Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Medical Oncology Fellowship, Johns Hopkins University School of Medicine 2009 - 2012
  • Internal Medicine Internship and Residency, Johns Hopkins University School of Medicine 2006 - 2009
• 

  Duke Appointment History

  • Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2013 - 2018
  • Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2012 - 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Gaillard, S, Maxwell, GL, Sood, AK, and Berchuck, A. "Biology and genetics." In Berek and Hacker's Gynecologic Oncology: Sixth Edition, 2-38. November 11, 2014.

  • Journal Articles

    • Fader, AN, Bergstrom, J, Jernigan, A, Tanner, EJ, Roche, KL, Stone, RL, Levinson, KL, Ricci, S, Wethingon, S, Wang, T-L, Shih, I-M, Yang, B, Zhang, G, Armstrong, DK, Gaillard, S, Michener, C, DeBernardo, R, and Rose, PG. "Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival?." Gynecologic oncology 147, no. 1 (October 2017): 85-91.  Full Text
    • Chan, JK, Deng, W, Higgins, RV, Tewari, KS, Bonebrake, AJ, Hicks, M, Gaillard, S, Ramirez, PT, Chafe, W, Monk, BJ, and Aghajanian, C. "A phase II evaluation of brivanib in the treatment of persistent or recurrent carcinoma of the cervix: An NRG Oncology/Gynecologic Oncology Group study." Gynecologic oncology 146, no. 3 (September 2017): 554-559.  Full Text
    • Hong, JC, Foote, J, Broadwater, G, Gaillard, S, Havrilesky, LJ, and Chino, JP. "Impact of Chemotherapy and Radiotherapy on Management of Early Stage Clear Cell and Papillary Serous Carcinoma of the Uterus." International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 27, no. 4 (May 2017): 720-729.  Full Text
    • Gaillard, SL, Secord, AA, and Monk, B. "The role of immune checkpoint inhibition in the treatment of ovarian cancer." Gynecologic oncology research and practice 3 (January 2016): 11-. (Review)  Full Text
    • Yu, Y, Gaillard, S, Phillip, JM, Huang, T-C, Pinto, SM, Tessarollo, NG, Zhang, Z, Pandey, A, Wirtz, D, Ayhan, A, Davidson, B, Wang, T-L, and Shih, I-M. "Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules." Cancer cell 28, no. 1 (July 2015): 82-96.  Full Text
    • Havrilesky, LJ, Alvarez Secord, A, Ehrisman, JA, Berchuck, A, Valea, FA, Lee, PS, Gaillard, SL, Samsa, GP, Cella, D, Weinfurt, KP, Abernethy, AP, and Reed, SD. "Patient preferences in advanced or recurrent ovarian cancer." Cancer 120, no. 23 (December 2014): 3651-3659.  Full Text
    • Martin, LP, Sill, M, Shahin, MS, Powell, M, DiSilvestro, P, Landrum, LM, Gaillard, SL, Goodheart, MJ, Hoffman, J, and Schilder, RJ. "A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a Gynecologic Oncology Group study." Gynecol Oncol 132, no. 3 (March 2014): 526-530.  Full Text  Link to Item
    • Havrilesky, LJ, Secord, AA, Ehrisman, JA, Berchuck, A, Valea, FA, Lee, PS, Gaillard, SL, Samsa, GP, Cella, D, Weinfurt, KP, Abernethy, AP, and Reed, SD. "Patient preferences in advanced or recurrent ovarian cancer." Cancer 120, no. 23 (January 1, 2014): 3651-3659.  Full Text
    • Martin, LP, Sill, M, Shahin, MS, Powell, M, Disilvestro, P, Landrum, LM, Gaillard, SL, Goodheart, MJ, Hoffman, J, and Schilder, RJ. "A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: A Gynecologic Oncology Group study." Gynecologic Oncology 132, no. 3 (January 1, 2014): 526-530.  Full Text
    • Gaillard, S, Dinoso, JB, Marsh, JA, DeZern, AE, O'Connell, KA, Spivak, AM, Alwood, K, Durand, CM, Ambinder, RF, and Blankson, JN. "Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy." Journal of Clinical Virology 51, no. 3 (2011): 195-198.  Full Text
    • Gaillard, S, and Armstrong, D. "Intraperitoneal chemotherapy for advanced epithelial ovarian cancer: Many questions, much promise&amp." Oncology 25, no. 2 (2011).
    • Gaillard, S, and Stearns, V. "Aromatase inhibitor-associated bone and musculoskeletal effects: New evidence defining etiology and strategies for management." Breast Cancer Research 13, no. 2 (2011).  Full Text
    • Grasfeder, LL, Gaillard, S, Hammes, SR, Ilkayeva, O, Newgard, CB, Hochberg, RB, Dwyer, MA, Chang, C-Y, and McDonnell, DP. "Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha." Mol Endocrinol 23, no. 8 (August 2009): 1171-1182.  Full Text  Link to Item
    • Stein, RA, Gaillard, S, and McDonnell, DP. "Estrogen-related receptor alpha induces the expression of vascular endothelial growth factor in breast cancer cells." J Steroid Biochem Mol Biol 114, no. 1-2 (March 2009): 106-112.  Full Text  Link to Item
    • Gaillard, S, and Wondisford, FE. "Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor." Clinical Management of Thyroid Disease (2009): 81-101.  Full Text
    • Gaillard, S, Dwyer, MA, and McDonnell, DP. "Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions." Mol Endocrinol 21, no. 1 (January 2007): 62-76.  Full Text  Link to Item
    • Gaillard, S, Grasfeder, LL, Haeffele, CL, Lobenhofer, EK, Chu, T-M, Wolfinger, R, Kazmin, D, Koves, TR, Muoio, DM, Chang, C-Y, and McDonnell, DP. "Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs." Mol Cell 24, no. 5 (December 8, 2006): 797-803.  Full Text  Link to Item
    • Chao, EYH, Collins, JL, Gaillard, S, Miller, AB, Wang, L, Orband-Miller, LA, Nolte, RT, McDonnell, DP, Willson, TM, and Zuercher, WJ. "Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRγ." Bioorganic and Medicinal Chemistry Letters 16, no. 4 (2006): 821-824.  Full Text
    • Zhang, Y, Ma, K, Sadana, P, Chowdhury, F, Gaillard, S, Wang, F, McDonnell, DP, Unterman, TG, Elam, MB, and Park, EA. "Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression." Journal of Biological Chemistry 281, no. 52 (2006): 39897-39906.  Full Text
    • Safi, R, Kovacic, A, Gaillard, S, Murata, Y, Simpson, ER, McDonnell, DP, and Clyne, CD. "Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy." Cancer Res 65, no. 24 (December 15, 2005): 11762-11770.  Full Text  Link to Item
    • Kovacs, JJ, Murphy, PJM, Gaillard, S, Zhao, X, Wu, J-T, Nicchitta, CV, Yoshida, M, Toft, DO, Pratt, WB, and Yao, T-P. "HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor." Mol Cell 18, no. 5 (May 27, 2005): 601-607.  Full Text  Link to Item
    • Zuercher, WJ, Gaillard, S, Orband-Miller, LA, Chao, EYH, Shearer, BG, Jones, DG, Miller, AB, Collins, JL, McDonnell, DP, and Willson, TM. "Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRβ and ERRγ." Journal of Medicinal Chemistry 48, no. 9 (2005): 3107-3109.  Full Text

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