Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of London (United Kingdom) 1969
• 

  Duke Appointment History

  • Assistant Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2010 - 2017
• Research
• 

  Selected Grants

  • Metabolic Regulators of Insulin Secretion and Insulin Resistance awarded by National Institutes of Health 2013 - 2015
  • NCI Metabolomics Assays awarded by National Institutes of Health 2007 - 2009
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Kadakia, Rachel, Octavious Talbot, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Cord Blood Metabolomics: Association With Newborn Anthropometrics and C-Peptide Across Ancestries.” J Clin Endocrinol Metab 104, no. 10 (October 1, 2019): 4459–72. https://doi.org/10.1210/jc.2019-00238.
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    • Younge, Noelle E., Christopher B. Newgard, C Michael Cotten, Ronald N. Goldberg, Michael J. Muehlbauer, James R. Bain, Robert D. Stevens, et al. “Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure.” Sci Rep 9, no. 1 (June 3, 2019): 8167. https://doi.org/10.1038/s41598-019-44547-y.
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    • Kadakia, Rachel, Michael Nodzenski, Octavious Talbot, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, et al. “Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries.” Diabetologia 62, no. 3 (March 2019): 473–84. https://doi.org/10.1007/s00125-018-4781-1.
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    • Fisher-Wellman, Kelsey H., James A. Draper, Michael T. Davidson, Ashley S. Williams, Tara M. Narowski, Dorothy H. Slentz, Olga R. Ilkayeva, et al. “Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.” Cell Rep 26, no. 6 (February 5, 2019): 1557-1572.e8. https://doi.org/10.1016/j.celrep.2019.01.057.
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    • Ravi, Saranya, Traci L. Parry, Monte S. Willis, Pamela Lockyer, Cam Patterson, James R. Bain, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, and Jonathan C. Schisler. “Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP.” J Cardiovasc Dev Dis 5, no. 3 (August 15, 2018). https://doi.org/10.3390/jcdd5030043.
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    • An, Jie, Liping Wang, Michael L. Patnode, Vanessa K. Ridaura, Jonathan M. Haldeman, Robert D. Stevens, Olga Ilkayeva, et al. “Physiological mechanisms of sustained fumagillin-induced weight loss.” Jci Insight 3, no. 5 (March 8, 2018). https://doi.org/10.1172/jci.insight.99453.
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    • Jacob, Saya, Michael Nodzenski, Anna C. Reisetter, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.” Diabetes Care 40, no. 7 (July 2017): 911–19. https://doi.org/10.2337/dc16-2453.
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    • Lowe, William L., James R. Bain, Michael Nodzenski, Anna C. Reisetter, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Maternal BMI and Glycemia Impact the Fetal Metabolome.” Diabetes Care 40, no. 7 (July 2017): 902–10. https://doi.org/10.2337/dc16-2452.
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    • Anderson, Kristin A., Frank K. Huynh, Kelsey Fisher-Wellman, J Darren Stuart, Brett S. Peterson, Jonathan D. Douros, Gregory R. Wagner, et al. “SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.” Cell Metab 25, no. 4 (April 4, 2017): 838-855.e15. https://doi.org/10.1016/j.cmet.2017.03.003.
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    • Wagner, Gregory R., Dhaval P. Bhatt, Thomas M. O’Connell, J Will Thompson, Laura G. Dubois, Donald S. Backos, Hao Yang, et al. “A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.” Cell Metab 25, no. 4 (April 4, 2017): 823-837.e8. https://doi.org/10.1016/j.cmet.2017.03.006.
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    • Sandler, Victoria, Anna C. Reisetter, James R. Bain, Michael J. Muehlbauer, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, et al. “Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.” Diabetologia 60, no. 3 (March 2017): 518–30. https://doi.org/10.1007/s00125-016-4182-2.
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    • Reisetter, Anna C., Michael J. Muehlbauer, James R. Bain, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, Boyd E. Metzger, Christopher B. Newgard, William L. Lowe, and Denise M. Scholtens. “Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.” Bmc Bioinformatics 18, no. 1 (February 2, 2017): 84. https://doi.org/10.1186/s12859-017-1501-7.
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    • Kraus, William E., Carl F. Pieper, Kim M. Huffman, Dana K. Thompson, Virginia B. Kraus, Miriam C. Morey, Harvey J. Cohen, et al. “Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.” J Gerontol a Biol Sci Med Sci 71, no. 11 (November 2016): 1507–13. https://doi.org/10.1093/gerona/glw031.
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    • Hunter, Wynn G., Jacob P. Kelly, Robert W. McGarrah, Michel G. Khouri, Damian Craig, Carol Haynes, Olga Ilkayeva, et al. “Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure.” J Am Heart Assoc 5, no. 8 (July 29, 2016). https://doi.org/10.1161/JAHA.115.003190.
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    • Scholtens, Denise M., James R. Bain, Anna C. Reisetter, Michael J. Muehlbauer, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, et al. “Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.” Diabetes 65, no. 7 (July 2016): 2039–50. https://doi.org/10.2337/db15-1748.
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    • White, Phillip J., Amanda L. Lapworth, Jie An, Liping Wang, Robert W. McGarrah, Robert D. Stevens, Olga Ilkayeva, et al. “Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.” Mol Metab 5, no. 7 (July 2016): 538–51. https://doi.org/10.1016/j.molmet.2016.04.006.
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    • Marcelo, Kathrina L., Thomas Ribar, Christopher R. Means, Anna Tsimelzon, Robert D. Stevens, Olga Ilkayeva, James R. Bain, et al. “Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism.” Mol Endocrinol 30, no. 5 (May 2016): 557–72. https://doi.org/10.1210/me.2016-1021.
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    • Davies, Michael N., Lilja Kjalarsdottir, J Will Thompson, Laura G. Dubois, Robert D. Stevens, Olga R. Ilkayeva, M Julia Brosnan, Timothy P. Rolph, Paul A. Grimsrud, and Deborah M. Muoio. “The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins.” Cell Rep 14, no. 2 (January 12, 2016): 243–54. https://doi.org/10.1016/j.celrep.2015.12.030.
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    • Glynn, Erin L., Lucy W. Piner, Kim M. Huffman, Cris A. Slentz, Lorraine Elliot-Penry, Hiba AbouAssi, Phillip J. White, et al. “Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.” Diabetologia 58, no. 10 (October 2015): 2324–35. https://doi.org/10.1007/s00125-015-3705-6.
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    • Keenan, Melissa M., Beiyu Liu, Xiaohu Tang, Jianli Wu, Derek Cyr, Robert D. Stevens, Olga Ilkayeva, et al. “ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.” Plos Genet 11, no. 10 (October 2015): e1005599. https://doi.org/10.1371/journal.pgen.1005599.
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    • Kien, C Lawrence, Dwight E. Matthews, Matthew E. Poynter, Janice Y. Bunn, Naomi K. Fukagawa, Karen I. Crain, David B. Ebenstein, et al. “Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation.” J Lipid Res 56, no. 9 (September 2015): 1795–1807. https://doi.org/10.1194/jlr.M060137.
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    • Seiler, Sarah E., Timothy R. Koves, Jessica R. Gooding, Kari E. Wong, Robert D. Stevens, Olga R. Ilkayeva, April H. Wittmann, et al. “Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise.” Cell Metab 22, no. 1 (July 7, 2015): 65–76. https://doi.org/10.1016/j.cmet.2015.06.003.
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    • Wong, Kari E., Catherine R. Mikus, Dorothy H. Slentz, Sarah E. Seiler, Karen L. DeBalsi, Olga R. Ilkayeva, Karen I. Crain, et al. “Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction.” Diabetes 64, no. 5 (May 2015): 1532–43. https://doi.org/10.2337/db14-0827.
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    • Glass, O. K., B. A. Inman, G. Broadwater, K. S. Courneya, J. R. Mackey, S. Goruk, E. R. Nelson, et al. “Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study.” Br J Cancer 112, no. 5 (March 3, 2015): 825–31. https://doi.org/10.1038/bjc.2014.662.
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    • Palmer, Nicholette D., Robert D. Stevens, Peter A. Antinozzi, Andrea Anderson, Richard N. Bergman, Lynne E. Wagenknecht, Christopher B. Newgard, and Donald W. Bowden. “Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study.” J Clin Endocrinol Metab 100, no. 3 (March 2015): E463–68. https://doi.org/10.1210/jc.2014-2357.
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    • Glass, O. K., B. A. Inman, G. Broadwater, K. S. Courneya, J. R. Mackey, S. Goruk, E. R. Nelson, et al. “Effect of aerobic training on the host systemic milieu in patients with solid tumours: An exploratory correlative study.” British Journal of Cancer 112, no. 5 (January 1, 2015): 825–31. https://doi.org/10.1038/bjc.2014.662.
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    • Newbern, D., P. Gumus Balikcioglu, M. Balikcioglu, J. Bain, M. Muehlbauer, R. Stevens, O. Ilkayeva, et al. “Erratum: Sex differences in biomarkers associated with insulin resistance in obese adolescents: Metabolomic profiling and principal components analysis (Journal of Clinical Endocrinology and Metabolism (2014) 99 (4730-4739) DOI: 10.1210/jc.2014-2080).” Journal of Clinical Endocrinology and Metabolism 100, no. 4 (January 1, 2015): 1709. https://doi.org/10.1210/jc.2015-1354.
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    • Newbern, Dorothee, Pinar Gumus Balikcioglu, Metin Balikcioglu, James Bain, Michael Muehlbauer, Robert Stevens, Olga Ilkayeva, et al. “Sex differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis.” J Clin Endocrinol Metab 99, no. 12 (December 2014): 4730–39. https://doi.org/10.1210/jc.2014-2080.
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    • Huffman, Kim M., Timothy R. Koves, Monica J. Hubal, Hiba Abouassi, Nina Beri, Lori A. Bateman, Robert D. Stevens, et al. “Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness.” Diabetologia 57, no. 11 (November 2014): 2282–95. https://doi.org/10.1007/s00125-014-3343-4.
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    • Lai, Ling, Teresa C. Leone, Mark P. Keller, Ola J. Martin, Aimee T. Broman, Jessica Nigro, Kapil Kapoor, et al. “Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.” Circ Heart Fail 7, no. 6 (November 2014): 1022–31. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001469.
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    • Lindeboom, Lucas, Christine I. Nabuurs, Joris Hoeks, Bram Brouwers, Esther Phielix, M Eline Kooi, Matthijs K. C. Hesselink, et al. “Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection.” J Clin Invest 124, no. 11 (November 2014): 4915–25. https://doi.org/10.1172/JCI74830.
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    • Tannour-Louet, Mounia, Brian York, Ke Tang, Erin Stashi, Hichem Bouguerra, Suoling Zhou, Hui Yu, et al. “Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis.” Mol Endocrinol 28, no. 10 (October 2014): 1707–18. https://doi.org/10.1210/me.2014-1083.
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    • Tripathy, Sasmita, Kelli A. Lytle, Robert D. Stevens, James R. Bain, Christopher B. Newgard, Andrew S. Greenberg, Li-Shin Huang, and Donald B. Jump. “Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.” J Lipid Res 55, no. 7 (July 2014): 1448–64. https://doi.org/10.1194/jlr.M050062.
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    • Bartz, Sarah, Aaloke Mody, Christoph Hornik, James Bain, Michael Muehlbauer, Tonny Kiyimba, Elizabeth Kiboneka, et al. “Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality.” J Clin Endocrinol Metab 99, no. 6 (June 2014): 2128–37. https://doi.org/10.1210/jc.2013-4018.
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    • Gupte, Anisha A., Dale J. Hamilton, Andrea M. Cordero-Reyes, Keith A. Youker, Zheng Yin, Jerry D. Estep, Robert D. Stevens, et al. “Mechanical unloading promotes myocardial energy recovery in human heart failure.” Circ Cardiovasc Genet 7, no. 3 (June 2014): 266–76. https://doi.org/10.1161/CIRCGENETICS.113.000404.
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    • Khoo, Chin Meng, Michael J. Muehlbauer, Robert D. Stevens, Zehra Pamuklar, Jiegen Chen, Christopher B. Newgard, and Alfonso Torquati. “Postprandial metabolite profiles reveal differential nutrient handling after bariatric surgery compared with matched caloric restriction.” Ann Surg 259, no. 4 (April 2014): 687–93. https://doi.org/10.1097/SLA.0b013e318296633f.
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    • DeBalsi, Karen L., Kari E. Wong, Timothy R. Koves, Dorothy H. Slentz, Sarah E. Seiler, April H. Wittmann, Olga R. Ilkayeva, et al. “Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle.” J Biol Chem 289, no. 12 (March 21, 2014): 8106–20. https://doi.org/10.1074/jbc.M113.511535.
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    • Kien, C Lawrence, Janice Y. Bunn, Robert Stevens, James Bain, Olga Ikayeva, Karen Crain, Timothy R. Koves, and Deborah M. Muoio. “Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans.” Am J Clin Nutr 99, no. 3 (March 2014): 436–45. https://doi.org/10.3945/ajcn.113.070557.
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    • Bhattacharya, Sayanti, Christopher B. Granger, Damian Craig, Carol Haynes, James Bain, Robert D. Stevens, Elizabeth R. Hauser, et al. “Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization.” Atherosclerosis 232, no. 1 (January 2014): 191–96. https://doi.org/10.1016/j.atherosclerosis.2013.10.036.
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    • Mody, Aaloke, Sarah Bartz, Christoph P. Hornik, Tonny Kiyimba, James Bain, Michael Muehlbauer, Elizabeth Kiboneka, et al. “Effects of HIV infection on the metabolic and hormonal status of children with severe acute malnutrition.” Plos One 9, no. 7 (2014): e102233. https://doi.org/10.1371/journal.pone.0102233.
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    • Scholtens, Denise M., Michael J. Muehlbauer, Natalie R. Daya, Robert D. Stevens, Alan R. Dyer, Lynn P. Lowe, Boyd E. Metzger, et al. “Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy.” Diabetes Care 37, no. 1 (2014): 158–66. https://doi.org/10.2337/dc13-0989.
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    • Rardin, Matthew J., Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico, Steven R. Danielson, Ailan Guo, et al. “SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.” Cell Metab 18, no. 6 (December 3, 2013): 920–33. https://doi.org/10.1016/j.cmet.2013.11.013.
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    • Patel, Mahesh J., Bryan C. Batch, Laura P. Svetkey, James R. Bain, Christy Boling Turer, Carol Haynes, Michael J. Muehlbauer, Robert D. Stevens, Christopher B. Newgard, and Svati H. Shah. “Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.” Omics 17, no. 12 (December 2013): 627–35. https://doi.org/10.1089/omi.2013.0031.
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    • Batch, Bryan C., Svati H. Shah, Christopher B. Newgard, Christy B. Turer, Carol Haynes, James R. Bain, Michael Muehlbauer, et al. “Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness.” Metabolism 62, no. 7 (July 2013): 961–69. https://doi.org/10.1016/j.metabol.2013.01.007.
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    • Johnson, Erika Segear, Kelly R. Lindblom, Alexander Robeson, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, Sally Kornbluth, and Joshua L. Andersen. “Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis.” J Biol Chem 288, no. 20 (May 17, 2013): 14463–75. https://doi.org/10.1074/jbc.M112.437210.
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    • Kien, C Lawrence, Janice Y. Bunn, Matthew E. Poynter, Robert Stevens, James Bain, Olga Ikayeva, Naomi K. Fukagawa, et al. “A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults.” Diabetes 62, no. 4 (April 2013): 1054–63. https://doi.org/10.2337/db12-0363.
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    • Patel, Sanjeet G., Jean W. Hsu, Farook Jahoor, Ivonne Coraza, James R. Bain, Robert D. Stevens, Dinakar Iyer, et al. “Pathogenesis of A⁻β⁺ ketosis-prone diabetes.” Diabetes 62, no. 3 (March 2013): 912–22. https://doi.org/10.2337/db12-0624.
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    • Coppola, Anna, Brett R. Wenner, Olga Ilkayeva, Robert D. Stevens, Mauro Maggioni, Theodore A. Slotkin, Edward D. Levin, and Christopher B. Newgard. “Branched-chain amino acids alter neurobehavioral function in rats.” Am J Physiol Endocrinol Metab 304, no. 4 (February 15, 2013): E405–13. https://doi.org/10.1152/ajpendo.00373.2012.
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    • York, Brian, Jørn V. Sagen, Anna Tsimelzon, Jean-Francios Louet, Atul R. Chopra, Erin L. Reineke, Suoling Zhou, et al. “Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family.” Mol Endocrinol 27, no. 2 (February 2013): 366–80. https://doi.org/10.1210/me.2012-1324.
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    • Shimazu, Tadahiro, Matthew D. Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A. Grueter, et al. “Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.” Science 339, no. 6116 (January 11, 2013): 211–14. https://doi.org/10.1126/science.1227166.
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    • Gregory, Jesse F., Youngja Park, Yvonne Lamers, Nirmalya Bandyopadhyay, Yueh-Yun Chi, Kichen Lee, Steven Kim, et al. “Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects.” Plos One 8, no. 6 (2013): e63544. https://doi.org/10.1371/journal.pone.0063544.
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    • Chao, Lily C., Kevin Wroblewski, Olga R. Ilkayeva, Robert D. Stevens, James Bain, Gretchen A. Meyer, Simon Schenk, et al. “Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.” J Lipid Res 53, no. 12 (December 2012): 2610–19. https://doi.org/10.1194/jlr.M029355.
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    • Gupte, Anisha, Dale J. Hamilton, Andrea M. Cordero-Reyes, Keith A. Youker, Matthias Loebe, Robert D. Stevens, Brett Wenner, et al. “Metabolomic and Gene Expression Changes in End-Stage Heart Failure are Reversed by Left Ventricular Assist Device.” Circulation 126, no. 21 (November 20, 2012).
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    • Gaudet, Mia M., Roni T. Falk, Robert D. Stevens, Marc J. Gunter, James R. Bain, Ruth M. Pfeiffer, Nancy Potischman, et al. “Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study.” J Clin Endocrinol Metab 97, no. 9 (September 2012): 3216–23. https://doi.org/10.1210/jc.2012-1490.
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    • Kim, Dong-Hoon, Maureen A. Sartor, James R. Bain, Darleen Sandoval, Robert D. Stevens, Mario Medvedovic, Christopher B. Newgard, Stephen C. Woods, and Randy J. Seeley. “Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.” Diabetes 61, no. 9 (September 2012): 2299–2310. https://doi.org/10.2337/db11-1579.
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    • Thompson, Dana K., Richard Sloane, James R. Bain, Robert D. Stevens, Christopher B. Newgard, Carl F. Pieper, and Virginia B. Kraus. “Daily Variation of Serum Acylcarnitines and Amino Acids.” Metabolomics 8, no. 4 (August 2012): 556–65. https://doi.org/10.1007/s11306-011-0345-9.
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    • Sinha, Rohit Anthony, Seo-Hee You, Jin Zhou, Mobin M. Siddique, Boon-Huat Bay, Xuguang Zhu, Martin L. Privalsky, et al. “Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.” J Clin Invest 122, no. 7 (July 2012): 2428–38. https://doi.org/10.1172/JCI60580.
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    • Muoio, Deborah M., Robert C. Noland, Jean-Paul Kovalik, Sarah E. Seiler, Michael N. Davies, Karen L. DeBalsi, Olga R. Ilkayeva, et al. “Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.” Cell Metab 15, no. 5 (May 2, 2012): 764–77. https://doi.org/10.1016/j.cmet.2012.04.005.
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    • York, Brian, Erin L. Reineke, Jørn V. Sagen, Bryan C. Nikolai, Suoling Zhou, Jean-Francois Louet, Atul R. Chopra, et al. “Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.” Cell Metab 15, no. 5 (May 2, 2012): 752–63. https://doi.org/10.1016/j.cmet.2012.03.020.
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    • Shah, Svati H., Jie-Lena Sun, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Karen S. Pieper, Carol Haynes, et al. “Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease.” Am Heart J 163, no. 5 (May 2012): 844-850.e1. https://doi.org/10.1016/j.ahj.2012.02.005.
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    • Glynn, Erin L., Jie An, Li-Ping Wang, Olga R. Ilkayeva, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, et al. “Caloric restriction, aerobic exercise or a combination improves metabolic profiles following diet-induced obesity.” Faseb Journal 26 (April 1, 2012).
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    • Shah, Asad A., Damian M. Craig, Jacqueline K. Sebek, Carol Haynes, Robert C. Stevens, Michael J. Muehlbauer, Christopher B. Granger, et al. “Metabolic profiles predict adverse events after coronary artery bypass grafting.” J Thorac Cardiovasc Surg 143, no. 4 (April 2012): 873–78. https://doi.org/10.1016/j.jtcvs.2011.09.070.
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    • Anderson, Kristin A., Fumin Lin, Thomas J. Ribar, Robert D. Stevens, Michael J. Muehlbauer, Christopher B. Newgard, and Anthony R. Means. “Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse.” Mol Endocrinol 26, no. 2 (February 2012): 281–91. https://doi.org/10.1210/me.2011-1299.
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    • Shah, S. H., D. R. Crosslin, C. S. Haynes, S. Nelson, C. B. Turer, R. D. Stevens, M. J. Muehlbauer, et al. “Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss.” Diabetologia 55, no. 2 (February 2012): 321–30. https://doi.org/10.1007/s00125-011-2356-5.
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    • Huffman, Kim M., Leanne M. Redman, Lawrence R. Landerman, Carl F. Pieper, Robert D. Stevens, Michael J. Muehlbauer, Brett R. Wenner, et al. “Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.” Plos One 7, no. 4 (2012): e28190. https://doi.org/10.1371/journal.pone.0028190.
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    • Ku, Bon Jeong, Tae Hoon Kim, Jae Hee Lee, Eric D. Buras, Lisa D. White, Robert D. Stevens, Olga R. Ilkayeva, et al. “Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.” Plos One 7, no. 8 (2012): e42915. https://doi.org/10.1371/journal.pone.0042915.
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    • Sampey, Brante P., Alex J. Freemerman, Jimmy Zhang, Pei-Fen Kuan, Joseph A. Galanko, Thomas M. O’Connell, Olga R. Ilkayeva, et al. “Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation.” Plos One 7, no. 6 (2012): e38812. https://doi.org/10.1371/journal.pone.0038812.
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    • Brunner, Michael P., Svati H. Shah, Damian M. Craig, Robert D. Stevens, Michael J. Muehlbauer, James R. Bain, Christopher B. Newgard, et al. “Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization.” Circ Cardiovasc Genet 4, no. 6 (December 2011): 695–700. https://doi.org/10.1161/CIRCGENETICS.111.960575.
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    • Bhattacharya, Sayanti, Damian Craig, Carol Haynes, Christopher B. Granger, Robert D. Stevens, Elizabeth R. Hauser, William E. Kraus, Christopher B. Newgard, L. K. Newby, and Svati H. Shah. “Peripheral Metabolite Profiles Discriminate Coronary Artery Disease in a Sequential Cohort of Cardiac Catheterization Patients.” Circulation 124, no. 21 (November 22, 2011).
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    • Hirschey, Matthew D., Tadahiro Shimazu, Enxuan Jing, Carrie A. Grueter, Amy M. Collins, Bradley Aouizerat, Alena Stančáková, et al. “SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.” Mol Cell 44, no. 2 (October 21, 2011): 177–90. https://doi.org/10.1016/j.molcel.2011.07.019.
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    • Kovalik, Jean-Paul, Dorothy Slentz, Robert D. Stevens, William E. Kraus, Joseph A. Houmard, James B. Nicoll, Y Renee Lea-Currie, et al. “Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.” Diabetes 60, no. 7 (July 2011): 1882–93. https://doi.org/10.2337/db10-0427.
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    • Lum, Helen, Richard Sloane, Kim M. Huffman, Virginia B. Kraus, Dana K. Thompson, William E. Kraus, James R. Bain, et al. “Plasma acylcarnitines are associated with physical performance in elderly men.” J Gerontol a Biol Sci Med Sci 66, no. 5 (May 2011): 548–53. https://doi.org/10.1093/gerona/glr006.
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    • Zachwieja, Jeffrey J., Amr S. Ragab, JohnEric W. Smith, Mark Pirner, Michael M. Muehlbauer, Robert D. Stevens, Mark D. Butler, and Christopher B. Newgard. “Exercise Induced Elevation of Plasma Acylcarnitines is a Metabolic Signature for Endurance Trained Men.” Medicine & Science in Sports & Exercise 43, no. Suppl 1 (May 2011): 812–13. https://doi.org/10.1249/01.mss.0000402262.42710.ba.
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    • Laferrère, Blandine, David Reilly, Sara Arias, Nicholas Swerdlow, Prakash Gorroochurn, Baani Bawa, Mousumi Bose, et al. “Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.” Sci Transl Med 3, no. 80 (April 27, 2011): 80re2. https://doi.org/10.1126/scitranslmed.3002043.
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    • Kien, C Lawrence, Karen I. Everingham, Robert D Stevens, Naomi K. Fukagawa, and Deborah M. Muoio. “Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects.” Obesity (Silver Spring) 19, no. 2 (February 2011): 305–11. https://doi.org/10.1038/oby.2010.135.
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    • Redman, Leanne M., Kim M. Huffman, Lawrence R. Landerman, Carl F. Pieper, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, et al. “Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women.” J Clin Endocrinol Metab 96, no. 2 (February 2011): E312–21. https://doi.org/10.1210/jc.2010-1971.
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    • Huffman, Kim M., Cris A. Slentz, Lori A. Bateman, Dana Thompson, Michael J. Muehlbauer, James R. Bain, Robert D. Stevens, et al. “Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity.” Diabetes Care 34, no. 1 (January 2011): 174–76. https://doi.org/10.2337/dc10-0709.
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    • Millington, David S., and Robert D. Stevens. “Acylcarnitines: analysis in plasma and whole blood using tandem mass spectrometry.” Methods Mol Biol 708 (2011): 55–72. https://doi.org/10.1007/978-1-61737-985-7_3.
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    • Louet, Jean-Francois, Atul R. Chopra, Jorn V. Sagen, Jie An, Brian York, Mounia Tannour-Louet, Pradip K. Saha, et al. “The coactivator SRC-1 is an essential coordinator of hepatic glucose production.” Cell Metab 12, no. 6 (December 1, 2010): 606–18. https://doi.org/10.1016/j.cmet.2010.11.009.
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    • Newgard, C. B., R. D. Stevens, B. R. Wenner, S. C. Burgess, O. Ilkayeva, M. J. Muehlbauer, A. Dean Sherry, and J. R. Bain. “Comprehensive Metabolic Analysis for Understanding of Disease,” December 1, 2010, 97–107. https://doi.org/10.1016/B978-0-12-374934-5.00009-X.
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    • Wanic, K., A. Pazderska, S. Shah, D. O’Hanlon, J. R. Bain, R. D. Stevens, C. B. Newgard, and J. J. Nolan. “Early onset type 2 diabetes subjects have a metabolic signatures distinguishing them from BMI-matched normoglycaemic individuals.” Irish Journal of Medical Science 179 (November 1, 2010): 517–517.
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    • Rey, Federico E., Jeremiah J. Faith, James Bain, Michael J. Muehlbauer, Robert D. Stevens, Christopher B. Newgard, and Jeffrey I. Gordon. “Dissecting the in vivo metabolic potential of two human gut acetogens.” J Biol Chem 285, no. 29 (July 16, 2010): 22082–90. https://doi.org/10.1074/jbc.M110.117713.
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    • Ellis, Jessica M., Lei O. Li, Pei-Chi Wu, Timothy R. Koves, Olga Ilkayeva, Robert D. Stevens, Steven M. Watkins, Deborah M. Muoio, and Rosalind A. Coleman. “Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis.” Cell Metab 12, no. 1 (July 7, 2010): 53–64. https://doi.org/10.1016/j.cmet.2010.05.012.
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    • Shah, Svati H., James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, David R. Crosslin, Carol Haynes, Jennifer Dungan, et al. “Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.” Circ Cardiovasc Genet 3, no. 2 (April 2010): 207–14. https://doi.org/10.1161/CIRCGENETICS.109.852814.
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    • Tai, E. S., M. L. S. Tan, R. D. Stevens, Y. L. Low, M. J. Muehlbauer, D. L. M. Goh, O. R. Ilkayeva, et al. “Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men.” Diabetologia 53, no. 4 (April 2010): 757–67. https://doi.org/10.1007/s00125-009-1637-8.
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    • Wang, May-yun, Lijun Chen, Gregory O. Clark, Young Lee, Robert D. Stevens, Olga R. Ilkayeva, Brett R. Wenner, et al. “Leptin therapy in insulin-deficient type I diabetes.” Proc Natl Acad Sci U S A 107, no. 11 (March 16, 2010): 4813–19. https://doi.org/10.1073/pnas.0909422107.
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    • Hirschey, Matthew D., Tadahiro Shimazu, Eric Goetzman, Enxuan Jing, Bjoern Schwer, David B. Lombard, Carrie A. Grueter, et al. “SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.” Nature 464, no. 7285 (March 4, 2010): 121–25. https://doi.org/10.1038/nature08778.
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    • Newgard, C. B., R. D. Stevens, B. R. Wenner, S. C. Burgess, O. Ilkayeva, M. J. Muehlbauer, A. D. Sherry, and J. R. Bain. “Comprehensive Metabolic Analysis for Understanding of Disease Mechanisms,” December 1, 2009, 180–92. https://doi.org/10.1016/B978-0-12-369420-1.00015-9.
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    • Dong, Bingning, Pradip K. Saha, Wendong Huang, Wenling Chen, Lutfi A. Abu-Elheiga, Salih J. Wakil, Robert D. Stevens, et al. “Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.” Proc Natl Acad Sci U S A 106, no. 44 (November 3, 2009): 18831–36. https://doi.org/10.1073/pnas.0909731106.
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    • Bain, James R., Robert D. Stevens, Brett R. Wenner, Olga Ilkayeva, Deborah M. Muoio, and Christopher B. Newgard. “Metabolomics applied to diabetes research: moving from information to knowledge.” Diabetes 58, no. 11 (November 2009): 2429–43. https://doi.org/10.2337/db09-0580.
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    • Huffman, Kim M., Svati H. Shah, Robert D. Stevens, James R. Bain, Michael Muehlbauer, Cris A. Slentz, Charles J. Tanner, et al. “Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.” Diabetes Care 32, no. 9 (September 2009): 1678–83. https://doi.org/10.2337/dc08-2075.
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    • Young, S. P., J. L. Goldstein, E. Winchester, D. Sanders, R. D. Stevens, D. D. Koeberl, and D. S. Millington. “SULFITE OXIDASE AND MOLYBDENUM COFACTOR DEFICIENCIES: CLINICAL EXPERIENCE OF A DIAGNOSTIC LABORATORY AND LITERATURE REVIEW.” Molecular Genetics and Metabolism 98, no. 1–2 (September 1, 2009): 139–139.
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    • Noland, Robert C., Timothy R. Koves, Sarah E. Seiler, Helen Lum, Robert M. Lust, Olga Ilkayeva, Robert D. Stevens, Fausto G. Hegardt, and Deborah M. Muoio. “Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control.” J Biol Chem 284, no. 34 (August 21, 2009): 22840–52. https://doi.org/10.1074/jbc.M109.032888.
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    • Malakauskas, Sandra M., Wissam M. Kourany, Xiao Yin Zhang, Danhong Lu, Robert D. Stevens, Timothy R. Koves, Hans E. Hohmeier, Deborah M. Muoio, Christopher B. Newgard, and Thu H. Le. “Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.” Mol Endocrinol 23, no. 6 (June 2009): 881–92. https://doi.org/10.1210/me.2008-0274.
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    • Newgard, C. B., J. An, J. R. Bain, M. J. Muehlbauer, R. D. Stevens, L. F. Lien, A. M. Haqq, et al. “A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance (DOI:10.1016/j.cmet.2009.02.002).” Cell Metabolism 9, no. 6 (May 14, 2009): 565–66. https://doi.org/10.1016/j.cmet.2009.05.001.
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    • Turer, Aslan T., Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Johannes van der Westhuizen, Joseph P. Mathew, Debra A. Schwinn, Donald D. Glower, Christopher B. Newgard, and Mihai V. Podgoreanu. “Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.” Circulation 119, no. 13 (April 7, 2009): 1736–46. https://doi.org/10.1161/CIRCULATIONAHA.108.816116.
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    • Newgard, Christopher B., Jie An, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Lillian F. Lien, Andrea M. Haqq, et al. “A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.” Cell Metab 9, no. 4 (April 2009): 311–26. https://doi.org/10.1016/j.cmet.2009.02.002.
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    • Lamers, Yvonne, Jerry Williamson, Maria Ralat, Eoin P. Quinlivan, Lesa R. Gilbert, Christine Keeling, Robert D. Stevens, et al. “Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women.” J Nutr 139, no. 3 (March 2009): 452–60. https://doi.org/10.3945/jn.108.099184.
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    • Zhang, Haoyue, Robert D. Stevens, Sarah P. Young, Richard Surwit, Anastasia Georgiades, Raymond Boston, and David S. Millington. “A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer.” Clin Chem 55, no. 3 (March 2009): 527–32. https://doi.org/10.1373/clinchem.2008.113654.
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    • Lien, Lillian F., Andrea M. Haqq, Michelle Arlotto, Cris A. Slentz, Michael J. Muehlbauer, Ross L. McMahon, James Rochon, et al. “The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain.” Omics 13, no. 1 (February 2009): 21–35. https://doi.org/10.1089/omi.2008.0035.
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    • Makowski, Liza, Robert C. Noland, Timothy R. Koves, Weibing Xing, Olga R. Ilkayeva, Michael J. Muehlbauer, Robert D. Stevens, and Deborah M. Muoio. “Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation.” Faseb J 23, no. 2 (February 2009): 586–604. https://doi.org/10.1096/fj.08-119420.
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    • Shah, Svati H., Elizabeth R. Hauser, James R. Bain, Michael J. Muehlbauer, Carol Haynes, Robert D. Stevens, Brett R. Wenner, et al. “High heritability of metabolomic profiles in families burdened with premature cardiovascular disease.” Mol Syst Biol 5 (2009): 258. https://doi.org/10.1038/msb.2009.11.
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    • Ferrara, Christine T., Ping Wang, Elias Chaibub Neto, Robert D. Stevens, James R. Bain, Brett R. Wenner, Olga R. Ilkayeva, et al. “Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.” Plos Genet 4, no. 3 (March 14, 2008): e1000034. https://doi.org/10.1371/journal.pgen.1000034.
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    • Koves, Timothy R., John R. Ussher, Robert C. Noland, Dorothy Slentz, Merrie Mosedale, Olga Ilkayeva, James Bain, et al. “Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.” Cell Metab 7, no. 1 (January 2008): 45–56. https://doi.org/10.1016/j.cmet.2007.10.013.
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    • Levin, Malin C., Mara Monetti, Matthew J. Watt, Mini P. Sajan, Robert D. Stevens, James R. Bain, Christopher B. Newgard, and Robert V. Farese. “Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.” Am J Physiol Endocrinol Metab 293, no. 6 (December 2007): E1772–81. https://doi.org/10.1152/ajpendo.00158.2007.
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    • Remington, Nicole, Robert D. Stevens, Randall S. Wells, Aleta Holn, Suraj Dhungana, Celine H. Taboy, Alvin L. Crumbliss, Robert Henkens, and Celia Bonaventura. “Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins.” Gene 398, no. 1–2 (August 15, 2007): 123–31. https://doi.org/10.1016/j.gene.2007.02.050.
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    • Monetti, Mara, Malin C. Levin, Matthew J. Watt, Mini P. Sajan, Stephen Marmor, Brian K. Hubbard, Robert D. Stevens, et al. “Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.” Cell Metab 6, no. 1 (July 2007): 69–78. https://doi.org/10.1016/j.cmet.2007.05.005.
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    • Zhang, Yong-Mei, Shigeru Chohnan, Kristopher G. Virga, Robert D. Stevens, Olga R. Ilkayeva, Brett R. Wenner, James R. Bain, et al. “Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.” Chem Biol 14, no. 3 (March 2007): 291–302. https://doi.org/10.1016/j.chembiol.2007.01.013.
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    • Marx, Christine E., William T. Trost, Lawrence J. Shampine, Robert D. Stevens, Christine M. Hulette, David C. Steffens, John F. Ervin, et al. “The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.” Biol Psychiatry 60, no. 12 (December 15, 2006): 1287–94. https://doi.org/10.1016/j.biopsych.2006.06.017.
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    • Ronnebaum, Sarah M., Olga Ilkayeva, Shawn C. Burgess, Jamie W. Joseph, Danhong Lu, Robert D. Stevens, Thomas C. Becker, A Dean Sherry, Christopher B. Newgard, and Mette V. Jensen. “A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.” J Biol Chem 281, no. 41 (October 13, 2006): 30593–602. https://doi.org/10.1074/jbc.M511908200.
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    • Marx, Christine E., Robert D. Stevens, Lawrence J. Shampine, Veska Uzunova, William T. Trost, Marian I. Butterfield, Mark W. Massing, Robert M. Hamer, A Leslie Morrow, and Jeffrey A. Lieberman. “Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics.” Neuropsychopharmacology 31, no. 6 (June 2006): 1249–63. https://doi.org/10.1038/sj.npp.1300952.
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    • Batinić-Haberle, Ines, Ivan Spasojević, Robert D. Stevens, Bruce Bondurant, Ayako Okado-Matsumoto, Irwin Fridovich, Zeljko Vujasković, and Mark W. Dewhirst. “New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.” Dalton Trans, no. 4 (January 28, 2006): 617–24. https://doi.org/10.1039/b513761f.
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    • Bonaventura, Celia, Gerald Godette, Robert Stevens, Michael Brenowitz, and Robert Henkens. “Overproduction of alpha chains provides a proton-insensitive component to the bluefish hemoglobin system.” J Biol Chem 280, no. 49 (December 9, 2005): 40509–14. https://doi.org/10.1074/jbc.M505353200.
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    • Haqq, Andrea M., Lillian F. Lien, Jarol Boan, Michelle Arlotto, Cris A. Slentz, Michael J. Muehlbauer, James Rochon, et al. “The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design.” Contemp Clin Trials 26, no. 6 (December 2005): 616–25. https://doi.org/10.1016/j.cct.2005.09.003.
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    • Hulver, Matthew W., Jason R. Berggren, Michael J. Carper, Makoto Miyazaki, James M. Ntambi, Eric P. Hoffman, John P. Thyfault, et al. “Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans.” Cell Metab 2, no. 4 (October 2005): 251–61. https://doi.org/10.1016/j.cmet.2005.09.002.
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    • He, Yikun, Ru-Hang Tang, Yi Hao, Robert D. Stevens, Charles W. Cook, Sun M. Ahn, Liufang Jing, et al. “Nitric oxide represses the Arabidopsis floral transition.” Science 305, no. 5692 (September 24, 2004): 1968–71. https://doi.org/10.1126/science.1098837.
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    • Batinić-Haberle, Ines, Ivan Spasojević, Robert D. Stevens, Peter Hambright, Pedatsur Neta, Ayako Okado-Matsumoto, and Irwin Fridovich. “New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins.” Dalton Trans, no. 11 (June 7, 2004): 1696–1702. https://doi.org/10.1039/b400818a.
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    • Quan, Hui, Krairerk Athirakul, William C. Wetsel, Gonzalo E. Torres, Robert Stevens, Y. T. Chen, Thomas M. Coffman, and Marc G. Caron. “Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.” Mol Cell Biol 24, no. 10 (May 2004): 4166–73. https://doi.org/10.1128/mcb.24.10.4166-4173.2004.
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    • An, Jie, Deborah M. Muoio, Masakazu Shiota, Yuka Fujimoto, Gary W. Cline, Gerald I. Shulman, Timothy R. Koves, Robert Stevens, David Millington, and Christopher B. Newgard. “Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.” Nat Med 10, no. 3 (March 2004): 268–74. https://doi.org/10.1038/nm995.
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    • Wu, Jer-Yuarn, Hsiao-Jung Kao, Sing-Chung Li, Robert Stevens, Steven Hillman, David Millington, and Yuan-Tsong Chen. “ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease.” J Clin Invest 113, no. 3 (February 2004): 434–40. https://doi.org/10.1172/JCI19574.
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    • Young, Sarah P., Dietrich Matern, Niels Gregersen, Robert D. Stevens, Deeksha Bali, Hui-Ming Liu, Dwight D. Koeberl, and David S. Millington. “A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency.” Clin Chim Acta 337, no. 1–2 (November 2003): 103–13. https://doi.org/10.1016/j.cccn.2003.07.006.
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    • Young, Sarah P., Robert D. Stevens, Yan An, Yuan-Tsong Chen, and David S. Millington. “Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry.” Anal Biochem 316, no. 2 (May 15, 2003): 175–80. https://doi.org/10.1016/s0003-2697(03)00056-3.
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    • An, Y., R. D. Stevens, J. Muenzer, J. T. R. Clarke, and D. S. Millington. “An LC-MS/MS method for determination of glycosaminoglycan content of urine for the diagnosis of mucopolysaccharidoses.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, December 1, 2002, 597–98.
    • Young, S. P., Y. An, J. Van Hove, R. D. Stevens, Y. T. Chen, and D. S. Millington. “Isomeric oligosaccharide analysis using hydrophilic interaction LC-ESI-MS/MS.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, December 1, 2002, 413–14.
    • Batinić-Haberle, I., I. Spasojević, R. D. Stevens, P. Hambright, and I. Fridovich. “Manganese(III) meso-tetrakis(ortho-N-alkylpyridyl)porphyrins. Synthesis, characterization, and catalysis of O2/^·- dismutation.” Journal of the Chemical Society, Dalton Transactions, no. 13 (July 18, 2002): 2689–96.
    • Bonaventura, Celia, Gerald Godette, Giulia Ferruzzi, Shirley Tesh, Robert D. Stevens, and Robert Henkens. “Responses of normal and sickle cell hemoglobin to S-nitroscysteine: implications for therapeutic applications of NO in treatment of sickle cell disease.” Biophys Chem 98, no. 1–2 (July 10, 2002): 165–81. https://doi.org/10.1016/s0301-4622(02)00092-3.
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    • Bonaventura, Celia, Celine H. Taboy, Philip S. Low, Robert D. Stevens, Celine Lafon, and Alvin L. Crumbliss. “Heme redox properties of S-nitrosated hemoglobin A0 and hemoglobin S: implications for interactions of nitric oxide with normal and sickle red blood cells.” J Biol Chem 277, no. 17 (April 26, 2002): 14557–63. https://doi.org/10.1074/jbc.M107658200.
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    • Spasojević, I., I. Batinić-Haberle, R. D. Stevens, P. Hambright, A. N. Thorpe, J. Grodkowski, P. Neta, and I. Fridovich. “Manganese(III) biliverdin IX dimethyl ester: a powerful catalytic scavenger of superoxide employing the Mn(III)/Mn(IV) redox couple.” Inorg Chem 40, no. 4 (February 12, 2001): 726–39. https://doi.org/10.1021/ic0004986.
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    • Kachadourian, R., N. Srinivasan, C. A. Haney, and R. D. Stevens. “An LDI-TOF and ESI mass spectrometry study of a series of β-substituted cationic metalloporphyrins.” Journal of Porphyrins and Phthalocyanines 5, no. 6 (January 1, 2001): 507–11. https://doi.org/10.1002/jpp.354.
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    • Spasojevic, I., R. D. Stevens, and I. Batinic-Haberle. “Biliverdin is preorganized for dimeric metal complex formation, therefore for its antioxidant role in vitro.” Free Radical Biology and Medicine 31 (January 1, 2001): S20–S20.
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    • Spasojević, I., H. Boukhalfa, R. D. Stevens, and A. L. Crumbliss. “Aqueous solution speciation of Fe(III) complexes with dihydroxamate siderophores alcaligin and rhodotorulic acid and synthetic analogues using electrospray ionization mass spectrometry.” Inorg Chem 40, no. 1 (January 1, 2001): 49–58. https://doi.org/10.1021/ic991390x.
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    • Stevens, R. D., S. L. Hillman, S. Worthy, D. Sanders, and D. S. Millington. “Assay for free and total carnitine in human plasma using tandem mass spectrometry.” Clin Chem 46, no. 5 (May 2000): 727–29.
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    • Batinic-Haberle, I., R. D. Stevens, and I. Fridovich. “Electrospray mass spectrometry of isomeric tetrakis(N-alkylpyridyl)porphyrins and their manganese(III) and iron(III) complexes.” Journal of Porphyrins and Phthalocyanines 4, no. 3 (January 1, 2000): 217–27. https://doi.org/10.1002/(SICI)1099-1409(200004/05)4:3<217::AID-JPP198>3.0.CO;2-E.
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    • Batinić-Haberle, I., R. D. Stevens, and I. Fridovich. “Electrospray mass spectrometry of isomeric tetrakis(N-alkylpyridyl)porphyrins and their manganese(III) and iron(III) complexes.” Journal of Porphyrins and Phthalocyanines 4, no. 3 (January 1, 2000): 217–27. https://doi.org/10.1002/(SICI)1099-1409(200004/05)4:3<217::AID-JPP198>3.3.CO;2-5.
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    • Balendiran, G. K., J. A. Molina, Y. Xu, J. Torres-Martinez, R. Stevens, P. J. Focia, A. E. Eakin, J. C. Sacchettini, and S. P. Craig. “Erratum: Ternary complex structure of human HGPRTase, PRPP, Mg²⁺, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding (Protein Science (1999) 8:5 (1023-1031)).” Protein Science 8, no. 12 (December 1, 1999): 2815.
    • Bonaventura, C., G. Ferruzzi, S. Tesh, and R. D. Stevens. “Effects of S-nitrosation on oxygen binding by normal and sickle cell hemoglobin.” J Biol Chem 274, no. 35 (August 27, 1999): 24742–48. https://doi.org/10.1074/jbc.274.35.24742.
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    • Crumbliss, A. L. L., H. Boukhalfa, I. Spasojevic, and R. D. Stevens. “Fe(III) dissociation mechanisms for dohydroxamic acid siderophore complexes.” Abstracts of Papers of the American Chemical Society 218 (August 22, 1999): U860–U860.
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    • Balendiran, G. K., J. A. Molina, Y. Xu, J. Torres-Martinez, R. Stevens, P. J. Focia, A. E. Eakin, J. C. Sacchettini, and S. P. Craig. “Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding.” Protein Sci 8, no. 5 (May 1999): 1023–31. https://doi.org/10.1110/ps.8.5.1023.
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    • Batinic-Haberle, I., R. D. Stevens, and I. Fridovich. “Porphyrin-based SOD mimics. Electrospray mass spectroscopy of Mn(III) and Fe(III) isomeric tetrakis-(N-alkylpyridyl) porphyrins.” Free Radical Biology and Medicine 27 (January 1, 1999): S18–S18.
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    • Morris, D. P., R. D. Stevens, and A. L. Greenleaf. “Protonation of the neutral repeats of the RNA polymerase II CTD.” Biochem Biophys Res Commun 245, no. 1 (April 7, 1998): 53–58. https://doi.org/10.1006/bbrc.1998.8373.
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    • Russell, B. G., W. E. Moddeman, J. C. Birkbeck, S. E. Wright, D. S. Millington, R. D. Stevens, and K. E. Dombrowski. “Surface structure of human mucin using X-ray photoelectron spectroscopy.” Biospectroscopy 4, no. 4 (1998): 257–66. https://doi.org/10.1002/(sici)1520-6343(1998)4:4<257::aid-bspy4>3.0.co;2-#.
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    • Pirie-Shepherd, S. R., R. D. Stevens, N. L. Andon, J. J. Enghild, and S. V. Pizzo. “Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2.” J Biol Chem 272, no. 11 (March 14, 1997): 7408–11. https://doi.org/10.1074/jbc.272.11.7408.
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    • Palm, L., L. T. Burka, P. Højrup, R. D. Stevens, and K. B. Tomer. “Identification of five hemoglobins in B6C3F1 mice by mass spectrometry and sequence analysis.” Int J Biochem Cell Biol 28, no. 12 (December 1996): 1319–26. https://doi.org/10.1016/s1357-2725(96)00090-8.
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    • Calderone, T. L., R. D. Stevens, and T. G. Oas. “High-level misincorporation of lysine for arginine at AGA codons in a fusion protein expressed in Escherichia coli.” J Mol Biol 262, no. 4 (October 4, 1996): 407–12. https://doi.org/10.1006/jmbi.1996.0524.
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    • Kitareewan, S., L. T. Burka, K. B. Tomer, C. E. Parker, L. J. Deterding, R. D. Stevens, B. M. Forman, et al. “Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR.” Mol Biol Cell 7, no. 8 (August 1996): 1153–66. https://doi.org/10.1091/mbc.7.8.1153.
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    • Benov, L. T., W. F. Beyer, R. D. Stevens, and I. Fridovich. “Purification and characterization of the Cu,Zn SOD from Escherichia coli.” Free Radic Biol Med 21, no. 1 (1996): 117–21. https://doi.org/10.1016/0891-5849(95)02217-1.
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    • Morris, D. P., R. D. Stevens, D. J. Wright, and D. W. Stafford. “Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate.” J Biol Chem 270, no. 51 (December 22, 1995): 30491–98. https://doi.org/10.1074/jbc.270.51.30491.
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    • Caudle, M. T., R. D. Stevens, and A. L. Crumbliss. “A Monomer-to-Dimer Shift in a Series of 1:1 Ferric Dihydroxamates Probed by Electrospray Mass Spectrometry.” Inorganic Chemistry 33, no. 26 (December 1, 1994): 6111–15. https://doi.org/10.1021/ic00104a020.
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    • Bonaventura, C., J. Bonaventura, R. Stevens, and D. Millington. “Acrylamide in polyacrylamide gels can modify proteins during electrophoresis.” Anal Biochem 222, no. 1 (October 1994): 44–48. https://doi.org/10.1006/abio.1994.1451.
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    • Faulkner, K. M., R. D. Stevens, and I. Fridovich. “Characterization of Mn(III) complexes of linear and cyclic desferrioxamines as mimics of superoxide dismutase activity.” Arch Biochem Biophys 310, no. 2 (May 1, 1994): 341–46. https://doi.org/10.1006/abbi.1994.1176.
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    • Stevens, R. D., J. Bonaventura, C. Bonaventura, T. R. Fennel, and D. S. Millington. “Application of electrospray ionization mass spectrometry for analysis of haemoglobin adducts with acrylonitrile.” Biochem Soc Trans 22, no. 2 (May 1994): 543–47. https://doi.org/10.1042/bst0220543.
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    • Caudle, M. T., R. D. Stevens, and A. L. Crumbliss. “Electrospray Mass Spectrometry Study of 1:1 Ferric Dihydroxamates.” Inorganic Chemistry 33, no. 5 (March 1, 1994): 843–44. https://doi.org/10.1021/ic00083a001.
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    • Wang, Y., N. Agrwal, A. E. Eckhardt, R. D. Stevens, and R. L. Hill. “The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues.” J Biol Chem 268, no. 31 (November 5, 1993): 22979–83.
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    • Rabinowitch, H. D., D. Sklan, D. H. Chace, R. D. Stevens, and I. Fridovich. “Escherichia coli produces linoleic acid during late stationary phase.” J Bacteriol 175, no. 17 (September 1993): 5324–28. https://doi.org/10.1128/jb.175.17.5324-5328.1993.
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    • Stevens, R. D., A. A. Ribeiro, L. Lack, and P. G. Killenberg. “Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts.” J Lipid Res 33, no. 1 (January 1992): 21–29.
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    • Stevens, R. D., L. Lack, and P. G. Killenberg. “Calcium binding by monosulfate esters of taurochenodeoxycholate.” J Lipid Res 32, no. 4 (April 1991): 621–27.
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    • CUCCHIARO, G., G. D. BRANUM, P. G. KILLENBERG, R. D. STEVENS, R. BOLLINGER, R. MCCANN, R. EPSTEIN, and W. MEYERS. “2 DIMENSIONAL GEL-ELECTROPHORETIC PATTERNS OF BILIARY PROTEIN SECRETION AFTER LIVER-TRANSPLANTATION.” Hepatology 10, no. 4 (October 1, 1989): 659–659.
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    • STEVENS, R. D., M. P. TYOR, F. L. DUNN, and P. G. KILLENBERG. “THE RELATIVE EFFECT OF LOVASTATIN (L) ON TOTAL (TC), LOW-DENSITY LIPOPROTEIN (LDL-C) CHOLESTEROL AND ON THE BILIARY CHOLESTEROL SATURATION INDEX (SI) IN SUBJECTS WITH GALLSTONES.” Hepatology 10, no. 4 (October 1, 1989): 735–735.
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    • Stevens, R. D., L. Lack, R. H. Collins, W. C. Meyers, and P. G. Killenberg. “Effects of monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids in hamsters.” J Lipid Res 30, no. 5 (May 1989): 673–79.
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    • STEVENS, R. D., L. LACK, and P. G. KILLENBERG. “CALCIUM-BINDING BY MONOSULFATE ESTERS OF TAUROCHENODEOXYCHOLATE.” Clinical Research 37, no. 2 (April 1, 1989): A539–A539.
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    • STEVENS, R. D., L. LACK, W. C. MEYERS, and P. G. KILLENBERG. “CHOLERESIS AND BILIARY LIPID EXCRETION IN UNANESTHETIZED HAMSTERS FOLLOWING PORTAL INFUSION OF MONOSULFATE ESTERS OF TAUROCHENODEOXYCHOLATE.” Gastroenterology 92, no. 5 (May 1, 1987): 1783–1783.
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    • Killenberg, P. G., R. D. Stevens, R. F. Wildermann, and N. M. Wildermann. “The laboratory method as a variable in the interpretation of serum bilirubin fractionation.” Gastroenterology 78, no. 5 Pt 1 (May 1980): 1011–15.
    • Mansbach, C. M., D. Newton, and R. D. Stevens. “Fat digestion in patients with bile acid malabsorption but minimal steatorrhea.” Dig Dis Sci 25, no. 5 (May 1980): 353–62. https://doi.org/10.1007/BF01308059.
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    • Killenberg, P. G., R. D. Stevens, R. F. Wildermann, and N. M. Wildermann. “The laboratory method as a variable in the interpretation of serum bilirubin fractionation.” Gastroenterology 78, no. 5 PART 1 (January 1, 1980): 1011–15. https://doi.org/10.1016/0016-5085(80)90785-4.
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    • THIEU, N., and R. D. STEVENS. “BILE-SALT COMPOSITION MAY MEDIATE CHOLESTEROL PRECIPITATION IN BILE.” Gastroenterology 78, no. 5 (January 1, 1980): 1277–1277.
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    • SMITH, P., L. B. GILMAN, R. D. STEVENS, and C. V. D. HARGRAVE. “ESR STUDY OF THE AZO-COMPOUND PHOTOINITIATED POLYMERIZATION OF METHACRYLONITRILE.” Abstracts of Papers of the American Chemical Society, no. SEP (January 1, 1979): 89–89.
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    • Long, T. T., L. Jakoi, R. Stevens, and S. Quarfordt. “The sources of rat biliary cholesterol and bile acid.” J Lipid Res 19, no. 7 (September 1978): 872–78.
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    • Mansbach, C. M., J. D. Shelburne, R. D. Stevens, and W. O. Dobbins. “Lymph-node bacilliform bodies resembling those of Whipple's disease in a patient without intestinal involvement.” Ann Intern Med 89, no. 1 (July 1978): 64–66. https://doi.org/10.7326/0003-4819-89-1-64.
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    • Smith, P., L. B. Gilman, R. D. Stevens, and C. V. De Hargrave. “EPR study of the photoinitiated polymerization of styrene.” Journal of Magnetic Resonance (1969) 29, no. 3 (January 1, 1978): 545–52. https://doi.org/10.1016/0022-2364(78)90012-4.
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    • Stevens, R. D. “An electron spin resonance study of cholestane spin label in aqueous mixtures of biliary lipids.” J Lipid Res 18, no. 4 (July 1977): 417–22.
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    • STEVENS, R. D. “GEL-PERMEATION OF AGGREGATES FORMED BY BILIARY LIPIDS.” Gastroenterology 72, no. 5 (January 1, 1977): 1167–1167.
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    • Stevens, R. D. “An electron spin resonance study of cholestane spin label in aqueous mixtures of biliary lipids.” Journal of Lipid Research 18, no. 4 (January 1, 1977): 417–22.
    • Ashworth, B., B. C. Gilbert, P. Smith, R. D. Stevens, and R. A. Kaba. “Magnetic nonequivalence in radicals from acrylic derivatives.” Journal of Magnetic Resonance (1969) 19, no. 3 (January 1, 1975): 398–400. https://doi.org/10.1016/0022-2364(75)90056-6.
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    • Smith, P., R. D. Stevens, and L. B. Gilman. “Electron paramagnetic resonance study of the photoinitiated polymerization of methacrylonitrile.” The Journal of Physical Chemistry 79, no. 24 (January 1, 1975): 2688–93. https://doi.org/10.1021/j100591a019.
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    • Smith, P., and R. D. Stevens. “Electron paramagnetic resonance spectroscopic study of the photoinitiated polymerization of alkyl methacrylates.” Journal of Physical Chemistry 76, no. 22 (January 1, 1972): 3141–52. https://doi.org/10.1021/j100666a008.
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    • Smith, P., R. D. Stevens, and R. A. Kaba. “Electron paramagnetic resonance spectroscopic study of radical cations from hydrazine, methylhydrazine, and dimethylhydrazines.” The Journal of Physical Chemistry 75, no. 13 (January 1, 1971): 2048–55. https://doi.org/10.1021/j100682a024.
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  • Conference Papers

    • Aras, Mandar A., Damian M. Craig, Carol Haynes, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga Ilkayeva, et al. “Peripheral Metabolite Profiles Predict Cardiomyopathy in a Cohort of Cardiac Catheterization Patients.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Tripathy, Sasmita, Robert D. Stevens, James R. Bain, Christopher B. Newgard, and Donald B. Jump. “Elevated hepatic fatty acid elongase-5 (Elovl5) attenuates fatty liver in high fat diet induced obese mice.” In Faseb Journal, Vol. 27. FEDERATION AMER SOC EXP BIOL, 2013.
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    • Glynn, Erin L., Jie An, Li-Ping Wang, Olga R. Ilkayeva, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, et al. “Caloric restriction, aerobic exercise or a combination improves metabolic profiles following diet-induced obesity.” In Faseb Journal, Vol. 26, 2012.
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    • Wanic, K., A. Pazderska, S. Shah, D. O’Hanlon, J. R. Bain, R. D. Stevens, C. B. Newgard, and J. J. Nolan. “Distinctive metabolic signature in subjects with early onset type 2 diabetes.” In Diabetologia, Vol. 53. SPRINGER, 2010.
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    • Shah, Svati H., David R. Crosslin, Sarah Nelson, Carol Haynes, Christy L. Boling, James Bain, Michael Muehlbauer, et al. “Metabolomic Profiles Are Associated With Baseline Insulin Resistance and Improvement in Insulin Resistance With Weight Loss in the WLM Trial.” In Circulation, 120:S467–S467. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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    • Shah, Svati H., Jie-Lena Sun, Karen Pieper, David R. Crosslin, Carol Haynes, James R. Bain, Michael Muehlbauer, et al. “Plasma Metabolomic Profiles Predict Future Cardiovascular Events.” In Circulation, 120:S466–67. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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    • Huffman, Kim M., Svati H. Shah, Robert D. Stevens, James R. Bain, and William E. Kraus. “Circulating metabolic intermediates are markers of insulin resistance in a population at risk for coronary heart disease.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.
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    • Shah, Svati H., James Bain, Michael J. Muehlbauer, Robert D. Stevens, Brett R. Wenner, Lauren C. Naliboff, Carol Haynes, et al. “Peripheral blood metabolic signatures are markers of coronary artery disease and myocardial infarction.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.
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    • Naylor, Jennifer C., Victoria M. Payne, Christine M. Hulette, Lawrence J. Shampine, Robert D. Stevens, John F. Ervin, Mark W. Massing, et al. “Cerebrospinal fluid DHEA levels are elevated in Alzheimer's disease, related to neuropathological disease stage, and correlated with brain DHEA levels.” In Biological Psychiatry, 61:142S-142S. ELSEVIER SCIENCE INC, 2007.
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    • Hershfield, Michael S., John S. Sundy, Robert D. Stevens, Nancy J. Ganson, Susan J. Kelly, and Edna Scarlett. “Measurement of exchangeable uric acid pool size: Potential utility for evaluating the therapy of gout.” In Arthritis and Rheumatism, 54:S318–S318. WILEY-LISS, 2006.
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    • He, Y., R. Tang, Y. Hao, R. D. Stevens, and Z. M. Pei. “Nitric oxide represses arabidopsis flowering.” In Integrative and Comparative Biology, 45:1010–1010. OXFORD UNIV PRESS INC, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, A. L. Morrow, V. Uzunova, T. T. William, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in posterior cingulate and parietal cortex in subjects with schizophrenia and bipolar disorder: Potential gender specificity.” In Biological Psychiatry, 57:6S-6S. ELSEVIER SCIENCE INC, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, A. L. Morrow, V. Uzunova, W. T. Trost, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in schizophrenia and bipolar disorder: Negative ion chemical ionization gas chromatography/mass spectrometry investigations in posterior cingulate and parietal cortex.” In Schizophrenia Bulletin, 31:253–253. OXFORD UNIV PRESS, 2005.
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    • Batinic-Haberle, I., I. Spasojevic, R. D. Stevens, B. Bondurant, A. Okado-Matsumoto, I. Fridovich, and M. W. Dewhirst. “New Mn(III) porphyrins with high superoxide disproportionating ability.” In Free Radical Biology and Medicine, 39:S19–S19. ELSEVIER SCIENCE INC, 2005.
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    • Marx, C. E., L. J. Shampine, R. D. Stevens, W. T. Trost, A. L. Morrow, R. M. Hamer, and J. A. Lieberman. “Neuroactive steroid alterations in schizophrenia and bipolar disorder: A negative ion chemical ionization gas chromatography/mass spectrometry investigation in posterior cingulate.” In Neuropsychopharmacology, 29:S172–73. NATURE PUBLISHING GROUP, 2004.
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    • Young, S. P., T. C. Wood, L. S. Almeida, G. S. Salomons, C. Jakobs, R. D. Stevens, D. D. Koeberl, and D. S. Millington. “A comparison of mass spectrometry methods for the measurement of creatine and guanidinoacetate in plasma.” In Molecular Genetics and Metabolism, 81:182–182. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.
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    • Batinic-Haberle, I., I. Spasojevic, R. D. Stevens, P. Hambright, P. Neta, A. Okado-Matsumoto, and I. Fridovich. “Improving bioavailibility of SOD mimics.” In Free Radical Biology and Medicine, 37:S19–20. PERGAMON-ELSEVIER SCIENCE LTD, 2004.
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    • Batinic-Haberle, I., A. Okado-Matsumoto, I. Spasojevic, P. Hambright, R. D. Stevens, P. Neta, and T. Fridovich. “Recent advances in the synthesis and characterization of MN water-soluble porphyrin-based catalytic antioxidants.” In Free Radical Biology and Medicine, 35:S17–18. PERGAMON-ELSEVIER SCIENCE LTD, 2003.
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