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Sophia Dorcheva Sarafova

Adjunct Associate Professor in the Department of Immunology
Integrative Immunobiology
Immunology, Box 3010, Durham, NC 27710

Current Appointments & Affiliations


Adjunct Associate Professor in the Department of Immunology · 2012 - Present Integrative Immunobiology, Basic Science Departments

Recent Publications


Verification of the T-cell developmental stage at which RLM11 and AKR1G1 thymoma cell lines are arrested 9062

Conference The Journal of Immunology · November 1, 2025 Abstract Description A variety of cell lines are used routinely for in vitro studies as fair representation of developmental st ... Full text Cite

A conserved element in the first intron of Cd4 has a lineage specific, TCR signal-responsive, canonical enhancer function that matches the timing of cell surface CD4 upregulation required to prevent lineage choice error.

Journal Article Front Immunol · 2024 INTRODUCTION: The regulation of Cd4 expression during T-cell development and immune responses is essential for proper lineage commitment and function in the periphery. However, the mechanisms of genetic and epigenetic regulation are complex, and their inte ... Full text Open Access Link to item Cite
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Education, Training & Certifications


Columbia University · 2000 Ph.D.