Scott William Cousins
Robert Machemer, M.D. Distinguished Professor of Ophthalmology
Scott W. Cousins, M.D. is currently the Robert Machemer, M.D. Professor of Ophthalmology and Immunology, Vice Chair for Research, and Director of the Duke Center for Macular Diseases at Duke Eye Center. As Vice Chair, he oversees all basic science research as well as the Ophthalmology Site-Based Research Group, which administrates clinical research for Duke Eye Center. Dr. Cousins is also Medical Director of Hospital-Based Imaging and Procedures for Duke Eye Center.
Dr. Cousins is a retina-trained ophthalmologist who specializes in the diagnosis and treatment of macular diseases, especially age-related macular degeneration (AMD), diabetic retinopathy, and retinal vascular diseases. Dr. Cousins is active in both clinical and laboratory research. In his clinical practice, Dr. Cousins is involved in many trials and innovative therapies for the treatment of macular diseases, especially AMD and diabetic retinopathy. He has served as site PI for numerous phase1-3 clinical trials in AMD, diabetic retinopathy, and other retinal disorders. He has served as a consultant or member of data safety monitoring committees (DSMC) for numerous pharmaceutical and biotechnology startup companies.
In his scientific laboratory, Dr. Cousins pursues both NIH-funded and industry-funded research in various areas of dry and wet AMD. In particular, he is studying the role of circulating bone marrow-derived progenitors (stem cells) in contributing to wet AMD. His laboratory is attempting to develop treatments for dry macular degeneration and improving vision in eyes with wet macular degeneration. His program is also developing blood tests and new imaging technologies for the identification of patients who are at high risk for progressing into complications.
Dr. Cousins has published over 100 peer-reviewed manuscripts, book chapters, and other publications addressing topics of research or clinical care of retinal disease, especially AMD. In 2006, Dr. Cousins was awarded the prestigious Alcon Research Foundation Clinician Scientist Award. In 2008, the National Institutes of Health invited Dr. Cousins to join the National Advisory Eye Council. Dr. Cousins is also a member of the American Academy of Ophthalmology, the American Society of Retina Specialists, the Retina Society, the Association for Research in Vision and Ophthalmology, the American Association of Immunologists, and the American Medical Association.
In 2010, Dr. Cousins was named one of the “Top 34 Ophthalmologists in the United States” by Becker’s ASC Review, a leading source of business and legal news for ambulatory surgery centers. They cited his leadership of the Duke Center for Macular Diseases and his ongoing research in macular degeneration as reasons for the honor.
Dr. Cousins is a retina-trained ophthalmologist who specializes in the diagnosis and treatment of macular diseases, especially age-related macular degeneration (AMD), diabetic retinopathy, and retinal vascular diseases. Dr. Cousins is active in both clinical and laboratory research. In his clinical practice, Dr. Cousins is involved in many trials and innovative therapies for the treatment of macular diseases, especially AMD and diabetic retinopathy. He has served as site PI for numerous phase1-3 clinical trials in AMD, diabetic retinopathy, and other retinal disorders. He has served as a consultant or member of data safety monitoring committees (DSMC) for numerous pharmaceutical and biotechnology startup companies.
In his scientific laboratory, Dr. Cousins pursues both NIH-funded and industry-funded research in various areas of dry and wet AMD. In particular, he is studying the role of circulating bone marrow-derived progenitors (stem cells) in contributing to wet AMD. His laboratory is attempting to develop treatments for dry macular degeneration and improving vision in eyes with wet macular degeneration. His program is also developing blood tests and new imaging technologies for the identification of patients who are at high risk for progressing into complications.
Dr. Cousins has published over 100 peer-reviewed manuscripts, book chapters, and other publications addressing topics of research or clinical care of retinal disease, especially AMD. In 2006, Dr. Cousins was awarded the prestigious Alcon Research Foundation Clinician Scientist Award. In 2008, the National Institutes of Health invited Dr. Cousins to join the National Advisory Eye Council. Dr. Cousins is also a member of the American Academy of Ophthalmology, the American Society of Retina Specialists, the Retina Society, the Association for Research in Vision and Ophthalmology, the American Association of Immunologists, and the American Medical Association.
In 2010, Dr. Cousins was named one of the “Top 34 Ophthalmologists in the United States” by Becker’s ASC Review, a leading source of business and legal news for ambulatory surgery centers. They cited his leadership of the Duke Center for Macular Diseases and his ongoing research in macular degeneration as reasons for the honor.
Current Appointments & Affiliations
- Robert Machemer, M.D. Distinguished Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2006
- Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2005
- Vice-Chair, Strategic Planning, Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2020
- Professor in the Department of Immunology, Immunology, Basic Science Departments 2006
Contact Information
- Box 3802 Med Ctr, Durham, NC 27710
- Wadsworth Building, Durham, NC 27710
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scott.cousins@duke.edu
(919) 684-3090
- Background
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Education, Training, & Certifications
- Postdoctoral fellow, Microbiology And Immunology, University of Miami 1988 - 1990
- Research Fellow, Ophthalmology, University of Miami 1988 - 1989
- Instructor and Chief Resident, Ophthalmology, Washington University in St. Louis 1987 - 1988
- Clinical Fellow, Ophthalmology, University of Miami 1986 - 1987
- Resident, Ophthalmology, Washington University in St. Louis 1983 - 1986
- Intern, Internal Medicine, Case Western Reserve University 1982 - 1983
- Predoctoral Research Fellow, Ophthalmology And Immunology, Stanford University 1980 - 1982
- M.D., Case Western Reserve University 1982
- B.A., Dartmouth College 1977
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Previous Appointments & Affiliations
- Vice-Chair, Research, Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2009 - 2019
- Instructor, Temporary of Ophthalmology, Ophthalmology, Clinical Science Departments 2005
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Leadership & Clinical Positions at Duke
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Vice Chair for Research
Medical Director, Duke Eye Center On-Campus Clinical Practice
Medical Director, Duke Eye Center (hospital-based) Imaging and Procedures Unit
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Academic Positions Outside Duke
- Professor, University of Miami. 2002 - 2005
- Director of Research, University of Miami. 2000 - 2005
- Deputy Director Vascular Biology Inst, University of Miami. 1999 - 2005
- Associate Professor, University of Miami. 1995 - 2002
- Assistant Professor, University of Miami. 1990 - 1995
- Recognition
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In the News
- Research
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Selected Grants
- Role of Proteasome Overload in Pathogenesis of Retinitis Pigmentosa awarded by National Institutes of Health 2022 - 2027
- Role of Tissue Resident Macrophages in the Conventional Outflow Function awarded by National Institutes of Health 2021 - 2025
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
- In Vivo Modeling of Mitochondrial Complex I Deficiency in Retinal Ganglion Cells awarded by National Institutes of Health 2018 - 2023
- Prospective, Open-Label, Interventional, Single-Center Investigator- Initiated Trial of Combination ICG-Directed Visudyne (verteporfin) Photodynamic Therapy (PDT) and Intravitreal Lucentis (ranibizumab) for Trmt of patients with Neovascular AMD. awarded by Bausch & Lomb Incorporated 2014 - 2022
- An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects with Intermediate Age-Related Macular Degeneration awarded by Stealth BioTherapeutics 2016 - 2021
- A Deep Learning Model to Objectively Quantify Glaucomatous Damage on Fundus Photographs: Validation and Application to a Teleophthalmology Screening Program awarded by National Institutes of Health 2020 - 2021
- Muller glial dysfunction in retinal edema awarded by National Institutes of Health 2016 - 2020
- Study evaluating the safety and clinical response of sub-retinal administration of CNTO 2476 in subjects with visual acuity impairment associated with Geographic Atrophy Secondary to Age Related Macular Degeneration awarded by Janssen Research & Development, LLC 2016 - 2020
- Monocytes in Dry Age-Related Macular Degeneration awarded by National Institutes of Health 2016 - 2019
- Cognitive Changes and Brain Connectivity in Age-Related Macular Degeneration awarded by National Institutes of Health 2013 - 2019
- Macrophages and Treatment-Resistant NVAMD awarded by National Institutes of Health 2015 - 2019
- A randomized, double-masked, active-controlled Phase 2 study of the efficacy, safety, and tolerability of repeated doses of intravitreal REGN910-3 in patients with neovascular age-related macular degeneration. awarded by Regeneron Pharmaceuticals, Inc. 2017 - 2019
- River Vision RV001 awarded by River Vision Development Corporation 2014 - 2019
- A Phase I Open-Label, Dose-Escalating, Multi-Center Trial to Evaluate the Safety and Tolerability of Topical Ocular PAN-90806 in Patients with Neovascular Age-Related Macular Degeneration (AMD) awarded by PanOptica 2014 - 2019
- Flavoprotein Autofluorescence Imaging in AMD awarded by National Institutes of Health 2015 - 2018
- Mitochondrial Dysfunction in a New Model of Dry AMD awarded by National Institutes of Health 2016 - 2018
- Computer Aided Classification of Diabetic Macular Edema awarded by National Institutes of Health 2012 - 2018
- Lipid Activated Nuclear Receptors in Age-Related Macular Degeneration awarded by National Institutes of Health 2011 - 2017
- Macrophages Drive Neovascular Remodeling in NVAMD awarded by BrightFocus Foundation 2014 - 2016
- NEI Mentored Clinical Scientist Development Program Award (K12) awarded by National Institutes of Health 2004 - 2016
- Novel Retinal Biomarkers for Early Detection of Alzheimer's Disease awarded by Alzheimer's Association 2013 - 2016
- Negative regulation of NF-kB by optineurin in primary open angle glaucoma awarded by National Institutes of Health 2011 - 2014
- Vascular Progenitor Cells in Neovascular AMD awarded by National Institutes of Health 2008 - 2014
- Developing Interventions to Improve Function in Seniors with Comorbid Conditions awarded by National Institutes of Health 2008 - 2013
- Mechanisms of RGC Loss in a Murine Model of Glaucoma awarded by National Institutes of Health 2009 - 2012
- Immune Responses in Macular Degeneration awarded by National Institutes of Health 2005 - 2011
- Retinol, Lipofuscin & Autofluorescence in Dry Age-Related Macular Degeneration awarded by National Institutes of Health 2008 - 2010
- Aging and Vasculogenesis in Macular Degeneration awarded by National Institutes of Health 2004 - 2007
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External Relationships
- Arctic Vision
- Clearside Biomedical
- Eclipse Life Sciences
- Eyedea Bio
- Eyedesis Biosciences
- Pulsar Life Sciences
- Stealth Therapeutics
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Gao, Qitong, Joshua Amason, Scott Cousins, Miroslav Pajic, and Majda Hadziahmetovic. “Automated Identification of Referable Retinal Pathology in Teleophthalmology Setting.” Transl Vis Sci Technol 10, no. 6 (May 3, 2021): 30. https://doi.org/10.1167/tvst.10.6.30.Full Text Link to Item
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Mettu, Priyatham S., Michael J. Allingham, and Scott W. Cousins. “Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities.” Prog Retin Eye Res 82 (May 2021): 100906. https://doi.org/10.1016/j.preteyeres.2020.100906.Full Text Link to Item
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Alekseev, Oleg, Effy Ojuok, and Scott Cousins. “Multifocal serous retinopathy with pemigatinib therapy for metastatic colon adenocarcinoma.” Int J Retina Vitreous 7, no. 1 (April 23, 2021): 34. https://doi.org/10.1186/s40942-021-00305-9.Full Text Open Access Copy Link to Item
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Allingham, Michael J., Anna Loksztejn, Scott W. Cousins, and Priyatham S. Mettu. “Immunological Aspects of Age-Related Macular Degeneration.” Adv Exp Med Biol 1256 (2021): 143–89. https://doi.org/10.1007/978-3-030-66014-7_6.Full Text Link to Item
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Zhuang, Jie, David J. Madden, Priscila Cunha, Alexandra Badea, Simon W. Davis, Guy G. Potter, Eleonora M. Lad, et al. “Cerebral white matter connectivity, cognition, and age-related macular degeneration.” Neuroimage Clin 30 (2021): 102594. https://doi.org/10.1016/j.nicl.2021.102594.Full Text Open Access Copy Link to Item
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Zuo, Xintong, Jie Zhuang, Nan-Kuei Chen, Scott Cousins, Priscila Cunha, Eleonora M. Lad, David J. Madden, Guy Potter, and Heather E. Whitson. “Relationship between neural functional connectivity and memory performance in age-related macular degeneration.” Neurobiology of Aging 95 (November 2020): 176–85. https://doi.org/10.1016/j.neurobiolaging.2020.07.020.Full Text Open Access Copy
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Gao, Qitong, Ying Xu, Joshua Amason, Anna Loksztejn, Scott Cousins, Miroslav Pajic, and Majda Hadziahmetovic. “Automated Recognition of Retinal Pigment Epithelium Cells on Limited Training Samples Using Neural Networks.” Transl Vis Sci Technol 9, no. 2 (June 2020): 31. https://doi.org/10.1167/tvst.9.2.31.Full Text Link to Item
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Rasti, Reza, Michael J. Allingham, Priyatham S. Mettu, Sam Kavusi, Kishan Govind, Scott W. Cousins, and Sina Farsiu. “Deep learning-based single-shot prediction of differential effects of anti-VEGF treatment in patients with diabetic macular edema.” Biomed Opt Express 11, no. 2 (February 1, 2020): 1139–52. https://doi.org/10.1364/BOE.379150.Full Text Link to Item
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Allingham, Michael J., Priyatham S. Mettu, and Scott W. Cousins. “Aldosterone as a mediator of severity in retinal vascular disease: Evidence and potential mechanisms.” Exp Eye Res 188 (November 2019): 107788. https://doi.org/10.1016/j.exer.2019.107788.Full Text Link to Item
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Hsu, S Tammy, Atalie C. Thompson, Sandra S. Stinnett, Ulrich F. O. Luhmann, Lejla Vajzovic, Anupama Horne, Stefanie G. Schuman, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months.” Ophthalmol Retina 3, no. 8 (August 2019): 637–48. https://doi.org/10.1016/j.oret.2019.03.010.Full Text Link to Item
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Hadziahmetovic, Majda, Peter Nicholas, Sumeet Jindal, Priyatham S. Mettu, and Scott W. Cousins. “Evaluation of a Remote Diagnosis Imaging Model vs Dilated Eye Examination in Referable Macular Degeneration.” Jama Ophthalmol 137, no. 7 (July 1, 2019): 802–8. https://doi.org/10.1001/jamaophthalmol.2019.1203.Full Text Link to Item
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Cousins, S. W., G. T. Kokame, P. S. Mettu, and N. K. Waheed. “MANAGING ANTI–VEGF-RESISTANT NEOVASCULAR AMD: IS IT POLYPOIDAL CHOROIDAL VASCULOPATHY?” Retina 39 (March 1, 2019): 3–11. https://doi.org/10.1097/01.IAE.0000657452.73085.65.Full Text
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Allingham, Michael J., Nomingerel Tserentsoodol, Peter Saloupis, Priyatham S. Mettu, and Scott W. Cousins. “Aldosterone Exposure Causes Increased Retinal Edema and Severe Retinopathy Following Laser-Induced Retinal Vein Occlusion in Mice.” Invest Ophthalmol Vis Sci 59, no. 8 (July 2, 2018): 3355–65. https://doi.org/10.1167/iovs.17-23073.Full Text Link to Item
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Cocce, Kimberly J., Sandra S. Stinnett, Ulrich F. O. Luhmann, Lejla Vajzovic, Anupama Horne, Stefanie G. Schuman, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Visual Function Metrics in Early and Intermediate Dry Age-related Macular Degeneration for Use as Clinical Trial Endpoints.” Am J Ophthalmol 189 (May 2018): 127–38. https://doi.org/10.1016/j.ajo.2018.02.012.Full Text Link to Item
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Zhuang, Jie, David J. Madden, Xuan Duong-Fernandez, Nan-Kuei Chen, Scott W. Cousins, Guy G. Potter, Michele T. Diaz, and Heather E. Whitson. “Language processing in age-related macular degeneration associated with unique functional connectivity signatures in the right hemisphere.” Neurobiology of Aging 63 (March 2018): 65–74. https://doi.org/10.1016/j.neurobiolaging.2017.11.003.Full Text Open Access Copy
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Horne, Alexandra J., Kimberly S. Chiew, Jie Zhuang, Linda K. George, R Alison Adcock, Guy G. Potter, Eleonora M. Lad, et al. “Relating Sensory, Cognitive, and Neural Factors to Older Persons' Perceptions about Happiness: An Exploratory Study.” J Aging Res 2018 (2018): 4930385. https://doi.org/10.1155/2018/4930385.Full Text Open Access Copy Link to Item
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Lad, Eleonora M., Dibyendu Mukherjee, Sandra S. Stinnett, Scott W. Cousins, Guy G. Potter, James R. Burke, Sina Farsiu, and Heather E. Whitson. “Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer's disease.” Plos One 13, no. 2 (2018): e0192646. https://doi.org/10.1371/journal.pone.0192646.Full Text Link to Item
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Thompson, Atalie C., Ulrich F. O. Luhmann, Sandra S. Stinnett, Lejla Vajzovic, Anupama Horne, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration.” Invest Ophthalmol Vis Sci 59, no. 1 (January 1, 2018): 289–97. https://doi.org/10.1167/iovs.17-22528.Full Text Link to Item
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Allingham, Michael J., Dibyendu Mukherjee, Erin B. Lally, Hossein Rabbani, Priyatham S. Mettu, Scott W. Cousins, and Sina Farsiu. “A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study.” Transl Vis Sci Technol 6, no. 2 (March 2017): 7. https://doi.org/10.1167/tvst.6.2.7.Full Text Open Access Copy Link to Item
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Wen, Joanne C., Ester Reina-Torres, Joseph M. Sherwood, Pratap Challa, Katy C. Liu, Guorong Li, Jason Y. H. Chang, et al. “Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration.” Invest Ophthalmol Vis Sci 58, no. 3 (March 1, 2017): 1893–98. https://doi.org/10.1167/iovs.16-20786.Full Text Link to Item
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Cousins, Scott, and Darius M. Moshfeghi. “8 Questions with Dr. Moshfeghi.” Ophthalmic Surg Lasers Imaging Retina 48, no. 2 (February 1, 2017): 191–92. https://doi.org/10.3928/23258160-20170130-16.Full Text Link to Item
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Polans, James, David Cunefare, Eli Cole, Brenton Keller, Priyatham S. Mettu, Scott W. Cousins, Michael J. Allingham, Joseph A. Izatt, and Sina Farsiu. “Enhanced visualization of peripheral retinal vasculature with wavefront sensorless adaptive optics optical coherence tomography angiography in diabetic patients.” Opt Lett 42, no. 1 (January 1, 2017): 17–20. https://doi.org/10.1364/OL.42.000017.Full Text Link to Item
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Zhang, Wenlan, Peter Nicholas, Stefanie Gail Schuman, Michael John Allingham, Ambar Faridi, Tushar Suthar, Scott William Cousins, and Sasapin Grace Prakalapakorn. “Screening for Diabetic Retinopathy Using a Portable, Noncontact, Nonmydriatic Handheld Retinal Camera.” J Diabetes Sci Technol 11, no. 1 (January 2017): 128–34. https://doi.org/10.1177/1932296816658902.Full Text Link to Item
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Wen, Joanne C., Scott W. Cousins, Stefanie G. Schuman, and R Rand Allingham. “DYNAMIC CHANGES OF THE ANTERIOR CHAMBER ANGLE PRODUCED BY INTRAVITREAL ANTI-VASCULAR GROWTH FACTOR INJECTIONS.” Retina 36, no. 10 (October 2016): 1874–81. https://doi.org/10.1097/IAE.0000000000001018.Full Text Link to Item
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Ahadome, Sarah D., Rose Mathew, Nancy J. Reyes, Priyatham S. Mettu, Scott W. Cousins, Virginia L. Calder, and Daniel R. Saban. “Classical dendritic cells mediate fibrosis directly via the retinoic acid pathway in severe eye allergy.” Jci Insight 1, no. 12 (August 4, 2016). https://doi.org/10.1172/jci.insight.87012.Full Text Link to Item
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Chandramohan, Arthika, Sandra S. Stinnett, John T. Petrowski, Stefanie G. Schuman, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “VISUAL FUNCTION MEASURES IN EARLY AND INTERMEDIATE AGE-RELATED MACULAR DEGENERATION.” Retina 36, no. 5 (May 2016): 1021–31. https://doi.org/10.1097/IAE.0000000000001002.Full Text Link to Item
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Allingham, Michael J., Qing Nie, Eleonora M. Lad, Daniel J. Izatt, Priyatham S. Mettu, Scott W. Cousins, and Sina Farsiu. “Semiautomatic Segmentation of Rim Area Focal Hyperautofluorescence Predicts Progression of Geographic Atrophy Due to Dry Age-Related Macular Degeneration.” Invest Ophthalmol Vis Sci 57, no. 4 (April 1, 2016): 2283–89. https://doi.org/10.1167/iovs.15-19008.Full Text Link to Item
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Estrada, Rolando, Michael J. Allingham, Priyatham S. Mettu, Scott W. Cousins, Carlo Tomasi, and Sina Farsiu. “Retinal Artery-Vein Classification via Topology Estimation.” Ieee Trans Med Imaging 34, no. 12 (December 2015): 2518–34. https://doi.org/10.1109/TMI.2015.2443117.Full Text Link to Item
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Chiu, Stephanie J., Michael J. Allingham, Priyatham S. Mettu, Scott W. Cousins, Joseph A. Izatt, and Sina Farsiu. “Kernel regression based segmentation of optical coherence tomography images with diabetic macular edema.” Biomed Opt Express 6, no. 4 (April 1, 2015): 1172–94. https://doi.org/10.1364/BOE.6.001172.Full Text Link to Item
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Whitson, Heather E., Ying-Hui Chou, Guy G. Potter, Michele T. Diaz, Nan-Kuei Chen, Eleonora M. Lad, Micah A. Johnson, Scott W. Cousins, Jie Zhuang, and David J. Madden. “Phonemic fluency and brain connectivity in age-related macular degeneration: a pilot study.” Brain Connectivity 5, no. 2 (March 2015): 126–35. https://doi.org/10.1089/brain.2014.0277.Full Text
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Rabbani, Hossein, Michael J. Allingham, Priyatham S. Mettu, Scott W. Cousins, and Sina Farsiu. “Fully automatic segmentation of fluorescein leakage in subjects with diabetic macular edema.” Invest Ophthalmol Vis Sci 56, no. 3 (January 29, 2015): 1482–92. https://doi.org/10.1167/iovs.14-15457.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Goldis Malek, Priyatham S. Mettu, Alejandro Caicedo, Peter Saloupis, Sarah Gach, Askia K. Dunnon, Peng Hu, Maria-Grazia Spiga, and Scott W. Cousins. “Bone marrow transplantation transfers age-related susceptibility to neovascular remodeling in murine laser-induced choroidal neovascularization.” Invest Ophthalmol Vis Sci 54, no. 12 (November 13, 2013): 7439–49. https://doi.org/10.1167/iovs.13-12546.Full Text Link to Item
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Whitson, Heather E., Diane Whitaker, Guy Potter, Eleanor McConnell, Fay Tripp, Linda L. Sanders, Kelly W. Muir, Harvey J. Cohen, and Scott W. Cousins. “A low-vision rehabilitation program for patients with mild cognitive deficits.” Jama Ophthalmol 131, no. 7 (July 2013): 912–19. https://doi.org/10.1001/jamaophthalmol.2013.1700.Full Text Link to Item
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Whitson, Heather E., Diane Whitaker, Linda L. Sanders, Guy G. Potter, Scott W. Cousins, Deidra Ansah, Eleanor McConnell, et al. “Memory deficit associated with worse functional trajectories in older adults in low-vision rehabilitation for macular disease.” J Am Geriatr Soc 60, no. 11 (November 2012): 2087–92. https://doi.org/10.1111/j.1532-5415.2012.04194.x.Full Text Link to Item
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Khanifar, Aziz A., David E. Lederer, Jason H. Ghodasra, Sandra S. Stinnett, Jane J. Lee, Scott W. Cousins, and Srilaxmi Bearelly. “Comparison of color fundus photographs and fundus autofluorescence images in measuring geographic atrophy area.” Retina 32, no. 9 (October 2012): 1884–91. https://doi.org/10.1097/IAE.0b013e3182509778.Full Text Link to Item
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Mettu, Priyatham S., Albert R. Wielgus, Sally S. Ong, and Scott W. Cousins. “Retinal pigment epithelium response to oxidant injury in the pathogenesis of early age-related macular degeneration.” Mol Aspects Med 33, no. 4 (August 2012): 376–98. https://doi.org/10.1016/j.mam.2012.04.006.Full Text Link to Item
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Curtis, Lesley H., Bradley G. Hammill, Laura G. Qualls, Lisa D. DiMartino, Fang Wang, Kevin A. Schulman, and Scott W. Cousins. “Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 medicare beneficiaries.” Am J Ophthalmol 153, no. 6 (June 2012): 1116-24.e1. https://doi.org/10.1016/j.ajo.2011.11.032.Full Text Link to Item
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Cousins, Scott W., Diego G. Espinosa-Heidmann, Daniel M. Miller, Simone Pereira-Simon, Eleut P. Hernandez, Hsin Chien, Courtney Meier-Jewett, and Richard D. Dix. “Macrophage activation associated with chronic murine cytomegalovirus infection results in more severe experimental choroidal neovascularization.” Plos Pathog 8, no. 4 (2012): e1002671. https://doi.org/10.1371/journal.ppat.1002671.Full Text Link to Item
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Whitson, Heather E., Karen Steinhauser, Natalie Ammarell, Diane Whitaker, Scott W. Cousins, Deidra Ansah, Linda L. Sanders, and Harvey J. Cohen. “Categorizing the effect of comorbidity: a qualitative study of individuals' experiences in a low-vision rehabilitation program.” J Am Geriatr Soc 59, no. 10 (October 2011): 1802–9. https://doi.org/10.1111/j.1532-5415.2011.03602.x.Full Text Link to Item
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Pons, Marianne, Scott W. Cousins, Oscar Alcazar, Gary E. Striker, and Maria E. Marin-Castaño. “Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration.” Am J Pathol 178, no. 6 (June 2011): 2665–81. https://doi.org/10.1016/j.ajpath.2011.02.006.Full Text Link to Item
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Bearelly, Srilaxmi, Aziz A. Khanifar, David E. Lederer, Jane J. Lee, Jason H. Ghodasra, Sandra S. Stinnett, and Scott W. Cousins. “Use of fundus autofluorescence images to predict geographic atrophy progression.” Retina 31, no. 1 (January 2011): 81–86. https://doi.org/10.1097/IAE.0b013e3181e0958b.Full Text Link to Item
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Whitson, Heather E., Deidra Ansah, Linda L. Sanders, Diane Whitaker, Guy G. Potter, Scott W. Cousins, David C. Steffens, Lawrence R. Landerman, Carl F. Pieper, and Harvey Jay Cohen. “Comorbid cognitive impairment and functional trajectories in low vision rehabilitation for macular disease.” Aging Clin Exp Res 23, no. 5–6 (2011): 343–50. https://doi.org/10.1007/BF03325233.Full Text Link to Item
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Curtis, Lesley H., Bradley G. Hammill, Kevin A. Schulman, and Scott W. Cousins. “Risks of mortality, myocardial infarction, bleeding, and stroke associated with therapies for age-related macular degeneration.” Arch Ophthalmol 128, no. 10 (October 2010): 1273–79. https://doi.org/10.1001/archophthalmol.2010.223.Full Text Link to Item
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Pons, Marianne, Scott W. Cousins, Karl G. Csaky, Gary Striker, and Maria E. Marin-Castaño. “Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: implications for age-related macular degeneration.” Am J Pathol 177, no. 3 (September 2010): 1198–1213. https://doi.org/10.2353/ajpath.2010.091108.Full Text Link to Item
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Elliot, Sharon J., Paola Catanuto, Diego G. Espinosa-Heidmann, Pedro Fernandez, Eleut Hernandez, Peter Saloupis, Kenneth Korach, Michael Karl, and Scott W. Cousins. “Estrogen receptor beta protects against in vivo injury in RPE cells.” Exp Eye Res 90, no. 1 (January 2010): 10–16. https://doi.org/10.1016/j.exer.2009.09.001.Full Text Link to Item
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Bearelly, Srilaxmi, and Scott W. Cousins. “Fundus autofluorescence imaging in age-related macular degeneration and geographic atrophy.” Adv Exp Med Biol 664 (2010): 395–402. https://doi.org/10.1007/978-1-4419-1399-9_45.Full Text Link to Item
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Malek, Goldis, Peng Hu, Albert Wielgus, Mary Dwyer, and Scott Cousins. “PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration.” Adv Exp Med Biol 664 (2010): 429–36. https://doi.org/10.1007/978-1-4419-1399-9_49.Full Text Link to Item
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Whitson, Heather E., Deidra Ansah, Diane Whitaker, Guy Potter, Scott W. Cousins, Heather MacDonald, Carl F. Pieper, Lawrence Landerman, David C. Steffens, and Harvey J. Cohen. “Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease.” Arch Gerontol Geriatr 50, no. 2 (2010): 209–12. https://doi.org/10.1016/j.archger.2009.03.010.Full Text Link to Item
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Alcazar, Oscar, Scott W. Cousins, Gary E. Striker, and Maria E. Marin-Castano. “(Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling.” Exp Eye Res 89, no. 5 (November 2009): 638–47. https://doi.org/10.1016/j.exer.2009.06.014.Full Text Link to Item
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Alcazar, Oscar, Adam M. Hawkridge, Timothy S. Collier, Scott W. Cousins, Sanjoy K. Bhattacharya, David C. Muddiman, and Maria E. Marin-Castano. “Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells.” Mol Cell Proteomics 8, no. 10 (October 2009): 2201–11. https://doi.org/10.1074/mcp.M900203-MCP200.Full Text Link to Item
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Praddaude, Françoise, Scott W. Cousins, Christiane Pêcher, and Maria E. Marin-Castaño. “Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium.” Exp Eye Res 89, no. 1 (June 15, 2009): 109–18. https://doi.org/10.1016/j.exer.2009.02.020.Full Text Link to Item
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Zhou, Q., H. A. Leder, B. P. W. Lo, G. C. Reed, R. W. Knighton, and S. W. Cousins. “Fundus depolarization imaging with GDx™ VCC scanning laser polarimeter and depolarization characteristics of normal eyes.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7163 (May 13, 2009). https://doi.org/10.1117/12.809308.Full Text
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Catanuto, Paola, Diego Espinosa-Heidmann, Simone Pereira-Simon, Patricia Sanchez, Pedro Salas, Eleut Hernandez, Scott W. Cousins, and Sharon J. Elliot. “Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology.” Exp Eye Res 88, no. 1 (January 2009): 99–105. https://doi.org/10.1016/j.exer.2008.10.013.Full Text Link to Item
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Striker, Gary E., Francoiçe Praddaude, Oscar Alcazar, Scott W. Cousins, and Maria E. Marin-Castaño. “Regulation of angiotensin II receptors and extracellular matrix turnover in human retinal pigment epithelium: role of angiotensin II.” Am J Physiol Cell Physiol 295, no. 6 (December 2008): C1633–46. https://doi.org/10.1152/ajpcell.00092.2008.Full Text Link to Item
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Cousins, Scott W., Srilaxmi Bearelly, Maria A. Reinoso, Sulene L. Chi, and Diego G. Espinosa-Heidmann. “Dynamic indocyanine green angiography-guided focal thermal laser treatment of fibrotic choroidal neovascularization.” Graefes Arch Clin Exp Ophthalmol 246, no. 12 (December 2008): 1677–83. https://doi.org/10.1007/s00417-008-0905-5.Full Text Link to Item
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Thill, Michelle, Natalya V. Strunnikova, Marc J. Berna, Nataliya Gordiyenko, Kristin Schmid, Scott W. Cousins, Darby J. S. Thompson, and Karl G. Csaky. “Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.” Invest Ophthalmol Vis Sci 49, no. 6 (June 2008): 2696–2708. https://doi.org/10.1167/iovs.07-0955.Full Text Link to Item
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Elliot, Sharon, Paola Catanuto, Pedro Fernandez, Diego Espinosa-Heidmann, Michael Karl, Kenneth Korach, and Scott W. Cousins. “Subtype specific estrogen receptor action protects against changes in MMP-2 activation in mouse retinal pigmented epithelial cells.” Exp Eye Res 86, no. 4 (April 2008): 653–60. https://doi.org/10.1016/j.exer.2008.01.010.Full Text Link to Item
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Bearelly, S., D. G. Espinosa-Heidmann, and S. W. Cousins. “The role of dynamic indocyanine green angiography in the diagnosis and treatment of retinal angiomatous proliferation.” Br J Ophthalmol 92, no. 2 (February 2008): 191–96. https://doi.org/10.1136/bjo.2007.118760.Full Text Link to Item
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Alcazar, Oscar, Scott W. Cousins, and Maria E. Marin-Castaño. “MMP-14 and TIMP-2 overexpression protects against hydroquinone-induced oxidant injury in RPE: implications for extracellular matrix turnover.” Invest Ophthalmol Vis Sci 48, no. 12 (December 2007): 5662–70. https://doi.org/10.1167/iovs.07-0392.Full Text Link to Item
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Whitson, Heather E., Scott W. Cousins, Bruce M. Burchett, Celia F. Hybels, Carl F. Pieper, and Harvey J. Cohen. “The combined effect of visual impairment and cognitive impairment on disability in older people.” J Am Geriatr Soc 55, no. 6 (June 2007): 885–91. https://doi.org/10.1111/j.1532-5415.2007.01093.x.Full Text Link to Item
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Marin-Castaño, Maria E., Gary E. Striker, Oscar Alcazar, Paola Catanuto, Diego G. Espinosa-Heidmann, and Scott W. Cousins. “Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo.” Invest Ophthalmol Vis Sci 47, no. 9 (September 2006): 4098–4112. https://doi.org/10.1167/iovs.05-1230.Full Text Link to Item
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Elliot, Sharon, Paola Catanuto, William Stetler-Stevenson, and Scott W. Cousins. “Retinal pigment epithelium protection from oxidant-mediated loss of MMP-2 activation requires both MMP-14 and TIMP-2.” Invest Ophthalmol Vis Sci 47, no. 4 (April 2006): 1696–1702. https://doi.org/10.1167/iovs.05-1258.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Ivan J. Suner, Paola Catanuto, Eleut P. Hernandez, Maria E. Marin-Castano, and Scott W. Cousins. “Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD.” Invest Ophthalmol Vis Sci 47, no. 2 (February 2006): 729–37. https://doi.org/10.1167/iovs.05-0719.Full Text Link to Item
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Marin-Castaño, Maria E., Karl G. Csaky, and Scott W. Cousins. “Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.” Invest Ophthalmol Vis Sci 46, no. 9 (September 2005): 3331–40. https://doi.org/10.1167/iovs.04-1224.Full Text Link to Item
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Caicedo, Alejandro, Diego G. Espinosa-Heidmann, Yolanda Piña, Eleut P. Hernandez, and Scott W. Cousins. “Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization.” Exp Eye Res 81, no. 1 (July 2005): 38–47. https://doi.org/10.1016/j.exer.2005.01.013.Full Text Link to Item
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Dix, R. D., and S. W. Cousins. “Cell-mediated cytotoxicity of murine cytomegalovirus-infected target cells allows for release of residual infectious virus.” Arch Virol 150, no. 4 (April 2005): 797–803. https://doi.org/10.1007/s00705-004-0459-8.Full Text Link to Item
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Caicedo, Alejandro, Diego G. Espinosa-Heidmann, Duco Hamasaki, Yolanda Piña, and Scott W. Cousins. “Photoreceptor synapses degenerate early in experimental choroidal neovascularization.” J Comp Neurol 483, no. 3 (March 14, 2005): 263–77. https://doi.org/10.1002/cne.20413.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Maria A. Reinoso, Yolanda Pina, Karl G. Csaky, Alejandro Caicedo, and Scott W. Cousins. “Quantitative enumeration of vascular smooth muscle cells and endothelial cells derived from bone marrow precursors in experimental choroidal neovascularization.” Exp Eye Res 80, no. 3 (March 2005): 369–78. https://doi.org/10.1016/j.exer.2004.10.005.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Maria E. Marin-Castano, Simone Pereira-Simon, Eleut P. Hernandez, Sharon Elliot, and Scott W. Cousins. “Gender and estrogen supplementation increases severity of experimental choroidal neovascularization.” Exp Eye Res 80, no. 3 (March 2005): 413–23. https://doi.org/10.1016/j.exer.2004.10.008.Full Text Link to Item
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Dix, R. D., C. O. Ekworomadu, E. Hernandez, and S. W. Cousins. “Perforin knockout mice, but not mice with MAIDS, show protection against experimental cytomegalovirus retinitis after adoptive transfer of immune cells with a functional perforin cytotoxic pathway.” Arch Virol 149, no. 11 (November 2004): 2235–44. https://doi.org/10.1007/s00705-004-0370-3.Full Text Link to Item
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Dix, Richard D., and Scott W. Cousins. “Interleukin-2 immunotherapy and AIDS-related cytomegalovirus retinitis.” Curr Hiv Res 2, no. 4 (October 2004): 333–42. https://doi.org/10.2174/1570162043351066.Full Text Link to Item
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Strunnikova, Nataly, Connie Zhang, Diane Teichberg, Scott W. Cousins, Judit Baffi, Kevin G. Becker, and Karl G. Csaky. “Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis.” Invest Ophthalmol Vis Sci 45, no. 10 (October 2004): 3767–77. https://doi.org/10.1167/iovs.04-0311.Full Text Link to Item
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Miller, Daniel M., Diego G. Espinosa-Heidmann, Jessica Legra, Sander R. Dubovy, Ivan J. SĹ©ner, Daniel D. Sedmak, Richard D. Dix, and Scott W. Cousins. “The association of prior cytomegalovirus infection with neovascular age-related macular degeneration.” Am J Ophthalmol 138, no. 3 (September 2004): 323–28. https://doi.org/10.1016/j.ajo.2004.03.018.Full Text Link to Item
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Cousins, Scott W., Diego G. Espinosa-Heidmann, and Karl G. Csaky. “Monocyte activation in patients with age-related macular degeneration: a biomarker of risk for choroidal neovascularization?” Arch Ophthalmol 122, no. 7 (July 2004): 1013–18. https://doi.org/10.1001/archopht.122.7.1013.Full Text Link to Item
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Csaky, Karl G., Judit Z. Baffi, Gordon A. Byrnes, Jeremy D. Wolfe, Sara C. Hilmer, Jessica Flippin, and Scott W. Cousins. “Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor.” Exp Eye Res 78, no. 6 (June 2004): 1107–16. https://doi.org/10.1016/j.exer.2004.01.010.Full Text Link to Item
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Espinosa-Heidmann, Diego G., John Sall, Eleut P. Hernandez, and Scott W. Cousins. “Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E.” Invest Ophthalmol Vis Sci 45, no. 1 (January 2004): 260–66. https://doi.org/10.1167/iovs.03-0910.Full Text Link to Item
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Suñer, Ivan J., Diego G. Espinosa-Heidmann, Maria E. Marin-Castano, Eleut P. Hernandez, Simone Pereira-Simon, and Scott W. Cousins. “Nicotine increases size and severity of experimental choroidal neovascularization.” Invest Ophthalmol Vis Sci 45, no. 1 (January 2004): 311–17. https://doi.org/10.1167/iovs.03-0733.Full Text Link to Item
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Dix, Richard D., and Scott W. Cousins. “Susceptibility to murine cytomegalovirus retinitis during progression of MAIDS: correlation with intraocular levels of tumor necrosis factor-alpha and interferon-gamma.” Curr Eye Res 29, no. 2–3 (2004): 173–80. https://doi.org/10.1080/02713680490504876.Full Text Link to Item
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Dix, Richard D., and Scott W. Cousins. “AIDS-related cytomegalovirus retinitis: lessons from the laboratory.” Curr Eye Res 29, no. 2–3 (2004): 91–101. https://doi.org/10.1080/02713680490504641.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Alejandro Caicedo, Eleut P. Hernandez, Karl G. Csaky, and Scott W. Cousins. “Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization.” Invest Ophthalmol Vis Sci 44, no. 11 (November 2003): 4914–19. https://doi.org/10.1167/iovs.03-0371.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Ivan J. Suner, Eleut P. Hernandez, Dagoberto Monroy, Karl G. Csaky, and Scott W. Cousins. “Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization.” Invest Ophthalmol Vis Sci 44, no. 8 (August 2003): 3586–92. https://doi.org/10.1167/iovs.03-0038.Full Text Link to Item
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Dix, Richard D., Eckhard R. Podack, and Scott W. Cousins. “Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA.” Antiviral Res 59, no. 2 (July 2003): 111–19. https://doi.org/10.1016/s0166-3542(03)00066-4.Full Text Link to Item
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Zhang, Congxiao, Judit Baffi, Scott W. Cousins, and Karl G. Csaky. “Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor.” J Cell Sci 116, no. Pt 10 (May 15, 2003): 1915–23. https://doi.org/10.1242/jcs.00390.Full Text Link to Item
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Cousins, Scott W., Maria E. Marin-Castaño, Diego G. Espinosa-Heidmann, Anastassia Alexandridou, Liliane Striker, and Sharon Elliot. “Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice.” Invest Ophthalmol Vis Sci 44, no. 3 (March 2003): 1221–29. https://doi.org/10.1167/iovs.02-0285.Full Text Link to Item
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Dix, Richard D., Eckhard R. Podack, and Scott W. Cousins. “Loss of the perforin cytotoxic pathway predisposes mice to experimental cytomegalovirus retinitis.” J Virol 77, no. 6 (March 2003): 3402–8. https://doi.org/10.1128/jvi.77.6.3402-3408.2003.Full Text Link to Item
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Marin-Castaño, Maria E., Sharon J. Elliot, Mylen Potier, Michael Karl, Liliane J. Striker, Gary E. Striker, Karl G. Csaky, and Scott W. Cousins. “Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium.” Invest Ophthalmol Vis Sci 44, no. 1 (January 2003): 50–59. https://doi.org/10.1167/iovs.01-1276.Full Text Link to Item
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Dix, Richard D., and Scott W. Cousins. “Interleukin-2 immunotherapy of murine cytomegalovirus retinitis during MAIDS correlates with increased intraocular CD8+ T-cell infiltration.” Ophthalmic Res 35, no. 3 (2003): 154–59. https://doi.org/10.1159/000070051.Full Text Link to Item
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Dix, Richard, and Scott Cousins. “Murine cytomegalovirus retinitis during MAIDS: Susceptibility correlates with elevated intraocular levels of interleukin-4 mRNA.” Curr Eye Res 26, no. 3–4 (2003): 211–17. https://doi.org/10.1076/ceyr.26.3.211.14902.Full Text Link to Item
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Cousins, Scott W., Diego G. Espinosa-Heidmann, Anastasia Alexandridou, John Sall, Sander Dubovy, and Karl Csaky. “The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation.” Exp Eye Res 75, no. 5 (November 2002): 543–53. https://doi.org/10.1006/exer.2002.2047.Full Text Link to Item
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Espinosa-Heidmann, Diego G., Ivan Suner, Eleut P. Hernandez, William D. Frazier, Karl G. Csaky, and Scott W. Cousins. “Age as an independent risk factor for severity of experimental choroidal neovascularization.” Invest Ophthalmol Vis Sci 43, no. 5 (May 2002): 1567–73.Link to Item
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Budenz, D. L., K. E. Taba, W. J. Feuer, R. Eliezer, S. Cousins, J. Henderer, and H. W. Flynn. “Surgical management of secondary glaucoma after pars plana vitrectomy and silicone oil injection for complex retinal detachment.” Ophthalmology 108, no. 9 (September 2001): 1628–32. https://doi.org/10.1016/s0161-6420(01)00658-3.Full Text Link to Item
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Strunnikova, N., J. Baffi, A. Gonzalez, W. Silk, S. W. Cousins, and K. G. Csaky. “Regulated heat shock protein 27 expression in human retinal pigment epithelium.” Invest Ophthalmol Vis Sci 42, no. 9 (August 2001): 2130–38.Link to Item
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Jaffe, G. J., C. S. Yang, X. C. Wang, S. W. Cousins, R. P. Gallemore, and P. Ashton. “Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis.” Ophthalmology 105, no. 1 (January 1998): 46–56. https://doi.org/10.1016/s0161-6420(98)91176-9.Full Text Link to Item
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Dix, R. D., M. Giedlin, and S. W. Cousins. “Systemic cytokine immunotherapy for experimental cytomegalovirus retinitis in mice with retrovirus-induced immunodeficiency.” Invest Ophthalmol Vis Sci 38, no. 7 (June 1997): 1411–17.Link to Item
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Dix, R. D., C. Cray, and S. W. Cousins. “Antibody alone does not prevent experimental cytomegalovirus retinitis in mice with retrovirus-induced immunodeficiency (MAIDS).” Ophthalmic Res 29, no. 6 (1997): 381–92. https://doi.org/10.1159/000268039.Full Text Link to Item
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Rubsamen, P. E., S. W. Cousins, and J. A. Martinez. “Impact of cultures on management decisions following surgical repair of penetrating ocular trauma.” Ophthalmic Surg Lasers 28, no. 1 (January 1997): 43–49.Link to Item
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Rubsamen, P. E., and S. W. Cousins. “Therapeutic effect of periocular corticosteroids in experimental proliferative vitreoretinopathy.” Retina 17, no. 1 (1997): 44–50. https://doi.org/10.1097/00006982-199701000-00009.Full Text Link to Item
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Flynn, J. T., and S. Cousins. “Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization.” Surv Ophthalmol 41, no. 3 (1996): 271–72. https://doi.org/10.1016/s0039-6257(96)80032-4.Full Text Link to Item
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Thompson, W. S., P. E. Rubsamen, H. W. Flynn, J. Schiffman, and S. W. Cousins. “Endophthalmitis after penetrating trauma. Risk factors and visual acuity outcomes.” Ophthalmology 102, no. 11 (November 1995): 1696–1701. https://doi.org/10.1016/s0161-6420(95)30807-x.Full Text Link to Item
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Cousins, S. W. “Intraocular immunosuppression as treatment for uveitis: Rationale, preliminary results, and future prospects.” Regional Immunology 6, no. 1–2 (December 1, 1994): 191–201.
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Dix, R. D., C. Cray, and S. Cousins. “Cytomegalovirus retinitis during AIDS: Current issues and future directions.” Regional Immunology 6, no. 1–2 (December 1, 1994): 112–18.
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Cousins, S. W., and P. E. Rubsamen. “Comparison of flow cytometry with the surgeon regarding ability to predict the ultimate success of surgery for proliferative vitreoretinopathy.” Arch Ophthalmol 112, no. 12 (December 1994): 1554–60. https://doi.org/10.1001/archopht.1994.01090240060026.Full Text Link to Item
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Taylor, A. W., J. W. Streilein, and S. W. Cousins. “Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor.” J Immunol 153, no. 3 (August 1, 1994): 1080–86.Link to Item
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Dix, R. D., C. Cray, and S. W. Cousins. “Mice immunosuppressed by murine retrovirus infection (MAIDS) are susceptible to cytomegalovirus retinitis.” Curr Eye Res 13, no. 8 (August 1994): 587–95. https://doi.org/10.3109/02713689408999892.Full Text Link to Item
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Rubsamen, P. E., S. W. Cousins, K. E. Winward, and S. F. Byrne. “Diagnostic ultrasound and pars plana vitrectomy in penetrating ocular trauma.” Ophthalmology 101, no. 5 (May 1994): 809–14. https://doi.org/10.1016/s0161-6420(94)31254-1.Full Text Link to Item
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Rubsamen, P. E., P. A. Davis, E. Hernandez, G. E. O’Grady, and S. W. Cousins. “Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal implant for the sustained release of fluorouracil.” Arch Ophthalmol 112, no. 3 (March 1994): 407–13. https://doi.org/10.1001/archopht.1994.01090150137036.Full Text Link to Item
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Azumi, A., S. W. Cousins, M. Y. Kanter, and S. S. Atherton. “Modulation of murine herpes simplex virus type 1 retinitis in the uninoculated eye by CD4+ T lymphocytes.” Invest Ophthalmol Vis Sci 35, no. 1 (January 1994): 54–63.Link to Item
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Taylor, A. W., J. W. Streilein, and S. W. Cousins. “Alpha-melanocyte-stimulating hormone suppresses antigen-stimulated T cell production of gamma-interferon.” Neuroimmunomodulation 1, no. 3 (1994): 188–94. https://doi.org/10.1159/000097167.Full Text Link to Item
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Taylor, A. W., J. W. Streilein, and S. W. Cousins. “Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor.” Curr Eye Res 11, no. 12 (December 1992): 1199–1206. https://doi.org/10.3109/02713689208999545.Full Text Link to Item
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Atherton, S. S., C. K. Newell, M. Y. Kanter, and S. W. Cousins. “T cell depletion increases susceptibility to murine cytomegalovirus retinitis.” Invest Ophthalmol Vis Sci 33, no. 12 (November 1992): 3353–60.Link to Item
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Streilein, J. W., G. A. Wilbanks, and S. W. Cousins. “Immunoregulatory mechanisms of the eye.” J Neuroimmunol 39, no. 3 (August 1992): 185–200. https://doi.org/10.1016/0165-5728(92)90253-h.Full Text Link to Item
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Yang, C. M., and S. W. Cousins. “Quantitative assessment of growth stimulating activity of the vitreous during PVR.” Invest Ophthalmol Vis Sci 33, no. 8 (July 1992): 2436–42.Link to Item
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Streilein, J. W., S. Cousins, and D. Bradley. “Effect of intraocular gamma-interferon on immunoregulatory properties of iris and ciliary body cells.” Invest Ophthalmol Vis Sci 33, no. 7 (June 1992): 2304–15.Link to Item
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Cousins, S. W. “T cell activation within different intraocular compartments during experimental uveitis.” Dev Ophthalmol 23 (1992): 150–55. https://doi.org/10.1159/000429644.Full Text Link to Item
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Streilein, J. W., G. A. Wilbanks, A. Taylor, and S. Cousins. “Eye-derived cytokines and the immunosuppressive intraocular microenvironment: A review.” Current Eye Research 11, no. SUPPL. (1992): 41–47.
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Streilein, J. W., G. A. Wilbanks, A. Taylor, and S. Cousins. “Eye-derived cytokines and the immunosuppressive intraocular microenvironment: a review.” Curr Eye Res 11 Suppl (1992): 41–47. https://doi.org/10.3109/02713689208999510.Full Text Link to Item
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Yang, C. M., K. R. Olsen, E. Hernandez, and S. W. Cousins. “Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy.” Graefes Arch Clin Exp Ophthalmol 230, no. 1 (1992): 66–71. https://doi.org/10.1007/BF00166765.Full Text Link to Item
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Ksander, B. R., P. E. Rubsamen, K. R. Olsen, S. W. Cousins, and J. W. Streilein. “Studies of tumor-infiltrating lymphocytes from a human choroidal melanoma.” Invest Ophthalmol Vis Sci 32, no. 13 (December 1991): 3198–3208.Link to Item
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Atherton, S. S., C. K. Newell, M. Y. Kanter, and S. W. Cousins. “Retinitis in euthymic mice following inoculation of murine cytomegalovirus (MCMV) via the supraciliary route.” Curr Eye Res 10, no. 7 (July 1991): 667–77. https://doi.org/10.3109/02713689109013858.Full Text Link to Item
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Cousins, S. W., M. M. McCabe, D. Danielpour, and J. W. Streilein. “Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.” Invest Ophthalmol Vis Sci 32, no. 8 (July 1991): 2201–11.Link to Item
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Cousins, S. W., W. B. Trattler, and J. W. Streilein. “Immune privilege and suppression of immunogenic inflammation in the anterior chamber of the eye.” Curr Eye Res 10, no. 4 (April 1991): 287–97. https://doi.org/10.3109/02713689108996334.Full Text Link to Item
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Cousins, S. W., and J. W. Streilein. “Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation.” Invest Ophthalmol Vis Sci 31, no. 10 (October 1990): 2111–22.Link to Item
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Streilein, J. W., S. Cousins, and J. S. Williamson. “Ocular molecules and cells that regulate immune responses in situ.” Int Ophthalmol 14, no. 5–6 (October 1990): 317–25. https://doi.org/10.1007/BF00163551.Full Text Link to Item
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Cousins, S. W., H. W. Flynn, and J. G. Clarkson. “Macroaneurysms associated with retinal branch vein occlusion.” Am J Ophthalmol 109, no. 5 (May 15, 1990): 567–70. https://doi.org/10.1016/s0002-9394(14)70687-7.Full Text Link to Item
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Streilein, J. W., and S. W. Cousins. “Aqueous humor factors and their effect on the immune response in the anterior chamber.” Curr Eye Res 9 Suppl (1990): 175–82. https://doi.org/10.3109/02713689008999439.Full Text Link to Item
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Cousins, S. W., A. Gonzalez, and S. S. Atherton. “Herpes simplex retinitis in the mouse. Clinicopathologic correlations.” Invest Ophthalmol Vis Sci 30, no. 7 (July 1989): 1485–94.Link to Item
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Cousins, S. W., N. H. Altman, and S. S. Atherton. “Schisis contributes to necrosis in experimental HSV-1 retinitis.” Exp Eye Res 48, no. 6 (June 1989): 745–60. https://doi.org/10.1016/0014-4835(89)90061-4.Full Text Link to Item
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Kielty, D., S. W. Cousins, and S. S. Atherton. “HSV-1 retinitis and delayed hypersensitivity in DBA/2 and C57BL/6 mice.” Invest Ophthalmol Vis Sci 28, no. 12 (December 1987): 1994–99.Link to Item
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Dix, R. D., J. W. Streilein, S. Cousins, and S. S. Atherton. “Histopathologic characteristics of two forms of experimental herpes simplex virus retinitis.” Curr Eye Res 6, no. 1 (January 1987): 47–52. https://doi.org/10.3109/02713688709020067.Full Text Link to Item
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Cousins, S., I. Boniuk, E. Okun, G. P. Johnston, N. P. Arribas, R. F. Escoffery, D. B. Burgess, M. G. Grand, R. J. Olk, and L. H. Schoch. “Pseudophakic retinal detachments in the presence of various IOL types.” Ophthalmology 93, no. 9 (September 1986): 1198–1208. https://doi.org/10.1016/s0161-6420(86)33596-6.Full Text Link to Item
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Cousins, S. W., R. B. Guss, E. L. Howes, and J. T. Rosenbaum. “Endotoxin-induced uveitis in the rat: observations on altered vascular permeability, clinical findings, and histology.” Exp Eye Res 39, no. 5 (November 1984): 665–76. https://doi.org/10.1016/0014-4835(84)90065-4.Full Text Link to Item
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Cousins, S. W., J. T. Rosenbaum, R. B. Guss, and P. R. Egbert. “Ocular albumin fluorophotometric quantitation of endotoxin-induced vascular permeability.” Infect Immun 36, no. 2 (May 1982): 730–36. https://doi.org/10.1128/iai.36.2.730-736.1982.Full Text Link to Item
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Rosenbaum, J. T., and S. W. Cousins. “Uveitis and arthritis: experimental models and clinical correlates.” Semin Arthritis Rheum 11, no. 4 (May 1982): 383–89. https://doi.org/10.1016/0049-0172(82)90025-7.Full Text Link to Item
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Book Sections
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Csaky, K. G., P. S. Mettu, and S. W. Cousins. “Immunology of age-related macular degeneration.” In Age-Related Macular Degeneration, 10–32, 2012.
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Lederer, D. E., S. W. Cousins, and K. G. Csaky. “Neovascular age-related macular degeneration.” In Ocular Disease: Mechanisms and Management, 536–43, 2010. https://doi.org/10.1016/B978-0-7020-2983-7.00069-3.Full Text
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Kesen, M. R., and S. W. Cousins. “Choroidal neovascularization.” In Encyclopedia of the Eye, 257–65, 2010. https://doi.org/10.1016/B978-0-12-374203-2.00143-3.Full Text
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Kesen, M. R., and S. W. Cousins. “Choroidal neovascularization.” In Encyclopedia of the Eye, Four-Volume Set, 257–65, 2010. https://doi.org/10.1016/B978-0-12-374203-2.00143-3.Full Text
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Csaky, K. G., and S. W. Cousins. “Immunology of age-related macular degeneration.” In Age-Related Macular Degeneration, Second Edition, 11–34, 2007.
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Cousins, S. W., K. G. Csaky, and D. G. Espinosa-Heidmann. “Clinical strategies for diagnosis and treatment of AMD: Implications from research.” In Macular Degeneration, 167–200, 2005. https://doi.org/10.1007/3-540-26977-0_10.Full Text
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Cousins, S. W., and K. G. Csaky. “Immunology of age-related macular degeneration.” In Age-Related Macular Degeneration, 27–65, 2002.
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Cousins, S. W., and J. W. Streilein. “Immune privilege and its regulation by immunosuppressive growth factors in aqueous humor,” 81–84, 1990.
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Other Articles
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Lad, Eleonora M., Scott W. Cousins, and Alan D. Proia. “Identity of pigmented subretinal cells in age-related macular degeneration.” Graefes Arch Clin Exp Ophthalmol, June 2016. https://doi.org/10.1007/s00417-015-3249-y.Full Text Link to Item
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Cousins, S. W. “Treatment of DME with the 0.19-mg fluocinolone acetonide implant.” Retina Today, September 1, 2015.
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Cousins, S. W. “Role of mitochondrial dysfunction in dry age-related macular degeneration: The site of intracellular metabolism may be a relevant drug target in dry AMD.” Retina Today, January 1, 2015.
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Puliafito, Carmen A., Pravin U. Dugel, Scott W. Cousins, Kirk H. Packo, Alexander M. Eaton, Richard K. Parrish, Szilárd Kiss, and Elias Reichel. “Improving Outcomes for Patients With Diabetic Macular Edema.” Ophthalmic Surg Lasers Imaging Retina, 2015. https://doi.org/10.3928/23258160-20151124-01.Full Text Link to Item
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Curtis, L. H., B. G. Hammill, K. A. Schulman, and S. W. Cousins. “In reply.” Archives of Ophthalmology, June 1, 2012. https://doi.org/10.1001/archophthalmol.2012.100.Full Text
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Curtis, L. H., B. G. Hammill, K. A. Schulman, and S. W. Cousins. “In reply.” Archives of Ophthalmology, January 1, 2012. https://doi.org/10.1001/archopht.130.1.125.Full Text
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Curtis, Lesley H., Bradley G. Hammill, Kevin A. Schulman, and Scott W. Cousins. “Systemic and Ocular Risks Associated With Therapies for Macular Degeneration: Clarification vs Confusion reply.” Archives of Ophthalmology, 2012.Link to Item
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Curtis, Lesley H., Bradley G. Hammill, Kevin A. Schulman, and Scott W. Cousins. “Risks of Adverse Events With Therapies for Age-Related Macular Degeneration: A Response.” Archives of Ophthalmology. AMER MEDICAL ASSOC, January 1, 2012.Link to Item
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Boyer, D. S., M. A. Busquets, S. W. Cousins, P. U. Dugel, J. S. Heier, and M. A. Singer. “New and emerging treatment paradigms for macular Edema in retinal vein occlusion and diabetic retinopathy.” Retina Today, October 1, 2009.
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Cousins, S. W. “Intravitreal anti-VEGF and anti-PDGF combination therapy.” Retina Today, October 1, 2009.
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Malek, G., and S. W. Cousins. “Is our current clinical classification of AMD up to the job?” Br J Ophthalmol, September 2006. https://doi.org/10.1136/bjo.2006.098715.Full Text Link to Item
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Cousins, S. W., D. G. Espinosa-Heidmann, A. Alexandridou, J. Sall, S. Dubovy, and K. Csaky. “Erratum: The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation (Experimental Eye Research (2002) 75 (543-553)).” Experimental Eye Research, April 1, 2003. https://doi.org/10.1016/S0014-4835(03)00025-3.Full Text
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Yang, C. M., and S. W. Cousins. “Fate of the fellow eye after Propionibacterium acnes endophthalmitis.” Am J Ophthalmol, July 15, 1991. https://doi.org/10.1016/s0002-9394(14)76227-0.Full Text Link to Item
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Conference Papers
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Labowsky, Mary, Sandra Stinnett, Ulrich F. O. Luhmann, Lejla Vajzovic, Anupama Horne, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Use of mobile MyVisionTrack (mVT) technology as a remote visual function metric in Early and Intermediate Age-Related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Thompson, Atalie C., Sandra Stinnett, Ulrich F. O. Luhmann, Vaishali Oza, Lejla Vajzovic, Anupama Horne, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Longitudinal progression of visual function metrics in early and intermediate age-related macular degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Cunha, P. P., J. Zhuang, J. P. Wright, D. J. Madden, G. G. Potter, K. Allen, E. Lad, S. W. Cousins, and H. Whitson. “Discrepancy between self-reported vision and visual acuity in patients with age-related macular degeneration.” In Journal of the American Geriatrics Society, 66:S315–S315. WILEY, 2018.Link to Item
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Allingham, Michael J., Nomingerel Tserentsoodol, Peter Saloupis, and Scott W. Cousins. “Low dose aldosterone exposure causes increased retinal edema following laser-induced retinal vein occlusion in mice.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Cocce, Kimberly, Sandra Stinnett, Lejla Vajzovic, Anupama Horne, Cynthia A. Toth, Scott W. Cousins, and Eleonora M. Lad. “Visual function endpoints in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Foster, Melanie Louise, Regan L. Lane, Annie Oh, Steven Nagar, Mary Christine McGahan, Priyatham S. Mettu, Scott W. Cousins, and Freya M. Mowat. “The retinal pigment epithelium of the canine area centralis is uniquely susceptible to mitochondrial toxicant damage.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Jindal, Sumeet, Scott W. Cousins, and Priyatham S. Mettu. “Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for Treatment of Serous Pigment Epithelium Detachments in Neovascular Age-Related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Mettu, Priyatham S., Michael J. Allingham, Peter Nicholas, and Scott W. Cousins. “Adjunctive Indocyanine Green Angiography-Directed Verteporfin Photodynamic Therapy for the Treatment of Persistent Disease Activity in Neovascular AMD.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Mowat, Freya M., Annie Oh, Melanie Louise Foster, Priyatham S. Mettu, and Scott W. Cousins. “Repetitive periocular delivery of hydroquinone in canines results in dysfunction of central retinal cone photoreceptors.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Thompson, Atalie C., Sandra Stinnett, Lejla Vajzovic, Anupama Horne, Cynthia A. Toth, Scott W. Cousins, and Eleanora M. Lad. “Association of Low Luminance Questionnaire with Objective Functional Measures in Age-related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Allingham, Michael J., Dibyendu Mukherjee, Erin Lally, Hossein Rabbani, Priyatham S. Mettu, Scott W. Cousins, and Sina Farsiu. “A quantitative approach to predict differential effects of anti-VEGF treatment on diffuse and focal leakage in patients with diabetic macular edema.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Cousins, Scott W., Peter Saloupis, Mulugu V. Brahmajoti, and Priyatham S. Mettu. “Mitochondrial Dysfunction in Experimental Mouse Models of SubRPE Deposit Formation and Reversal by the Mito-Reparative Drug MTP-131.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Mettu, Priyatham S., Michael J. Allingham, Peter C. Nicholas, and Scott W. Cousins. “Neovascular Morphology by ICG Angiography and Response to Loading-Dose Anti-VEGF Therapy in Patients with Neovascular AMD.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Nicholas, Peter C., Priyatham S. Mettu, and Scott W. Cousins. “Feasibility and acceptance of retinal imaging in a medical clinic by non-expert imagers.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Whitson, Heather, Sina Farsiu, Sandra S. Stinnett, Leon Kwark, Guy Potter, James Burke, Scott W. Cousins, and Eleonora M. Lad. “Retinal Biomarkers of Alzheimer's Disease.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Puliafito, Carmen A., Scott W. Cousins, Jason Bacharach, Victor H. Gonzalez, Nancy M. Holekamp, Pauline T. Merrill, Matthew P. Ohr, Richard K. Parrish, and Christopher D. Riemann. “Forming a Consensus: Data and Guidance for Physicians Treating Diabetic Macular Edema.” In Ophthalmic Surg Lasers Imaging Retina, 47:S4–15, 2016. https://doi.org/10.3928/23258160-20160224-01.Full Text Link to Item
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Allingham, Michael J., Daniel Izatt, Qing Nie, Eleonora M. Lad, Priyatham S. Mettu, Scott W. Cousins, and Sina Farsiu. “Robust, easy-to-use, semiautomated software quantifies lesion rim area hyperautofluorescence and predicts progression of geographic atrophy.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Chandramohan, Arthika, Jonathan P. Wright, Xuan Duong Fernandez, Jie Zhuang, Leon Kwark, Sina Farsiu, Scott W. Cousins, David Madden, Eleonora M. Lad, and Heather E. Whitson. “Relationships between Retinal Nerve Fiber Layer and Brain Changes in Age-Related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Cousins, Scott W., Priyatham S. Mettu, and Mulugu V. Brahmajothi. “The mitochondria-targeted peptide MTP-131 prevents hydroquinone-mediated persistent injury phenotype in cultured retinal pigment epithelium cells.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Dale, Sarah B., Tomas Blanco, Rose Mathew, Priyatham S. Mettu, Scott W. Cousins, Virginia L. Calder, and Daniel Saban. “CD11b(+) Classical Dendritic Cells (cDC) Directly Effect Fibrosis in Ocular Surface Inflammation.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Hess, Riikka, Mulugu V. Brahmajothi, Peter Saloupis, Priyatham S. Mettu, and Scott W. Cousins. “Repetitive periocular injection of hydroquinone promotes mitochondrial dysfunction in retinal pigment epithelium of mouse eyes.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Lad, Eleonora M., Scott W. Cousins, Sina Farsiu, and Alan D. Proia. “Retinal Macrophages in Stages of Age-related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Mettu, Priyatham S., Peter Saloupis, Daniel Saban, and Scott W. Cousins. “Increased Frequency of Nonclassical Monocytes in the Blood is Correlated with Development of Neovascular Remodeling in Experimental Choroidal Neovascularization.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Wen, Joanne C., Scott W. Cousins, Stefanie Schuman, and R Rand Allingham Allingham. “Intravitreal injections cause anterior chamber angle narrowing in patients receiving anti-VEGF treatment.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Wright, Jonathan P., Arthika Chandramohan, Xuan Duong Fernandez, Eleonora Lad, Jie Zhuang, Scott W. Cousins, and Heather E. Whitson. “Is discrepancy in self-reported vision and visual acuity related to neurocognitive status of AMD patients?” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Zhang, Wenlan, Peter Nicholas, Stefanie Schuman, Michael Allingham, Ambar Faridi, Suthar Tushar, Scott W. Cousins, and Sasapin Grace Prakalapakorn. “Screening for Diabetic Retinopathy Using the Hand-Held PICTOR Camera.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Whitson, Heather E., Sina Farsiu, Sandra Stinnett, Sung Lee, Leon Kwark, Guy Potter, James Burke, Scott W. Cousins, and Eleonora Lad. “Retinal imaging biomarkers for early diagnosis of Alzheimer's disease.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Suñer, I. J., M. C. Peden, M. E. Hammer, W. S. Grizzard, J. Traynom, and S. W. Cousins. “RaScaL: A pilot study to assess the efficacy, durability, and safety of a single intervention with ranibizumab plus peripheral laser for diabetic macular edema associated with peripheral nonperfusion on ultrawide-field fluorescein angiography.” In Ophthalmologica, 233:89–95, 2015. https://doi.org/10.1159/000367902.Full Text
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Lad, Eleonora M., Arthika Chandramohan, Alice Ventura, and Scott W. Cousins. “Evaluation of visual function impairments in patients with dry age-related macular degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Mettu, Priyatham S., Peter Saloupis, and Scott W. Cousins. “PAMP Stimulation of Macrophages Promotes Neovascular Remodeling in Experimental Choroidal Neovascularization.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Wen, Joanne C., Darryl R. Overby, Michael Madekurozwa, Brian Chu, Priyatham S. Mettu, Stefanie G. Schuman, Pratap Challa, Scott W. Cousins, and R Rand Allingham. “The effect of anti-VEGF injections on tonographic aqueous outflow facility and a novel method to calculate facility using the post-injection IOP decay curve.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Bearelly, S., S. Raghunath, A. A. Khanifar, S. W. Cousins, and S. Farsiu. “Quantitative Evaluation of Fundus Autofluorescence Images to Predict Geographic Atrophy Progression.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Cousins, S. W. “Targeting Complement Factor 5 in Combination with Vascular Endothelial Growth Factor (VEGF) Inhibition for Neovascular Age Related Macular Degeneration (AMD): Results of a Phase 1 Study.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Dunnon, A. K., P. Saloupis, T. Pridgen, K. Wu, G. Malek, and S. W. Cousins. “Different Patterns of Neovascularization Are Determined by Different Pro-Angiogenic Stimuli.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Espinosa-Heidmann, D. G., G. Malek, K. Wu, P. Saloupis, and S. W. Cousins. “Osteopontin Regulation of Choroidal Neovascular Fibrosis Through Macrophages.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Jewett, CL Meier, H. Chien, S. W. Cousins, and R. D. Dix. “Ganciclovir Treatment of Mice Chronically Infected With Murine Cytomegalovirus Decreases Vegf Production by Splenic Macrophages.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Malek, G., P. Hu, M. Dwyer, S. W. Cousins, and D. P. McDonnell. “Expression Profiling of Nuclear Receptors in Human Retinal Pigment Epithelial Cells: Relevance to Age-Related Macular Degeneration.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Pons, M., O. Alcazar, S. W. Cousins, K. G. Csaky, and M. E. Marin-Castano. “Cigarette Smoke-Related Hydroquinone Induces F-Actin Reorganization and Hsp27 Phosphorylation Through p38 and ERK1/2 in Retinal Pigment Epithelium.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Whitson, H., D. Ansah, L. L. Sanders, D. Whitaker, G. Potter, S. W. Cousins, D. C. Steffens, L. R. Landerman, C. F. Pieper, and H. J. Cohen. “Comorbid Cognitive Impairment and Functional Trajectories in Low Vision Rehabilitation.” In Journal of the American Geriatrics Society, 58:128–29. WILEY-BLACKWELL PUBLISHING, INC, 2010.Link to Item
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Wielgus, A. R., S. W. Cousins, and G. Malek. “Effects of Sub-Lethal Levels of Omega-3 and-6 Polyunsaturated Fatty Acid Oxidation End Products in RPE Cell Culture.” In Investigative Ophthalmology & Visual Science, Vol. 51. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2010.Link to Item
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Whitson, H. E., S. W. Cousins, B. M. Burchett, C. F. Hybels, C. F. Pieper, and H. J. Cohen. “The combined impact of cognitive and visual impairment on disability.” In Journal of the American Geriatrics Society, 55:S128–29. BLACKWELL PUBLISHING, 2007.Link to Item
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Aaberg, T., A. Rolon, and S. W. Cousins. “Nitric oxide and lens-associated uveitis (LAU).” In Investigative Ophthalmology and Visual Science, Vol. 38, 1997.
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Morales, P. H., E. Hernandez, A. Rolon, and S. W. Cousins. “Laser photocoagulation increases PVR severity.” In Investigative Ophthalmology and Visual Science, Vol. 38, 1997.
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Wang, X. C., D. C. S. Yang, and S. W. Cousins. “Intravitrealsubstained-releasecyclosporjne a (CsA) inthh treatment of experimental uveitis.” In Investigative Ophthalmology and Visual Science, Vol. 38, 1997.
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Wang, X. C., D. C. S. Yang, S. W. Cousins, R. P. Gallemore, P. Ashton, and G. J. Jaffe. “Intravitreal sustained-release cyclosporine A (CsA) in the treatment of experimental uveitis.” In Investigative Ophthalmology & Visual Science, 38:1016–1016. LIPPINCOTT-RAVEN PUBL, 1997.Link to Item
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Cousins, S. W., and X. K. Lui. “Diminished ocular tgf-β2 concentration and mrna levels during ocular inflammation correlate with severity of disease.” In Faseb Journal, Vol. 10, 1996.
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Dix, R. D., M. Giedlin, and S. W. Cousins. “Cytokine immunotherapy for cytomegalovirus retinitis in mice with maids.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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Rolon, A., and S. W. Cousins. “Role of T cells in bacteria-induced Lens-Associated Uveitis (LAU).” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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Rosenbaum, J. T., and S. W. Cousins. “Endotoxin induced ocular vascular permeability as a model to study the pathogenesis of Reiter's syndrome.” In Arthritis and Rheumatism, 24:34, 1981.
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