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Samuel Jarrod Francis

Assistant Professor of Emergency Medicine
Emergency Medicine

Current Appointments & Affiliations


Assistant Professor of Emergency Medicine · 2021 - Present Emergency Medicine, Clinical Science Departments

Recent Publications


Platelet and red cell responses to three North American pit vipers.

Journal Article Toxicon · August 28, 2024 We investigated the hemotoxic effects of three North American pit vipers in healthy human donor blood. Using experiments focusing on platelet and red blood cell activity, we found differential effects of these venoms on these cellular components. Platelet ... Full text Link to item Cite

Deciphering and disrupting PIEZO1-TMEM16F interplay in hereditary xerocytosis.

Journal Article Blood · January 25, 2024 Cell-surface exposure of phosphatidylserine (PS) is essential for phagocytic clearance and blood clotting. Although a calcium-activated phospholipid scramblase (CaPLSase) has longĀ been proposed to mediate PS exposure in red blood cells (RBCs), its identity ... Full text Link to item Cite

Clot Imaging Using Photostable Nanodiamond.

Journal Article Nanomaterials (Basel) · March 7, 2023 While thrombosis is the leading cause of morbidity and mortality in the United States, an understanding of its triggers, progression, and response to anticoagulant therapy is lacking. Intravital fluorescence microscopy has advanced the study of thrombus fo ... Full text Link to item Cite
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Recent Grants


An Examination of a Novel Fluorescence Assay in the Diagnosis of Heparin Induced Thrombocytopenia

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2022 - 2023

Platelet Kinetics in Acute Thrombus Formation in Healthy and VTE Patients

FellowshipPrincipal Investigator · Awarded by Society for Academic Emergency Medicine · 2019 - 2022

An examination of coagulation and inflammatory response of healthy donor whole blood to three North American snake venoms

ResearchPrincipal Investigator · Awarded by BTG International Inc · 2021 - 2022

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Education, Training & Certifications


Indiana University, School of Medicine · 2011 M.D.
University of Notre Dame · 2007 B.S.