Overview
Design of Clinical Trials
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Survival Analysis
Longitudinal Data Analysis
Clustered Data Analysis
ROC Curve Analysis
Design and Analysis of Microarray Studies
Big Data Analysis
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2006 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2021 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Novel niclosamide stearate prodrug therapeutic shows potential efficacy against naturally occurring canine osteosarcoma in a clinical feasibility study.
Journal Article Am J Vet Res · January 1, 2026 OBJECTIVE: To manufacture and characterize a modified niclosamide stearate (NS) prodrug therapeutic (mNSPT) for use in a small clinical trial in a metastatic canine osteosarcoma (OS) model. ANIMALS: 10 dogs that presented for treatment of nondetectable met ... Full text Link to item CiteDesign and analysis of individually randomized group-treatment trials with time to event outcomes.
Journal Article Lifetime Data Anal · July 2025 In a typical individually randomized group-treatment (IRGT) trial, subjects are randomized between a control arm and an experimental arm. While the subjects randomized to the control arm are treated individually, those in the experimental arm are assigned ... Full text Open Access Link to item CiteLow intensity focused ultrasound stimulation in stroke: A phase I safety & feasibility trial.
Journal Article Brain Stimul · 2025 OBJECTIVE: We aimed to determine the maximum safe spatial-peak pulse-average intensity (ISPPA) of low-intensity focused ultrasound stimulation (LIFUS) in stroke patients and explore its effect on motor learning and corticospinal excitability. METHODS: We a ... Full text Link to item CiteRecent Grants
A Phase II, Multi-centre, Randomised, Double-blind, Group Comparator Trial to Assess the Safety and Efficacy of Emactuzumab vs. Placebo in Patients with Tenosynovial Giant Cell Tumour,
Clinical TrialStatistician · Awarded by SynOx Therapeutics Ltd · 2025 - 2030Cascade Amplification Biosensor Technology for Detecting MicroRNA Biomarkers of Alzheimer Disease
ResearchCo Investigator · Awarded by National Institute on Aging · 2025 - 2027Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform
ResearchCollaborator · Awarded by National Cancer Institute · 2022 - 2027View All Grants
Education
University of Wisconsin, Madison ·
1992
Ph.D.