Scholars@Duke
Samia Aleem

Samia Aleem

Assistant Professor of Pediatrics
Pediatrics, Neonatology
samia.aleem@duke.edu
2424 Erwin Road, Hock Plaza I, Durham, NC 27705

Selected Publications

Epidemiology and outcomes of bacterial meningitis in the neonatal intensive care unit.

Journal Article J Perinatol · December 2024 OBJECTIVE: Examine pathogen distribution, antibiotic resistance patterns, and hospital outcomes of infants with bacterial meningitis in neonatal intensive care units (NICUs) in the US from 2013-2018. STUDY DESIGN: Infants were divided into 2 groups based o ... Full text Link to item Cite

The association of the room air challenge with long-term outcomes in extremely preterm infants.

Journal Article J Perinatol · September 2024 OBJECTIVE: Evaluate the association between results of the room air (RA) challenge and death, respiratory morbidity, and neurodevelopmental impairment (NDI) at 2 years' corrected age. STUDY DESIGN: Cohort study of infants born <27 weeks' gestational age wh ... Full text Link to item Cite

Trends in morbidities of late preterm infants in the neonatal intensive care unit.

Journal Article J Perinatol · November 2023 OBJECTIVE: To characterize demographics and trends in length of stay (LOS), morbidities, and mortality in late preterm infants. STUDY DESIGN: Cohort study of infants born between 34 0/7 and 36 6/7 weeks gestation between 1999 and 2018 without major congeni ... Full text Link to item Cite

Association of clinical signs of chorioamnionitis with histological chorioamnionitis and neonatal outcomes.

Journal Article The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · December 2022 BackgroundChorioamnionitis is a risk factor for fetal and neonatal outcomes. Therefore, predicting histological chorioamnionitis (HCA) and neonatal outcomes using clinical parameters could be helpful in management and preventing morbidities.Ob ... Full text Cite

Cost-effectiveness of Pulmonary Rehabilitation Among US Adults With Chronic Obstructive Pulmonary Disease.

Journal Article JAMA Netw Open · June 1, 2022 IMPORTANCE: Pulmonary rehabilitation (PR) after exacerbation of chronic obstructive pulmonary disease (COPD) is effective in reducing COPD hospitalizations and mortality while improving health-related quality of life, yet use of PR remains low. Estimates o ... Full text Link to item Cite

Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series.

Journal Article Pediatr Infect Dis J · April 1, 2022 BACKGROUND: There has been a 291% relative increase in congenital syphilis (CS) cases in the United States from 2015 to 2019. Although the majority of affected fetuses/infants are stillborn or are asymptomatic, a subset is born with severe clinical illness ... Full text Link to item Cite

Invasive fungal infections in neonates: a review.

Journal Article Pediatr Res · January 2022 Invasive fungal infections remain the leading causes of morbidity and mortality in neonates, especially preterm and very low birth weight infants. Most invasive fungal infections are due to Candida or Aspergillus species, and other fungi are increasingly r ... Full text Link to item Cite

Infection-related stillbirth: an update on current knowledge and strategies for prevention.

Journal Article Expert Rev Anti Infect Ther · September 2021 Introduction: Infections during pregnancy are a preventable public health concern globally, with the highest burden occurring in low- and middle-income countries. Despite clear interventions to reduce these infections, their impact on preventing stillbirth ... Full text Link to item Cite

Vasoactive medications in extremely low gestational age neonates during the first postnatal week.

Journal Article J Perinatol · September 2021 OBJECTIVE: The management of early hypotension in extremely low gestational age neonates (ELGANs) varies greatly between centers. The objective of this study was to provide updated data on the use of vasoactive medications in ELGANs during the first postna ... Full text Link to item Cite

The use of supplemental hydrocortisone in the management of persistent pulmonary hypertension of the newborn.

Journal Article J Perinatol · April 2021 OBJECTIVE: Characterize association between hydrocortisone receipt and hospital outcomes of infants with persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN: Cohort study of infants ≥34 weeks with PPHN who received inhaled nitric oxide at ... Full text Link to item Cite

An Update on the Prevention and Management of Bronchopulmonary Dysplasia.

Journal Article Pediatric Health Med Ther · 2021 Bronchopulmonary dysplasia (BPD) is a common morbidity affecting preterm infants and is associated with substantial long-term disabilities. There has been no change in the incidence of BPD over the past 20 years, despite improvements in survival and other ... Full text Link to item Cite

Infection control and other stewardship strategies in late onset sepsis, necrotizing enterocolitis, and localized infection in the neonatal intensive care unit.

Journal Article Semin Perinatol · December 2020 Suspected or proven late onset sepsis, necrotizing enterocolitis, urinary tract infections, and ventilator associated pneumonia occurring after the first postnatal days contribute significantly to the total antibiotic exposures in neonatal intensive care u ... Full text Link to item Cite

Neonatology: A global perspective

Book · January 1, 2020 In 2017, approximately 2.5 million neonates died, and most of them died within the first week of life. Preterm births continue to be the leading cause of neonatal mortality. Whilst evidence-based interventions for success are well documented in the literat ... Full text Cite

Outpatient antibiotic prescribing patterns in pediatric academic and community practices.

Journal Article Am J Infect Control · September 2019 Little is known about antibiotic prescribing differences between academic and community outpatient settings. This retrospective, cross-sectional chart review compares compliance with Infectious Diseases Society of America and American Academy of Pediatrics ... Full text Link to item Cite

When to Include a Lumbar Puncture in the Evaluation for Neonatal Sepsis.

Journal Article Neoreviews · March 2019 Meningitis is a devastating infection in infants and is linked to adverse long-term outcomes. The prevalence of meningitis is variable and depends on gestational age, postnatal age, and clinical setting. Early diagnosis and treatment with appropriate antib ... Full text Link to item Cite

A Review of External Assistance and Aid Effectiveness for Maternal and Child Health: Challenges and Opportunities

Scholarly Edition · 2013 This paper primarily focuses on how global funding has supported interventions that have proven to be successful in reducing maternal, newborn, and child mortality around the world. The growth rate of development assistance targeted towards these specific ... Cite