Shelley R McDonald | Scholars@Duke

Shelley R McDonald
Associate Professor of Medicine

Current Appointments & Affiliations

Associate Professor of Medicine, Medicine, Geriatrics, Medicine 2021
Senior Fellow of the Center for the Study of Aging and Human Development, Center for the Study of Aging and Human Development, Institutes and Centers 2020

Contact Information

Box 3003, DUMC, Durham, NC 27710
Box 3003, DUMC, Durham, NC 27710
shelley.mcdonald@duke.edu (919) 660-7513

Background
Education, Training, & Certifications
- Resident, Internal Medicine, Scott and White Memorial Hospital 2004 - 2007
- D.O./Ph.D., University of North Texas Health Science Center, Fort Worth 2004
Duke Appointment History
- Assistant Professor of Medicine, Medicine, Geriatrics, Medicine 2014 - 2021
Research
Selected Grants
- Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative) awarded by National Institutes of Health 2017 - 2022
- Effects of Blueberry Extract on Physical Activity, Vascular Function and Cognition in Sedentary Older Adults awarded by U.S. Highbush Blueberry Council 2019 - 2021
- An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition awarded by Dairy Management, Inc. 2015 - 2020
- John A. Hartford Foundation's Centers of Excellence (CoE) awarded by John A. Hartford Foundation, Inc. 2015 - 2016
- A High-Protein Weight Loss Treatment for Sarcopenic Obesity awarded by National Pork Board 2013 - 2015
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Pernik, Mark N., Palvasha R. Deme, Madelina L. Nguyen, Salah G. Aoun, Owoicho Adogwa, Kristen Hall, Nick A. Stewart, et al. “Perioperative Optimization of Senior Health in Spine Surgery: Impact on Postoperative Delirium.” J Am Geriatr Soc 69, no. 5 (May 2021): 1240–48. https://doi.org/10.1111/jgs.17006.
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  - Miller, Marshall G., Kathryn N. Porter Starr, Jamie Rincker, Melissa C. Orenduff, Shelley R. McDonald, Carl F. Pieper, Angela R. Fruik, Kenneth W. Lyles, and Connie W. Bales. “Rationale and Design for a Higher (Dairy) Protein Weight Loss Intervention That Promotes Muscle Quality and Bone Health in Older Adults with Obesity: A Randomized, Controlled Pilot Study.” J Nutr Gerontol Geriatr 40, no. 2–3 (April 2021): 150–70. https://doi.org/10.1080/21551197.2021.1896615.
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  - Grimberg, Dominic C., Ankeet Shah, Jeroen Molinger, John Whittle, Rajan T. Gupta, Paul E. Wischmeyer, Shelley R. McDonald, and Brant A. Inman. “Assessments of frailty in bladder cancer.” Urol Oncol 38, no. 9 (September 2020): 698–705. https://doi.org/10.1016/j.urolonc.2020.04.036.
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  - McDonald, Shelley R., Atilio Barbeito, and Sandhya A. Lagoo-Deenadayalan. “Reframing Surgical Risk Using Geriatric Assessment Measures.” Jama Surg 155, no. 5 (May 1, 2020): 418–19. https://doi.org/10.1001/jamasurg.2020.0092.
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  - McDonald, Shelley R., Mitchell T. Heflin, and Sandhya A. Lagoo-Deenadayalan. “Care Redesign for Emergency General Surgery in Older Adults.” Jama Surg 155, no. 4 (April 1, 2020): e196022. https://doi.org/10.1001/jamasurg.2019.6022.
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  - Wong, Serena P., Kahli M. Zietlow, Shelley R. McDonald, Atilio Barbeito, Cathleen S. Colon-Emeric, Sandhya A. Lagoo-Deenadayalan, Nancy Loyack, and Mitchell T. Heflin. “Delaying Elective Surgery in Geriatric Patients: An Opportunity for Preoperative Optimization.” Anesth Analg 130, no. 1 (January 2020): e14–18. https://doi.org/10.1213/ANE.0000000000004335.
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  - VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.
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  - Porter Starr, Kathryn N., Margery A. Connelly, Melissa C. Orenduff, Shelley R. McDonald, Richard Sloane, Kim M. Huffman, William E. Kraus, and Connie W. Bales. “Impact on cardiometabolic risk of a weight loss intervention with higher protein from lean red meat: Combined results of 2 randomized controlled trials in obese middle-aged and older adults.” J Clin Lipidol 13, no. 6 (November 2019): 920–31. https://doi.org/10.1016/j.jacl.2019.09.012.
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  - Qassamali, Sonia R., Sandhya Lagoo-Deenadayalan, Shelley McDonald, Brett Morgan, and Victoria Goode. “The importance of the STOP- BANG questionnaire as a preoperative assessment tool for the elderly population.” Geriatr Nurs 40, no. 5 (September 2019): 536–39. https://doi.org/10.1016/j.gerinurse.2019.08.010.
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  - Sharda, Neema, Emily Mattoon, Loretta Matters, Judy Prewitt, Shelley McDonald, Richard Sloane, Christy Cassas, and Heidi White. “Bach to the Basics: Implementation and Impact of a Postoperative, Inpatient Personalized Music Program for Older Adults.” J Perianesth Nurs 34, no. 2 (April 2019): 347–53. https://doi.org/10.1016/j.jopan.2018.05.006.
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  - Porter Starr, Kathryn N., Melissa Orenduff, Shelley R. McDonald, Hillary Mulder, Richard Sloane, Carl F. Pieper, and Connie W. Bales. “Influence of Weight Reduction and Enhanced Protein Intake on Biomarkers of Inflammation in Older Adults with Obesity.” J Nutr Gerontol Geriatr 38, no. 1 (January 2019): 33–49. https://doi.org/10.1080/21551197.2018.1564200.
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  - Corey, Kristin M., Sehj Kashyap, Elizabeth Lorenzi, Sandhya A. Lagoo-Deenadayalan, Katherine Heller, Krista Whalen, Suresh Balu, et al. “Development and validation of machine learning models to identify high-risk surgical patients using automatically curated electronic health record data (Pythia): A retrospective, single-site study.” Plos Med 15, no. 11 (November 2018): e1002701. https://doi.org/10.1371/journal.pmed.1002701.
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  - McDonald, Shelley R., Mitchell T. Heflin, Heather E. Whitson, Thomas O. Dalton, Michael E. Lidsky, Phillip Liu, Cornelia M. Poer, et al. “Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative.” Jama Surg 153, no. 5 (May 1, 2018): 454–62. https://doi.org/10.1001/jamasurg.2017.5513.
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  - Porter Starr, Kathryn N., Shelley R. McDonald, Aubrey Jarman, Melissa Orenduff, Richard Sloane, Carl F. Pieper, and Connie W. Bales. “Markers of Renal Function in Older Adults Completing a Higher Protein Obesity Intervention and One Year Later: Findings from the MEASUR-UP Trial.” J Nutr Gerontol Geriatr 37, no. 2 (April 2018): 117–29. https://doi.org/10.1080/21551197.2018.1478696.
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  - Zietlow, Kahli, Shelley R. McDonald, Richard Sloane, Jeffrey Browndyke, Sandhya Lagoo-Deenadayalan, and Mitchell T. Heflin. “Preoperative Cognitive Impairment As a Predictor of Postoperative Outcomes in a Collaborative Care Model.” J Am Geriatr Soc 66, no. 3 (March 2018): 584–89. https://doi.org/10.1111/jgs.15261.
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  - Marwell, Julianna G., Mitchell T. Heflin, and Shelley R. McDonald. “Preoperative Screening.” Clin Geriatr Med 34, no. 1 (February 2018): 95–105. https://doi.org/10.1016/j.cger.2017.08.004.
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  - Payne, M. E., K. N. Porter Starr, M. Orenduff, H. S. Mulder, S. R. McDonald, A. P. Spira, C. F. Pieper, and C. W. Bales. “Quality of Life and Mental Health in Older Adults with Obesity and Frailty: Associations with a Weight Loss Intervention.” J Nutr Health Aging 22, no. 10 (2018): 1259–65. https://doi.org/10.1007/s12603-018-1127-0.
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  - Bales, Connie W., Kathryn N. Porter Starr, Melissa C. Orenduff, Shelley R. McDonald, Karen Molnar, Aubrey K. Jarman, Ann Onyenwoke, Hillary Mulder, Martha E. Payne, and Carl F. Pieper. “Influence of Protein Intake, Race, and Age on Responses to a Weight-Reduction Intervention in Obese Women.” Curr Dev Nutr 1, no. 5 (May 1, 2017). https://doi.org/10.3945/cdn.117.000703.
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  - Porter Starr, Kathryn N., Carl F. Pieper, Melissa C. Orenduff, Shelley R. McDonald, Luisa B. McClure, Run Zhou, Martha E. Payne, and Connie W. Bales. “Improved Function With Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail, Obese Older Adults.” J Gerontol a Biol Sci Med Sci 71, no. 10 (October 2016): 1369–75. https://doi.org/10.1093/gerona/glv210.
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  - Adam, M. A., S. McDonald, M. Heflin, and S. Lagoo-Deenadayalan. “Incorporating shared decision making into perioperative care of older adults.” Current Surgery Reports 4, no. 8 (August 1, 2016). https://doi.org/10.1007/s40137-016-0148-z.
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  - Porter Starr, Kathryn N., Shelley R. McDonald, Julia A. Weidner, and Connie W. Bales. “Challenges in the Management of Geriatric Obesity in High Risk Populations.” Nutrients 8, no. 5 (May 4, 2016). https://doi.org/10.3390/nu8050262.
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  - McDonald, Shelley R., and Mitchell T. Heflin. “Update on preoperative assessment for geriatric patients prior to elective surgery.” Geriatr Nurs 37, no. 2 (March 2016): 160–62. https://doi.org/10.1016/j.gerinurse.2016.02.005.
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  - Porter Starr, Kathryn N., Shelley R. McDonald, and Connie W. Bales. “Nutritional Vulnerability in Older Adults: A Continuum of Concerns.” Curr Nutr Rep 4, no. 2 (June 2015): 176–84. https://doi.org/10.1007/s13668-015-0118-6.
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  - McDonald, Shelley R., Kathryn N. Porter Starr, Luisa Mauceri, Melissa Orenduff, Esther Granville, Christine Ocampo, Martha E. Payne, Carl F. Pieper, and Connie W. Bales. “Meal-based enhancement of protein quality and quantity during weight loss in obese older adults with mobility limitations: rationale and design for the MEASUR-UP trial.” Contemp Clin Trials 40 (January 2015): 112–23. https://doi.org/10.1016/j.cct.2014.11.010.
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  - Porter Starr, Kathryn N., Shelley R. McDonald, and Connie W. Bales. “Obesity and physical frailty in older adults: a scoping review of lifestyle intervention trials.” J Am Med Dir Assoc 15, no. 4 (April 2014): 240–50. https://doi.org/10.1016/j.jamda.2013.11.008.
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  - McDonald, Shelley R., Rajindar S. Sohal, and Michael J. Forster. “Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice.” Free Radic Biol Med 38, no. 6 (March 15, 2005): 729–36. https://doi.org/10.1016/j.freeradbiomed.2004.11.014.
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  - McDonald, S. R., and M. J. Forster. “Lifelong vitamin E intake retards age-associated decline of spatial learning ability in apoE-deficient mice.” Age 27, no. 1 (March 1, 2005): 5–16. https://doi.org/10.1007/s11357-005-4003-x.
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  - Choi, Joungil, Michael J. Forster, Shelley R. McDonald, Susan T. Weintraub, Christopher A. Carroll, and Robert W. Gracy. “Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease.” Free Radic Biol Med 36, no. 9 (May 1, 2004): 1155–62. https://doi.org/10.1016/j.freeradbiomed.2004.02.002.
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- Conference Papers
  - Zietlow, Kahli E., Serena Wong, Shelley R. McDonald, Cathleen Colón-Emeric, Christy Cassas, Sandhya Lagoo-Deenadayalan, and Mitchell T. Heflin. “Perioperative Optimization of Senior Health (POSH): A Descriptive Analysis of Cancelled Surgery.” In World J Surg, 45:109–15, 2021. https://doi.org/10.1007/s00268-020-05772-z.
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  - Zietlow, Kahli E., Deborah M. Oyeyemi, Sarah E. Cook, Margaret Hardy, Shelley R. McDonald, Sandhya Lagoo-Deenadayalan, Mitchell T. Heflin, and Heather E. Whitson. “RESEARCHCognition and Capacity to Consent for Elective Surgery.” In J Am Geriatr Soc, 68:2694–96, 2020. https://doi.org/10.1111/jgs.16786.
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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles

Conference Papers