Overview
I am an Adult and Pediatric Rheumatologist and care for patients with a wide variety of autoimmune and rheumatic diseases, including: systemic lupus, rheumatoid arthritis, juvenile arthritis, vasculitis, and sarcoidosis, among others. I have a special interest in using musculoskeletal ultrasound to optimize diagnosis and treatment decisions at the bedside.
I am also a clinical researcher at the Duke Clinical Research Institute (DCRI). My research interests are in clinical trials and precision medicine through population pharmacokinetic/pharmacodynamic modeling. I obtained my PhD in Pharmaceutical Sciences from the UNC Eshelman School of Pharmacy. I serve as the principal investigator on several grants studying hydroxychloroquine and azathioprine pharmacokinetics and exposure-response in lupus, as well as principal investigator or co-investigator for several clinical trials at the DCRI. Additionally, I am an Assistant Scientific Director for the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry- the largest registry of children with rheumatic diseases in North America.
I am also a clinical researcher at the Duke Clinical Research Institute (DCRI). My research interests are in clinical trials and precision medicine through population pharmacokinetic/pharmacodynamic modeling. I obtained my PhD in Pharmaceutical Sciences from the UNC Eshelman School of Pharmacy. I serve as the principal investigator on several grants studying hydroxychloroquine and azathioprine pharmacokinetics and exposure-response in lupus, as well as principal investigator or co-investigator for several clinical trials at the DCRI. Additionally, I am an Assistant Scientific Director for the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry- the largest registry of children with rheumatic diseases in North America.
Current Appointments & Affiliations
Associate Professor of Pediatrics
·
2022 - Present
Pediatrics, Rheumatology,
Pediatrics
Associate Professor of Medicine
·
2022 - Present
Medicine, Rheumatology and Immunology,
Medicine
Member in the Duke Clinical Research Institute
·
2018 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Correction: Population Pharmacokinetic Modeling of Oxcarbazepine and Its Active Metabolite 10‑Monohydroxy Derivative to Inform Dosing in Children with Obesity.
Journal Article Clin Pharmacokinet · January 6, 2026 Full text Link to item CiteDosing Biologic Drugs for Patients with Obesity: One Size Does NOT Fit All.
Journal Article Arthritis Rheumatol · November 27, 2025 Full text Link to item CitePopulation Pharmacokinetic Modeling of Oxcarbazepine and Its Active Metabolite 10-Monohydroxy Derivative to Inform Dosing in Children with Obesity.
Journal Article Clin Pharmacokinet · November 17, 2025 BACKGROUND: Oxcarbazepine (OXZ) is an antiepileptic drug whose pharmacological effect is primarily mediated by its active metabolite, 10-monohydroxy derivative (MHD). OXZ is approved for use in adults and children older than 2 years with an age- and body w ... Full text Link to item CiteRecent Grants
PTN 3.0 Task Order #2_ BPCA Pediatric Drug Development Clinical Trial Infrastructure
ResearchProject Leader · Awarded by National Institutes of Health · 2025 - 2030Induced Suppression of Platelet Activity in Aneurysmal SAH Management-2 (iSPASM-2)
Clinical TrialInvestigator · Awarded by National Institutes of Health · 2025 - 2030Pharmacokinetic Modeling to Optimize Dosing in Pediatric Rheumatic Diseases
ResearchPrincipal Investigator · Awarded by Thrasher Research Fund · 2025 - 2028View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2022
Ph.D.
Duke University, School of Medicine ·
2018
M.H.S.
Marshall University ·
2010
M.D.