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Eugene William St. Clair

W. Lester Brooks, Jr. Distinguished Professor of Medicine
Medicine, Rheumatology and Immunology
Duke Box 3874, Durham, NC 27710
34229 Hosp South, Durham, NC 27710

Selected Grants


Pegloticase in Uncontrolled Gout who have undergone Kidney Transplant

Clinical TrialPrincipal Investigator · Awarded by Horizon Therapeutics Ireland DAC · 2019 - 2025

Immunogenicity and risk of autoimmune cross-reactivity of COVID-19 mRNA vaccines in SLE - RRF Investigator Award

ResearchMentor · Awarded by Rheumatology Research Foundation · 2022 - 2025

Subaward Agreement - Benaroya to Duke - ITN Network Deputy Director of Clinical Affairs

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2021 - 2025

CD40L antagonism in RA- ITN FY23ITN566

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2022 - 2024

Pegloticase in Uncontrolled Gout who have undergone Kidney Transplant

Clinical TrialPrincipal Investigator · Awarded by Horizon Therapeutics Ireland DAC · 2019 - 2025

Immunogenicity and risk of autoimmune cross-reactivity of COVID-19 mRNA vaccines in SLE - RRF Investigator Award

ResearchMentor · Awarded by Rheumatology Research Foundation · 2022 - 2025

Subaward Agreement - Benaroya to Duke - ITN Network Deputy Director of Clinical Affairs

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2021 - 2025

CD40L antagonism in RA- ITN FY23ITN566

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2022 - 2024

Subaward Agreement - BRI Immune Tolerance Network FY23TN355 - Protocol Chair - Year 5

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2019 - 2024

Subaward Agreement - Benaroya to Duke - ITN Network Deputy Director of Clinical Affairs

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2020 - 2021

Immunological biomarker studies in myasthenia gravis

Clinical TrialAdvisor · Awarded by National Institutes of Health · 2014 - 2020

Subaward Agreement - Benaroya to Duke - Immune Tolerance Network

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2011 - 2020

BMS-IM101-603

Clinical TrialPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2017 - 2019

Training Program in Inflammatory and Immunological Diseases

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1980 - 2017

Supplement from NIAID for Remaining ACE Invoices

Clinical TrialPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2013 - 2017

Mechanisms of B Cell Responses in Autoimmune Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2003 - 2017

Mechanisms of Insulin Resistance in Rheumatoid Arthritis

ResearchCo-Mentor · Awarded by National Institutes of Health · 2008 - 2015

Scleroderma Cyclophosphamide or Transplantation (SCOT) Trial-Option 2

ResearchAdvisor · Awarded by National Institutes of Health · 2012 - 2013

Mechanisms of Insulin Resistance in Rheumatoid Arthritis

ResearchCo-Mentor · Awarded by National Institutes of Health · 2008 - 2013

Scleroderma Cyclophosphamide or Transplantation (SCOT) Trial

ResearchAdvisor · Awarded by National Institutes of Health · 2011 - 2012

National Collaborative Study of Stem Cell Transplantation for Autoimmune Disease

ResearchAdvisor · Awarded by National Institutes of Health · 2011 - 2011

Abatacept Vs TNF Blockade in Early Rheumatoid Arthritis: Planning for a Randomized, Double-Blind, Placebo-Controlled Trial

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2007 - 2009

Human TNFa-Induced Pre-B Cell Bone Marrow Emigrants

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2006 - 2009

Mentored Clinical Research Scholar Program

ResearchAdvisor · Awarded by National Institutes of Health · 2002 - 2006

General Clinical Research Center

ResearchCore Lab Dir · Awarded by National Institutes of Health · 1998 - 2006

Novel Therapeutic Targets in Rheumatoid Arthritis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1999 - 2004

same

ResearchAdministrative Assistant · Awarded by National Institutes of Health · 1987 - 2001

The Carolina Lupus Research Study

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Specialized Center Of Research In Rheumatoid Arthritis

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1987 - 1999

General Clinical Research Center (Cru)

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1975 - 1998

Intravenous Doxycycline For Rheumatoid Arthritis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1998

Specialized Center Of Research In Rheumatoid Arthritis

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1987 - 1997

External Relationships


  • Everest Clinical Research Corporation
  • Horizon Therapeutics (purchased Viela Bio) and acquired by Amgen
  • Medpace, Inc.
  • Moderna Therapeutics, Inc.
  • Related Sciences
  • Everest Clinical Research Corporation
  • Horizon Therapeutics (purchased Viela Bio) and acquired by Amgen
  • Medpace, Inc.
  • Moderna Therapeutics, Inc.
  • Related Sciences
  • Sonoma Biotherapeutics
  • UpToDate, Inc

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.