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Stephen Joseph Balevic

Associate Professor of Pediatrics
Pediatrics, Rheumatology
2301 Erwin Rd, Durham, NC 27710
2301 Erwin Rd, Durham, NC 27710

Overview


I am an Adult and Pediatric Rheumatologist and care for patients with a wide variety of autoimmune and rheumatic diseases, including: systemic lupus, rheumatoid arthritis, juvenile arthritis, vasculitis, and sarcoidosis, among others. I have a special interest in using musculoskeletal ultrasound to optimize diagnosis and treatment decisions at the bedside.

I am also a clinical researcher at the Duke Clinical Research Institute (DCRI). My research interests are in clinical trials and precision medicine through population pharmacokinetic/pharmacodynamic modeling. I obtained my PhD in Pharmaceutical Sciences from the UNC Eshelman School of Pharmacy. I serve as the principal investigator on several grants studying hydroxychloroquine and azathioprine pharmacokinetics and exposure-response in lupus, as well as principal investigator or co-investigator for several clinical trials at the DCRI. Additionally, I am an Assistant Scientific Director for the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry- the largest registry of children with rheumatic diseases in North America.

Current Duke Appointments & Affiliations


Associate Professor of Pediatrics · 2022 - Present Pediatrics, Rheumatology, Pediatrics
Associate Professor of Medicine · 2022 - Present Medicine, Rheumatology and Immunology, Medicine
Member in the Duke Clinical Research Institute · 2018 - Present Duke Clinical Research Institute, Institutes and Centers

Recent News Items


Published September 22, 2020
DCRI Pulse
DCRI Launches First Direct-to-Family Study

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Recent Scholarly Works


Population Pharmacokinetics and Dosing Simulations of Pentobarbital in the Pediatric Population.

Journal article J Clin Pharmacol · May 2026 Pentobarbital is a barbiturate with sedative and anticonvulsant properties, occasionally used in pediatric patients for preoperative sedation, deep sedation during mechanical ventilation, and seizure control. Despite its long-standing clinical use, age-app ... Full text Link to item Cite

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study.

Journal article Arthritis Care Res (Hoboken) · April 3, 2026 OBJECTIVE: Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecolo ... Full text Link to item Cite
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Recent Grants


INNOVATE (Integrated National Network for Obstetric and Pediatric AdVAncement in Therapeutic Education)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2026 - 2031

Azathioprine Safety and Pharmacokinetics in Pregnant Women with Rheumatic Disease and their Infants

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2031

PTN 3.0 Task Order #2_ BPCA Pediatric Drug Development Clinical Trial Infrastructure

ResearchProject Leader · Awarded by National Institutes of Health · 2025 - 2030

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Education


University of North Carolina, Chapel Hill · 2022 Ph.D.
Duke University, School of Medicine · 2018 M.H.S.
Marshall University · 2010 M.D.