Journal ArticleJ Am Heart Assoc · July 15, 2025
BACKGROUND: Use of CYP2C19 genotyping to guide antiplatelet therapy is associated with improved clinical outcomes in patients naïve to P2Y12 inhibitors undergoing percutaneous coronary intervention. The relationship between CYP2C19 genotype and clinical ou ...
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Journal ArticleJ Am Heart Assoc · June 18, 2024
BACKGROUND: Cytochrome P450 2C19 (CYP2C19) intermediate and poor metabolizer patients exhibit diminished clopidogrel clinical effectiveness after percutaneous coronary intervention (PCI). However, outcome studies to date have lacked racial diversity. Thus, ...
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Journal ArticleCatheter Cardiovasc Interv · May 1, 2020
BACKGROUND: Transcatheter mitral valve repair (TMVR) has shown to be a safe and effective treatment option for symptomatic severe mitral regurgitation (MR) in patients who are at prohibitive surgical risk. Whether age and comorbidities impact the inpatient ...
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Journal ArticleAm J Cardiol · August 1, 2018
Smoking is an important risk factor in the development of heart failure with preserved ejection (HFpEF), and previous reports have identified smoking as a significant predictor of death in this population. However, the relation between smoking and heart fa ...
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Journal ArticleHeart Rhythm · February 2018
BACKGROUND: Cardiovascular outcomes vary between urban and rural hospitals, with worse outcomes in rural settings. OBJECTIVE: The purpose of this study was to examine whether in-hospital mortality for hospitalization for atrial fibrillation (AF) varied bet ...
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Journal ArticleEur Heart J Cardiovasc Imaging · July 1, 2017
AIMS: To determine if markers of diastolic dysfunction are associated with atrial fibrillation (AF) development among patients with heart failure with preserved ejection fraction (HFpEF). METHODS AND RESULTS: We examined the association of several echocard ...
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Journal ArticleAm J Cardiol · June 1, 2017
Atrial fibrillation (AF) is associated with an increased risk for adverse events in patients with heart failure with preserved ejection fraction (HFpEF), but it is currently unknown if gender differences in these outcomes exist. To explore this hypothesis, ...
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Journal ArticleClin Cardiol · April 2017
BACKGROUND: The absence of abnormalities on noninvasive cardiac assessment possibly confers a reduced risk of atrial fibrillation (AF) despite the presence of traditional risk factors. HYPOTHESIS: Normal findings on noninvasive cardiac assessment are assoc ...
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Journal ArticleAm J Cardiol · March 15, 2017
The lack of abnormalities found on noninvasive cardiac testing possibly improves cardiovascular disease (CVD) risk stratification efforts and conveys reduced risk despite the presence of traditional risk factors. This analysis included 3,805 (95% white and ...
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Journal ArticleVasc Health Risk Manag · 2016
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice, and it places a substantial burden on the health care system. Despite improvements in our understanding of AF pathophysiology, we have yet to develop targete ...
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