https://orcid.org/0000-0001-9705-6390
Current Appointments & Affiliations
Associate Professor of Pharmacology and Cancer Biology
·
2024 - Present
Pharmacology & Cancer Biology,
Basic Science Departments
Associate Professor of Cell Biology
·
2024 - Present
Cell Biology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2015 - Present
Duke Cancer Institute,
Institutes and Centers
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Identification of New Ciliary Signaling Pathways in the Brain and Insights into Neurological Disorders.
Journal Article J Neurosci · August 13, 2025 Primary cilia are conserved sensory hubs essential for signaling transduction and embryonic development. Ciliary dysfunction causes a variety of developmental syndromes with neurological features and cognitive impairment whose basis mostly remains unknown. ... Full text Link to item CiteTTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins.
Journal Article Mol Biol Cell · January 1, 2023 The serine-threonine kinase tau tubulin kinase 2 (TTBK2) is a key regulator of the assembly of primary cilia, which are vital signaling organelles. TTBK2 is also implicated in the stability of the assembled cilium through mechanisms that remain to be defin ... Full text Link to item CiteMultiple ciliary localization signals control INPP5E ciliary targeting.
Journal Article Elife · September 5, 2022 Primary cilia are sensory membrane protrusions whose dysfunction causes ciliopathies. INPP5E is a ciliary phosphoinositide phosphatase mutated in ciliopathies like Joubert syndrome. INPP5E regulates numerous ciliary functions, but how it accumulates in cil ... Full text Link to item CiteRecent Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027View All Grants
Education
University of North Carolina, Chapel Hill ·
2007
Ph.D.
Macalester College ·
2001
B.A.