Overview
Design of Clinical Trials
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Current Duke Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2006 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2021 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Scholarly Works
Alirocumab Plus Cemiplimab in Immunorefractory NSCLC: A Single Arm Phase 2 Study.
Journal article Res Sq · June 24, 2026 In preclinical models, PCSK9 mediates cancer immunotherapy resistance and may serve as a novel immuno-inhibitory target. Herein, we report the results from a multi-center, single arm, phase II study evaluating the clinical activity and safety of the PCSK9 ... Full text Link to item CiteAlirocumab plus cemiplimab in immuno-refractory metastatic NSCLC: A single-arm, multi-center, phase 2 study.
Conference Journal of Clinical Oncology · June 1, 2026 2619Background: Immunotherapy resistance remains a significant unmet clinical need for most non-small cell lung cancer (NSCLC) patients. PCSK9 was shown in preclinical models to mediate cancer immunotherapy resistance and may serve as a novel immuno-inhibi ... Full text CiteEarly myopathology of Pompe disease in patients detected by newborn screening
Conference JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY · June 2026 Link to item CiteRecent Grants
Characterization and Diagnosis of Alzheimer's Disease Using mRNA Biomarkers
ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031Treating Central Post-Stroke Pain with Transcranial Low Intensity Focused Ultrasound (PAINLESS)
ResearchStatistical Investigator · Awarded by National Institutes of Health · 2026 - 2028Cascade Amplification Biosensor Technology for Detecting MicroRNA Biomarkers of Alzheimer Disease
ResearchCo Investigator · Awarded by National Institute on Aging · 2025 - 2027View All Grants
Education
University of Wisconsin, Madison ·
1992
Ph.D.