteins, which are the building blocks of highly ordered, dynamic, and cell type- ...
Full textOpen AccessCite