Scholars@Duke
M. Stephen Melton

M. Stephen Melton

Associate Professor of Anesthesiology
Anesthesiology, Ambulatory
steve.melton@duke.edu
Box # 3094, Stop # 4, Durham, NC 27710
Box # 3094, Stop # 4, Durham, NC 27710

Selected Publications

Admixture of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Peripheral Nerve Blocks in Adolescents Undergoing Orthopedic Surgery: An Observational Cohort Study.

Journal Article J Clin Med · December 13, 2024 Background/Objectives: In 2021, the Food and Drug Administration approved liposomal bupivacaine injectable suspension for single-dose infiltration in patients ≥ 6 years of age. Liposomal bupivacaine and bupivacaine hydrochloride admixtures may also be admi ... Full text Link to item Cite

Rupture, reconstruction, and rehabilitation: A multi-disciplinary review of mechanisms for central nervous system adaptations following anterior cruciate ligament injury.

Journal Article Knee · June 2021 BACKGROUND: Despite surgical reconstruction and extensive rehabilitation, persistent quadriceps inhibition, gait asymmetry, and functional impairment remain prevalent in patients after anterior cruciate ligament (ACL) injury. A combination of reports have ... Full text Link to item Cite

Unplanned hospital admission after ambulatory surgery: a retrospective, single cohort study.

Journal Article Can J Anaesth · January 2021 PURPOSE: We estimated the rate of unplanned hospital and intensive care unit (ICU) admissions following ambulatory surgery centre (ASC) procedures, and identified factors associated with their occurrence. METHODS: This retrospective cohort included adult p ... Full text Link to item Cite

Neural activation for actual and imagined movement following unilateral hand transplantation: a case study.

Journal Article Neurocase · December 2019 Transplantation of a donor hand has been successful as a surgical treatment following amputation, but little is known regarding the brain mechanisms contributing to the recovery of motor function. We report functional magnetic resonance imaging (fMRI) find ... Full text Open Access Link to item Cite

Regional Anesthesia for Ambulatory Anesthesiologists.

Journal Article Anesthesiol Clin · June 2019 Proper pain control is critical for ambulatory surgery. Regional anesthesia can decrease postoperative pain, improve patient satisfaction, and expedite patient discharge. This article discusses the techniques, clinical pearls, and potential pitfalls associ ... Full text Link to item Cite

Acute Pain Medicine

Book · May 14, 2019 Written and edited under the auspices of the American Academy of Pain Medicine by members of the Academy's Shared Interest Group for Acute Pain Medicine, the text includes an introduction to acute pain medicine and an easily referenced ... ... Cite

Anesthesiology

Chapter · January 1, 2018 Cite

Effect of Interscalene Brachial Plexus Block on the Pulmonary Function of Obese Patients: A Prospective, Observational Cohort Study.

Journal Article Anesth Analg · July 2017 BACKGROUND: The effect of interscalene block (ISB) on pulmonary function of obese participants has not been investigated. The goal of this study is to assess the association of obesity (body mass index [BMI] >29 kg/m vs BMI <25 kg/m) and change in forced v ... Full text Link to item Cite

Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study.

Journal Article Anesthesiology · August 2016 BACKGROUND: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity (RSFC) is being used to study br ... Full text Open Access Link to item Cite

Long-acting serotonin antagonist (Palonosetron) and the NK-1 receptor antagonists: does extended duration of action improve efficacy?

Journal Article Anesthesiol Clin · June 2014 In a growing outpatient surgical population, postdischarge nausea and vomiting (PDNV) is unfortunately a common and costly anesthetic complication. Identification of risk factors for both postoperative nausea and vomiting and PDNV is the hallmark of preven ... Full text Link to item Cite

New medications and techniques in ambulatory anesthesia.

Journal Article Anesthesiol Clin · June 2014 Novel anesthetic and analgesic agents are currently under development or investigation to improve anesthetic delivery and patient care. The pharmacokinetic and analgesic profiles of these agents are especially tailored to meet the challenges of rapid recov ... Full text Link to item Cite

Peripheral nerve stimulation in regional anesthesia.

Journal Article Reg Anesth Pain Med · 2012 Peripheral nerve stimulation has a long history in regional anesthesia. Despite the advent of ultrasound-guided peripheral nerve blockade, nerve stimulation remains a popular technique used alone or, now, in combination with ultrasound-guided techniques. I ... Full text Link to item Cite

Management of postdischarge nausea and vomiting after ambulatory surgery.

Journal Article Curr Opin Anaesthesiol · December 2011 PURPOSE OF REVIEW: Although there are extensive studies of postoperative and postdischarge nausea and vomiting (PONV/PDNV) up to 24  h, few investigate 'delayed PDNV'. With an increasing outpatient surgical population, specific 'delayed PDNV' risk identifi ... Full text Link to item Cite

Contralateral local anesthetic spread from an outpatient interscalene catheter.

Journal Article Can J Anaesth · October 2010 PURPOSE: Ambulatory continuous infusions have been associated with improved analgesia and few serious complications. This report describes an unusual case of a patient with a continuous interscalene nerve block who developed a contralateral upper extremity ... Full text Link to item Cite