Overview
Design of Clinical Trials
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2006 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2021 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Low intensity focused ultrasound stimulation in stroke: A phase I safety & feasibility trial.
Journal Article Brain Stimul · 2025 OBJECTIVE: We aimed to determine the maximum safe spatial-peak pulse-average intensity (ISPPA) of low-intensity focused ultrasound stimulation (LIFUS) in stroke patients and explore its effect on motor learning and corticospinal excitability. METHODS: We a ... Full text Link to item CiteRandomized Phase II Cancer Clinical Trials to Validate Predictive Biomarkers.
Journal Article Biomedicines · September 26, 2024 OBJECTIVES: The design of cancer clinical trials incorporating biomarkers depends on various factors, including the trial phase, the type of biomarker and whether its role has been validated. This article aims to present a method for designing and analyzin ... Full text Link to item CiteA Dunnett-Type Test and Its Sample Size Calculation for Comparing K ROC Curves with a Control.
Journal Article Diagnostics (Basel, Switzerland) · August 2024 Diagnostic biomarkers are key components of diagnostics. In this paper, we consider diagnostic biomarkers taking continuous values that are associated with a dichotomous disease status, called malignant or benign. The performance of such a biomarker is eva ... Full text CiteRecent Grants
A Phase II, Multi-centre, Randomised, Double-blind, Group Comparator Trial to Assess the Safety and Efficacy of Emactuzumab vs. Placebo in Patients with Tenosynovial Giant Cell Tumour,
Clinical TrialStatistician · Awarded by SynOx Therapeutics Ltd · 2025 - 2030Disparate Survival, Disparate Workforce: An Integrated Approach to Improving Head and Neck Cancer Outcomes and Diversity in the Oncology Workforce
ResearchBiostatistician · Awarded by National Institute of Dental and Craniofacial Research · 2024 - 2029Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform
ResearchCollaborator · Awarded by National Cancer Institute · 2022 - 2027View All Grants
Education, Training & Certifications
University of Wisconsin, Madison ·
1992
Ph.D.