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Shannon Jones McCall

Associate Professor of Pathology
Pathology
Duke Box 3712, Room 309 Davison Bldg, Durham, NC 27710
Dept of Pathology Box 3712, Room 309 Davison Building, Durham, NC 27710

Overview


As Vice Chair for Translational Research in the Department of Pathology, I am involved in numerous translational cancer research projects that rely on the study of human biological samples.  I am the director of the Duke BioRepository & Precision Pathology Center (Duke BRPC), a shared resource of the School of Medicine and the Duke Cancer Institute.  I serve as the PI for the National Cancer Institute's Cooperative Human Tissue Network Southern Division (a five-year UM1 grant), which lives in the Duke BRPC.  My own area of research interest is gastrointestinal tract metaplasias and their relationship to carcinogenesis, particularly in the upper GI tract.

Current Appointments & Affiliations


Associate Professor of Pathology · 2020 - Present Pathology, Clinical Science Departments
Associate Professor in Surgery · 2020 - Present Surgery, Surgical Sciences, Surgery
Member of the Duke Cancer Institute · 2017 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published July 31, 2017
X-ray diffraction spectra classify breast tissue
Published January 4, 2017
Medical Xpress: Study sheds light on esophageal cancer
Published December 21, 2016
New breast cancer therapy targets common genetic mutation

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Recent Publications


The College of American Pathologists Biorepository Accreditation Program: Results from the First 10 Years.

Journal Article Biopreserv Biobank · February 19, 2026 INTRODUCTION: The College of American Pathologists (CAP) Biorepository Accreditation Program (BAP) was established in 2012 with the goal of providing standardized requirements that ensure high quality for procuring, processing, storing, distributing, and c ... Full text Link to item Cite

Prognostic Implications of Codon-Specific KRAS Mutations in Localized and Advanced Stages of Pancreatic Cancer.

Journal Article JCO Precis Oncol · February 2026 PURPOSE: Although KRAS mutations represent the primary oncogenic driver in pancreatic ductal adenocarcinoma (PDAC), the association between codon-specific alterations and patient outcomes remains poorly elucidated, largely because of a lack of data sets co ... Full text Link to item Cite

Iron Deficiency Anemia is Associated With Gastric Intestinal Metaplasia in Patients With Helicobacter pylori Infection.

Journal Article Gastro Hep Adv · 2026 BACKGROUND AND AIMS: Despite acknowledgment of the relationship between iron deficiency anemia (IDA) and Helicobacter pylori, consensus is lacking on clinical practice implications. This study sought to examine the association of iron deficiency and anemia ... Full text Link to item Cite
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Recent Grants


Cooperative Human Tissue Network Support through Duke's BioRepository & Precision Pathology Center

ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2019 - 2029

Therapeutic intervention to reverse gastric precancer

Clinical TrialCo Investigator · Awarded by Department of Defense · 2024 - 2028

IMAGINE: Intestinal Metaplasia And Gastritis INtErception Study

ResearchPathologist · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028

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Education


Duke University · 2000 M.D.
North Carolina State University · 1996 B.S.