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Sonal Deshpande

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering

Current Duke Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2024 - Present Biomedical Engineering, Pratt School of Engineering

Recent Scholarly Works


All-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery.

Journal article Advanced science (Weinheim, Baden-Wurttemberg, Germany) · March 2026 Poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) is a stealth polymer that does not exhibit polyethylene glycol (PEG) antigenicity. Herein, we engineered self-assembling nanoparticles composed entirely of POEGMA by designing AB diblock copol ... Full text Cite

Intrinsically disordered protein coating for oral delivery of peptide drugs

Journal article Cell Biomaterials · January 1, 2026 Advancing oral delivery of peptide therapeutics requires innovative materials that overcome gastrointestinal barriers. We introduce an engineered synthetic intrinsically disordered protein (SynIDP) that self-assembles into an enteric coating, encapsulating ... Full text Cite

Nonfouling Coatings from Synthetic Intrinsically Disordered Proteins.

Journal article Small (Weinheim an der Bergstrasse, Germany) · August 2025 The antifouling performance of a previously developed triblock protein, B-M-E is optimized, that self-assembles on gold surfaces to form a nonfouling layer by modifying the sequence of its E block. In this protein, B is a gold-binding domain, M is a trimer ... Full text Cite
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Recent Grants


Next Generation Stealth Lipid for the Delivery of mRNA

ResearchResearch Scientist · Awarded by Gateway Bio, Inc. · 2025 - 2026

Liquid Brachytherapy in a Porcine Model to Treat Pancreatic Cancer

ResearchResearch Scientist · Awarded by North Carolina Biotechnology Center · 2024 - 2025

Injectable PEG-like Conjugate for Sustained Delivery of a Peptide Drug for Type 2 Diabetes Treatment

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2020 - 2025

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Education


Indian Institute of Technology, Delhi (India) · 2018 Ph.D.