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Sarah Anne Kelleher

Assistant Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
Duke Psychiatry, DUMC Box #102506, Durham, NC 27710
2400 Pratt Street, North Pavilion, 7th Floor, Room 7045, Durham, NC 27705

Selected Publications


Improving multimodal physical function in adults with heterogeneous chronic pain; Protocol for a multisite feasibility RCT.

Journal Article Contemp Clin Trials · March 2024 BACKGROUND: Chronic pain is associated with substantial impairment in physical function, which has been identified as a top concern among persons with pain. GetActive-Fitbit, a mind-body activity program, is feasible, acceptable, and associated with improv ... Full text Link to item Cite

Meaning-centered pain coping skills training for patients with metastatic cancer: Protocol for a randomized controlled efficacy trial.

Journal Article Contemp Clin Trials · December 2023 BACKGROUND: Many patients with advanced cancer describe pain as a debilitating symptom that greatly interferes with daily activities and enjoyment of life. Psychosocial interventions can improve cancer-related pain but rarely address spiritual concerns (e. ... Full text Link to item Cite

Breast cancer survivors with pain: an examination of the relationships between body mass index, physical activity, and symptom burden.

Journal Article Support Care Cancer · October 2, 2023 PURPOSE: Overweight and obesity are common for breast cancer survivors and associated with high symptom burden (i.e., pain, fatigue, depressive symptoms). Physical activity may protect breast cancer survivors with higher body mass indexes (BMI) from increa ... Full text Link to item Cite

Behavioral cancer pain intervention dosing: results of a Sequential Multiple Assignment Randomized Trial.

Journal Article Pain · September 1, 2023 Behavioral pain management interventions are efficacious for reducing pain in patients with cancer. However, optimal dosing of behavioral pain interventions for pain reduction is unknown, and this hinders routine clinical use. A Sequential Multiple Assignm ... Full text Link to item Cite

Cost-Effectiveness Analysis Evaluating Delivery Strategies for Pain Coping Skills Training in Women With Breast Cancer.

Journal Article J Pain · September 2023 Pain coping skills training (PCST) is efficacious in patients with cancer, but clinical access is limited. To inform implementation, as a secondary outcome, we estimated the cost-effectiveness of 8 dosing strategies of PCST evaluated in a sequential multip ... Full text Link to item Cite

Effect of Pain Coping Skills Training on Pain and Pain Medication Use for Women With Breast Cancer.

Journal Article J Pain Symptom Manage · July 2023 CONTEXT: Pain is distressing for women with breast cancer. Pain medication may not provide full relief and can have negative side-effects. Cognitive-behavioral pain intervention protocols reduce pain severity and improve self-efficacy for pain management. ... Full text Link to item Cite

Meaning-centered pain coping skills training for patients with metastatic cancer: Results of a randomized controlled pilot trial.

Journal Article Psychooncology · July 2023 OBJECTIVE: For patients with advanced cancer, pain is a common and debilitating symptom that can negatively impact physical, emotional, and spiritual well-being. This trial examined the feasibility and initial effects of Meaning-Centered Pain Coping Skills ... Full text Link to item Cite

Feasibility of Mobile App-based Coping Skills Training for Cardiorespiratory Failure Survivors: The Blueprint Pilot Randomized Controlled Trial.

Journal Article Ann Am Thorac Soc · June 2023 Rationale: Psychological distress symptoms are common among patients recently hospitalized with cardiorespiratory failure, yet there are few effective postdischarge therapies that are relevant to their experiences. Objectives: To determine the feasibility ... Full text Link to item Cite

mHealth Coping Skills Training for Symptom Management (mCOPE) for colorectal cancer patients in early to mid-adulthood: Study protocol for a randomized controlled trial.

Journal Article Contemp Clin Trials Commun · June 2023 BACKGROUND: Colorectal cancer (CRC) patients in early to mid-adulthood (≤50 years) are challenged by high symptom burden (i.e., pain, fatigue, distress) and age-related stressors (e.g., managing family, work). Cognitive behavioral theory (CBT)-based coping ... Full text Link to item Cite

Role of self-efficacy for pain management and pain catastrophizing in the relationship between pain severity and depressive symptoms in women with breast cancer and pain.

Journal Article J Psychosoc Oncol · 2023 PURPOSE: This study evaluated the relationship between pain and depressive symptoms through pain self-efficacy and pain catastrophizing in breast cancer patients with pain. DESIGN: Secondary analysis of a randomized trial investigating a cognitive-behavior ... Full text Link to item Cite

Hybrid-delivered cognitive behavioral symptom management and activity coaching intervention for patients undergoing hematopoietic stem cell transplant: Findings from intervention development and a pilot randomized trial.

Journal Article J Psychosoc Oncol · 2023 OBJECTIVE: Develop and pilot test a mobile health (mHealth) cognitive behavioral coping skills training and activity coaching protocol (HCT Symptoms and Steps) for hematopoietic stem cell transplant (HCT) patients. DESIGN: Two-phase, mixed methods study. S ... Full text Link to item Cite

Virtual reality for improving pain and pain-related symptoms in patients with advanced stage colorectal cancer: A pilot trial to test feasibility and acceptability.

Journal Article Palliat Support Care · August 2022 OBJECTIVE: Virtual reality (VR) has the potential to improve pain and pain-related symptoms. We examined the feasibility, acceptability, safety, and impact of a 30-min virtual underwater/sea environment (VR Blue) for reducing pain and pain-related symptoms ... Full text Link to item Cite

Pain, depressive symptoms, and self-efficacy for pain management: examination in African-American women with breast cancer.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · August 2022 PurposeAfrican-American women with breast cancer face significant disparities, including high levels of pain. Depressive symptoms and self-efficacy for pain management impact how women with breast cancer manage pain, yet little is known about how ... Full text Cite

Geriatric Assessment Reveals Actionable Impairments in Hematopoietic Stem Cell Transplantation Candidates Age 18 to 80 Years.

Journal Article Transplant Cell Ther · August 2022 Allogeneic hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for both malignant and nonmalignant hematologic diseases; however, reported rates of treatment-related mortality approach 30%. Outcomes are worse in patients who b ... Full text Link to item Cite

Linking physical activity to personal values: feasibility and acceptability randomized pilot of a behavioral intervention for older adults with osteoarthritis pain.

Journal Article Pilot Feasibility Stud · August 1, 2022 BACKGROUND: Osteoarthritis (OA) pain is common and leads to functional impairment for many older adults. Physical activity can improve OA outcomes for older adults, but few are appropriately active. Behavioral interventions can reduce physical activity bar ... Full text Link to item Cite

Designing Psychosocial Intervention Pilot Studies: A Tutorial for Palliative Care Investigators.

Journal Article J Pain Symptom Manage · June 2022 This is a tutorial on designing a persuasive pilot study of a psychosocial intervention (e.g., behavioral symptom management) in the palliative care setting. This tutorial is most relevant for early stages of intervention research that aims to progress tow ... Full text Link to item Cite

Meaning-Centered Pain Coping Skills Training: A Pilot Feasibility Trial of a Psychosocial Pain Management Intervention for Patients with Advanced Cancer.

Journal Article J Palliat Med · January 2022 Background: Pain from advanced cancer can greatly reduce patients' physical, emotional, and spiritual well-being. Objective: To examine the feasibility and acceptability of a behavioral pain management intervention, Meaning-Centered Pain Coping Skills Trai ... Full text Link to item Cite

A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms.

Journal Article Contemp Clin Trials · November 2021 BACKGROUND/AIMS: Many cancer survivors who received intensive treatment such as hematopoietic stem cell transplantation (HCT) experience posttraumatic stress disorder (PTSD) symptoms. PTSD is associated with lower quality of life and other symptoms that re ... Full text Link to item Cite

Feasibility, engagement, and acceptability of a behavioral pain management intervention for colorectal cancer survivors with pain and psychological distress: data from a pilot randomized controlled trial.

Journal Article Support Care Cancer · September 2021 PURPOSE: Colorectal cancer survivors report pain and psychological distress to be burdensome long-term cancer consequences. Quality cancer survivorship care includes interventions for managing these symptoms. Yet, no studies have tested the efficacy of an ... Full text Link to item Cite

Relationship between social support, physical symptoms, and depression in women with breast cancer and pain.

Journal Article Support Care Cancer · September 2021 PURPOSE: Fatigue and pain are common among women with breast cancer, and often related to depressive symptoms. Social support may influence levels of fatigue, pain interference, and depressive symptoms. We tested a theory-based, structural model examining ... Full text Link to item Cite

Behavioral cancer pain intervention using videoconferencing and a mobile application for medically underserved patients: Rationale, design, and methods of a prospective multisite randomized controlled trial.

Journal Article Contemp Clin Trials · March 2021 BACKGROUND: Women with breast cancer in medically underserved areas are particularly vulnerable to persistent pain and disability. Behavioral pain interventions reduce pain and improve outcomes. Cancer patients in medically underserved areas receive limite ... Full text Link to item Cite

Persistent Breast Pain

Chapter · January 1, 2021 Persistent breast pain (PBP) following a cancer diagnosis and treatment is common and can be highly distressing, interfering with daily activities, and leading to decreases in overall quality of life. PBP can result from breast surgeries, radiation, chemot ... Full text Cite

Predictors of Intervention Session Completion in a Randomized Clinical Trial of a Behavioral Cancer Pain Intervention.

Journal Article J Pain Symptom Manage · June 2020 CONTEXT: Some patients with cancer are able to complete psychosocial pain management intervention sessions, and others find it difficult to do so. OBJECTIVES: Conduct a secondary analysis of a randomized clinical trial (N = 178) that compared delivery form ... Full text Link to item Cite

A behavioral cancer pain intervention: A randomized noninferiority trial comparing in-person with videoconference delivery.

Journal Article Psychooncology · August 2019 OBJECTIVE: Behavioral cancer pain interventions are efficacious for improving important pain outcomes; yet, traditional in-person delivery limits patient access. This study compared videoconference-delivered mobile health pain coping skills training (mPCST ... Full text Link to item Cite

Development and pilot testing of an mHealth behavioral cancer pain protocol for medically underserved communities.

Journal Article J Psychosoc Oncol · 2019 The purpose of this study was to refine and test a mobile-health behavioral cancer pain coping skills training protocol for women with breast cancer and pain from medically underserved areas. Three focus groups (Phase 1) were used to refine the initial pro ... Full text Link to item Cite

The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation.

Journal Article Support Care Cancer · April 2018 PURPOSE: Pain is common for hematopoietic stem cell transplant (HSCT) patients and may be experienced pre-transplant, acutely post-transplant, and for months or years following transplant. HSCT patients with persistent pain may be at risk for poor quality ... Full text Link to item Cite

An mHealth Pain Coping Skills Training Intervention for Hematopoietic Stem Cell Transplantation Patients: Development and Pilot Randomized Controlled Trial.

Journal Article JMIR Mhealth Uhealth · March 19, 2018 BACKGROUND: Pain is a challenge for patients following hematopoietic stem cell transplantation (HCT). OBJECTIVE: This study aimed to develop and test the feasibility, acceptability, and initial efficacy of a Web-based mobile pain coping skills training (mP ... Full text Link to item Cite

Effects of a Telephone- and Web-based Coping Skills Training Program Compared with an Education Program for Survivors of Critical Illness and Their Family Members. A Randomized Clinical Trial.

Journal Article Am J Respir Crit Care Med · January 1, 2018 RATIONALE: Many survivors of critical illness and their family members experience significant psychological distress after patient discharge. OBJECTIVES: To compare the effects of a coping skills training (CST) program with an education program on patient ... Full text Link to item Cite

Positive and negative mood following imaging-guided core needle breast biopsy and receipt of biopsy results.

Journal Article Psychol Health Med · December 2017 Positive and negative mood are independent psychological responses to stressful events. Negative mood negatively impacts well-being and co-occurring positive mood leads to improved adjustment. Women undergoing core needle breast biopsies (CNB) experience d ... Full text Link to item Cite

An mHealth Pain Coping Skills Training Intervention for Hematopoietic Stem Cell Transplantation Patients: Development and Pilot Randomized Controlled Trial (Preprint)

Journal Article · July 27, 2017 BACKGROUNDPain is a challenge for patients following hematopoietic stem cell transplantation (HCT). Full text Cite

Optimizing delivery of a behavioral pain intervention in cancer patients using a sequential multiple assignment randomized trial SMART.

Journal Article Contemp Clin Trials · June 2017 BACKGROUND/AIMS: Pain is common in cancer patients and results in lower quality of life, depression, poor physical functioning, financial difficulty, and decreased survival time. Behavioral pain interventions are effective and nonpharmacologic. Traditional ... Full text Link to item Cite

Cognitive problems following hematopoietic stem cell transplant: relationships with sleep, depression and fatigue.

Journal Article Bone Marrow Transplant · February 2017 Cognitive problems are a significant, persistent concern for patients undergoing hematopoietic stem cell transplant (HSCT). Sleep is important for many cognitive tasks; however, the relationship between sleep and cognitive problems for HSCT patients is unk ... Full text Link to item Cite

Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.

Journal Article PLoS One · 2017 OBJECTIVE: To determine whether a social cognitive theory (SCT)-based intervention improves resistance training (RT) maintenance and strength, and reduces prediabetes prevalence. RESEARCH DESIGN AND METHODS: Sedentary, overweight/obese (BMI: 25-39.9 kg/m2) ... Full text Link to item Cite

Using Patient Reported Outcomes in Oncology Clinical Practice.

Journal Article Scand J Pain · October 2016 BACKGROUND AND AIMS: Patient reported outcomes (PROs) are increasingly being implemented into the care of patients with cancer. The use of a standard set of PROs (e.g., pain) in cancer is becoming established and there is interest in what additional PROs m ... Full text Link to item Cite

A Small Randomized Controlled Pilot Trial Comparing Mobile and Traditional Pain Coping Skills Training Protocols for Cancer Patients with Pain.

Journal Article Pain Res Treat · 2016 Psychosocial pain management interventions are efficacious for cancer pain but are underutilized. Recent advances in mobile health (mHealth) technologies provide new opportunities to decrease barriers to access psychosocial pain management interventions. T ... Full text Link to item Cite

A Pilot Study of a Mobile Health Pain Coping Skills Training Protocol for Patients With Persistent Cancer Pain.

Journal Article J Pain Symptom Manage · October 2015 CONTEXT: Pain coping skills training (PCST) interventions have shown efficacy for reducing pain and providing other benefits in patients with cancer. However, their reach is often limited because of a variety of barriers (e.g., travel, physical burden, cos ... Full text Link to item Cite

Questionnaires for outcome expectancy, self-regulation, and behavioral expectation for resistance training among young-old adults: development and preliminary validity.

Journal Article J Aging Phys Act · April 2015 The purpose of the present research was to develop questionnaires to assess outcome expectancy for resistance training (RT), behavioral expectation in the context of perceived barriers to RT, and self-regulation strategies for RT among young-old adults (50 ... Full text Link to item Cite

TWO PHASES OF PILOTING A MHEALTH BEHAVIORAL INTERVENTION FOR CANCER PAIN

Journal Article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2015 Link to item Cite

SURVIVORSHIP CARE PLANS: INITIAL EVIDENCE OF POSITIVE IMPACT FOR CANCER SURVIVORS

Journal Article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2015 Link to item Cite

Randomized Noninferiority Trial of Telephone Versus In-Person Genetic Counseling for Hereditary Breast and Ovarian Cancer

Journal Article Journal of Clinical Oncology · March 1, 2014 Purpose Although guidelines recommend in-person counseling before BRCA1/BRCA2 gene testing, genetic counseling is increasingly offered by telephone. As genomic testing becomes more common, evaluating alternative d ... Full text Cite

Psychophysiological Reactivity to Abuse-Related Stimuli in Sexually Revictimized Women

Journal Article Journal of Aggression, Maltreatment & Trauma · October 2012 Full text Cite

Randomized trial of a decision aid for BRCA1/BRCA2 mutation carriers: impact on measures of decision making and satisfaction.

Journal Article Health Psychol · January 2009 OBJECTIVE: Genetic testing is increasingly part of routine clinical care for women with a family history of breast cancer. Given their substantially elevated risk for breast cancer, BRCA1/BRCA2 mutation carriers must make the difficult decision whether or ... Full text Link to item Cite