Shelby Addison Neal | Scholars@Duke

Shelby Addison Neal
Assistant Professor of Obstetrics and Gynecology

Current Research Interests

Predictors of in vitro fertilization success and failure
Preimplantation genetic testing for aneuploidy
Three-dimensional ultrasound imaging

Current Appointments & Affiliations

Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Endocrinology & Fertility, Obstetrics and Gynecology 2021

Contact Information

5601 Arringdon Park Drive, Suite 210, Morrisville, NC 27560
5601 Arringdon Park Drive, Suite 210, Morrisville, NC 27560
shelby.neal@duke.edu (919) 572-4673
Duke Fertility Center

Background
Education, Training, & Certifications
- Board Certified, Reproductive Endocrinology And Infertility Subspecialty Certification, American Board of Obstetrics and Gynecology 2021 - 2023
- Board Certified, Obstetrics And Gynecology, American Board of Obstetrics and Gynecology 2017 - 2023
- Reproductive Endocrinology & Infertility Fellowship, Obstetrics And Gynecology, Thomas Jefferson University, Sidney Kimmel Medical College 2016 - 2019
- Residency, Obstetrics And Gynecology, Medical University of South Carolina 2011 - 2015
- M.D., University of North Carolina, Chapel Hill, School of Medicine 2011
Medical Licensure
- 2019-01251. North Carolina. 2019
Leadership & Clinical Positions at Duke
- Director of Assisted Reproductive Technology, Duke Fertility Center, 2021-present
  Co-Director of Third Party Reproduction, Duke Fertility Center, 2021-present
  Medical Director of Duke Fertility Center, 2023-present
Academic Positions Outside Duke
- Assistant Professor, Department of Obstetrics & Gynecology, Reproductive Medicine, Wake Forest Baptist Health. 2019 - 2021
Recognition
In the News
- JAN 10, 2023 Duke Health News
  
  Becoming an Egg Donor: Answers to Your Questions
- JUL 7, 2022 Duke Health News
  
  Fertility Experts Make Cancer Survivor’s Dream of Family a Reality
Awards & Honors
Expertise
Subject Headings
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Kim, Julia, George Patounakis, Caroline Juneau, Scott Morin, Shelby Neal, Paul Bergh, Emre Seli, and Richard Scott. “The Appraisal of Body Content (ABC) trial: Increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes.” Fertil Steril 116, no. 2 (August 2021): 444–52. https://doi.org/10.1016/j.fertnstert.2020.12.037.
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  - Kim, Julia, Caroline Juneau, George Patounakis, Scott Morin, Shelby Neal, Emre Seli, and Richard Scott. “The appraisal of body content (ABC) trial: obesity does not significantly impact gamete production in infertile men and women.” J Assist Reprod Genet 37, no. 11 (November 2020): 2733–42. https://doi.org/10.1007/s10815-020-01930-3.
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  - Klimczak, Amber M., Andres Reig, Shelby A. Neal, Emre Seli, and Richard T. Scott. “Interpretation of noninvasive prenatal testing results following in vitro fertilization and preimplantation genetic testing for aneuploidy.” Am J Obstet Gynecol Mfm 2, no. 4 (November 2020): 100232. https://doi.org/10.1016/j.ajogmf.2020.100232.
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  - Neal, S., S. Morin, M. Werner, N. -. A. Gueye, P. Pirtea, G. Patounakis, R. Scott, and L. Goodman. “Three-dimensional ultrasound diagnosis of adenomyosis is not associated with adverse pregnancy outcome following single thawed euploid blastocyst transfer: prospective cohort study.” Ultrasound Obstet Gynecol 56, no. 4 (October 2020): 611–17. https://doi.org/10.1002/uog.22065.
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  - Murugappan, G., J. G. Kim, J. D. Kort, B. M. Hanson, S. A. Neal, A. W. Tiegs, E. K. Osman, R. T. Scott, and R. B. Lathi. “Prognostic value of blastocyst grade after frozen euploid embryo transfer in patients with recurrent pregnancy loss.” F and S Reports 1, no. 2 (September 1, 2020): 113–18. https://doi.org/10.1016/j.xfre.2020.07.001.
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  - Osman, E. K., S. A. Neal, A. W. Tiegs, B. M. Hanson, J. G. Kim, J. M. Franasiak, and R. T. Scott. “Consistency in rates of diagnosis of embryonic mosaicism, segmental abnormalities, and “no call” results among experienced embryologists performing preimplantation genetic testing for aneuploidy.” F and S Reports 1, no. 2 (September 1, 2020): 119–24. https://doi.org/10.1016/j.xfre.2020.05.005.
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  - Morin, Scott J., Brent M. Hanson, Caroline R. Juneau, Shelby A. Neal, Jessica N. Landis, Richard T. Scott, and James M. Hotaling. “A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia.” Asian J Androl 22, no. 2 (2020): 222–26. https://doi.org/10.4103/aja.aja_58_19.
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  - Neal, Shelby A., Scott J. Morin, Marie D. Werner, Ndeye-Aicha Gueye, Paul Pirtea, Richard T. Scott, and Linnea R. Goodman. “Three-dimensional ultrasound diagnosis of T-shaped uterus is associated with adverse pregnancy outcomes after embryo transfer.” Reprod Biomed Online 39, no. 5 (November 2019): 777–83. https://doi.org/10.1016/j.rbmo.2019.07.030.
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  - Neal, Shelby A., L. Sun, C. Jalas, S. J. Morin, T. A. Molinaro, and R. T. Scott. “When next-generation sequencing-based preimplantation genetic testing for aneuploidy (PGT-A) yields an inconclusive report: diagnostic results and clinical outcomes after re biopsy.” J Assist Reprod Genet 36, no. 10 (October 2019): 2103–9. https://doi.org/10.1007/s10815-019-01550-6.
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  - Neal, Shelby A., Scott J. Morin, Jason M. Franasiak, Linnea R. Goodman, Caroline R. Juneau, Eric J. Forman, Marie D. Werner, and Richard T. Scott. “Preimplantation genetic testing for aneuploidy is cost-effective, shortens treatment time, and reduces the risk of failed embryo transfer and clinical miscarriage.” Fertil Steril 110, no. 5 (October 2018): 896–904. https://doi.org/10.1016/j.fertnstert.2018.06.021.
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  - Neal, Shelby A., and Marie D. Werner. “Quest for a less invasive approach to preimplantation genetic testing remains ongoing.” Fertil Steril 110, no. 5 (October 2018): 845–46. https://doi.org/10.1016/j.fertnstert.2018.06.038.
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  - Juneau, Caroline R., Jason M. Franasiak, Linnea R. Goodman, Diego Marin, Katherine Scott, Scott J. Morin, Shelby A. Neal, Jeffrey E. Juneau, and Richard T. Scott. “Celiac disease is not more prevalent in patients undergoing in vitro fertilization and does not affect reproductive outcomes with or without treatment: a large prospective cohort study.” Fertil Steril 110, no. 3 (August 2018): 437–42. https://doi.org/10.1016/j.fertnstert.2018.03.030.
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  - Morin, S. J., G. Patounakis, C. R. Juneau, S. A. Neal, R. T. Scott, and E. Seli. “Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance.” Hum Reprod 33, no. 8 (August 1, 2018): 1489–98. https://doi.org/10.1093/humrep/dey238.
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  - Neal, Shelby A., and Marie D. Werner. “The impact of contemporary preimplantation genetic screening and diagnosis on the detection of aneuploidy and inherited genetic diseases.” Birth Defects Res 110, no. 8 (May 1, 2018): 644–47. https://doi.org/10.1002/bdr2.1220.
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  - Rashid, Tariq, Jennifer L. Young-Pierce, Elizabeth Garrett-Mayer, Whitney Graybill, Shelby Neal, and Laura S. Spruill. “CD8, FoxP3, and CD45RO+ Lymphocytic Infiltrates in Type I and Type II Endometrial Cancers in African American and European American Females.” Int J Gynecol Pathol 36, no. 6 (November 2017): 540–49. https://doi.org/10.1097/PGP.0000000000000359.
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  - Neal, Shelby A., Jason M. Franasiak, Eric J. Forman, Marie D. Werner, Scott J. Morin, Xin Tao, Nathan R. Treff, and Richard T. Scott. “High relative deoxyribonucleic acid content of trophectoderm biopsy adversely affects pregnancy outcomes.” Fertil Steril 107, no. 3 (March 2017): 731-736.e1. https://doi.org/10.1016/j.fertnstert.2016.11.013.
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  - Franasiak, Jason, Daniel Kaser, Linnea Goodman, George Patounakis, Caroline Juneau, Scott Morin, Shelby Neal, William Schlaff, and Richard Scott. “Characterization of reproductive endocrinology and infertility (REI) fellowship applicants: guiding our mentees toward success.” Fertil Res Pract 3 (2017): 18. https://doi.org/10.1186/s40738-017-0045-x.
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  - Neal, Shelby A., Whitney S. Graybill, Elizabeth Garrett-Mayer, Misty L. McDowell, Virginia E. McLean, Catherine H. Watson, Jennifer Y. Pierce, Matthew F. Kohler, and William T. Creasman. “Lymphovascular space invasion in uterine corpus cancer: What is its prognostic significance in the absence of lymph node metastases?” Gynecol Oncol 142, no. 2 (August 2016): 278–82. https://doi.org/10.1016/j.ygyno.2016.05.037.
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  - Treff, Nathan R., Katherine Thompson, Michael Rafizadeh, Michael Chow, Liza Morrison, Xin Tao, Heather Garnsey, et al. “SNP array-based analyses of unbalanced embryos as a reference to distinguish between balanced translocation carrier and normal blastocysts.” J Assist Reprod Genet 33, no. 8 (August 2016): 1115–19. https://doi.org/10.1007/s10815-016-0734-0.
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  - Addison, Shelby, R Edward Coleman, Sheng Feng, Gary McDaniel, and Virginia Byers Kraus. “Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation.” Arthritis Rheum 60, no. 11 (November 2009): 3366–73. https://doi.org/10.1002/art.24856.
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  - Henrotin, Yves, Shelby Addison, Virginia Kraus, and Michelle Deberg. “Type II collagen markers in osteoarthritis: what do they indicate?” Curr Opin Rheumatol 19, no. 5 (September 2007): 444–50. https://doi.org/10.1097/BOR.0b013e32829fb3b5.
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- Book Sections
  - Neal, S. A., J. M. Franasiak, and R. T. Scott. “Hematologic disease in implantation failure.” In Recurrent Implantation Failure: Etiologies and Clinical Management, 125–34, 2018. https://doi.org/10.1007/978-3-319-71967-2_8.
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Teaching & Mentoring
Teaching Activities
- Duke University School of Medicine Lectures
  • Evaluation and Management of Infertility, May 2023
  
  Duke Reproductive Endocrinology and Infertility Fellows’ Conference
  • Recurrent Pregnancy Loss, April 2021
  • Immunoassays, June 2021
  • Evaluation of the Infertile Female, July 2021 & August 2022
  • Introduction to Assisted Reproductive Technology, July 2021
  • Ovulation Induction, August 2021 & September 2022
  • Endocrinology of Pregnancy, November 2021 & October 2022
  • Amenorrhea, January 2022 & January 2023
  • Gamete and Embryo Donation, February 2022
  • Gestational Carrier Screening, March 2022
  • Complications of Oocyte Retrieval, April 2022
  • Gametogenesis and Fertilization, July 2022
  • Neuroendocrinology, February 2023
  
  Duke Maternal Fetal Medicine Fellows’ Conference
  • Congenital Adrenal Hyperplasia, August 2021
  
  Wake Forest Obstetrics & Gynecology Resident Conference
  • Amenorrhea, March 2020
  • Mullerian Anomalies, March 2020
  • Recurrent Pregnancy Loss, January 2021
  
  Wake Forest Gynecologic Oncology Fellows’ Conference
  • Fertility Preservation for Cancer Patients, November 2019
  
  Wake Forest Obstetrics & Gynecology Medical Student Clerkship Lectures
  • Abnormal Uterine Bleeding, July 2020, August 2020, October 2020, January 2021
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
Service to the Profession
Service to Duke
- Duke Alumni Admissions Advisory Committee. 2006 2006

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Education, Training, & Certifications

Medical Licensure

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

In the News

Awards & Honors

Subject Headings

Selected Publications

Academic Articles

Book Sections

Teaching Activities

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Service to Duke