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Sonal Deshpande

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering

Current Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2024 - Present Biomedical Engineering, Pratt School of Engineering

Recent Publications


Nonfouling Coatings from Synthetic Intrinsically Disordered Proteins.

Journal Article Small (Weinheim an der Bergstrasse, Germany) · August 2025 The antifouling performance of a previously developed triblock protein, B-M-E is optimized, that self-assembles on gold surfaces to form a nonfouling layer by modifying the sequence of its E block. In this protein, B is a gold-binding domain, M is a trimer ... Full text Cite

Spatiotemporal Control of IL-12 Delivery Improves Its Efficacy in Treatment of Solid Tumors

Journal Article Advanced Therapeutics · August 1, 2025 Despite renewed interest in IL-12 as a cancer immunotherapy due to its ability to stimulate the adaptive immune system, its short half-life and narrow therapeutic window continues to present challenges for effective delivery. Previous studies with IL-12 ha ... Full text Cite

Synthetic biomolecular condensates enhance translation from a target mRNA in living cells.

Journal Article Nat Chem · March 2025 Biomolecular condensates composed of proteins and RNA are one approach by which cells regulate post-transcriptional gene expression. Their formation typically involves the phase separation of intrinsically disordered proteins with a target mRNA, sequesteri ... Full text Link to item Cite
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Recent Grants


Next Generation Stealth Lipid for the Delivery of mRNA

ResearchResearch Scientist · Awarded by Gateway Bio, Inc. · 2025 - 2026

Liquid Brachytherapy in a Porcine Model to Treat Pancreatic Cancer

ResearchResearch Scientist · Awarded by North Carolina Biotechnology Center · 2024 - 2025

Injectable PEG-like Conjugate for Sustained Delivery of a Peptide Drug for Type 2 Diabetes Treatment

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2020 - 2025

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Education, Training & Certifications


Indian Institute of Technology, Delhi (India) · 2018 Ph.D.