Shelley R McDonald
Associate Professor of Medicine
Current Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Geriatrics, Medicine 2021
- Senior Fellow of the Center for the Study of Aging and Human Development, Center for the Study of Aging and Human Development, Institutes and Centers 2020
Contact Information
- Box 3003, DUMC, Durham, NC 27710
- Box 3003, DUMC, Durham, NC 27710
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shelley.mcdonald@duke.edu
(919) 660-7513
- Background
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Education, Training, & Certifications
- Resident, Internal Medicine, Scott and White Memorial Hospital 2004 - 2007
- D.O./Ph.D., University of North Texas Health Science Center, Fort Worth 2004
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Previous Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Geriatrics, Medicine 2014 - 2021
- Research
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Selected Grants
- Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative) awarded by National Institutes of Health 2017 - 2022
- Effects of Blueberry Extract on Physical Activity, Vascular Function and Cognition in Sedentary Older Adults awarded by U.S. Highbush Blueberry Council 2019 - 2022
- An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition awarded by Dairy Management, Inc. 2015 - 2020
- John A. Hartford Foundation's Centers of Excellence (CoE) awarded by John A. Hartford Foundation, Inc. 2015 - 2016
- A High-Protein Weight Loss Treatment for Sarcopenic Obesity awarded by National Pork Board 2013 - 2015
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External Relationships
- Pfizer Inc.
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Kazaure, Hadiza S., Shelley R. McDonald, and Sandhya A. Lagoo-Deenadayalan. “A Sobering Tale of Missed Opportunities for Advance Care Planning-Now Is the Time for Action.” Jama Surg 157, no. 10 (October 1, 2022): e223693. https://doi.org/10.1001/jamasurg.2022.3693.Full Text Link to Item
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Cooter Wright, Mary, Thomas Bunning, Sarada S. Eleswarpu, Mitchell T. Heflin, Shelley R. McDonald, Sandhya Lagoo-Deenadalayan, Heather E. Whitson, Pablo Martinez-Camblor, Stacie G. Deiner, and Miles Berger. “A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study.” Anesth Analg 134, no. 1 (January 1, 2022): 149–58. https://doi.org/10.1213/ANE.0000000000005660.Full Text Link to Item
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Zietlow, Kahli E., Serena Wong, Mitchell T. Heflin, Shelley R. McDonald, Robert Sickeler, Michael Devinney, Jeanna Blitz, Sandhya Lagoo-Deenadayalan, and Miles Berger. “Geriatric Preoperative Optimization: A Review.” Am J Med 135, no. 1 (January 2022): 39–48. https://doi.org/10.1016/j.amjmed.2021.07.028.Full Text Link to Item
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Pernik, Mark N., Palvasha R. Deme, Madelina L. Nguyen, Salah G. Aoun, Owoicho Adogwa, Kristen Hall, Nick A. Stewart, et al. “Perioperative Optimization of Senior Health in Spine Surgery: Impact on Postoperative Delirium.” J Am Geriatr Soc 69, no. 5 (May 2021): 1240–48. https://doi.org/10.1111/jgs.17006.Full Text Link to Item
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Miller, Marshall G., Kathryn N. Porter Starr, Jamie Rincker, Melissa C. Orenduff, Shelley R. McDonald, Carl F. Pieper, Angela R. Fruik, Kenneth W. Lyles, and Connie W. Bales. “Rationale and Design for a Higher (Dairy) Protein Weight Loss Intervention That Promotes Muscle Quality and Bone Health in Older Adults with Obesity: A Randomized, Controlled Pilot Study.” J Nutr Gerontol Geriatr 40, no. 2–3 (2021): 150–70. https://doi.org/10.1080/21551197.2021.1896615.Full Text Link to Item
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Grimberg, Dominic C., Ankeet Shah, Jeroen Molinger, John Whittle, Rajan T. Gupta, Paul E. Wischmeyer, Shelley R. McDonald, and Brant A. Inman. “Assessments of frailty in bladder cancer.” Urol Oncol 38, no. 9 (September 2020): 698–705. https://doi.org/10.1016/j.urolonc.2020.04.036.Full Text Open Access Copy Link to Item
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McDonald, Shelley R., Atilio Barbeito, and Sandhya A. Lagoo-Deenadayalan. “Reframing Surgical Risk Using Geriatric Assessment Measures.” Jama Surg 155, no. 5 (May 1, 2020): 418–19. https://doi.org/10.1001/jamasurg.2020.0092.Full Text Link to Item
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McDonald, Shelley R., Mitchell T. Heflin, and Sandhya A. Lagoo-Deenadayalan. “Care Redesign for Emergency General Surgery in Older Adults.” Jama Surg 155, no. 4 (April 1, 2020): e196022. https://doi.org/10.1001/jamasurg.2019.6022.Full Text Link to Item
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Wong, Serena P., Kahli M. Zietlow, Shelley R. McDonald, Atilio Barbeito, Cathleen S. Colon-Emeric, Sandhya A. Lagoo-Deenadayalan, Nancy Loyack, and Mitchell T. Heflin. “Delaying Elective Surgery in Geriatric Patients: An Opportunity for Preoperative Optimization.” Anesth Analg 130, no. 1 (January 2020): e14–18. https://doi.org/10.1213/ANE.0000000000004335.Full Text Open Access Copy Link to Item
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VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.Full Text Open Access Copy Link to Item
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Sharda, Neema, Emily Mattoon, Loretta Matters, Judy Prewitt, Shelley McDonald, Richard Sloane, Christy Cassas, and Heidi White. “Bach to the Basics: Implementation and Impact of a Postoperative, Inpatient Personalized Music Program for Older Adults.” J Perianesth Nurs 34, no. 2 (April 2019): 347–53. https://doi.org/10.1016/j.jopan.2018.05.006.Full Text Link to Item
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Porter Starr, Kathryn N., Margery A. Connelly, Melissa C. Orenduff, Shelley R. McDonald, Richard Sloane, Kim M. Huffman, William E. Kraus, and Connie W. Bales. “Impact on cardiometabolic risk of a weight loss intervention with higher protein from lean red meat: Combined results of 2 randomized controlled trials in obese middle-aged and older adults.” J Clin Lipidol 13, no. 6 (2019): 920–31. https://doi.org/10.1016/j.jacl.2019.09.012.Full Text Link to Item
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Porter Starr, Kathryn N., Melissa Orenduff, Shelley R. McDonald, Hillary Mulder, Richard Sloane, Carl F. Pieper, and Connie W. Bales. “Influence of Weight Reduction and Enhanced Protein Intake on Biomarkers of Inflammation in Older Adults with Obesity.” J Nutr Gerontol Geriatr 38, no. 1 (2019): 33–49. https://doi.org/10.1080/21551197.2018.1564200.Full Text Link to Item
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Qassamali, Sonia R., Sandhya Lagoo-Deenadayalan, Shelley McDonald, Brett Morgan, and Victoria Goode. “The importance of the STOP- BANG questionnaire as a preoperative assessment tool for the elderly population.” Geriatr Nurs 40, no. 5 (2019): 536–39. https://doi.org/10.1016/j.gerinurse.2019.08.010.Full Text Link to Item
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Corey, Kristin M., Sehj Kashyap, Elizabeth Lorenzi, Sandhya A. Lagoo-Deenadayalan, Katherine Heller, Krista Whalen, Suresh Balu, et al. “Development and validation of machine learning models to identify high-risk surgical patients using automatically curated electronic health record data (Pythia): A retrospective, single-site study.” Plos Med 15, no. 11 (November 2018): e1002701. https://doi.org/10.1371/journal.pmed.1002701.Full Text Link to Item
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McDonald, Shelley R., Mitchell T. Heflin, Heather E. Whitson, Thomas O. Dalton, Michael E. Lidsky, Phillip Liu, Cornelia M. Poer, et al. “Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative.” Jama Surg 153, no. 5 (May 1, 2018): 454–62. https://doi.org/10.1001/jamasurg.2017.5513.Full Text Link to Item
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Zietlow, Kahli, Shelley R. McDonald, Richard Sloane, Jeffrey Browndyke, Sandhya Lagoo-Deenadayalan, and Mitchell T. Heflin. “Preoperative Cognitive Impairment As a Predictor of Postoperative Outcomes in a Collaborative Care Model.” J Am Geriatr Soc 66, no. 3 (March 2018): 584–89. https://doi.org/10.1111/jgs.15261.Full Text Open Access Copy Link to Item
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Marwell, Julianna G., Mitchell T. Heflin, and Shelley R. McDonald. “Preoperative Screening.” Clin Geriatr Med 34, no. 1 (February 2018): 95–105. https://doi.org/10.1016/j.cger.2017.08.004.Full Text Link to Item
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Payne, M. E., K. N. Porter Starr, M. Orenduff, H. S. Mulder, S. R. McDonald, A. P. Spira, C. F. Pieper, and C. W. Bales. “Quality of Life and Mental Health in Older Adults with Obesity and Frailty: Associations with a Weight Loss Intervention.” J Nutr Health Aging 22, no. 10 (2018): 1259–65. https://doi.org/10.1007/s12603-018-1127-0.Full Text Link to Item
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Porter Starr, Kathryn N., Shelley R. McDonald, Aubrey Jarman, Melissa Orenduff, Richard Sloane, Carl F. Pieper, and Connie W. Bales. “Markers of Renal Function in Older Adults Completing a Higher Protein Obesity Intervention and One Year Later: Findings from the MEASUR-UP Trial.” J Nutr Gerontol Geriatr 37, no. 2 (2018): 117–29. https://doi.org/10.1080/21551197.2018.1478696.Full Text Link to Item
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Bales, Connie W., Kathryn N. Porter Starr, Melissa C. Orenduff, Shelley R. McDonald, Karen Molnar, Aubrey K. Jarman, Ann Onyenwoke, Hillary Mulder, Martha E. Payne, and Carl F. Pieper. “Influence of Protein Intake, Race, and Age on Responses to a Weight-Reduction Intervention in Obese Women.” Curr Dev Nutr 1, no. 5 (May 1, 2017). https://doi.org/10.3945/cdn.117.000703.Full Text Link to Item
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Porter Starr, Kathryn N., Carl F. Pieper, Melissa C. Orenduff, Shelley R. McDonald, Luisa B. McClure, Run Zhou, Martha E. Payne, and Connie W. Bales. “Improved Function With Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail, Obese Older Adults.” J Gerontol a Biol Sci Med Sci 71, no. 10 (October 2016): 1369–75. https://doi.org/10.1093/gerona/glv210.Full Text Open Access Copy Link to Item
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Adam, M. A., S. McDonald, M. Heflin, and S. Lagoo-Deenadayalan. “Incorporating shared decision making into perioperative care of older adults.” Current Surgery Reports 4, no. 8 (August 1, 2016). https://doi.org/10.1007/s40137-016-0148-z.Full Text
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Porter Starr, Kathryn N., Shelley R. McDonald, Julia A. Weidner, and Connie W. Bales. “Challenges in the Management of Geriatric Obesity in High Risk Populations.” Nutrients 8, no. 5 (May 4, 2016). https://doi.org/10.3390/nu8050262.Full Text Open Access Copy Link to Item
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McDonald, Shelley R., and Mitchell T. Heflin. “Update on preoperative assessment for geriatric patients prior to elective surgery.” Geriatr Nurs 37, no. 2 (2016): 160–62. https://doi.org/10.1016/j.gerinurse.2016.02.005.Full Text Link to Item
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Porter Starr, Kathryn N., Shelley R. McDonald, and Connie W. Bales. “Nutritional Vulnerability in Older Adults: A Continuum of Concerns.” Curr Nutr Rep 4, no. 2 (June 2015): 176–84. https://doi.org/10.1007/s13668-015-0118-6.Full Text Link to Item
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McDonald, Shelley R., Kathryn N. Porter Starr, Luisa Mauceri, Melissa Orenduff, Esther Granville, Christine Ocampo, Martha E. Payne, Carl F. Pieper, and Connie W. Bales. “Meal-based enhancement of protein quality and quantity during weight loss in obese older adults with mobility limitations: rationale and design for the MEASUR-UP trial.” Contemp Clin Trials 40 (January 2015): 112–23. https://doi.org/10.1016/j.cct.2014.11.010.Full Text Link to Item
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Porter Starr, Kathryn N., Shelley R. McDonald, and Connie W. Bales. “Obesity and physical frailty in older adults: a scoping review of lifestyle intervention trials.” J Am Med Dir Assoc 15, no. 4 (April 2014): 240–50. https://doi.org/10.1016/j.jamda.2013.11.008.Full Text Link to Item
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McDonald, Shelley R., Rajindar S. Sohal, and Michael J. Forster. “Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice.” Free Radic Biol Med 38, no. 6 (March 15, 2005): 729–36. https://doi.org/10.1016/j.freeradbiomed.2004.11.014.Full Text Link to Item
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McDonald, S. R., and M. J. Forster. “Lifelong vitamin E intake retards age-associated decline of spatial learning ability in apoE-deficient mice.” Age 27, no. 1 (March 1, 2005): 5–16. https://doi.org/10.1007/s11357-005-4003-x.Full Text
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Choi, Joungil, Michael J. Forster, Shelley R. McDonald, Susan T. Weintraub, Christopher A. Carroll, and Robert W. Gracy. “Proteomic identification of specific oxidized proteins in ApoE-knockout mice: relevance to Alzheimer's disease.” Free Radic Biol Med 36, no. 9 (May 1, 2004): 1155–62. https://doi.org/10.1016/j.freeradbiomed.2004.02.002.Full Text Link to Item
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Book Sections
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Little, Milta, Shelley McDonald, David Schlientz, and yooh hie Kim. “Perioperative medical assessment of older adults.” In Pathy’s Principles and Practice of Geriatric Medicine. John Wiley & Sons, 2022.
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Conference Papers
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Zietlow, Kahli E., Serena Wong, Shelley R. McDonald, Cathleen Colón-Emeric, Christy Cassas, Sandhya Lagoo-Deenadayalan, and Mitchell T. Heflin. “Perioperative Optimization of Senior Health (POSH): A Descriptive Analysis of Cancelled Surgery.” In World J Surg, 45:109–15, 2021. https://doi.org/10.1007/s00268-020-05772-z.Full Text Link to Item
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Zietlow, Kahli E., Deborah M. Oyeyemi, Sarah E. Cook, Margaret Hardy, Shelley R. McDonald, Sandhya Lagoo-Deenadayalan, Mitchell T. Heflin, and Heather E. Whitson. “RESEARCHCognition and Capacity to Consent for Elective Surgery.” In J Am Geriatr Soc, 68:2694–96, 2020. https://doi.org/10.1111/jgs.16786.Full Text Link to Item
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