Soman Ninan Abraham
Grace Kerby Distinguished Professor of Pathology
The Abraham laboratory is interested in developing innovative approaches for curbing microbial infections through the study of the molecular interactions occurring between pathogenic bacteria and prominent immune and epithelial cells. We believe that there is a significant amount of crosstalk occurring between bacteria and host cells during infection and that the outcome of this interaction dictates both how quickly the infection is cleared and the severity of the pathology associated with the infection. We also believe that through deciphering this crosstalk we should be able to selectively promote certain beneficial interactions while abrogating the harmful ones.
There are two major research areas being pursued in this laboratory. The first involves elucidating the role of mast cells in modulating immune responses to microbes. Our studies have revealed that mast cells play a key sentinel role and upon bacterial or viral infection, modulate both innate and adaptive immune responses through the release of immunomodulatory molecules borne in granules. Our current investigations are centered on elucidating the molecular and cellular aspects of how mast cells mediate their immunomodulatory role. We are also examining several mast cell-targeted strategies to boost immunity to infections as well as reduce any pathological consequences of infection.
The second area of research investigates cross-talk between distinct infectious agents such as Uropathogenic E. coli, Salmonella typhimurium and Yersinia pestis and the immune system. We have recognized that different pathogens possess distinct mechanisms to evade or coopt one or more immune cells to establish infection. We have also unraveled novel intracellular innate host defense activities including expulsion of whole bacteria from infected epithelial cells, a feat mediated by immune recognition molecules and the cellular trafficking system.
Cumulatively, our studies should facilitate the design of innovative strategies to combat pathogens that selectively potentiate the host’s immune response without evoking some of its harmful side effects.
Current Appointments & Affiliations
- Grace Kerby Distinguished Professor of Pathology, Pathology, Clinical Science Departments 2018
- Professor in Pathology, Pathology, Clinical Science Departments 2003
- Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2015
- Professor in Immunology, Immunology, Basic Science Departments 2015
- Associate Professor of Cell Biology, Cell Biology, Basic Science Departments 2022
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1997
Contact Information
- 255 Jones Bldg, Durham, NC 27710
- Duke Box 3020, Durham, NC 27710
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soman.abraham@duke.edu
(919) 972-1264
- Background
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Education, Training, & Certifications
- Postdoctoral Fellowship, University of Tennessee, Knoxville 1982 - 1986
- Ph.D., Newcastle University (United Kingdom) 1981
- M.S., Ahmadu Bello University (Nigeria) 1978
- B.S., Ahmadu Bello University (Nigeria) 1976
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Previous Appointments & Affiliations
- Associate Professor of Immunology, Immunology, Basic Science Departments 2002 - 2015
- Associate Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2002 - 2015
- Associate Professor in Pathology with tenure, Pathology, Clinical Science Departments 2000 - 2003
- Associate Professor of Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 1997 - 2002
- Associate Professor in Pathology, Pathology, Clinical Science Departments 1997 - 2000
- Instructor, Temporary of Pathology, Pathology, Clinical Science Departments 1997
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Academic Positions Outside Duke
- Clinical Director, Washington University in St. Louis. 1993 - 1997
- Associate Clinical Director, Washington University in St. Louis. 1990 - 1993
- Assistant Professor, Washington University in St. Louis. 1990 - 1997
- Assistant Professor, University of Tennessee, Knoxville. 1986 - 1990
- Recognition
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In the News
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MAR 2, 2021 Duke Health News -
MAY 19, 2020 Duke Health News -
NOV 25, 2019 Innovation and Entrepreneurship -
NOV 9, 2018 Duke Health News -
FEB 21, 2018 Duke Health News -
JUL 21, 2016 Duke Today -
JUL 21, 2016 -
OCT 7, 2015 Duke Translational Medicine Institute -
SEP 1, 2015 Australian Broadcasting’s “The Health Report" -
SEP 1, 2015 Australian Broadcasting’s “The Health Report -
JUN 3, 2015 Duke Today -
JUN 3, 2015 -
SEP 25, 2014 -
SEP 19, 2014 -
DEC 15, 2013
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Awards & Honors
- Expertise
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Global Scholarship
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Research
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- Research
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Selected Grants
- Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
- Integrated Training in Anesthesiology Research awarded by National Institutes of Health 1996 - 2026
- Platelet-mast cell interactions in pathogen induced vascular pathology awarded by National Institutes of Health 2021 - 2025
- Basic Immunology Training Program awarded by National Institutes of Health 2020 - 2025
- A novel vaccination strategy to curb recUTIs awarded by National Institutes of Health 2023 - 2024
- The role of TRPV4 in migraine pain with focus on non-neural, keratinocytes and mast cells and mechanisms of racial differences in migraine pain suffering awarded by National Institutes of Health 2021 - 2024
- Development of Humanized Mouse Models for Studies of the Urogenital Microbiome awarded by University of Wisconsin, Madison 2023 - 2024
- Loss of Bladder Control Following Recurrent Infections awarded by National Institutes of Health 2020 - 2024
- Adjuvant Comparison for Peanut Allergy Immunotherapy awarded by National Institutes of Health 2022 - 2023
- Duke KURe Program awarded by National Institutes of Health 2013 - 2023
- Mast cell activation as a determinant of neurologic injury after cardiac arrest awarded by National Institutes of Health 2020 - 2023
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
- Aberrant remodeling of bladder following infection awarded by National Institutes of Health 2019 - 2023
- Vaccine Adjuvant Discovery Program awarded by University of Montana 2019 - 2022
- Urinary Lactobacilli and microbial interference in the aging urinary microbiome 2020 - 2022
- Transmission electron microscope (TEM) awarded by National Institutes of Health 2019 - 2021
- Developing a SARS-CoV-2 subunit vaccine for nasal immunization 2020 - 2021
- Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2021
- Immunotherapy to combat skin infections awarded by National Institutes of Health 2019 - 2021
- Combatting Bladder Cancer by Inducing Epithelial Turnover awarded by National Institutes of Health 2019 - 2021
- Adjuvant Discovery Program (Option #3) awarded by National Institutes of Health 2014 - 2020
- Novel Adjuvants and Carriers for Opiod Vaccines awarded by National Institutes of Health 2014 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Adjuvant Discovery Program (Option #2) awarded by National Institutes of Health 2014 - 2019
- IL-27 in skin host defense and regeneration awarded by National Institutes of Health 2017 - 2019
- Platelets as regulators of inflammation and tissue injury after cardiac surgery awarded by American Heart Association 2015 - 2019
- Immune mediated exocytosis of intravesicular UPEC from bladder cells awarded by National Institutes of Health 2014 - 2018
- Understanding the Mechanism of Mucosal Immunotherapy awarded by University of North Carolina - Chapel Hill 2012 - 2018
- Overcoming Immunosenescence by Nanoparticle-Mediated Activation awarded by Columbia University 2017 - 2018
- Adjuvant Discovery Program (Option #1) awarded by National Institutes of Health 2014 - 2017
- Platelet/Mast cell Interactions as Determinants of End-Organ Injury in Cardiac Surgery awarded by National Institutes of Health 2015 - 2017
- Enhancing dendritic cell migration to drive potent anti-tumor immune responses awarded by National Institutes of Health 2013 - 2017
- Mucosal vaccination to protect against HIV-1 infection at mucosal sites awarded by National Institutes of Health 2012 - 2017
- Mast Cells in Dengue Pathology and Prevention awarded by National Institutes of Health 2013 - 2017
- Adjuvant Discovery Program awarded by National Institutes of Health 2014 - 2017
- Institutional Training Grant in Pediatric Infectious Disease awarded by National Institutes of Health 2011 - 2016
- The role of SP-A in Mp-induced exacerbations during allergic airway disease awarded by National Institutes of Health 2014 - 2015
- Mechanism of Bacterial Expulsion from Infected Bladder Cells. awarded by National Institutes of Health 2012 - 2014
- Overcoming Immunosenescence by Nanoparticle-Mediated Activation awarded by National Institutes of Health 2012 - 2014
- The role of SP-A in Mp-induced exacerbations during allergic airway disease. awarded by National Institutes of Health 2012 - 2014
- Development of Efficacious and Stable Nasal Vaccine Formulations awarded by National Institutes of Health 2009 - 2014
- Targeting EGFRvIII in Brain Tumors with Bispecific Antibodies awarded by National Institutes of Health 2013 - 2014
- Nasal adjuvant to enhance anti-cocaine vaccines awarded by National Institutes of Health 2011 - 2013
- Enterotoxin targeting and delivery mechanisms awarded by National Institutes of Health 2006 - 2012
- Modulation of Bladder cAMP to combat UTI's awarded by National Institutes of Health 2007 - 2012
- Caveolae Mediated Bacterial Uptake in the Urinary Tract awarded by National Institutes of Health 2001 - 2011
- Role Of Surfactant In Innate and Adaptive Immunity awarded by National Institutes of Health 2001 - 2011
- Development of Efficacious Vaccine Against UTI's awarded by National Institutes of Health 2008 - 2011
- Small cationic antimicrobial peptides: activators of innate & adaptive immunity awarded by National Institutes of Health 2008 - 2010
- Ligand Receptor Interactions in UTIs awarded by National Institutes of Health 1976 - 2010
- Mast Cells and IBD Pathogenesis awarded by National Institutes of Health 2006 - 2009
- Pseudomonas Invasion and the Role of Caveolin-2 awarded by National Institutes of Health 2006 - 2009
- Duke PREP: Minority Recruitment into Biomedical Sciences awarded by National Institutes of Health 2003 - 2008
- Mast Cell Activator as Adjuvant for Biodefense Vaccines awarded by National Institutes of Health 2005 - 2007
- Proteome Mining in Caveolae of the Bladder Epithelium awarded by National Institutes of Health 2004 - 2007
- Detection of in vivo ETEC vesicle production awarded by National Institutes of Health 2003 - 2006
- Mast Cells in Pulmonary Inflammation awarded by National Institutes of Health 1998 - 2001
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External Relationships
- Duke -National Univeristy of Singapore
- Mastezellen Bio Inc.
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Iskarpatyoti, Jason A., Jianling Shi, Mathew A. Abraham, Abhay P. S. Rathore, Yuxuan Miao, and Soman N. Abraham. “Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter.” Cell Rep 40, no. 13 (September 27, 2022): 111346. https://doi.org/10.1016/j.celrep.2022.111346.Full Text Link to Item
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Song, Chang Hyun, Young Ho Kim, Manisha Naskar, Byron W. Hayes, Mathew A. Abraham, Joo Hwan Noh, Gyeongseo Suk, et al. “Lactobacillus crispatus Limits Bladder Uropathogenic E. coli Infection by Triggering a Host Type I Interferon Response.” Proc Natl Acad Sci U S A 119, no. 33 (August 16, 2022): e2117904119. https://doi.org/10.1073/pnas.2117904119.Full Text Link to Item
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Chacón-Salinas, Rommel, Anna Di Nardo, and Soman N. Abraham. “Editorial: Mast Cells: Bridging Host-Microorganism Interactions.” Front Immunol 13 (2022): 827375. https://doi.org/10.3389/fimmu.2022.827375.Full Text Link to Item
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Cao, Can, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Wenlei Ye, Byron W. Hayes, et al. “Structure, function and pharmacology of human itch GPCRs.” Nature 600, no. 7887 (December 2021): 170–75. https://doi.org/10.1038/s41586-021-04126-6.Full Text Link to Item
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Wu, Jianxuan, Chunjing Bao, R Lee Reinhardt, and Soman N. Abraham. “Local induction of bladder Th1 responses to combat urinary tract infections.” Proc Natl Acad Sci U S A 118, no. 10 (March 9, 2021). https://doi.org/10.1073/pnas.2026461118.Full Text Link to Item
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Wu, Jianxuan, and Soman N. Abraham. “The Roles of T cells in Bladder Pathologies.” Trends Immunol 42, no. 3 (March 2021): 248–60. https://doi.org/10.1016/j.it.2021.01.003.Full Text Link to Item
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Johnson-Weaver, Brandi T., Hae Woong Choi, Hang Yang, Josh A. Granek, Cliburn Chan, Soman N. Abraham, and Herman F. Staats. “Nasal Immunization With Small Molecule Mast Cell Activators Enhance Immunity to Co-Administered Subunit Immunogens.” Front Immunol 12 (2021): 730346. https://doi.org/10.3389/fimmu.2021.730346.Full Text Link to Item
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Syenina, Ayesa, Wilfried A. A. Saron, Cyril J. Jagaraj, Siham Bibi, Michel Arock, Duane J. Gubler, Abhay P. S. Rathore, Soman N. Abraham, and Ashley L. St John. “Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability.” Viruses 12, no. 12 (December 2, 2020). https://doi.org/10.3390/v12121379.Full Text Link to Item
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Wang, Jun, Jianxuan Wu, Dimitrios Moris, Byron Hayes, Soman N. Abraham, and Linda C. Cendales. “Introducing a novel experimental model of bladder transplantation in mice.” Am J Transplant 20, no. 12 (December 2020): 3558–66. https://doi.org/10.1111/ajt.15912.Full Text Link to Item
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Wu, Jianxuan, Byron W. Hayes, Cassandra Phoenix, Gustavo Sosa Macias, Yuxuan Miao, Hae Woong Choi, Francis M. Hughes, J. Todd Purves, R. Lee Reinhardt, and Soman N. Abraham. “A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections.” Nat Immunol 21, no. 6 (June 2020): 671–83. https://doi.org/10.1038/s41590-020-0688-3.Full Text Link to Item
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Mencarelli, Andrea, Merry Gunawan, Kylie Su Mei Yong, Pradeep Bist, Wilson Wei Sheng Tan, Sue Yee Tan, Min Liu, et al. “A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.” J Leukoc Biol 107, no. 5 (May 2020): 797–807. https://doi.org/10.1002/JLB.3MA1219-210RR.Full Text Link to Item
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Karhausen, Jörn, Hae Woong Choi, Krishna Rao Maddipati, Joseph P. Mathew, Qing Ma, Yacine Boulaftali, Robert Hugh Lee, Wolfgang Bergmeier, and Soman N. Abraham. “Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury.” Sci Adv 6, no. 12 (March 2020): eaay6314. https://doi.org/10.1126/sciadv.aay6314.Full Text Link to Item
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St John, Ashley L., Hae Woong Choi, Q David Walker, Bruce Blough, Cynthia M. Kuhn, Soman N. Abraham, and Herman F. Staats. “Novel mucosal adjuvant, mastoparan-7, improves cocaine vaccine efficacy.” Npj Vaccines 5, no. 1 (2020): 12. https://doi.org/10.1038/s41541-020-0161-1.Full Text Open Access Copy Link to Item
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Jones, Dorothy I., Justin J. Pollara, Brandi T. Johnson-Weaver, Celia C. LaBranche, David C. Montefiori, David J. Pickup, Sallie R. Permar, et al. “Optimized Mucosal Modified Vaccinia Virus Ankara Prime/Soluble gp120 Boost HIV Vaccination Regimen Induces Antibody Responses Similar to Those of an Intramuscular Regimen.” J Virol 93, no. 14 (July 15, 2019). https://doi.org/10.1128/JVI.00475-19.Full Text Link to Item
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Choi, Hae Woong, Cliburn Chan, Ivo D. Shterev, Heather E. Lynch, Taylor J. Robinette, Brandi T. Johnson-Weaver, Jianling Shi, et al. “Identification of Novel Mast Cell Activators Using Cell-Based High-Throughput Screening.” Slas Discov 24, no. 6 (July 2019): 628–40. https://doi.org/10.1177/2472555219834699.Full Text Link to Item
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Arifuzzaman, Mohammad, Yuvon R. Mobley, Hae Woong Choi, Pradeep Bist, Cristina A. Salinas, Zachary D. Brown, Swaine L. Chen, Herman F. Staats, and Soman N. Abraham. “MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.” Sci Adv 5, no. 1 (January 2019): eaav0216. https://doi.org/10.1126/sciadv.aav0216.Full Text Open Access Copy Link to Item
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Bracken, Sonali J., Soman Abraham, and Amanda S. MacLeod. “Autoimmune Theories of Chronic Spontaneous Urticaria.” Front Immunol 10 (2019): 627. https://doi.org/10.3389/fimmu.2019.00627.Full Text Link to Item
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Choi, Hae Woong, Jutamas Suwanpradid, Il Hwan Kim, Herman F. Staats, Muzlifah Haniffa, Amanda S. MacLeod, and Soman N. Abraham. “Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles.” Science 362, no. 6415 (November 9, 2018). https://doi.org/10.1126/science.aao0666.Full Text Link to Item
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Jin, Cong, Christopher P. Shelburne, Guojie Li, Erin N. Potts, Kristina J. Riebe, Gregory D. Sempowski, W Michael Foster, and Soman N. Abraham. “Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.” J Clin Invest 128, no. 10 (October 1, 2018): 4742–43. https://doi.org/10.1172/JCI123039.Full Text Link to Item
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Arifuzzaman, Mohammad, WX Gladys Ang, Hae Woong Choi, Matthew L. Nilles, Ashley L. St John, and Soman N. Abraham. “Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.” Jci Insight 3, no. 18 (September 20, 2018). https://doi.org/10.1172/jci.insight.122188.Full Text Link to Item
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Johnson-Weaver, Brandi, Hae Woong Choi, Soman N. Abraham, and Herman F. Staats. “Mast cell activators as novel immune regulators.” Curr Opin Pharmacol 41 (August 2018): 89–95. https://doi.org/10.1016/j.coph.2018.05.004.Full Text Link to Item
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Saron, Wilfried A. A., Abhay P. S. Rathore, Lim Ting, Eng Eong Ooi, Jenny Low, Soman N. Abraham, and Ashley L. St John. “Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.” Sci Adv 4, no. 7 (July 2018): eaar4297. https://doi.org/10.1126/sciadv.aar4297.Full Text Link to Item
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St John, Ashley L., WX Gladys Ang, Abhay P. S. Rathore, and Soman N. Abraham. “Reprograming immunity to food allergens.” J Allergy Clin Immunol 141, no. 5 (May 2018): 1936-1939.e2. https://doi.org/10.1016/j.jaci.2018.01.020.Full Text Link to Item
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Choi, Hae Woong, and Soman N. Abraham. “In Vitro and In Vivo IgE-/Antigen-Mediated Mast Cell Activation.” Methods Mol Biol 1799 (2018): 71–80. https://doi.org/10.1007/978-1-4939-7896-0_7.Full Text Link to Item
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Jin, Cong, Christopher P. Shelburne, Guojie Li, Erin N. Potts, Kristina J. Riebe, Gregory D. Sempowski, W Michael Foster, and Soman N. Abraham. “Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.” J Clin Invest 127, no. 10 (October 2, 2017): 3913. https://doi.org/10.1172/JCI97321.Full Text Link to Item
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Miao, Yuxuan, Pradeep Bist, Jianxuan Wu, Qing Zhao, Qi-Jing Li, Ying Wan, and Soman N. Abraham. “Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.” Cell Host Microbe 22, no. 3 (September 13, 2017): 330-342.e4. https://doi.org/10.1016/j.chom.2017.08.002.Full Text Link to Item
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Ali, Ased S. M., Catherine Mowbray, Marcelo Lanz, Anna Stanton, Samantha Bowen, Claire L. Varley, Paul Hilton, et al. “Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection.” Scientific Reports 7, no. 1 (September 2017): 11039. https://doi.org/10.1038/s41598-017-10445-4.Full Text
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Wu, Jianxuan, Yuxuan Miao, and Soman N. Abraham. “The multiple antibacterial activities of the bladder epithelium.” Ann Transl Med 5, no. 2 (January 2017): 35. https://doi.org/10.21037/atm.2016.12.71.Full Text Link to Item
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Yang, Bin, Jutamas Suwanpradid, Roberto Sanchez-Lagunes, Hae Woong Choi, Peter Hoang, Donghai Wang, Soman N. Abraham, and Amanda S. MacLeod. “IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense.” Journal of Investigative Dermatology 137, no. 5 (2017): 1166–75. https://doi.org/10.1016/j.jid.2017.01.010.Full Text Link to Item
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Choi, Hae Woong, Samantha E. Bowen, Yuxuan Miao, Cheryl Y. Chan, Edward A. Miao, Magnus Abrink, Adam J. Moeser, and Soman N. Abraham. “Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.” Immunity 45, no. 6 (December 20, 2016): 1258–69. https://doi.org/10.1016/j.immuni.2016.11.003.Full Text Link to Item
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Hayes, Byron W., and Soman N. Abraham. “Innate Immune Responses to Bladder Infection.” Microbiol Spectr 4, no. 6 (December 2016). https://doi.org/10.1128/microbiolspec.UTI-0024-2016.Full Text Link to Item
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Ang, WX Gladys, Alison M. Church, Mike Kulis, Hae Woong Choi, A Wesley Burks, and Soman N. Abraham. “Mast cell desensitization inhibits calcium flux and aberrantly remodels actin.” J Clin Invest 126, no. 11 (November 1, 2016): 4103–18. https://doi.org/10.1172/JCI87492.Full Text Link to Item
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Karhausen, Jörn, and Soman N. Abraham. “How mast cells make decisions.” J Clin Invest 126, no. 10 (October 3, 2016): 3735–38. https://doi.org/10.1172/JCI90361.Full Text Link to Item
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Miao, Yuxuan, Jianxuan Wu, and Soman N. Abraham. “Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex.” Immunity 45, no. 1 (July 19, 2016): 94–105. https://doi.org/10.1016/j.immuni.2016.06.023.Full Text Link to Item
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O’Brien, T. F., K. Bao, M. Dell’Aringa, W. X. G. Ang, S. Abraham, and R. L. Reinhardt. “Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation.” Mucosal Immunol 9, no. 3 (May 2016): 597–609. https://doi.org/10.1038/mi.2015.78.Full Text Link to Item
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Choi, Hae Woong, and Soman N. Abraham. “Why Serological Responses during Cystitis are Limited.” Pathogens 5, no. 1 (February 14, 2016). https://doi.org/10.3390/pathogens5010019.Full Text Open Access Copy Link to Item
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Abraham, S. N., and W. J. Miao Y. “Ubiquitination of TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex (Accepted).” Immunity, 2016.
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Hsia, Bethany J., Julie G. Ledford, Erin N. Potts-Kant, Vinayak S. Nikam, Njira L. Lugogo, W Michael Foster, Monica Kraft, Soman N. Abraham, and Jo Rae Wright. “Correction notice for TNF-R on mast cells regulate airway responses to Mycoplasma pneumoniae.” J Allergy Clin Immunol 137, no. 1 (January 2016): 336. https://doi.org/10.1016/j.jaci.2015.09.049.Full Text Link to Item
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Abraham, Soman N., and Yuxuan Miao. “The nature of immune responses to urinary tract infections.” Nat Rev Immunol 15, no. 10 (October 2015): 655–63. https://doi.org/10.1038/nri3887.Full Text Link to Item
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Miao, Yuxuan, Guojie Li, Xiaoli Zhang, Haoxing Xu, and Soman N. Abraham. “A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion.” Cell 161, no. 6 (June 4, 2015): 1306–19. https://doi.org/10.1016/j.cell.2015.05.009.Full Text Link to Item
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Choi, Hae Woong, and Soman N. Abraham. “Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms.” Mol Immunol 63, no. 1 (January 2015): 74–79. https://doi.org/10.1016/j.molimm.2014.02.006.Full Text Link to Item
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Mehershahi, K. S., S. N. Abraham, and S. L. Chen. “Complete genome sequence of uropathogenic Escherichia coli strain CI5.” Genome Announcements 3, no. 3 (January 1, 2015). https://doi.org/10.1128/genomeA.00558-15.Full Text
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St John, Ashley L., WX Gladys Ang, Min-Nung Huang, Christian A. Kunder, Elizabeth W. Chan, Michael D. Gunn, and Soman N. Abraham. “S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection.” Immunity 41, no. 3 (September 18, 2014): 440–50. https://doi.org/10.1016/j.immuni.2014.07.013.Full Text Link to Item
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Chang, Jui-Chih, Jason Leung, Tao Tang, Zoie E. Holzknecht, Matthew G. Hartwig, R. Duane Davis, William Parker, Soman N. Abraham, and Shu S. Lin. “Cromolyn ameliorates acute and chronic injury in a rat lung transplant model.” J Heart Lung Transplant 33, no. 7 (July 2014): 749–57. https://doi.org/10.1016/j.healun.2014.03.004.Full Text Link to Item
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Miao, Yuxuan, and Soman N. Abraham. “Kidney α-intercalated cells and lipocalin 2: defending the urinary tract.” J Clin Invest 124, no. 7 (July 2014): 2844–46. https://doi.org/10.1172/JCI76630.Full Text Link to Item
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Miao, Yuxuan, and Soman N. Abraham. “Peeing pentraxins.” Immunity 40, no. 4 (April 17, 2014): 460–62. https://doi.org/10.1016/j.immuni.2014.03.006.Full Text Link to Item
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Choi, Hae Woong, Rhea Brooking-Dixon, Subham Neupane, Chul-Jin Lee, Edward A. Miao, Herman F. Staats, and Soman N. Abraham. “Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP.” Immunity 39, no. 6 (December 12, 2013): 1108–20. https://doi.org/10.1016/j.immuni.2013.11.009.Full Text Link to Item
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Sample, Christopher J., Kathryn E. Hudak, Brice E. Barefoot, Matthew D. Koci, Moses S. Wanyonyi, Soman Abraham, Herman F. Staats, and Elizabeth A. Ramsburg. “A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses.” Peptides 48 (October 2013): 96–105. https://doi.org/10.1016/j.peptides.2013.07.014.Full Text Link to Item
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Karhausen, Jörn, Ma Qing, Amelia Gibson, Adam J. Moeser, Harald Griefingholt, Laura P. Hale, Soman N. Abraham, and G Burkhard Mackensen. “Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.” Crit Care Med 41, no. 9 (September 2013): e200–210. https://doi.org/10.1097/CCM.0b013e31827cac7a.Full Text Link to Item
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Bowen, Samantha E., Christine L. Watt, Inga J. Murawski, Indra R. Gupta, and Soman N. Abraham. “Interplay between vesicoureteric reflux and kidney infection in the development of reflux nephropathy in mice.” Dis Model Mech 6, no. 4 (July 2013): 934–41. https://doi.org/10.1242/dmm.011650.Full Text Link to Item
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St John, Ashley L., Soman N. Abraham, and Duane J. Gubler. “Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis.” Nat Rev Microbiol 11, no. 6 (June 2013): 420–26. https://doi.org/10.1038/nrmicro3030.Full Text Link to Item
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St John, Ashley L., and Soman N. Abraham. “Innate immunity and its regulation by mast cells.” J Immunol 190, no. 9 (May 1, 2013): 4458–63. https://doi.org/10.4049/jimmunol.1203420.Full Text Link to Item
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St John, Ashley L., Abhay P. S. Rathore, Bhuvanakantham Raghavan, Mah-Lee Ng, and Soman N. Abraham. “Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.” Elife 2 (April 30, 2013): e00481. https://doi.org/10.7554/eLife.00481.Full Text Open Access Copy Link to Item
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Gwinn, William M., Brandi T. Johnson, Shaun M. Kirwan, Ashley E. Sobel, Soman N. Abraham, Michael D. Gunn, and Herman F. Staats. “A comparison of non-toxin vaccine adjuvants for their ability to enhance the immunogenicity of nasally-administered anthrax recombinant protective antigen.” Vaccine 31, no. 11 (March 1, 2013): 1480–89. https://doi.org/10.1016/j.vaccine.2013.01.012.Full Text Link to Item
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Chan, Cheryl Y., Ashley L. St John, and Soman N. Abraham. “Mast cell interleukin-10 drives localized tolerance in chronic bladder infection.” Immunity 38, no. 2 (February 21, 2013): 349–59. https://doi.org/10.1016/j.immuni.2012.10.019.Full Text Link to Item
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John, A. L. S., A. P. S. Rathore, B. Raghavan, M. L. Ng, and S. N. Abraham. “Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.” Elife 2013, no. 2 (2013). https://doi.org/10.7554/eLife.00481.001.Full Text
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Staats, Herman F., Shaun M. Kirwan, Hae Woong Choi, Christopher P. Shelburne, Soman N. Abraham, Gulice Y. C. Leung, and David Y-K Chen. “A Mast Cell Degranulation Screening Assay for the Identification of Novel Mast Cell Activating Agents.” Medchemcomm 4, no. 1 (January 1, 2013). https://doi.org/10.1039/C2MD20073B.Full Text Link to Item
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Hsia, Bethany J., Julie G. Ledford, Erin N. Potts-Kant, Vinayak S. Nikam, Njira L. Lugogo, W Michael Foster, Monica Kraft, Soman N. Abraham, and Jo Rae Wright. “Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice.” J Allergy Clin Immunol 130, no. 1 (July 2012): 205-14.e2. https://doi.org/10.1016/j.jaci.2012.03.002.Full Text Link to Item
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Chen, Ying-Lien, Jay H. Konieczka, Deborah J. Springer, Samantha E. Bowen, Jing Zhang, Fitz Gerald S. Silao, Alice Alma C. Bungay, et al. “Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata.” G3 (Bethesda) 2, no. 6 (June 2012): 675–91. https://doi.org/10.1534/g3.112.002279.Full Text Link to Item
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Chan, Cheryl Y., Ashley L. St John, and Soman N. Abraham. “Plasticity in mast cell responses during bacterial infections.” Curr Opin Microbiol 15, no. 1 (February 2012): 78–84. https://doi.org/10.1016/j.mib.2011.10.007.Full Text Link to Item
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Hsia, Bethany J., Amy M. Pastva, Charles D. Giamberardino, Erin N. Potts-Kant, W Michael Foster, Loretta G. Que, Soman N. Abraham, Jo Rae Wright, and David W. Zaas. “Increased Nitric Oxide Production Prevents Airway Hyperresponsiveness in Caveolin-1 Deficient Mice Following Endotoxin Exposure.” J Allergy Ther Suppl 1, no. 4 (January 25, 2012). https://doi.org/10.4172/2155-6121.S1-004.Full Text Link to Item
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St John, Ashley L., Cheryl Y. Chan, Herman F. Staats, Kam W. Leong, and Soman N. Abraham. “Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes.” Nat Mater 11, no. 3 (January 22, 2012): 250–57. https://doi.org/10.1038/nmat3222.Full Text Link to Item
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Wang, Sheena H., Shaun M. Kirwan, Soman N. Abraham, Herman F. Staats, and Anthony J. Hickey. “Stable dry powder formulation for nasal delivery of anthrax vaccine.” J Pharm Sci 101, no. 1 (January 2012): 31–47. https://doi.org/10.1002/jps.22742.Full Text Link to Item
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Kunder, Christian A., Ashley L. St John, and Soman N. Abraham. “Mast cell modulation of the vascular and lymphatic endothelium.” Blood 118, no. 20 (November 17, 2011): 5383–93. https://doi.org/10.1182/blood-2011-07-358432.Full Text Link to Item
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Lindsey, James Y., Koustav Ganguly, David M. Brass, Zhuowei Li, Erin N. Potts, Simone Degan, Huaiyong Chen, et al. “c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice.” Am J Respir Crit Care Med 183, no. 12 (June 15, 2011): 1644–52. https://doi.org/10.1164/rccm.201007-1157OC.Full Text Link to Item
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St John, Ashley L., Abhay P. S. Rathore, Han Yap, Mah-Lee Ng, Dean D. Metcalfe, Subhash G. Vasudevan, and Soman N. Abraham. “Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance.” Proc Natl Acad Sci U S A 108, no. 22 (May 31, 2011): 9190–95. https://doi.org/10.1073/pnas.1105079108.Full Text Link to Item
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Jin, Cong, Christopher P. Shelburne, Guojie Li, Erin N. Potts, Kristina J. Riebe, Gregory D. Sempowski, W Michael Foster, and Soman N. Abraham. “Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation.” J Clin Invest 121, no. 3 (March 2011): 941–55. https://doi.org/10.1172/JCI43584.Full Text Link to Item
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Staats, Herman F., Jeffrey R. Fielhauer, Afton L. Thompson, Alice A. Tripp, Ashley E. Sobel, Massimo Maddaloni, Soman N. Abraham, and David W. Pascual. “Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits.” Plos One 6, no. 1 (January 27, 2011): e16532. https://doi.org/10.1371/journal.pone.0016532.Full Text Link to Item
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Shelburne, Christopher P., and Soman N. Abraham. “The mast cell in innate and adaptive immunity.” Adv Exp Med Biol 716 (2011): 162–85. https://doi.org/10.1007/978-1-4419-9533-9_10.Full Text Link to Item
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Chichlowski, Maciej, Greg S. Westwood, Soman N. Abraham, and Laura P. Hale. “Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice.” Plos One 5, no. 8 (August 17, 2010): e12220. https://doi.org/10.1371/journal.pone.0012220.Full Text Open Access Copy Link to Item
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Abraham, Soman N., and Ashley L. St John. “Mast cell-orchestrated immunity to pathogens.” Nat Rev Immunol 10, no. 6 (June 2010): 440–52. https://doi.org/10.1038/nri2782.Full Text Link to Item
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Hofmann, Alison M., and Soman N. Abraham. “New roles for mast cells in pathogen defense and allergic disease.” Discov Med 9, no. 45 (February 2010): 79–83.Link to Item
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Hofmann, Alison M., and Soman N. Abraham. “New roles for mast cells in modulating allergic reactions and immunity against pathogens.” Curr Opin Immunol 21, no. 6 (December 2009): 679–86. https://doi.org/10.1016/j.coi.2009.09.007.Full Text Link to Item
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Khandelwal, Puneet, Soman N. Abraham, and Gerard Apodaca. “Cell biology and physiology of the uroepithelium.” Am J Physiol Renal Physiol 297, no. 6 (December 2009): F1477–1501. https://doi.org/10.1152/ajprenal.00327.2009.Full Text Link to Item
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St John, Ashley L., and Soman N. Abraham. “Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.” Nat Med 15, no. 11 (November 2009): 1259–65. https://doi.org/10.1038/nm.2036.Full Text Link to Item
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Zaas, David W., Zachary Swan, Bethany J. Brown, Jo Rae Wright, and Soman N. Abraham. “The expanding roles of caveolin proteins in microbial pathogenesis.” Commun Integr Biol 2, no. 6 (November 2009): 535–37. https://doi.org/10.4161/cib.2.6.9259.Full Text Link to Item
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Kunder, Christian A., Ashley L. St John, Guojie Li, Kam W. Leong, Brent Berwin, Herman F. Staats, and Soman N. Abraham. “Mast cell-derived particles deliver peripheral signals to remote lymph nodes.” J Exp Med 206, no. 11 (October 26, 2009): 2455–67. https://doi.org/10.1084/jem.20090805.Full Text Link to Item
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Shelburne, Christopher P., Hideki Nakano, Ashley L. St John, Cheryl Chan, James B. McLachlan, Michael D. Gunn, Herman F. Staats, and Soman N. Abraham. “Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues.” Cell Host Microbe 6, no. 4 (October 22, 2009): 331–42. https://doi.org/10.1016/j.chom.2009.09.004.Full Text Link to Item
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Song, Jeongmin, Brian L. Bishop, Guojie Li, Richard Grady, Ann Stapleton, and Soman N. Abraham. “TLR4-mediated expulsion of bacteria from infected bladder epithelial cells.” Proc Natl Acad Sci U S A 106, no. 35 (September 1, 2009): 14966–71. https://doi.org/10.1073/pnas.0900527106.Full Text Link to Item
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Terada, Nobuo, Nobuhiko Ohno, Sei Saitoh, Yurika Saitoh, Yasuhisa Fujii, Tetsuo Kondo, Ryohei Katoh, Cheryl Chan, Soman N. Abraham, and Shinichi Ohno. “Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells.” Cell Tissue Res 337, no. 1 (July 2009): 91–102. https://doi.org/10.1007/s00441-009-0804-z.Full Text Link to Item
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McGowen, Afton L., Laura P. Hale, Christopher P. Shelburne, Soman N. Abraham, and Herman F. Staats. “The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen.” Vaccine 27, no. 27 (June 2, 2009): 3544–52. https://doi.org/10.1016/j.vaccine.2009.03.069.Full Text Link to Item
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Zaas, David W., Zachary D. Swan, Bethany J. Brown, Guojie Li, Scott H. Randell, Simone Degan, Mary E. Sunday, Jo Rae Wright, and Soman N. Abraham. “Counteracting signaling activities in lipid rafts associated with the invasion of lung epithelial cells by Pseudomonas aeruginosa.” J Biol Chem 284, no. 15 (April 10, 2009): 9955–64. https://doi.org/10.1074/jbc.M808629200.Full Text Link to Item
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Hofmann, A. M., H. F. Staats, and S. N. Abraham. “Use of a Mast Cell Activator as a Mucosal Adjuvant for Pertussis Vaccines.” Journal of Allergy and Clinical Immunology 123, no. 2 (February 2009): S164–S164. https://doi.org/10.1016/j.jaci.2008.12.618.Full Text
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Brown, B. J., A. M. Pastva, B. Lo, W. M. Foster, P. Eu, L. G. Que, S. N. Abraham, J. R. Wright, and D. W. Zaas. “AHR Is Attenuated in Caveolin-1 Deficient Mice.” American Journal of Respiratory and Critical Care Medicine 179 (January 1, 2009).Link to Item
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Zaas, D. W., Z. D. Swan, S. H. Randell, J. R. Wright, S. M. Palmer, and S. N. Abraham. “Mast Cells Are Required for the Development of Allograft Rejection in a Murine Model of Obliterative Bronchiolitis.” American Journal of Respiratory and Critical Care Medicine 179 (January 1, 2009).Link to Item
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Terada, N., N. Ohno, S. Saitoh, Y. Saitoh, Y. Fujii, T. Kondo, R. Katoh, C. Chan, S. N. Abraham, and S. Ohno. “Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells.” Cell and Tissue Research, 2009, 1–12.
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Song, J., and S. N. Abraham. “Innate and adaptive immune responses in the urinary tract.” Eur J Clin Invest 38 Suppl 2 (October 2008): 21–28. https://doi.org/10.1111/j.1365-2362.2008.02005.x.Full Text Link to Item
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McLachlan, James B., Christopher P. Shelburne, Justin P. Hart, Salvatore V. Pizzo, Rajen Goyal, Rhea Brooking-Dixon, Herman F. Staats, and Soman N. Abraham. “Mast cell activators: a new class of highly effective vaccine adjuvants.” Nat Med 14, no. 5 (May 2008): 536–41. https://doi.org/10.1038/nm1757.Full Text Link to Item
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Song, Jeongmin, and Soman N. Abraham. “TLR-mediated immune responses in the urinary tract.” Curr Opin Microbiol 11, no. 1 (February 2008): 66–73. https://doi.org/10.1016/j.mib.2007.12.001.Full Text Link to Item
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Song, Jeongmin, Brian L. Bishop, Guojie Li, Matthew J. Duncan, and Soman N. Abraham. “TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder.” Cell Host Microbe 1, no. 4 (June 14, 2007): 287–98. https://doi.org/10.1016/j.chom.2007.05.007.Full Text Link to Item
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Bishop, Brian L., Mathew J. Duncan, Jeongmin Song, Guojie Li, David Zaas, and Soman N. Abraham. “Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells.” Nat Med 13, no. 5 (May 2007): 625–30. https://doi.org/10.1038/nm1572.Full Text Link to Item
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McGowen, Afton, Nicole A. Paraggio, Ashley E. Sobel, Shaun M. Kirwan, Chris P. Shelburne, Salvatore V. Pizzo, Soman N. Abraham, and Herman F. Staats. “The mast cell activator Compound 48/80 is a potent adjuvant for intradermally-administered anthrax protective antigen.” Journal of Immunology 178 (April 1, 2007).Link to Item
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Shelburne, Christopher P., Ashley St John, James B. McLachlau, Herman F. Staats, and Soman N. Abraham. “Mast cells enable heightened humoral immunity during infection.” Journal of Immunology 178 (April 1, 2007).Link to Item
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Song, Jeongmin, Matthew J. Duncan, Guojie Li, Cheryl Chan, Richard Grady, Ann Stapleton, and Soman N. Abraham. “A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.” Plos Pathog 3, no. 4 (April 2007): e60. https://doi.org/10.1371/journal.ppat.0030060.Full Text Link to Item
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Wang, Xiaoyuan, Anthony A. Ribeiro, Ziqiang Guan, Soman N. Abraham, and Christian R. H. Raetz. “Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase.” Proc Natl Acad Sci U S A 104, no. 10 (March 6, 2007): 4136–41. https://doi.org/10.1073/pnas.0611606104.Full Text Link to Item
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Song, J., M. J. Duncan, G. Li, C. Chan, R. Grady, A. Stapleton, and S. N. Abraham. “A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.” Plos Pathogens 3, no. 4 (2007): e60. https://doi.org/10.1371/journal.ppat.0030060.Full Text
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Shin, Jeoung-Sook, Christopher P. Shelburne, Cong Jin, E Ann LeFurgey, and Soman N. Abraham. “Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis.” J Immunol 177, no. 9 (November 1, 2006): 5791–5800. https://doi.org/10.4049/jimmunol.177.9.5791.Full Text Link to Item
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Cramer, Robert A., Michael P. Gamcsik, Rhea M. Brooking, Laura K. Najvar, William R. Kirkpatrick, Thomas F. Patterson, Carl J. Balibar, et al. “Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.” Eukaryot Cell 5, no. 6 (June 2006): 972–80. https://doi.org/10.1128/EC.00049-06.Full Text Link to Item
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Shelburne, Christopher P., James B. McLachlan, and Soman N. Abraham. “In vivo models for studying mast cell-dependent responses to bacterial infection.” Methods Mol Biol 315 (2006): 363–81. https://doi.org/10.1385/1-59259-967-2:363.Full Text Link to Item
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Zaas, David W., Matthew Duncan, Jo Rae Wright, and Soman N. Abraham. “The role of lipid rafts in the pathogenesis of bacterial infections.” Biochim Biophys Acta 1746, no. 3 (December 30, 2005): 305–13. https://doi.org/10.1016/j.bbamcr.2005.10.003.Full Text Link to Item
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Abraham, S. N., B. L. Bishop, N. Sharon, and I. Ofek. “Adhesion of bacteria to mucosal surfaces,” December 1, 2005, 35–48. https://doi.org/10.1016/B978-012491543-5/50007-3.Full Text
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Duncan, M. J., and S. N. Abraham. “Chapter 4 Lipid Raft-Mediated Entry of Bacteria into Host Cells.” Advances in Molecular and Cell Biology 36 (December 1, 2005): 79–88. https://doi.org/10.1016/S1569-2558(05)36004-8.Full Text
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Duncan, Matthew J., Elena L. Mann, Michael S. Cohen, Itzhak Ofek, Nathan Sharon, and Soman N. Abraham. “The distinct binding specificities exhibited by enterobacterial type 1 fimbriae are determined by their fimbrial shafts.” J Biol Chem 280, no. 45 (November 11, 2005): 37707–16. https://doi.org/10.1074/jbc.M501249200.Full Text Link to Item
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Malherbe, Delphine C., Veit J. Erpenbeck, Soman N. Abraham, Erika C. Crouch, Jens M. Hohlfeld, and Jo Rae Wright. “Surfactant protein D decreases pollen-induced IgE-dependent mast cell degranulation.” Am J Physiol Lung Cell Mol Physiol 289, no. 5 (November 2005): L856–66. https://doi.org/10.1152/ajplung.00009.2005.Full Text Link to Item
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Abraham, Soman N., Matthew J. Duncan, Guojie Li, and David Zaas. “Bacterial penetration of the mucosal barrier by targeting lipid rafts.” J Investig Med 53, no. 6 (September 2005): 318–21. https://doi.org/10.2310/6650.2005.53609.Full Text Link to Item
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Zaas, David W., Mathew J. Duncan, Guojie Li, Jo Rae Wright, and Soman N. Abraham. “Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2.” J Biol Chem 280, no. 6 (February 11, 2005): 4864–72. https://doi.org/10.1074/jbc.M411702200.Full Text Link to Item
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Duncan, Matthew J., Guojie Li, Jeoung-Sook Shin, Johnny L. Carson, and Soman N. Abraham. “Bacterial penetration of bladder epithelium through lipid rafts.” J Biol Chem 279, no. 18 (April 30, 2004): 18944–51. https://doi.org/10.1074/jbc.M400769200.Full Text Link to Item
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Malaviya, Rama, Teruo Ikeda, Soman N. Abraham, and Ravi Malaviya. “Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coli.” Immunol Lett 91, no. 2–3 (February 15, 2004): 103–11. https://doi.org/10.1016/j.imlet.2003.10.005.Full Text Link to Item
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Kim, J., and S. N. Abraham. “Differential mast cell response to different bacteria.” Journal of Bacteriology and Virology 34, no. 4 (January 1, 2004): 311–19.
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McLachlan, James B., Justin P. Hart, Salvatore V. Pizzo, Christopher P. Shelburne, Herman F. Staats, Michael D. Gunn, and Soman N. Abraham. “Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection.” Nat Immunol 4, no. 12 (December 2003): 1199–1205. https://doi.org/10.1038/ni1005.Full Text Link to Item
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Muñoz, Samira, Rogelio Hernández-Pando, Soman N. Abraham, and Jose Antonio Enciso. “Mast cell activation by Mycobacterium tuberculosis: mediator release and role of CD48.” J Immunol 170, no. 11 (June 1, 2003): 5590–96. https://doi.org/10.4049/jimmunol.170.11.5590.Full Text Link to Item
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Duncan, Matthew J., Jeoung-Sook Shin, and Soman N. Abraham. “Microbial entry through caveolae: variations on a theme.” Cell Microbiol 4, no. 12 (December 2002): 783–91. https://doi.org/10.1046/j.1462-5822.2002.00230.x.Full Text Link to Item
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Féger, Frédéric, Sonia Varadaradjalou, Zhimin Gao, Soman N. Abraham, and Michel Arock. “The role of mast cells in host defense and their subversion by bacterial pathogens.” Trends Immunol 23, no. 3 (March 2002): 151–58. https://doi.org/10.1016/s1471-4906(01)02156-1.Full Text Link to Item
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Shin, J. S., and S. N. Abraham. “Cell biology. Caveolae--not just craters in the cellular landscape.” Science 293, no. 5534 (August 24, 2001): 1447–48. https://doi.org/10.1126/science.1061079.Full Text Link to Item
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Shin, J. S., and S. N. Abraham. “Caveolae as portals of entry for microbes.” Microbes Infect 3, no. 9 (July 2001): 755–61. https://doi.org/10.1016/s1286-4579(01)01423-x.Full Text Link to Item
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McLachlan, J. B., and S. N. Abraham. “Studies of the multifaceted mast cell response to bacteria.” Curr Opin Microbiol 4, no. 3 (June 2001): 260–66. https://doi.org/10.1016/s1369-5274(00)00200-9.Full Text Link to Item
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Shin, J. S., and S. N. Abraham. “Glycosylphosphatidylinositol-anchored receptor-mediated bacterial endocytosis.” Fems Microbiol Lett 197, no. 2 (April 13, 2001): 131–38. https://doi.org/10.1111/j.1574-6968.2001.tb10594.x.Full Text Link to Item
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Abraham, S., J. Shin, and R. Malaviya. “Type 1 fimbriated Escherichia coli-mast cell interactions in cystitis.” J Infect Dis 183 Suppl 1 (March 1, 2001): S51–55. https://doi.org/10.1086/318853.Full Text Link to Item
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Mielcarek, N., E. H. Hörnquist, B. R. Johansson, C. Locht, S. N. Abraham, and J. Holmgren. “Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin.” Cell Microbiol 3, no. 3 (March 2001): 181–88. https://doi.org/10.1046/j.1462-5822.2001.00106.x.Full Text Link to Item
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Malaviya, R., and S. N. Abraham. “Mast cell modulation of immune responses to bacteria.” Immunol Rev 179 (February 2001): 16–24. https://doi.org/10.1034/j.1600-065x.2001.790102.x.Full Text Link to Item
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Shin, J. S., and S. N. Abraham. “Co-option of endocytic functions of cellular caveolae by pathogens.” Immunology 102, no. 1 (January 2001): 2–7. https://doi.org/10.1046/j.1365-2567.2001.01173.x.Full Text Link to Item
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Shin, J. S., Z. Gao, and S. N. Abraham. “Involvement of cellular caveolae in bacterial entry into mast cells.” Science 289, no. 5480 (August 4, 2000): 785–88. https://doi.org/10.1126/science.289.5480.785.Full Text Link to Item
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Malaviya, R., and S. N. Abraham. “Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis.” J Leukoc Biol 67, no. 6 (June 2000): 841–46. https://doi.org/10.1002/jlb.67.6.841.Full Text Link to Item
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Sharon, N., D. Hasty, and S. N. Abraham. “Molecular mechanisms for the diversification of bacterial surface lectins.” Abstracts of Papers of the American Chemical Society 219 (March 26, 2000): U240–U240.Link to Item
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Abraham, S. N., and R. Malaviya. “Mast cell modulation of the innate immune response to enterobacterial infection.” Adv Exp Med Biol 479 (2000): 91–105. https://doi.org/10.1007/0-306-46831-X_8.Full Text Link to Item
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Ofek, I., D. L. Hasty, S. N. Abraham, and N. Sharon. “Role of bacterial lectins in urinary tract infections. Molecular mechanisms for diversification of bacterial surface lectins.” Adv Exp Med Biol 485 (2000): 183–92. https://doi.org/10.1007/0-306-46840-9_25.Full Text Link to Item
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MacIvor, D. M., S. D. Shapiro, C. T. Pham, A. Belaaouaj, S. N. Abraham, and T. J. Ley. “Normal neutrophil function in cathepsin G-deficient mice.” Blood 94, no. 12 (December 15, 1999): 4282–93.Link to Item
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Abraham, S. N., and D. M. Baorto. “Nonopsonic FIMH-Mediated phagocytosis of E. coli and its possible contribution to recurrent urinary tract infections.” Advances in Cellular and Molecular Biology of Membranes and Organelles 6, no. C (December 1, 1999): 333–48. https://doi.org/10.1016/S1874-5172(99)80019-4.Full Text
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Lin, T. J., Z. Gao, M. Arock, and S. N. Abraham. “Internalization of FimH+ Escherichia coli by the human mast cell line (HMC-1 5C6) involves protein kinase C.” J Leukoc Biol 66, no. 6 (December 1999): 1031–38. https://doi.org/10.1002/jlb.66.6.1031.Full Text Link to Item
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Matatov, R., J. Goldhar, E. Skutelsky, I. Sechter, R. Perry, R. Podschun, H. Sahly, K. Thankavel, S. N. Abraham, and I. Ofek. “Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface.” Fems Microbiol Lett 179, no. 1 (October 1, 1999): 123–30. https://doi.org/10.1111/j.1574-6968.1999.tb08717.x.Full Text Link to Item
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Shin, J. S., Z. Gao, and S. N. Abraham. “Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains.” Biosci Rep 19, no. 5 (October 1999): 421–32. https://doi.org/10.1023/a:1020216323271.Full Text Link to Item
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Malaviya, R., Z. Gao, K. Thankavel, P. A. van der Merwe, and S. N. Abraham. “The mast cell tumor necrosis factor alpha response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48.” Proc Natl Acad Sci U S A 96, no. 14 (July 6, 1999): 8110–15. https://doi.org/10.1073/pnas.96.14.8110.Full Text Link to Item
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Dreskin, S. C., and S. N. Abraham. “Production of TNF-alpha by murine bone marrow derived mast cells activated by the bacterial fimbrial protein, FimH.” Clin Immunol 90, no. 3 (March 1999): 420–24. https://doi.org/10.1006/clim.1998.4657.Full Text Link to Item
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Thankavel, K., A. H. Shah, M. S. Cohen, T. Ikeda, R. G. Lorenz, R. Curtiss, and S. N. Abraham. “Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae.” J Biol Chem 274, no. 9 (February 26, 1999): 5797–5809. https://doi.org/10.1074/jbc.274.9.5797.Full Text Link to Item
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Gao, Z. M., J. S. Shin, R. Malaviya, and S. N. Abraham. “Intracellular carriage of gram negative bacteria by mast cells and its possible contribution to septic shock.” Journal of Allergy and Clinical Immunology 103, no. 1 (January 1, 1999): S42–43.Link to Item
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Lin, T. J., Z. Gao, M. Arick, and S. N. Abraham. “Bacterial up-take by human mast cells require protein kinase C.” Journal of Allergy and Clinical Immunology 103, no. 1 (January 1, 1999): S40–S40.Link to Item
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Shin, J. S., Z. M. Gao, D. Baorto, R. Malaviya, and S. N. Abraham. “Transcytosis of FimH-expressing Gram negative bacteria in mast cells by coopting cholesterol-enriched microdomains.” Journal of Allergy and Clinical Immunology 103, no. 1 (January 1, 1999): S192–93.Link to Item
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Arock, M., E. Ross, R. Lai-Kuen, G. Averlant, Z. Gao, and S. N. Abraham. “Phagocytic and tumor necrosis factor alpha response of human mast cells following exposure to gram-negative and gram-positive bacteria.” Infect Immun 66, no. 12 (December 1998): 6030–34. https://doi.org/10.1128/IAI.66.12.6030-6034.1998.Full Text Link to Item
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Abraham, S. N., and M. Arock. “Mast cells and basophils in innate immunity.” Semin Immunol 10, no. 5 (October 1998): 373–81. https://doi.org/10.1006/smim.1998.0140.Full Text Link to Item
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Malaviya, R., and S. N. Abraham. “Clinical implications of mast cell-bacteria interaction.” J Mol Med (Berl) 76, no. 9 (August 1998): 617–23. https://doi.org/10.1007/s001090050259.Full Text Link to Item
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Belaaouaj, A., R. McCarthy, M. Baumann, Z. Gao, T. J. Ley, S. N. Abraham, and S. D. Shapiro. “Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis.” Nat Med 4, no. 5 (May 1998): 615–18. https://doi.org/10.1038/nm0598-615.Full Text Link to Item
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Abraham, S. N., A. B. Jonsson, and S. Normark. “Fimbriae-mediated host-pathogen cross-talk.” Curr Opin Microbiol 1, no. 1 (February 1998): 75–81. https://doi.org/10.1016/s1369-5274(98)80145-8.Full Text Link to Item
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Malaviya, R., R. Ideda, E. Ross, and S. N. Abraham. “Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha.” Pneumologie 51, no. 8 (December 1, 1997): 869.
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Baorto, D. M., Z. Gao, R. Malaviya, M. L. Dustin, A. van der Merwe, D. M. Lublin, and S. N. Abraham. “Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic.” Nature 389, no. 6651 (October 9, 1997): 636–39. https://doi.org/10.1038/39376.Full Text Link to Item
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Abraham, S. N., and R. Malaviya. “Mast cells in infection and immunity.” Infect Immun 65, no. 9 (September 1997): 3501–8. https://doi.org/10.1128/iai.65.9.3501-3508.1997.Full Text Link to Item
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Thankavel, K., B. Madison, T. Ikeda, R. Malaviya, A. H. Shah, P. M. Arumugam, and S. N. Abraham. “Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection.” J Clin Invest 100, no. 5 (September 1, 1997): 1123–36. https://doi.org/10.1172/JCI119623.Full Text Link to Item
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Abraham, S. N., K. Thankavel, and R. Malaviya. “Mast cells as modulators of host defense in the lung.” Front Biosci 2 (February 15, 1997): d78–87. https://doi.org/10.2741/a176.Full Text Link to Item
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Malaviya, R., T. Ikeda, E. Ross, and S. N. Abraham. “Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha.” Nature 381, no. 6577 (May 2, 1996): 77–80. https://doi.org/10.1038/381077a0.Full Text Link to Item
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Malaviya, R., N. J. Twesten, E. A. Ross, S. N. Abraham, and J. D. Pfeifer. “Mast cells process bacterial Ags through a phagocytic route for class I MHC presentation to T cells.” J Immunol 156, no. 4 (February 15, 1996): 1490–96.Link to Item
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Malaviya, Ravi, Teruo Ikeda, Elaine A. Ross, Barbara A. Jakschik, and Soman N. Abraham. “Bacteria--Mast Cell Interactions in Inflammatory Disease.” Am J Ther 2, no. 10 (October 1995): 787–92. https://doi.org/10.1097/00045391-199510000-00010.Full Text Link to Item
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Jones, C. H., J. S. Pinkner, R. Roth, J. Heuser, A. V. Nicholes, S. N. Abraham, and S. J. Hultgren. “FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae.” Proc Natl Acad Sci U S A 92, no. 6 (March 14, 1995): 2081–85. https://doi.org/10.1073/pnas.92.6.2081.Full Text Link to Item
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Malaviya, R., and S. N. Abraham. “Interaction of bacteria with mast cells.” Methods Enzymol 253 (1995): 27–43. https://doi.org/10.1016/s0076-6879(95)53005-3.Full Text Link to Item
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Tewari, R., T. Ikeda, R. Malaviya, J. I. MacGregor, J. R. Little, S. J. Hultgren, and S. N. Abraham. “The PapG tip adhesin of P fimbriae protects Escherichia coli from neutrophil bactericidal activity.” Infect Immun 62, no. 12 (December 1994): 5296–5304. https://doi.org/10.1128/iai.62.12.5296-5304.1994.Full Text Link to Item
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Malaviya, R., E. Ross, B. A. Jakschik, and S. N. Abraham. “Mast cell degranulation induced by type 1 fimbriated Escherichia coli in mice.” J Clin Invest 93, no. 4 (April 1994): 1645–53. https://doi.org/10.1172/JCI117146.Full Text Link to Item
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Madison, B., I. Ofek, S. Clegg, and S. N. Abraham. “Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins.” Infect Immun 62, no. 3 (March 1994): 843–48. https://doi.org/10.1128/iai.62.3.843-848.1994.Full Text Link to Item
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Malaviya, R., E. A. Ross, J. I. MacGregor, T. Ikeda, J. R. Little, B. A. Jakschik, and S. N. Abraham. “Mast cell phagocytosis of FimH-expressing enterobacteria.” J Immunol 152, no. 4 (February 15, 1994): 1907–14.Link to Item
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Abraham, S. N. “Bactericidal activity of mast cells.” Gastroenterology 107, no. 3 (January 1, 1994): 894. https://doi.org/10.1016/0016-5085(94)90145-7.Full Text
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Barrett, K. E., and S. N. Abraham. “Bactericidal activity of mast cells.” Gastroenterology 107, no. 3 (1994): 893–94.
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Jones, C. H., J. S. Pinkner, A. V. Nicholes, L. N. Slonim, S. N. Abraham, and S. J. Hultgren. “FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria.” Proc Natl Acad Sci U S A 90, no. 18 (September 15, 1993): 8397–8401. https://doi.org/10.1073/pnas.90.18.8397.Full Text Link to Item
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Hultgren, S. J., S. Abraham, M. Caparon, P. Falk, J. W. St Geme, and S. Normark. “Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition.” Cell 73, no. 5 (June 4, 1993): 887–901. https://doi.org/10.1016/0092-8674(93)90269-v.Full Text Link to Item
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Tewari, R., J. I. MacGregor, T. Ikeda, J. R. Little, S. J. Hultgren, and S. N. Abraham. “Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli.” J Biol Chem 268, no. 4 (February 5, 1993): 3009–15.Link to Item
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Ponniah, S., S. N. Abraham, and R. O. Endres. “T-cell-independent stimulation of immunoglobulin secretion in resting human B lymphocytes by the mannose-specific adhesin of Escherichia coli type 1 fimbriae.” Infect Immun 60, no. 12 (December 1992): 5197–5203. https://doi.org/10.1128/iai.60.12.5197-5203.1992.Full Text Link to Item
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Sokurenko, E. V., H. S. Courtney, S. N. Abraham, P. Klemm, and D. L. Hasty. “Functional heterogeneity of type 1 fimbriae of Escherichia coli.” Infect Immun 60, no. 11 (November 1992): 4709–19. https://doi.org/10.1128/iai.60.11.4709-4719.1992.Full Text Link to Item
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Abraham, S. N., M. Land, S. Ponniah, R. Endres, D. L. Hasty, and J. P. Babu. “Glycerol-induced unraveling of the tight helical conformation of Escherichia coli type 1 fimbriae.” J Bacteriol 174, no. 15 (August 1992): 5145–48. https://doi.org/10.1128/jb.174.15.5145-5148.1992.Full Text Link to Item
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Ponniah, S., R. O. Endres, D. L. Hasty, and S. N. Abraham. “Fragmentation of Escherichia coli type 1 fimbriae exposes cryptic D-mannose-binding sites.” J Bacteriol 173, no. 13 (July 1991): 4195–4202. https://doi.org/10.1128/jb.173.13.4195-4202.1991.Full Text Link to Item
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Babu, J. P., M. K. Dabbous, and S. N. Abraham. “Isolation and characterization of a 180-kiloDalton salivary glycoprotein which mediates the attachment of Actinomyces naeslundii to human buccal epithelial cells.” J Periodontal Res 26, no. 2 (March 1991): 97–106. https://doi.org/10.1111/j.1600-0765.1991.tb01632.x.Full Text Link to Item
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Hultgren, S. J., S. Normark, and S. N. Abraham. “Chaperone-assisted assembly and molecular architecture of adhesive pili.” Annu Rev Microbiol 45 (1991): 383–415. https://doi.org/10.1146/annurev.mi.45.100191.002123.Full Text Link to Item
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Christensen, G. D., L. M. Baddour, B. M. Madison, J. T. Parisi, S. N. Abraham, D. L. Hasty, J. H. Lowrance, J. A. Josephs, and W. A. Simpson. “Colonial morphology of staphylococci on Memphis agar: phase variation of slime production, resistance to beta-lactam antibiotics, and virulence.” J Infect Dis 161, no. 6 (June 1990): 1153–69. https://doi.org/10.1093/infdis/161.6.1153.Full Text Link to Item
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Kienzle, T. E., S. Abraham, B. G. Hogue, and D. A. Brian. “Structure and orientation of expressed bovine coronavirus hemagglutinin-esterase protein.” Journal of Virology 64, no. 4 (1990): 1834–38.
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Ponniah, S., S. N. Abraham, M. E. Dockter, C. D. Wall, and R. O. Endres. “Mitogenic stimulation of human B lymphocytes by the mannose-specific adhesin on Escherichia coli type 1 fimbriae.” J Immunol 142, no. 3 (February 1, 1989): 992–98.Link to Item
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Abraham, S. N., D. Sun, J. B. Dale, and E. H. Beachey. “Conservation of the D-mannose-adhesion protein among type 1 fimbriated members of the family Enterobacteriaceae.” Nature 336, no. 6200 (December 15, 1988): 682–84. https://doi.org/10.1038/336682a0.Full Text Link to Item
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Beachey, E. H., C. S. Giampapa, and S. N. Abraham. “Bacterial adherence. Adhesin receptor-mediated attachment of pathogenic bacteria to mucosal surfaces.” Am Rev Respir Dis 138, no. 6 Pt 2 (December 1988): S45–48. https://doi.org/10.1164/ajrccm/138.6_Pt_2.S45.Full Text Link to Item
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Sun, D., S. N. Abraham, and E. H. Beachey. “Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli.” Antimicrob Agents Chemother 32, no. 8 (August 1988): 1274–77. https://doi.org/10.1128/AAC.32.8.1274.Full Text Link to Item
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Abraham, S. N., J. D. Goguen, and E. H. Beachey. “Hyperadhesive mutant of type 1-fimbriated Escherichia coli associated with formation of FimH organelles (fimbriosomes).” Infect Immun 56, no. 5 (May 1988): 1023–29. https://doi.org/10.1128/iai.56.5.1023-1029.1988.Full Text Link to Item
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Giampapa, C. S., S. N. Abraham, T. M. Chiang, and E. H. Beachey. “Isolation and characterization of a receptor for type 1 fimbriae of Escherichia coli from guinea pig erythrocytes.” J Biol Chem 263, no. 11 (April 15, 1988): 5362–67.Link to Item
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Abraham, S. N., and E. H. Beachey. “Binding of bacteria to mucosal surfaces.” Monogr Allergy 24 (1988): 38–43.Link to Item
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Abraham, S. N., J. D. Goguen, D. Sun, P. Klemm, and E. H. Beachey. “Identification of two ancillary subunits of Escherichia coli type 1 fimbriae by using antibodies against synthetic oligopeptides of fim gene products.” J Bacteriol 169, no. 12 (December 1987): 5530–36. https://doi.org/10.1128/jb.169.12.5530-5536.1987.Full Text Link to Item
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Abraham, S. N., and E. H. Beachey. “Assembly of a chemically synthesized peptide of Escherichia coli type 1 fimbriae into fimbria-like antigenic structures.” J Bacteriol 169, no. 6 (June 1987): 2460–65. https://doi.org/10.1128/jb.169.6.2460-2465.1987.Full Text Link to Item
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Schifferli, D. M., S. N. Abraham, and E. H. Beachey. “Use of monoclonal antibodies to probe subunit- and polymer-specific epitopes of 987P fimbriae of Escherichia coli.” Infect Immun 55, no. 4 (April 1987): 923–30. https://doi.org/10.1128/iai.55.4.923-930.1987.Full Text Link to Item
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Babu, J. P., S. N. Abraham, M. K. Dabbous, and E. H. Beachey. “Interaction of a 60-kilodalton D-mannose-containing salivary glycoprotein with type 1 fimbriae of Escherichia coli.” Infect Immun 54, no. 1 (October 1986): 104–8. https://doi.org/10.1128/iai.54.1.104-108.1986.Full Text Link to Item
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Schifferli, D. M., S. N. Abraham, and E. H. Beachey. “Influence of trimethoprim and sulfamethoxazole on the synthesis, expression, and function of type 1 fimbriae of Escherichia coli.” J Infect Dis 154, no. 3 (September 1986): 490–96. https://doi.org/10.1093/infdis/154.3.490.Full Text Link to Item
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Minion, F. C., S. N. Abraham, E. H. Beachey, and J. D. Goguen. “The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit.” J Bacteriol 165, no. 3 (March 1986): 1033–36. https://doi.org/10.1128/jb.165.3.1033-1036.1986.Full Text Link to Item
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Abraham, S. N., J. P. Babu, C. S. Giampapa, D. L. Hasty, W. A. Simpson, and E. H. Beachey. “Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors.” Infect Immun 48, no. 3 (June 1985): 625–28. https://doi.org/10.1128/iai.48.3.625-628.1985.Full Text Link to Item
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Abraham, S. N., D. L. Hasty, W. A. Simpson, and E. H. Beachey. “Antiadhesive properties of a quaternary structure-specific hybridoma antibody against type 1 fimbriae of Escherichia coli.” J Exp Med 158, no. 4 (October 1, 1983): 1114–28. https://doi.org/10.1084/jem.158.4.1114.Full Text Link to Item
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Abraham, S. N., E. H. Beachey, and W. A. Simpson. “Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells.” Infect Immun 41, no. 3 (September 1983): 1261–68. https://doi.org/10.1128/iai.41.3.1261-1268.1983.Full Text Link to Item
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Perussia, B., S. Starr, S. Abraham, V. Fanning, and G. Trinchieri. “Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1.” J Immunol 130, no. 5 (May 1983): 2133–41.Link to Item
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Parry, S. H., S. Boonchai, S. N. Abraham, J. M. Salter, D. M. Rooke, J. M. Simpson, A. J. Bint, and M. Sussman. “A comparative study of the mannose-resistant and mannose-sensitive haemagglutinins of Escherichia coli isolated from urinary tract infections.” Infection 11, no. 2 (1983): 123–28. https://doi.org/10.1007/BF01641080.Full Text Link to Item
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Abraham, S. N., and R. V. Lawande. “Incidence of free-living amoebae in the nasal passages of local population in Zaria, Nigeria.” J Trop Med Hyg 85, no. 5 (October 1982): 217–22.Link to Item
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Parry, S. H., S. N. Abraham, I. M. Feavers, M. Lee, M. R. Jones, A. J. Bint, and M. Sussman. “Urinary tract infection due to laboratory-acquired Escherichia coli: relation to virulence.” Br Med J (Clin Res Ed) 282, no. 6268 (March 21, 1981): 949–50. https://doi.org/10.1136/bmj.282.6268.949-a.Full Text Link to Item
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Lawande, R. V., S. N. Abraham, I. John, and L. J. Egler. “Recovery of soil Amebas from the nasal passages of children during the dusty harmattan period in Zaria.” Am J Clin Pathol 71, no. 2 (February 1979): 201–3. https://doi.org/10.1093/ajcp/71.2.201.Full Text Link to Item
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Book Sections
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Johnson-Weaver, Brandi, Soman Abraham, and Herman Staats. “Innate Immunity based Mucosal Modulators and Adjuvants.” In Mucosal Vaccines, edited by Hiroshi Kiyono and David Pascual, 167–83. Academic Press, 2020. https://doi.org/10.1016/C2016-0-00017-7.Full Text Link to Item
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Choi, Hae Woong, Brandi Johnson-Weaver, Herman Staats, and Soman Abraham. “Mast Cells For the Control of Mucosal Immunity.” In Mucosal Vaccines Innovation for Preventing Infectious Diseases, edited by Hiroshi Kiyono and David Pascual. Academic Press, 2019.Link to Item
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Johnson-Weaver, Brandi, Soman Abraham, and Herman Staats. “Innate Immunity-Based Mucosal Modulators and Adjuvants.” In Mucosal Vaccines Innovation for Preventing Infectious Diseases, edited by Hiroshi Kiyono and David Pascual. Academic Press, 2019.Link to Item
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Hayes, B. W., and S. N. Abraham. “Innate immune responses to bladder infection.” In Urinary Tract Infections: Molecular Pathogenesis and Clinical Management, 555–64, 2016. https://doi.org/10.1128/9781555817404.ch22.Full Text
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Abraham, S. N., N. Sharon, I. Ofek, and J. D. Schwartzman. “Adhesion and Colonization.” In Molecular Medical Microbiology, 409–21, 2014. https://doi.org/10.1016/B978-0-12-397169-2.00024-X.Full Text
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Ofek, I., E. A. Bayer, and S. N. Abraham. “Bacterial adhesion.” In The Prokaryotes: Human Microbiology, 107–23, 2013. https://doi.org/10.1007/978-3-642-30144-5_50.Full Text
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Conference Papers
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Yang, Bin, Jutamas Suwanpradid, Roberto Sanchez-Lagunes, Hae Woong Choi, Peter Hoang, Donghai Wang, Soman N. Abraham, and Amanda S. MacLeod. “IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense.” In J Invest Dermatol, 137:1166–75, 2017. https://doi.org/10.1016/j.jid.2017.01.010.Full Text Open Access Copy Link to Item
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Kulis, Michael D., Caitlin Burk, Xiaohong Yue, Huamei Zhang, Pamela H. Steele, Deanna K. Hamilton, Ayeshia Beavers, et al. “Basophil Hyporesponsiveness Following Six Months of Peanut Oral Immunotherapy (OIT) Is Associated with Suppression of Syk Phosphorylation.” In Journal of Allergy and Clinical Immunology, 135:AB24–AB24. Elsevier BV, 2015. https://doi.org/10.1016/j.jaci.2014.12.1010.Full Text
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Choi, Hae Woong, Rhea Brooking, Subham Neupane, Chul-Jin Lee, Edward Miao, Herman F. Staats, and Soman N. Abraham. “Salmonella Typhimurium Impedes Innate Immunity With a Mast Cell-Suppressing Tyrosine Phosphatase Sptp.” In Journal of Allergy and Clinical Immunology, 133:AB247–AB247. Elsevier BV, 2014. https://doi.org/10.1016/j.jaci.2013.12.879.Full Text
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Johnson, B. T., M. Kulis, S. N. Abraham, A. W. Burks, and H. F. Staats. “Nasal Immunization with Peanut Antigen and The Cationic Peptide Adjuvant Mastoparan 7 Induces Serum Humoral Immunity That Protects Peanut Allergic Mice Against Systemic Anaphylaxis.” In Journal of Allergy and Clinical Immunology, 129:AB176–AB176. Elsevier BV, 2012. https://doi.org/10.1016/j.jaci.2011.12.221.Full Text
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Lindsey, J. Y., K. Ganguly, D. M. Brass, Z. Li, E. N. Potts, S. Degan, H. Chen, et al. “C-KIT Is Necessary For Protection From Emphysema-Like Disease In Mice.” In American Journal of Respiratory and Critical Care Medicine, Vol. 183. AMER THORACIC SOC, 2011.Link to Item
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Hofmann, A. M., C. Jin, H. F. Staats, and S. N. Abraham. “An In Vitro Model of Mast Cell Desensitization.” In Journal of Allergy and Clinical Immunology, 125:AB179–AB179. Elsevier BV, 2010. https://doi.org/10.1016/j.jaci.2009.12.702.Full Text
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Hofmann, A. M., H. F. Staats, and S. N. Abraham. “Mast cell activator as a mucosal adjuvant in intranasal pertussis vaccine.” In Clinical and Experimental Allergy, 39:1940–1940. WILEY-BLACKWELL PUBLISHING, INC, 2009.Link to Item
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- Teaching & Mentoring
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Recent Courses
- PATHOL 293: Research Independent Study 2023
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- PATHOL 855S: Graduate Seminar in Pathology 2023
- PATHOL 293: Research Independent Study 2022
- PATHOL 793: Research Independent Study 2022
- PATHOL 855S: Graduate Seminar in Pathology 2022
- PATHOL 293: Research Independent Study 2021
- PATHOL 785: Molecular Aspects of Disease 2021
- PATHOL 793: Research Independent Study 2021
- PATHOL 855S: Graduate Seminar in Pathology 2021
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