Scholars@Duke
Sargam Kapoor

Sargam Kapoor

Assistant Professor of Medicine
Medicine, Hematology

Selected Publications

Surprise diagnosis of acquired von Willebrand syndrome in a patient previously thought to have type III von Willebrand disease: evaluation and periprocedural management.

Journal Article BMJ Case Rep · December 6, 2023 Acquired von Willebrand syndrome (AVWS) is a rare disorder that is characterised by an acquired deficiency of von Willebrand factor. AVWS was suspected in a patient with type III von Willebrand disease (VWD) who did not respond to factor replacement therap ... Full text Link to item Cite

Thrombotic microangiopathies: An illustrated review

Journal Article Research and Practice in Thrombosis and Haemostasis · March 1, 2022 The thrombotic microangiopathies (TMAs) are a heterogenous group of disorders with distinct pathophysiologies that cause occlusive microvascular or macrovascular thrombosis, and are characterized by microangiopathic hemolytic anemia, thrombocytopenia, and/ ... Full text Cite

The hypercoagulable state in COVID-19: Incidence, pathophysiology, and management.

Journal Article Thromb Res · October 2020 The 2019 coronavirus disease (COVID-19) presents with a large variety of clinical manifestations ranging from asymptomatic carrier state to severe respiratory distress, multiple organ dysfunction and death. While it was initially considered primarily a res ... Full text Link to item Cite

Priapism, hemoglobin desaturation, and red blood cell adhesion in men with sickle cell anemia.

Journal Article Blood Cells Mol Dis · November 2019 Priapism is a serious, but episodic, complication of sickle cell disease (SCD). We had previously reported that subjects with SCD had variable red blood cell (RBC) adhesion to the immobilized sub-endothelial protein laminin (LN). We examined adhesion to LN ... Full text Link to item Cite

Contribution of platelets, the coagulation and fibrinolytic systems to cutaneous wound healing.

Journal Article Thromb Res · July 2019 Wound healing is a complex process that consists of multiple phases, each of which are indispensable for adequate repair. Timely initiation and resolution of each of these phases namely, hemostasis, inflammation, proliferation and tissue remodeling, is cri ... Full text Link to item Cite

Advances in the Treatment of Sickle Cell Disease.

Journal Article Mayo Clin Proc · December 2018 Sickle cell disease (SCD) is a monogenic disorder that afflicts approximately 100,000 Americans and millions of people worldwide. It is characterized by hemolytic anemia, vaso-occlusive crises, relentless end-organ injury, and premature death. Currently, r ... Full text Link to item Cite

The role of neutrophils in thrombosis.

Journal Article Thromb Res · October 2018 Despite significant evidence implicating an important role for neutrophils in thrombosis, their impact on the thrombotic process has remained a matter of controversy. Until 2010, platelets, coagulation factors, fibrinogen and monocytes were implicated in t ... Full text Link to item Cite

Unusual Paraneoplastic Presentation of Cholangiocarcinoma

Journal Article Case Reports in Medicine · January 1, 2015 Introduction. Cutaneous paraneoplastic syndromes are a heterogeneous group of skin manifestations that occur in relation to many known malignancies. Paraneoplastic occurrence of SCLE has been noted but is not commonly reported. SCLE association with cholan ... Full text Cite