Sarah Peskoe

Journal Article Stat · September 1, 2024 The delivery of academic statistical collaboration resources can vary among types of institutions and across time. In particular, this variation might occur in the management of infrastructure and the business model, the staffing model and opportunities fo ... Full text Cite

Methods for building a staff workforce of quantitative scientists in academic health care.

Journal Article Stat (Int Stat Inst) · June 2024 Collaborative quantitative scientists, including biostatisticians, epidemiologists, bio-informaticists, and data-related professionals, play vital roles in research, from study design to data analysis and dissemination. It is imperative that academic healt ... Full text Link to item Cite

Health care resource utilization and clinical outcomes for adult heart transplant recipients with primary graft dysfunction.

Journal Article Clin Transplant · October 2023 INTRODUCTION: The advent of new technologies to reduce primary graft dysfunction (PGD) and improve outcomes after heart transplantation are costly. Adoption of these technologies requires a better understanding of health care utilization, specifically the ... Full text Link to item Cite

Validity of the Bern Score as a Surrogate Marker of Clinical Severity in Patients with Spontaneous Intracranial Hypotension.

Journal Article AJNR Am J Neuroradiol · September 2023 BACKGROUND AND PURPOSE: The Bern score is a quantitative scale characterizing brain MR imaging changes in spontaneous intracranial hypotension. Higher scores are associated with more abnormalities on brain MR imaging, raising the question of whether the sc ... Full text Link to item Cite

Does treatment at a level I trauma center reduce disparities in patient outcomes for open tibia fractures? A retrospective analysis of the National trauma Databank.

Journal Article J Clin Orthop Trauma · August 2023 BACKGROUND: Race and insurance status are independent predictors of healthcare outcomes following lower-extremity trauma. Level 1 trauma centers show better outcomes overall, but it is has not been extensively studied as to whether they specifically lower ... Full text Link to item Cite

Evaluation of Frailty Measures and Short-term Outcomes After Lung Transplantation.

Journal Article Chest · July 2023 BACKGROUND: Frailty, measured as a single construct, is associated variably with poor outcomes before and after lung transplantation. The usefulness of a comprehensive frailty assessment before transplantation is unknown. RESEARCH QUESTION: How are multipl ... Full text Link to item Cite

ESTIMATION AND INFERENCE FOR EXPOSURE EFFECTS WITH LATENCY IN THE COX PROPORTIONAL HAZARDS MODEL IN THE PRESENCE OF EXPOSURE MEASUREMENT ERROR

Journal Article Annals of Applied Statistics · June 1, 2023 Researchers are often interested in estimating the effects of time-varying exposures on health outcomes. The latency period, defined as the critical period of susceptibility, can be an important component of exposure effect as-sessment. Although it is wide ... Full text Cite

A comparison of deprivation indices and application to transplant populations.

Journal Article Am J Transplant · March 2023 The choice of deprivation index can influence conclusions drawn regarding the extent of deprivation within a community and the identification of the most deprived communities in the United States. This study aimed to determine the degree of correlation amo ... Full text Link to item Cite

Association of Perceived Neighborhood Health With Hypertension Self-care.

Journal Article JAMA Netw Open · February 1, 2023 IMPORTANCE: Hypertension self-management is recommended for optimal blood pressure (BP) control, but self-identified residential contextual factors that hinder hypertension self-care are understudied. OBJECTIVE: To quantify perceived neighborhood health an ... Full text Link to item Cite

Association of the Affordable Care Act on Access to and Outcomes After Kidney or Liver Transplant: A Transplant Registry Study.

Journal Article Transplant Proc · 2023 BACKGROUND: To evaluate the effect of the Affordable Care Act (ACA) Medicaid expansion on payor mix among patients on the kidney and liver transplant waiting list as well as waiting list and post-transplant outcomes. DESIGN: Using the Scientific Registry o ... Full text Link to item Cite

Experiential Learning Methods for Biostatistics Students: A Model for Embedding Student Interns in Academic Health Centers.

Journal Article Stat · December 2022 This manuscript describes an experiential learning program for future collaborative biostatisticians (CBs) developed within an academic medical center. The program is a collaborative effort between the Biostatistics, Epidemiology, and Research Design (BERD ... Full text Link to item Cite

Association between Gentrification and Health and Healthcare Utilization.

Journal Article J Urban Health · December 2022 There is tremendous interest in understanding how neighborhoods impact health by linking extant social and environmental drivers of health (SDOH) data with electronic health record (EHR) data. Studies quantifying such associations often use static neighbor ... Full text Link to item Cite

Screening for Eustachian Tube Dysfunction in Clinical Practice Using the Eustachian Tube Dysfunction Questionnaire-7.

Journal Article Laryngoscope · November 2022 OBJECTIVES/HYPOTHESIS: To evaluate the ability of the Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) to discriminate between patients with Eustachian tube dysfunction (ETD) and Non-ETD diagnoses, and identify symptom information to improve ability to ... Full text Link to item Cite

Decisional Conflict About Kidney Failure Treatment Modalities Among Adults With Advanced CKD.

Journal Article Kidney Med · September 2022 RATIONALE & OBJECTIVE: Choosing from multiple kidney failure treatment modalities can create decisional conflict, but little is known about this experience before decision implementation. We explored decisional conflict about treatment for kidney failure a ... Full text Link to item Cite

Geospatial Analysis of Organ Transplant Referral Regions.

Journal Article JAMA Netw Open · September 1, 2022 IMPORTANCE: System and center-level interventions to improve health equity in organ transplantation benefit from robust characterization of the referral population served by each transplant center. Transplant referral regions (TRRs) define geographic catch ... Full text Link to item Cite

Disparities in Discussions about Kidney Replacement Therapy in CKD Care.

Journal Article Kidney360 · January 27, 2022 Participants who identified as female and Black reported more thorough discussions of dialysis than transplant.Participants with low incomes and education reported more thorough discussions of dialysis than transplant. ... Full text Link to item Cite

The Association Between Hearing Loss and Surgical Complications in Older Adults.

Journal Article Ear Hear · 2022 OBJECTIVES: In this study, we sought to evaluate whether older patients with hearing loss who underwent surgery were at greater risk of postsurgical complications, increased inpatient length-of-stay (LOS), and hospital readmission. DESIGN: This was a retro ... Full text Link to item Cite

Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.

Journal Article BMC Nephrol · November 11, 2021 BACKGROUND: Individuals with chronic kidney disease (CKD), hypertension (HTN), or diabetes mellitus (DM) are at increased risk for cardiovascular disease (CVD). The extent to which psychosocial factors are associated with increased CVD risk within these in ... Full text Link to item Cite

Adjusting for selection bias due to missing data in electronic health records-based research.

Journal Article Stat Methods Med Res · October 2021 While electronic health records data provide unique opportunities for research, numerous methodological issues must be considered. Among these, selection bias due to incomplete/missing data has received far less attention than other issues. Unfortunately, ... Full text Link to item Cite

Loss to follow up of failed hearing screen and missed opportunities to detect congenital cytomegalovirus are better identified with the implementation of a new electronic health record system protocol.

Journal Article Int J Pediatr Otorhinolaryngol · September 2021 INTRODUCTION: Congenital CMV (cCMV) is the leading cause of non-genetic sensorineural hearing loss. Babies with cCMV can present with hearing loss any time but failing the initial hearing screen should trigger cCMV testing. cCMV must be identified within 3 ... Full text Link to item Cite

Preliminary Evidence on the Impact of Hearing Aid Use on Falls Risk in Individuals With Self-Reported Hearing Loss.

Journal Article Am J Audiol · June 14, 2021 Purpose Falls are considered a significant public health issue, and hearing loss has been shown to be an independent risk factor for falls. The primary objective of this study was to determine if hearing aid use modified (reduced) the association. We hypot ... Full text Link to item Cite

Quantified electronic health record (EHR) use by academic surgeons.

Journal Article Surgery · June 2021 BACKGROUND: The electronic health record has improved medical billing, research, and sharing of patient data, but its clinical use by physicians has been linked to rising physician burnout leading to numerous subjective editorials about the electronic heal ... Full text Link to item Cite

Targeting Patient and Health System Barriers To Improve Rates of Hemodialysis Initiation with an Arteriovenous Access.

Journal Article Kidney360 · April 29, 2021 BACKGROUND: Guidelines recommend pre-emptive creation of arteriovenous (AV) access. However, <20% of US patients initiate hemodialysis (HD) with a functional AV access. We implemented a quality improvement (QI) program to improve pre-HD vascular access car ... Full text Link to item Cite

African Americans' discussions about living-donor kidney transplants with family or friends: Who, what, and why not?

Journal Article Clin Transplant · April 2021 BACKGROUND: Although discussions with family or friends can improve access to living-donor kidney transplantation (LDKT), they remain an understudied step in the LDKT process. METHODS: Among 300 African American transplant candidates, we examined how socio ... Full text Link to item Cite

A three-tier system for evaluation of organ procurement organizations' willingness to pursue and utilize nonideal donor lungs.

Journal Article Am J Transplant · March 2021 Lungs from "nonideal," but acceptable donors are underutilized; however, organ procurement organization (OPO) metrics do not reflect the extent to which OPO-specific practices contribute to these trends. We developed a comprehensive system to evaluate noni ... Full text Link to item Cite

Exploring Factors Associated With Morbidity and Mortality in Patients With Do-Not-Resuscitate Orders: A National Surgical Quality Improvement Program Database Analysis Within Surgical Groups.

Journal Article Anesth Analg · February 1, 2021 BACKGROUND: Anesthesiologists caring for patients with do-not-resuscitate (DNR) orders may have ethical concerns because of their resuscitative wishes and may have clinical concerns because of their known increased risk of morbidity/mortality. Patient hete ... Full text Link to item Cite

Integrated Digital Health System Tools to Support Decision Making and Treatment Preparation in CKD: The PREPARE NOW Study.

Journal Article Kidney Med · 2021 RATIONALE & OBJECTIVE: Digital health system tools to support shared decision making and preparation for kidney replacement treatments for patients with chronic kidney disease (CKD) are needed. STUDY DESIGN: Descriptive study of the implementation of digit ... Full text Link to item Cite

Preferences for and Experiences of Shared and Informed Decision Making Among Patients Choosing Kidney Replacement Therapies in Nephrology Care.

Journal Article Kidney Med · 2021 RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) can progress rapidly, and patients are often unprepared to make kidney failure treatment decisions. We aimed to better understand patients' preferences for and experiences of shared and informed decision ... Full text Link to item Cite

Methods for training collaborative biostatisticians.

Journal Article J Clin Transl Sci · August 4, 2020 The emphasis on team science in clinical and translational research increases the importance of collaborative biostatisticians (CBs) in healthcare. Adequate training and development of CBs ensure appropriate conduct of robust and meaningful research and, t ... Full text Link to item Cite

Depression and Functional Outcomes in Patients Presenting to the Emergency Department With Low Back Pain.

Journal Article Acad Emerg Med · August 2020 OBJECTIVES: Low back pain (LBP) is a common reason for patients to present to emergency departments (EDs). Our objective was to describe the associations between depressive symptoms, pain severity, and functional impairment up to 3 months after initial ED ... Full text Link to item Cite

Clinician adherence to the clinical practice guideline: Acute otitis externa.

Journal Article Laryngoscope · June 2020 OBJECTIVES/HYPOTHESIS: Over 10 years have passed since the Clinical Practice Guideline: Acute Otitis Externa (CPG-AOE) was first published, and it has been several years since its update. We sought to assess clinicians' adherence as well as referral patter ... Full text Link to item Cite

Associations of perceived information adequacy and knowledge with pursuit of live donor kidney transplants and living donor inquiries among African American transplant candidates.

Journal Article Clin Transplant · March 2020 We studied associations between perceived adequacy of live donor kidney transplant (LDKT) information or knowledge with pursuit of LDKT or receipt of live donor inquiries among 300 African American kidney transplant candidates. Participants reported via qu ... Full text Link to item Cite

Associations of Vestibular Tests With Penn Acoustic Neuroma Quality of Life Scores After Resection of Vestibular Schwannoma.

Journal Article Otol Neurotol · February 2020 OBJECTIVE: Determine associations between preoperative caloric testing and video head impulse testing (vHIT) with baseline and postoperative Penn Acoustic Neuroma Quality of Life (PANQOL) scores following resection of vestibular schwannoma (VS). STUDY DESI ... Full text Link to item Cite

Advanced CKD Care and Decision Making: Which Health Care Professionals Do Patients Rely on for CKD Treatment and Advice?

Journal Article Kidney Med · 2020 RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) care is often fragmented across multiple health care providers. It is unclear whether patients rely mostly on their nephrologists or non-nephrologist providers for medical care, including CKD treatment an ... Full text Link to item Cite

How and when informative visit processes can bias inference when using electronic health records data for clinical research.

Journal Article J Am Med Inform Assoc · December 1, 2019 OBJECTIVE: Electronic health records (EHR) data have become a central data source for clinical research. One concern for using EHR data is that the process through which individuals engage with the health system, and find themselves within EHR data, can be ... Full text Link to item Cite

Associations of Video Head Impulse Test and Caloric Testing among Patients with Vestibular Schwannoma.

Journal Article Otolaryngol Head Neck Surg · August 2019 OBJECTIVE: To determine relationships between caloric testing (CT) and video head impulse testing (vHIT) among patients with unilateral vestibular schwannoma (VS). To describe the distribution of CT and vHIT measurements and assess associations with tumor ... Full text Link to item Cite

Validation of the American College of Surgeons National Surgical Quality Improvement Program Risk Model for Patients Undergoing Panniculectomy.

Journal Article Ann Plast Surg · July 2019 UNLABELLED: Panniculectomy procedures have been reported to significantly improve quality of life, increase mobility, and improve hygiene in patients with a significant pannus formation. The primary aims of this study were to determine which preoperative r ... Full text Link to item Cite

The Impact of Ergonomics on Recruitment to Surgical Fields: A Multi-Institutional Survey Study.

Journal Article J Surg Res · April 2019 BACKGROUND: Awareness of ergonomics in surgery is growing, but whether musculoskeletal (MSK) injuries in surgery influence trainee career choices remains unknown. This study aimed to characterize medical students' MSK pain during surgical rotations and det ... Full text Link to item Cite

There is no impact of exposure measurement error on latency estimation in linear models.

Journal Article Stat Med · March 30, 2019 Identification of the latency period for the effect of a time-varying exposure is key when assessing many environmental, nutritional, and behavioral risk factors. A pre-specified exposure metric involving an unknown latency parameter is often used in the s ... Full text Link to item Cite

Identifying Predictors of Time to Soft-Tissue Reconstruction following Open Tibia Fractures.

Journal Article Plast Reconstr Surg · December 2018 BACKGROUND: Controversy remains regarding the optimal timing of soft-tissue coverage following severe lower extremity trauma. This study identifies nationwide practice patterns and factors associated with discrepancies in time to first flap surgery followi ... Full text Link to item Cite

Children with appendicitis on the US-Mexico border have socioeconomic challenges and are best served by a freestanding children's hospital.

Journal Article Pediatr Surg Int · December 2018 INTRODUCTION: The US-Mexico border is medically underserved. Recent political changes may render this population even more vulnerable. We hypothesized that children on the border present with high rates of perforated appendicitis due to socioeconomic barri ... Full text Link to item Cite

Documenting or Operating: Where Is Time Spent in General Surgery Residency?

Journal Article J Surg Educ · November 2018 OBJECTIVE: The utilization of electronic health records (EHR) has become essential in the daily activities of physicians for documentation and as an information source. However, the amount of time spent by residents utilizing the EHR has not been thoroughl ... Full text Link to item Cite

The effect of risk factor misclassification on the partial population attributable risk.

Journal Article Stat Med · April 15, 2018 The partial population attributable risk (pPAR) is used to quantify the population-level impact of preventive interventions in a multifactorial disease setting. In this paper, we consider the effect of nondifferential risk factor misclassification on the d ... Full text Link to item Cite

Prevalence estimation when disease status is verified only among test positives: Applications in HIV screening programs.

Journal Article Stat Med · March 30, 2018 The first goal of the United Nations' 90-90-90 HIV/AIDS elimination strategy is to ensure that, by 2020, 90% of HIV-positive people know their HIV status. Estimating the prevalence of HIV among people eligible for screening allows assessment of the number ... Full text Link to item Cite

A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.

Journal Article Cancer Epidemiol Biomarkers Prev · November 2014 BACKGROUND: TH1 cytokines, such as IFNγ and TNFα, and potentially innate cytokines, such as IL6, can potentiate the immune response to tumor. Cytokines, such as IL1β, IL8, and IL10, may suppress anticancer immunity. Thus, we prospectively evaluated the ass ... Full text Link to item Cite

Serum prostate-specific antigen (PSA) concentration is positively associated with rate of disease reclassification on subsequent active surveillance prostate biopsy in men with low PSA density.

Journal Article BJU Int · April 2014 OBJECTIVE: To investigate the association between serum prostate-specific antigen (PSA) concentration at active surveillance (AS) entry and disease reclassification on subsequent AS biopsy ('biopsy reclassification') in men with low PSA density (PSAD). To ... Full text Link to item Cite