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Stacy M. Horner

Associate Professor in Integrative Immunobiology
Integrative Immunobiology
213 Research Drive, Room 0034 CARL Bldg, Durham, NC 27710


Studying the RNA biology, cell biology, and immunology of RNA virus infection

Our lab studies the molecular mechanisms that regulate RNA virus-host interactions. We focus primarily on viruses in the Flaviviridae family of viruses, including dengue virus (DENV), Zika virus (ZIKV), and hepatitis C virus (HCV). Our research is focused on defining (1) how these viruses replicate, (2) the mechanisms that regulate antiviral innate immunity to these viruses, and (3) RNA regulatory controls to both of these processes. Our lab has pioneered approaches to how the RNA modification m6A regulates viral infection, antiviral innate immunity and the host response to virus infection. Our long-term goal is to discover the necessary mechanistic and functional information to guide future development of new strategies for virus treatment and prevention.

Lab Website

Current Appointments & Affiliations

Associate Professor in Integrative Immunobiology · 2022 - Present Integrative Immunobiology, Basic Science Departments
Associate Professor of Medicine · 2021 - Present Medicine, Infectious Diseases, Medicine
Associate Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Associate Professor of Molecular Genetics and Microbiology · 2022 - Present Molecular Genetics and Microbiology, Basic Science Departments
Member of the Duke Cancer Institute · 2014 - Present Duke Cancer Institute, Institutes and Centers
Associate of the Duke Initiative for Science & Society · 2018 - Present Duke Science & Society, Initiatives

Education, Training & Certifications

Yale University · 2007 Ph.D.