Scholars@Duke
Seth Teplitsky

Seth Teplitsky

Provisional Faculty in the Department of Urology
Urology

Selected Publications

Prognostic significance of pathologic response to neoadjuvant chemotherapy in muscle-invasive urothelial carcinoma of the bladder with histologic subtype.

Journal Article Urol Oncol · September 2025 INTRODUCTION: Patients with histologic subtypes (HS) of urothelial cancers are often excluded from neoadjuvant chemotherapy (NAC) trials for muscle-invasive bladder cancer (MIBC). Additionally, there exist conflicting data regarding the inherent chemothera ... Full text Link to item Cite

Disruptive papers - A novel bibliometric tool not yet ready for primetime in pediatric urology.

Journal Article J Pediatr Urol · April 2025 BACKGROUND: Historically, word of mouth, total citation count, H-index, and expert opinion were some of the primary metrics used to identify the most influential papers. This method is subject to significant bias. The disruption score was initially created ... Full text Link to item Cite

Operative duration as independent predictor of increased postoperative healthcare utilization.

Journal Article Int Urol Nephrol · January 2024 PURPOSE: Few studies have examined the risk factors for postoperative healthcare resource utilization (HRU) among minimally invasive partial nephrectomy (MIPN), minimally invasive prostatectomy (MIP), and cystectomy (Cx). The aim of this study is to assess ... Full text Link to item Cite

Editorial Comment.

Journal Article Urol Pract · September 2023 Full text Link to item Cite

"Exogenous" 5 Alpha Reductase Deficiency: A Case Report.

Journal Article Urology · August 2023 Testosterone and dihydrotestosterone are significant drivers of male external genital development, and therefore teratogens that alter these hormone profiles have been hypothesized to cause aberrations in development. Here, we present the first case report ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · July 2023 Full text Link to item Cite

Investigation of urology intraoperative events leading to root cause analysis at national VA medical centers.

Journal Article Can J Urol · April 2023 INTRODUCTION: Adverse events in urologic procedures are poorly studied. This study analyzes the Veterans Health Administration (VHA) Root Cause Analysis (RCA) data for patient safety adverse events during urologic procedures performed in a VHA operating ro ... Link to item Cite

Burnout: A Call to Action From the AUA Workforce Workgroup.

Journal Article J Urol · March 2023 PURPOSE: We hypothesize burnout has failed to improve and certain demographics may be disproportionately affected. MATERIALS AND METHODS: The AUA Workforce Workgroup examined work from the annual AUA Census over the past several years. Particular to this s ... Full text Link to item Cite

Urinary undiversion by conversion of the incontinent ileovesicostomy to augmentation ileocystoplasty in spinal cord injured patients.

Journal Article J Spinal Cord Med · July 2022 Context: Spinal cord injury (SCI) patients with neurogenic bladder and the inability to self-catheterize may require incontinent diversion to provide low-pressure drainage while avoiding the use of indwelling catheters. We demonstrate that in patients with ... Full text Link to item Cite

Operative duration and short term morbidity and mortality following radical cystectomy with urinary diversion.

Journal Article Can J Urol · April 2022 INTRODUCTION: To elucidate the association between operative duration (OD) and postoperative complications, which has been poorly studied in radical cystectomy. We hypothesize an increase in morbidity in radical cystectomy cases which have a longer OD. MAT ... Link to item Cite

Incidental prostate cancer at holmium laser enucleation of prostate.

Journal Article Can J Urol · December 2021 INTRODUCTION: The purpose of this study was to describe the current incidence, risk factors, and management of incidental diagnosis of prostate cancer (iPCa) among patients who underwent holmium laser enucleation of prostate (HoLEP) and have no history of ... Link to item Cite

Diagnosis of advanced prostate cancer at the community level in Rwanda.

Journal Article Int Urol Nephrol · October 2021 BACKGROUND: Prostate cancer is the second most common cancer in men and sixth leading cause of mortality. If not recognized early, patients with advanced prostate cancer can experience debilitating complications which can otherwise be prevented by early an ... Full text Link to item Cite

Setting the Standards: Examining Research Productivity Among Academic Urologists in the USA and Canada in 2019.

Journal Article Eur Urol Focus · March 2021 BACKGROUND: Research productivity among academic urologists is strongly encouraged, but little data are available on productivity metrics within the field. OBJECTIVE: To provide the first comprehensive survey of research productivity among academic urologi ... Full text Link to item Cite

Perspectives and Experiences of Transgender and Non-binary Individuals on Seeking Urological Care.

Journal Article Urology · February 2021 OBJECTIVE: To describe perspectives and experiences related to urology care-seeking of transgender and non-binary (TGNB) individuals assigned male at birth. MATERIALS AND METHODS: This HIPAA-compliant study was IRB approved and followed Consolidated Criter ... Full text Link to item Cite

Ergonomics in Endourology: Measurement of Force for Deflection in Contemporary Ureteroscopes.

Journal Article J Endourol · February 2021 Introduction: Few studies have examined the ergonomic hazards to endourologists during endoscopic procedures. We have evaluated the forces required to deflect different flexible ureteroscopes across a range of measurements with several different standard i ... Full text Link to item Cite

How I Do It: Anticoagulation management for common urologic procedures.

Journal Article Can J Urol · December 2020 Appropriate perioperative management of antithrombotic medications is critical; for every patient, the risk of bleeding must be balanced against individual risk of thrombosis. There has been a rapid influx of new antithrombotic therapies in the past 5 year ... Link to item Cite

Next-generation DNA sequencing for infected genitourinary implants: How I do it.

Journal Article Can J Urol · October 2020 Infection of artificial urinary sphincters or inflatable penile prostheses is one of the most devastating complications after prosthetic surgery and can have a significant impact on a quality of life. Patients undergoing revision surgery with or without de ... Link to item Cite

Iatrogenic bladder rupture in individuals with disability related to spinal cord injury and chronic indwelling urethral catheters.

Journal Article Spinal Cord Ser Cases · June 8, 2020 INTRODUCTION: Bladder rupture in patients with indwelling urethral catheters is rare. Herein, we describe two spinal cord injured (SCI) patients with neurogenic bladder dysfunction managed with chronic indwelling catheters who presented with extraperitonea ... Full text Link to item Cite

Industry payments to female pelvic medicine and reconstructive surgeons: an analysis of Sunshine Act open payments from 2014-2017.

Journal Article Int Urogynecol J · April 2020 INTRODUCTION AND HYPOTHESIS: We aim to examine the financial relationship between industry and female pelvic medicine and reconstructive surgeons (FPMRS) during the first four full calendar years since the implementation of the Sunshine Act. METHODS: All b ... Full text Link to item Cite

Impact of Tumor Regional Involvement on Active Surveillance Outcomes: Validation of the Cumulative Cancer Location Metric in a US Population.

Journal Article Eur Urol Focus · March 15, 2020 BACKGROUND: Treatment progression for men on active surveillance (AS) for prostate cancer (PCa) is driven primarily by grade and volume progression on isolated prostate biopsies (PBx). As PCa is a multifocal disease, regional disease progression over time ... Full text Link to item Cite

Questioning the Status Quo: Should Gleason Grade Group 1 Prostate Cancer be Considered a "Negative Core" in Pre-Radical Prostatectomy Risk Nomograms? An International Multicenter Analysis.

Journal Article Urology · March 2020 OBJECTIVE: To assess the impact of excluding Gleason Grade Group 1 (GG1) prostate cancer (CaP) cores from current pre-radical prostatectomy (RP) nomograms. METHODS: Multi-institutional retrospective chart review was performed on all RP patients with prosta ... Full text Link to item Cite

Twitter and academic Urology in the United States and Canada: a comprehensive assessment of the Twitterverse in 2019.

Journal Article BJU Int · January 2020 OBJECTIVE: To provide the first comprehensive analysis of the Twitterverse amongst academic urologists and programmes in North America. METHODS: Using national accreditation and individual programme websites, all active urology residency programmes (USA an ... Full text Link to item Cite

An Assessment of an Outpatient Urology Clinic's Compassion, Comfort and Knowledge of Transgender Care.

Journal Article Urol Pract · January 2020 INTRODUCTION: Transgender patients face significant barriers to care, including providers who lack compassion, comfort and knowledge. We assessed the preparedness of an outpatient urology clinic in caring for transgender patients by administering a questio ... Full text Link to item Cite

Stress Urinary Incontinence post-Holmium Laser Enucleation of the Prostate: a Single-Surgeon Experience.

Journal Article Int Braz J Urol · 2020 PURPOSE: To identify incidence and predictors of stress urinary incontinence (SUI) following Holmium laser enucleation of the prostate (HoLEP). MATERIALS AND METHODS: We performed a retrospective review of 589 HoLEP patients from 2012-2018. Patients were a ... Full text Link to item Cite

Medical evaluation and management of male and female voiding dysfunction: a review.

Journal Article Rom J Intern Med · September 1, 2019 A significant workforce shortage of urologists available to serve the US population has been projected to occur over the next decade. Accordingly, much of the management of urologic patients will need to be assumed by other specialties and practitioners. S ... Full text Link to item Cite

A retrospective comparison of diode to holmium for laser enucleation of the prostate.

Journal Article Can J Urol · August 2019 INTRODUCTION: Holmium endoscopic laser enucleation of the prostate (HoLEP) is a well-established alternative to traditional transurethral resection and open prostatectomy for the treatment of benign prostatic hyperplasia (BPH). We investigate the 1470 nm d ... Link to item Cite

Aquablation of the prostate: a review and update.

Journal Article Can J Urol · August 2019 INTRODUCTION: Invasive procedures, such as transurethral resection of the prostate (TURP), have long been the gold standard therapy for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). In recent years, n ... Link to item Cite

Holmium laser enucleation of the prostate (HoLEP): a review and update.

Journal Article Can J Urol · August 2019 INTRODUCTION: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) is one of the most common diseases affecting the aging man, with almost 80% of men greater than 70 affected. Historically, transurethral resection of the pros ... Link to item Cite

Medial Renal Ptosis: First Radiographic Documentation With Computed Tomography.

Journal Article Urology · April 2019 Medial renal ptosis is the abnormal mobility of the kidney towards or across the midline of the body. Historically, this phenomenon is evaluated by observing abnormal mobility in the lateral decubitus position during intravenous pyelography. Here, we prese ... Full text Link to item Cite

Knowledge Gaps in Urologic Care of Female Spinal Cord Injury Patients.

Journal Article Curr Urol Rep · March 23, 2019 PURPOSE OF REVIEW: We highlight the substantial gaps in knowledge on urologic care of female spinal cord injury (SCI) patients. RECENT FINDINGS: Males account for approximately 80% of people living with SCI in developed nations. Although there is a robust ... Full text Link to item Cite

Incorporating mpMRI biopsy data into established pre-RP nomograms: potential impact of an increasingly common clinical scenario.

Journal Article Ther Adv Urol · 2019 BACKGROUND: We examine the practical application of multiparametric MRI (mpMRI) prostate biopsy data using established pre-RP nomograms and its potential implications on RP intraoperative decision-making. We hypothesize that current nomograms are suboptima ... Full text Link to item Cite

Rectourethral fistula: a rare complication after HoLEP.

Journal Article Can J Urol · December 2018 We report a rare complication of rectourethral fistula formation 6 weeks after a 70-year-old man underwent an uneventful HoLEP procedure. Cystourethrogram confirmed the diagnosis and the patient was managed conservatively with chronic indwelling catheter p ... Link to item Cite

Lymph node imaging in testicular cancer.

Journal Article Transl Androl Urol · October 2018 Testicular cancer is a rare malignancy mainly affecting young men. Survival for testicular cancer remains high due to the effectiveness of multimodal treatment options. Accurate imaging is imperative to both treatment and follow-up. Both computed tomograph ... Full text Link to item Cite

Short-term Outcomes of Total Knee Arthroplasty Performed at an Orthopedic Specialty Hospital.

Journal Article Orthopedics · January 1, 2018 This study compared perioperative outcomes for total knee arthroplasty (TKA) at an orthopedic specialty hospital and a tertiary referral center. The authors identified all primary TKA procedures performed in 2014 at the 2 facilities. Each patient at the or ... Full text Link to item Cite

Dorsal versus lateral plate fixation of finger proximal phalangeal fractures: a retrospective study.

Journal Article Arch Orthop Trauma Surg · April 2017 INTRODUCTION: Unstable proximal phalanx fractures are relatively common injuries but consensus of standard treatment is lacking. Outcomes following plate fixation are highly variable, and it remains unclear which factors are predictive for poorer results. ... Full text Link to item Cite

Glutamate oxaloacetate transaminase enables anaplerotic refilling of TCA cycle intermediates in stroke-affected brain.

Journal Article FASEB J · April 2017 Ischemic stroke results in excessive release of glutamate, which contributes to neuronal cell death. Here, we test the hypothesis that otherwise neurotoxic glutamate can be productively metabolized by glutamate oxaloacetate transaminase (GOT) to maintain c ... Full text Link to item Cite

Robot-assisted mechanical therapy attenuates stroke-induced limb skeletal muscle injury.

Journal Article FASEB J · March 2017 The efficacy and optimization of poststroke physical therapy paradigms is challenged in part by a lack of objective tools available to researchers for systematic preclinical testing. This work represents a maiden effort to develop a robot-assisted mechanic ... Full text Link to item Cite

Photoperiodic Regulation of Cerebral Blood Flow in White-Footed Mice (Peromyscus leucopus).

Journal Article eNeuro · 2016 Individuals living outside the tropics need to adjust their behavioral and physiological repertoires throughout the year to adapt to the changing seasons. White-footed mice (Peromyscus leucopus) reduce hippocampal volumes, hippocampal-dependent memory func ... Full text Link to item Cite

Excessive α-tocopherol exacerbates microglial activation and brain injury caused by acute ischemic stroke.

Journal Article FASEB J · March 2015 The vitamin E family includes both tocopherols and tocotrienols, where α-tocopherol (αTOC) is the most bioavailable form. Clinical trials testing the therapeutic efficacy of high-dose αTOC against stroke have largely failed or reported negative outcomes wh ... Full text Link to item Cite