Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Oklahoma State University, Stillwater 2012
  • D.V.M., N.T.R. College of Veterinary Science, Gannavaram (India) 2005
• 

  Previous Appointments & Affiliations

  • Assistant Professor in Anesthesiology, Anesthesiology, Clinical Science Departments 2018 - 2020
• Research
• 

  Selected Grants

  • Pulmonary cell fate and lung repair in rodent and porcine models of chlorine and phosgene inhalation injuries awarded by National Institutes of Health 2022 - 2025
  • Inhibition of soluble epoxide hydrolase protects against phosgene-induced lung injuries awarded by National Institutes of Health 2021 - 2023
  • Intraganglionic Analgesic Adeno-Associated Virus (AAV) Gene Vector Optimization in Large Animals awarded by Interventional AnalgesiX, Inc. 2020 - 2023
  • An acute porcine model for Cardiac-Synchronized Diaphragmatic Stimulation as a novel extra-cardiac intervention for symptomatic chronic heart failure awarded by VisCardia, Inc. 2022 - 2023
  • Specialized pro-resolving mediators as potential medical countermeasures in a pig model of chlorine gas-induced acute lung injury awarded by National Institutes of Health 2020 - 2023
  • Biomarkers of lung injury in methyl isocyanate exposed rodents and pigs awarded by University of Colorado - Denver 2016 - 2021
  • RAPID Inexpensive, rapidly manufacturable respiratory monitor to provide safe emergency ventilation during COVID19 pandemic awarded by Convergent Engineering 2021
  • Mechanisms of Itch in Poison Ivy-Induced Allergic Contact Dermatitis awarded by National Institutes of Health 2016 - 2018
  • Targeting Injury Pathways to Counteract Pulmonary Agent and Vesicant Toxicity awarded by National Institutes of Health 2014 - 2018
  • Development of therapeutics for chlorine-induced airway and lung injury awarded by National Institutes of Health 2008 - 2018
  • Accelerating Inflammation Resolution to Counteract Chemical Injury awarded by National Institutes of Health 2012 - 2015
• 

  External Relationships

  • Humacyte
  • Maynard Animal Hospital and Urgent Care
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Marcus, Alan David, Satyanarayana Achanta, and Sven-Eric Jordt. “Protocol for non-invasive assessment of spontaneous movements of group-housed animals using remote video monitoring.” Star Protoc 3, no. 2 (June 17, 2022): 101326. https://doi.org/10.1016/j.xpro.2022.101326.
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    • Achanta, Satyanarayana, and Sven-Eric Jordt. “Toxic effects of chlorine gas and potential treatments: a literature review.” Toxicol Mech Methods 31, no. 4 (May 2021): 244–56. https://doi.org/10.1080/15376516.2019.1669244.
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    • Achanta, Satyanarayana, and Sven-Eric Jordt. “Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets.” Ann N Y Acad Sci 1480, no. 1 (November 2020): 73–103. https://doi.org/10.1111/nyas.14472.
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    • Achanta, Satyanarayana, Narendranath Reddy Chintagari, Marian Brackmann, Shrilatha Balakrishna, and Sven-Eric Jordt. “TRPA1 and CGRP antagonists counteract vesicant-induced skin injury and inflammation.” Toxicol Lett 293 (September 1, 2018): 140–48. https://doi.org/10.1016/j.toxlet.2018.03.007.
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    • Achanta, Satyanarayana, and Sven-Eric Jordt. “TRPA1: Acrolein meets its target.” Toxicol Appl Pharmacol 324 (June 1, 2017): 45–50. https://doi.org/10.1016/j.taap.2017.03.007.
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    • Caceres, Ana I., Boyi Liu, Sairam V. Jabba, Satyanarayana Achanta, John B. Morris, and Sven-Eric Jordt. “Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti-inflammatory effects of eucalyptol.” Br J Pharmacol 174, no. 9 (May 2017): 867–79. https://doi.org/10.1111/bph.13760.
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    • Prasad, V Gangadhara N. V., Satyanarayana Achanta, Yathiraja Rao Tammineni, Gopala Reddy Alla, Madhava Rao Thirtham, and G. S. Rao. “Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.” Eur J Drug Metab Pharmacokinet 41, no. 6 (December 2016): 733–41. https://doi.org/10.1007/s13318-015-0302-5.
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    • Liu, Boyi, Yan Tai, Satyanarayana Achanta, Melanie M. Kaelberer, Ana I. Caceres, Xiaomei Shao, Jianqiao Fang, and Sven-Eric Jordt. “IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.” Proc Natl Acad Sci U S A 113, no. 47 (November 22, 2016): E7572–79. https://doi.org/10.1073/pnas.1606608113.
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    • Rothenberg, Craig, Satyanarayana Achanta, Erik R. Svendsen, and Sven-Eric Jordt. “Tear gas: an epidemiological and mechanistic reassessment.” Annals of the New York Academy of Sciences 1378, no. 1 (August 2016): 96–107. https://doi.org/10.1111/nyas.13141.
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    • Achanta, S., A. Sewell, J. W. Ritchey, K. Broaddus, D. W. A. Bourne, C. R. Clarke, and L. K. Maxwell. “Anatomical and physiological basis for the allometric scaling of cisplatin clearance in dogs.” J Vet Pharmacol Ther 39, no. 3 (June 2016): 224–36. https://doi.org/10.1111/jvp.12266.
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    • Achanta, S., and L. K. Maxwell. “Reaction phenotyping of vinblastine metabolism in dogs.” Vet Comp Oncol 14, no. 2 (June 2016): 161–69. https://doi.org/10.1111/vco.12084.
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    • Liu, Boyi, Yan Tai, Ana I. Caceres, Satyanarayana Achanta, Shrilatha Balakrishna, Xiaomei Shao, Junfan Fang, and Sven-Eric Jordt. “Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice.” Plos One 11, no. 11 (2016): e0165200. https://doi.org/10.1371/journal.pone.0165200.
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    • Maxwell, Lara K., Penny Regier, and Satyanarayana Achanta. “Comparison of Glucosamine Absorption After Administration of Oral Liquid, Chewable, and Tablet Formulations to Dogs.” J Am Anim Hosp Assoc 52, no. 2 (2016): 90–94. https://doi.org/10.5326/JAAHA-MS-6267.
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    • Balakrishna, Shrilatha, Weifeng Song, Satyanarayana Achanta, Stephen F. Doran, Boyi Liu, Melanie M. Kaelberer, Zhihong Yu, et al. “TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.” Am J Physiol Lung Cell Mol Physiol 307, no. 2 (July 15, 2014): L158–72. https://doi.org/10.1152/ajplung.00065.2014.
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    • Achanta, Satyanarayana, Minh Ngo, Allison Veitenheimer, Lara K. Maxwell, and Jarrad R. Wagner. “Simultaneous quantification of vinblastine and desacetylvinblastine concentrations in canine plasma and urine samples using LC-APCI-MS/MS.” J Chromatogr B Analyt Technol Biomed Life Sci 913–914 (January 15, 2013): 147–54. https://doi.org/10.1016/j.jchromb.2012.11.012.
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  • Preprints

    • Achanta, Satyanarayana, Michael Gentile, Carolyn Albert, Kevin Schulte, Brooke Pantazides, Brian Crow, Jennifer Quiñones-González, et al. “Recapitulation of Human Pathophysiology and Identification of Forensic Biomarkers in a Translational Swine Model of Chlorine Inhalation Injury.” BioRxiv, 2022. https://doi.org/10.1101/2022.02.09.479576.
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    • Achanta, Satyanarayana, Narendranath Reddy Chintagari, Shrilatha Balakrishna, Boyi Liu, and Sven-Eric Jordt. “Accelerating Inflammation Resolution to Counteract Chemical Cutaneous Injury.” BioRxiv, 2019. https://doi.org/10.1101/749184.
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• Teaching & Mentoring
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  Teaching Activities

  • 2013 – 2014     Lecturer, The Pharmacological Basis of Therapeutics (CSY290a)
                            Yale University, New Haven, CT

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