Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship in Infectious Diseases, Medicine, Duke University School of Medicine 2014 - 2018
  • Internal Medicine Residency, University of California - Los Angeles 2011 - 2014
  • M.D., University of California, Los Angeles, David Geffen School of Medicine 2011
  • Ph.D., California Institute of Technology 2009
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2019 - 2020
  • Medical Instructor in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2018 - 2019
• Recognition
• 

  In the News

  • JUN 1, 2021

    School of Medicine

    Six School of Medicine Physician-Scientists selected to receive Strong Start Awards
• Research
• 

  Selected Grants

  • Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint (K23) awarded by National Institutes of Health 2022 - 2027
  • Neutrophil Activation Phenotypes in Healthy Subjects and Implications for Bacterial Clearance awarded by National Institutes of Health 2020 - 2022
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Maskarinec, Stacey A., Margaret McKelvy, Kimberly Boyle, Halie Hotchkiss, Madelaine E. Duarte, Bechtler Addison, Nicholas Amato, Sanjay Khandelwal, Gowthami M. Arepally, and Grace M. Lee. “Neutrophil functional heterogeneity is a fixed phenotype and is associated with distinct gene expression profiles.” J Leukoc Biol, August 2, 2022. https://doi.org/10.1002/JLB.4A0322-164R.
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    • Sinclair, Matthew R., Maria Souli, Felicia Ruffin, Lawrence P. Park, Michael Dagher, Emily M. Eichenberger, Stacey A. Maskarinec, et al. “Staphylococcus aureus Bacteremia Among Patients Receiving Maintenance Hemodialysis: Trends in Clinical Characteristics and Outcomes.” Am J Kidney Dis 79, no. 3 (March 2022): 393-403.e1. https://doi.org/10.1053/j.ajkd.2021.06.018.
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    • Eichenberger, Emily M., Felicia Ruffin, Batu Sharma-Kuinkel, Michael Dagher, Lawrence Park, Celia Kohler, Matthew R. Sinclair, Stacey A. Maskarinec, and Vance G. Fowler. “Bacterial genotype and clinical outcomes in solid organ transplant recipients with Staphylococcus aureus bacteremia.” Transpl Infect Dis 23, no. 6 (December 2021): e13730. https://doi.org/10.1111/tid.13730.
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    • Eichenberger, Emily M., Michael Dagher, Matthew R. Sinclair, Stacey A. Maskarinec, Vance G. Fowler, and Jerome J. Federspiel. “Infective endocarditis and solid organ transplantation: Only worse outcomes during initial transplantation hospitalization.” Am Heart J 240 (October 2021): 63–72. https://doi.org/10.1016/j.ahj.2021.06.007.
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    • Eichenberger, Emily M., Felicia Ruffin, Michael Dagher, Reginald Lerebours, Sin-Ho Jung, Batu Sharma-Kuinkel, Andrew N. Macintyre, et al. “Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: Acute phase cytokines and outcomes in a prospective, matched cohort study.” Am J Transplant 21, no. 6 (June 2021): 2113–22. https://doi.org/10.1111/ajt.16388.
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    • Thaden, Joshua T., and Stacey A. Maskarinec. “When two for the price of one isn't a bargain: estimating prevalence and microbiology of bacterial co-infections in patients with COVID-19.” Clin Microbiol Infect 26, no. 12 (December 2020): 1602–3. https://doi.org/10.1016/j.cmi.2020.09.002.
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    • Mourad, Ahmad, Sana Arif, Muath Bishawi, Carmelo Milano, Rachel A. Miller, and Stacey A. Maskarinec. “Surgical infection prophylaxis prior to left ventricular assist device implantation: A survey of clinical practice.” J Card Surg 35, no. 10 (October 2020): 2672–78. https://doi.org/10.1111/jocs.14882.
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    • Maskarinec, S. A., L. P. Park, F. Ruffin, N. A. Turner, N. Patel, E. M. Eichenberger, D. van Duin, T. Lodise, V. G. Fowler, and J. T. Thaden. “Positive follow-up blood cultures identify high mortality risk among patients with Gram-negative bacteraemia.” Clin Microbiol Infect 26, no. 7 (July 2020): 904–10. https://doi.org/10.1016/j.cmi.2020.01.025.
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    • Cao, Yi, Alessander O. Guimaraes, Melicent C. Peck, Oleg Mayba, Felicia Ruffin, Kyu Hong, Montserrat Carrasco-Triguero, Vance G. Fowler, Stacey A. Maskarinec, and Carrie M. Rosenberger. “Risk stratification biomarkers for Staphylococcus aureus bacteraemia.” Clin Transl Immunology 9, no. 2 (2020): e1110. https://doi.org/10.1002/cti2.1110.
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    • Souli, Maria, Felicia Ruffin, Seong-Ho Choi, Lawrence P. Park, Shengli Gao, Nicholas Christopoulos Lent, Batu K. Sharma-Kuinkel, et al. “Changing Characteristics of Staphylococcus aureus Bacteremia: Results From a 21-Year, Prospective, Longitudinal Study.” Clin Infect Dis 69, no. 11 (November 13, 2019): 1868–77. https://doi.org/10.1093/cid/ciz112.
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    • Guimaraes, Alessander O., Yi Cao, Kyu Hong, Oleg Mayba, Melicent C. Peck, Johnny Gutierrez, Felicia Ruffin, et al. “A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.” Clin Infect Dis 68, no. 9 (April 24, 2019): 1502–11. https://doi.org/10.1093/cid/ciy739.
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    • Guimaraes, Alessander O., Johnny Gutierrez, Stacey A. Maskarinec, Yi Cao, Kyu Hong, Felicia Ruffin, Montserrat Carrasco-Triguero, et al. “Prognostic Power of Pathogen Cell-Free DNA in Staphylococcus aureus Bacteremia.” Open Forum Infect Dis 6, no. 4 (April 2019): ofz126. https://doi.org/10.1093/ofid/ofz126.
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    • Turner, Nicholas A., Batu K. Sharma-Kuinkel, Stacey A. Maskarinec, Emily M. Eichenberger, Pratik P. Shah, Manuela Carugati, Thomas L. Holland, and Vance G. Fowler. “Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research.” Nat Rev Microbiol 17, no. 4 (April 2019): 203–18. https://doi.org/10.1038/s41579-018-0147-4.
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    • Maskarinec, Stacey A., Zehra Parlak, Qing Tu, Vrad Levering, Stefan Zauscher, Gabriel P. López, Vance G. Fowler, and John R. Perfect. “On-demand release of Candida albicans biofilms from urinary catheters by mechanical surface deformation.” Biofouling 34, no. 6 (July 2018): 595–604. https://doi.org/10.1080/08927014.2018.1474461.
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    • Miao, Yi, Jennifer L. Tenor, Dena L. Toffaletti, Stacey A. Maskarinec, Jiuyu Liu, Richard E. Lee, John R. Perfect, and Richard G. Brennan. “Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.” Mbio 8, no. 4 (July 25, 2017). https://doi.org/10.1128/mBio.00643-17.
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    • Thaden, Joshua T., Lawrence P. Park, Stacey A. Maskarinec, Felicia Ruffin, Vance G. Fowler, and David van Duin. “Results from a 13-Year Prospective Cohort Study Show Increased Mortality Associated with Bloodstream Infections Caused by Pseudomonas aeruginosa Compared to Other Bacteria.” Antimicrob Agents Chemother 61, no. 6 (June 2017). https://doi.org/10.1128/AAC.02671-16.
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    • Cyr, D. D., A. S. Allen, G. -. J. Du, F. Ruffin, C. Adams, J. T. Thaden, S. A. Maskarinec, et al. “Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping.” Genes Immun 18, no. 2 (March 2017): 95–99. https://doi.org/10.1038/gene.2017.6.
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    • Thaden, Joshua T., Yanhong Li, Felicia Ruffin, Stacey A. Maskarinec, Jonathan M. Hill-Rorie, Lisa C. Wanda, Shelby D. Reed, and Vance G. Fowler. “Increased Costs Associated with Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Bacteria Are Due Primarily to Patients with Hospital-Acquired Infections.” Antimicrob Agents Chemother 61, no. 3 (March 2017). https://doi.org/10.1128/AAC.01709-16.
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    • Maskarinec, Stacey A., Joshua T. Thaden, Derek D. Cyr, Felicia Ruffin, Maria Souli, and Vance G. Fowler. “The Risk of Cardiac Device-Related Infection in Bacteremic Patients Is Species Specific: Results of a 12-Year Prospective Cohort.” Open Forum Infect Dis 4, no. 3 (2017): ofx132. https://doi.org/10.1093/ofid/ofx132.
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    • Maskarinec, Stacey A., Melissa D. Johnson, and John R. Perfect. “Genetic Susceptibility to Fungal Infections: What is in the Genes?” Curr Clin Microbiol Rep 3, no. 2 (June 2016): 81–91. https://doi.org/10.1007/s40588-016-0037-3.
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    • Maskarinec, Stacey A., and Vance G. Fowler. “Persistent Rash in a Patient Receiving Total Parenteral Nutrition.” Jama 315, no. 20 (May 24, 2016): 2223–24. https://doi.org/10.1001/jama.2016.4154.
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    • Qi, Robert, Hwang-Soo Joo, Batu Sharma-Kuinkel, Nicholas R. Berlon, Lawrence Park, Chih-Lung Fu, Julia A. Messina, et al. “Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus.” J Infect 72, no. 3 (March 2016): 302–8. https://doi.org/10.1016/j.jinf.2015.11.002.
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    • Berlon, Nicholas R., Robert Qi, Batu K. Sharma-Kuinkel, Hwang-Soo Joo, Lawrence P. Park, Dennis George, Joshua T. Thaden, et al. “Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins.” J Infect 71, no. 4 (October 2015): 447–57. https://doi.org/10.1016/j.jinf.2015.06.005.
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    • Franck, Christian, Stacey A. Maskarinec, David A. Tirrell, and Guruswami Ravichandran. “Three-dimensional traction force microscopy: a new tool for quantifying cell-matrix interactions.” Plos One 6, no. 3 (March 29, 2011): e17833. https://doi.org/10.1371/journal.pone.0017833.
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    • Maskarinec, Stacey A., Christian Franck, David A. Tirrell, and Guruswami Ravichandran. “Quantifying cellular traction forces in three dimensions.” Proc Natl Acad Sci U S A 106, no. 52 (December 29, 2009): 22108–13. https://doi.org/10.1073/pnas.0904565106.
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    • Nowatzki, P. J., C. Franck, S. A. Maskarinec, G. Ravichandran, and D. A. Tirrell. “Mechanically tunable thin films of photosensitive artificial proteins: Preparation and characterization by nanoindentation.” Macromolecules 41, no. 5 (March 11, 2008): 1839–45. https://doi.org/10.1021/ma071717a.
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    • Franck, C., S. Hong, S. A. Maskarinec, D. A. Tirrell, and G. Ravichandran. “Three-dimensional full-field measurements of large deformations in soft materials using confocal microscopy and digital volume correlation.” Experimental Mechanics 47, no. 3 (June 1, 2007): 427–38. https://doi.org/10.1007/s11340-007-9037-9.
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    • Carrico, Isaac S., Stacey A. Maskarinec, Sarah C. Heilshorn, Marissa L. Mock, Julie C. Liu, Paul J. Nowatzki, Christian Franck, Guruswami Ravichandran, and David A. Tirrell. “Lithographic patterning of photoreactive cell-adhesive proteins.” J Am Chem Soc 129, no. 16 (April 25, 2007): 4874–75. https://doi.org/10.1021/ja070200b.
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    • Wu, G., S. L. Frey, S. A. Maskarinec, and K. Y. C. Lee. “Triblock copolymer as an effective membrane-sealing material.” Mrs Bulletin 31, no. 7 (January 1, 2006): 532–35. https://doi.org/10.1557/mrs2006.138.
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    • Maskarinec, Stacey A., Guohui Wu, and Ka Yee C. Lee. “Membrane sealing by polymers.” Ann N Y Acad Sci 1066 (December 2005): 310–20. https://doi.org/10.1196/annals.1363.018.
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    • Maskarinec, Stacey A., and David A. Tirrell. “Protein engineering approaches to biomaterials design.” Curr Opin Biotechnol 16, no. 4 (August 2005): 422–26. https://doi.org/10.1016/j.copbio.2005.06.009.
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    • Maskarinec, S. A., and K. Y. C. Lee. “Comparative study of Poloxamer insertion into lipid monolayers.” Langmuir 19, no. 5 (March 4, 2003): 1809–15. https://doi.org/10.1021/la026175z.
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    • Maskarinec, Stacey A., Jürgen Hannig, Raphael C. Lee, and Ka Yee C. Lee. “Direct observation of poloxamer 188 insertion into lipid monolayers.” Biophys J 82, no. 3 (March 2002): 1453–59. https://doi.org/10.1016/S0006-3495(02)75499-4.
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    • Maskarinec, S. A., J. Hannig, K. Y. C. Lee, and R. C. Lee. “Membrane sealing copolymer surfactant poloxamer 188 inserts into lipid monolayers at reduced surface pressures.” Annals of Biomedical Engineering 28, no. SUPPL. 1 (December 1, 2000).

  • Book Sections

    • Franck, C., and S. A. Maskarinec. “Quantifying cell-matrix deformations in three dimensions.” In Mechanobiology of Cell-Cell and Cell-Matrix Interactions, 211–32, 2011. https://doi.org/10.1007/978-1-4419-8083-0_10.
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  • Conference Papers

    • Notbohm, J., J. H. Kim, C. Franck, S. Maskarinec, D. Tirrell, A. Asthagiri, and G. Ravichandran. “Three-dimensional traction force microscopy for studying cellular interactions with biomaterials.” In Procedia Iutam, 4:144–50, 2012. https://doi.org/10.1016/j.piutam.2012.05.016.
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