Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow, Hand Surgery, Dept Of Orthopaedics, Duke University 2011 - 2012
  • Resident, Plastic Surgery, Johns Hopkins University 2006 - 2011
  • Resident, General Surgery, Johns Hopkins University 2003 - 2006
  • M.D., Vanderbilt University School of Medicine 2003
  • Resident, The Medical Scholars Program, Vanderbilt University 2001 - 2002
• 

  Duke Appointment History

  • Assistant Professor of Orthopaedic Surgery, Orthopaedics, Orthopaedics 2012 - 2017
  • Assistant Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery, Surgery 2012 - 2017
• Expertise
• 

  Subject Headings

  • Adult
  • Arm Injuries
  • Craniocerebral Trauma
  • Fracture
  • Fractures, Malunited
  • Fractures, Ununited
  • Hand Deformities
  • Lymphedema
  • Muscle, Skeletal
  • Orthopedic Procedures
  • Osteotomy
  • Peripheral Nerve Injuries
  • Radius Fractures
  • Range of Motion, Articular
  • Reconstructive Surgical Procedures
  • Retreatment
  • Risk
  • Rupture
  • Surgical Flaps
  • Tendon Injuries
• Research
• 

  Selected Grants

  • Are Perforators the "Lighthouses" of Upper Extremity Peripheral Nerves? awarded by American Society for Surgery of the Hand 2017
  • Fresh Tissue Lab Agreement awarded by Arthrosurface, Inc. 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Conference Papers

    • Mithani, SK, Balch, GC, Wright, J, Washington, K, Beauchamp, RD, & Chapman, WC. (2003, September). Induction of cytotoxicity with proteasome inhibition in hepatocellular carcinoma.  Link to Item
    • Balch, GC, Mithani, SK, Richards, K, Beauchamp, RD, & Kelley, MC. (2002, January). Prospective evaluation of the accuracy of lymphatic mapping and sentinel lymphadenectomy after preoperative therapy for locally advanced breast cancer.  Link to Item

  • Journal Articles

    • Koehler, SM, Matson, AP, Ruch, DS, & Mithani, SK. (2018, September). Neural Perforasomes of the Upper Extremity. Plastic and Reconstructive Surgery ,.  Full Text
    • Federer, AE, Guerrero, EM, Dekker, TJ, Mithani, SK, Aldridge, JM, Ruch, DS, & Richard, MJ. (2018, July 28). Open Reduction Internal Fixation With Transverse Volar Plating for Unstable Proximal Interphalangeal Fracture-Dislocation: The Seatbelt Procedure. Hand (New York, N.Y.) ,, 1558944718790063-null.  Full Text
    • Avashia, YJ, Shammas, RL, Poveromo, LP, Dekker, TJ, Brubacher, JW, Richard, MJ, Ruch, DS, & Mithani, SK. (2018, July). Forearm-Based Turnover Muscle Flaps for Elbow Soft-Tissue Reconstruction: A Comparison of Regional Coverage Based on Distal Flap Perfusion. Plastic and Reconstructive Surgery , 142 (1), 152-157.  Full Text
    • Shammas, RL, Mela, N, Wallace, S, Tong, BC, Huber, J, & Mithani, SK. (2018, July). Conjoint Analysis of Treatment Preferences for Nondisplaced Scaphoid Fractures. The Journal of Hand Surgery , 43 (7), 678.e1-678.e9.  Full Text
    • Kamal, RN, Leversedge, F, Ruch, DS, Mithani, SK, Cotterell, IHF, & Richard, MJ. (2018, April 18). The Sigmoid Notch View for Distal Radius Fractures. The Journal of Hand Surgery ,.  Full Text
    • Koehler, SM, Matson, AP, & Mithani, SK. (2017, December). Application of a Modified Pedicled Adipofascial Lateral Arm Flap in the Prevention and Treatment of Radial Nerve Injuries. Techniques in Hand & Upper Extremity Surgery , 21 (4), 155-160.  Full Text
    • Shammas, RL, Hwang, BH, Levin, LS, Richard, MJ, Ruch, DS, & Mithani, SK. (2017, October). Outcomes of sympathectomy and vascular bypass for digital ischaemia in connective tissue disorders. The Journal of Hand Surgery, European Volume , 42 (8), 823-826.  Full Text
    • Avashia, YJ, Shammas, RL, Mithani, SK, & Parekh, SG. (2017, June). Soft Tissue Reconstruction After Total Ankle Arthroplasty. Foot and Ankle Clinics , 22 (2), 391-404. (Review)  Full Text
    • Dekker, TJ, Avashia, Y, Mithani, SK, Matson, AP, Lampley, AJ, & Adams, SB. (2017, February). Single-Stage Bipedicle Local Tissue Transfer and Skin Graft for Achilles Tendon Surgery Wound Complications. Foot & Ankle Specialist , 10 (1), 46-50.  Full Text
    • Giattino, CM, Gardner, JE, Sbahi, FM, Roberts, KC, Cooter, M, Moretti, E, Browndyke, JN, Mathew, JP, Woldorff, MG, Berger, M, & MADCO-PC Investigators, . (2017, January). Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults. Frontiers in systems neuroscience , 11 , 24-.  Full Text  Open Access Copy
    • Wooster, BM, Grimm, NL, DeOrio, JK, & Mithani, SK. (2017, January). Iatrogenic Arteriovenous Fistula With Associated Pseudoaneurysm of Posterior Tibial Artery After Revision Total Ankle Arthroplasty: A Case Report. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons , 56 (1), 75-77.  Full Text
    • Desai, MJ, Brogan, DM, Richard, MJ, Mithani, SK, Leversedge, FJ, & Ruch, DS. (2016, December). Biomechanical Comparison of Suture-Button Suspensionplasty and LRTI for Basilar Thumb Arthritis. Hand (New York, N.Y.) , 11 (4), 438-443.  Full Text
    • Cornejo, A, Neaman, KC, Srinivasan, RC, Mithani, SK, & Pederson, WC. (2016, June). In Situ Venous Bypass for Chronic Hand Ischemia: A Review of 25 Cases in 23 Patients. Annals of plastic surgery , 76 Suppl 4 , S275-S279.  Full Text
    • Desai, MJ, Mithani, SK, Lodha, SJ, Richard, MJ, Leversedge, FJ, & Ruch, DS. (2016, June). Major Peripheral Nerve Injuries After Elbow Arthroscopy. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association , 32 (6), 999-1002.e8.  Full Text
    • Richard, MJ, Lampley, A, Patel, P, Riikka, N, Mithani, S, Leversedge, FJ, & Ruch, DS. (2016). The Importance of the Palmar Lunate Facet in the Treatment of Distal Radius Fractures. The Duke Orthopaedic Journal , 6 (1), 56-60.
    • Ramalingam, S, Mithani, SK, Jong-Ryoon, B, & Ruch, DS. (2015, June). Closed median nerve rupture from elbow trauma. Hand (New York, N.Y.) , 10 (2), 346-348.  Full Text
    • Morwood, MP, Ruch, DS, Leversedge, FJ, Mithani, SK, Kamal, RN, & Richard, MJ. (2015, April). Olecranon fractures with sagittal splits treated with dual fixation. The Journal of hand surgery , 40 (4), 711-715.  Full Text
    • Manahan, MA, Buretta, KJ, Chang, D, Mithani, SK, Mallalieu, J, & Shermak, MA. (2015, March). An outcomes analysis of 2142 breast reduction procedures. Annals of plastic surgery , 74 (3), 289-292.  Full Text
    • Ruch, DS, Orr, SB, Richard, MJ, Leversedge, FJ, Mithani, SK, & Laino, DK. (2015, February). A comparison of débridement with and without anconeus muscle flap for treatment of refractory lateral epicondylitis. Journal of shoulder and elbow surgery , 24 (2), 236-241.  Full Text
    • Ruch, DS, Watters, TS, Wartinbee, DA, Richard, MJ, Leversedge, FJ, & Mithani, SK. (2014, August). Anatomic findings and complications after surgical treatment of chronic, partial distal biceps tendon tears: a case cohort comparison study. The Journal of Hand Surgery , 39 (8), 1572-1577.  Full Text
    • Mithani, SK, Srinivasan, RC, Kamal, R, Richard, MJ, Leversedge, FJ, & Ruch, DS. (2014, May). Salvage of distal radius nonunion with a dorsal spanning distraction plate. The Journal of hand surgery , 39 (5), 981-984. (Review)  Full Text
    • Brown, EN, Chaudhry, A, Mithani, SK, Bluebond-Langner, RO, Feiner, JM, Shaffer, CK, Call, D, & Rodriguez, ED. (2014, February). Long-term vascular, motor, and sensory donor site outcomes after ulnar forearm flap harvest. J Reconstr Microsurg , 30 (2), 115-120.  Full Text  Link to Item
    • Mundinger, GS, Dorafshar, AH, Gilson, MM, Mithani, SK, Kelamis, JA, Christy, MR, Manson, PN, & Rodriguez, ED. (2014, January). Analysis of radiographically confirmed blunt-mechanism facial fractures. J Craniofac Surg , 25 (1), 321-327.  Full Text  Link to Item
    • Mundinger, GS, Dorafshar, AH, Gilson, MM, Mithani, SK, Manson, PN, & Rodriguez, ED. (2013, December). Blunt-mechanism facial fracture patterns associated with internal carotid artery injuries: recommendations for additional screening criteria based on analysis of 4,398 patients. J Oral Maxillofac Surg , 71 (12), 2092-2100.  Full Text  Link to Item
    • Bellamy, JL, Mundinger, GS, Flores, JM, Reddy, SK, Mithani, SK, Rodriguez, ED, & Dorafshar, AH. (2013, November). Facial fractures of the upper craniofacial skeleton predict mortality and occult intracranial injury after blunt trauma: an analysis. J Craniofac Surg , 24 (6), 1922-1926.  Full Text  Link to Item
    • Srinivasan, RC, Jain, D, Richard, MJ, Leversedge, FJ, Mithani, SK, & Ruch, DS. (2013, June). Isolated ulnar shortening osteotomy for the treatment of extra-articular distal radius malunion. J Hand Surg Am , 38 (6), 1106-1110.  Full Text  Link to Item
    • Shermak, MA, Chang, D, Buretta, K, Mithani, S, Mallalieu, J, & Manahan, M. (2011, December). Increasing age impairs outcomes in breast reduction surgery. Plastic and Reconstructive Surgery , 128 (6), 1182-1187.  Full Text
    • Mithani, SK, Smith, IM, & Califano, JA. (2011, August). Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. Melanoma Research , 21 (4), 298-307.  Full Text
    • Mithani, SK, Davis, JM, & Rodriguez, ED. (2011). Use of 1-desamino-8-D-arginine vasopressin in microsurgical reconstruction in a patient with von Willebrand's disease. Microsurgery , 31 (2), 159-161.  Full Text
    • Chang, SS, Jiang, WW, Smith, I, Glazer, C, Sun, W-Y, Mithani, S, & Califano, JA. (2010). Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes. International Journal of Cancer , 126 (1), 19-27.  Full Text
    • Smith, IM, Mithani, SK, Mydlarz, WK, Chang, SS, & Califano, JA. (2010, January). Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. Orl; Journal for Oto Rhino Laryngology and Its Related Specialties , 72 (1), 44-50.  Full Text
    • Smith, IM, Mithani, SK, Liu, C, Chang, SS, Begum, S, Dhara, M, Westra, W, Sidranksy, D, & Califano, JA. (2009, May). Novel integrative methods for gene discovery associated with head and neck squamous cell carcinoma development. Archives of Otolaryngology Head & Neck Surgery , 135 (5), 487-495.  Full Text
    • Mithani, SK, Bluebond-Langner, R, & Rodriguez, ED. (2009). Expression microarray identifies novel markers of free flap failure in a rat model. Annals of Plastic Surgery , 63 (3), 323-326.  Full Text
    • Mithani, SK, Shao, C, Tan, M, Smith, IM, Califano, JA, El-Naggar, AK, & Ha, PK. (2009). Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS ONE , 4 (12).  Full Text  Open Access Copy
    • Mithani, SK, Shao, C, Tan, M, Smith, IM, Califano, JA, El-Naggar, AK, & Ha, PK. (2009). Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PloS one , 4 (12), e8493-.
    • Mithani, SK, St-Hilaire, H, Brooke, BS, Smith, IM, Bluebond-Langner, R, & Rodriguez, ED. (2009). Predictable patterns of intracranial and cervical spine injury in craniomaxillofacial trauma: Analysis of 4786 patients. Plastic and Reconstructive Surgery , 123 (4), 1293-1301.  Full Text
    • Smith, IM, Glazer, CA, Mithani, SK, Ochs, MF, Sun, W, Bhan, S, Vostrov, A, Abdullaev, Z, Lobanenkov, V, Gray, A, Liu, C, Chang, SS, Ostrow, KL, Westra, WH, Begum, S, Dhara, M, & Califano, J. (2009, January). Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer. Plos One , 4 (3), e4961-null.  Full Text  Open Access Copy
    • St-Hilaire, H, Mithani, SK, & Rodriguez, ED. (2009). Microsurgical salvage of the intractable oral vestibule. Plastic and Reconstructive Surgery , 123 (1), 331-338.  Full Text
    • Mithani, SK, Smith, IM, Topalian, SL, & Califano, JA. (2008, June). Nonsynonymous somatic mitochondrial mutations occur in the majority of cutaneous melanomas. Melanoma Research , 18 (3), 214-219.  Full Text
    • Bluebond-Langner, R, Keifa, ES, Mithani, S, Bochicchio, GV, Scalea, T, & Rodriguez, ED. (2008). Recurrent abdominal laxity following interpositional human acellular dermal matrix. Annals of Plastic Surgery , 60 (1), 76-80.  Full Text
    • Mithani, SK, Smith, IM, Zhou, S, Gray, A, Koch, WM, Maitra, A, & Califano, JA. (2007, December). Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research , 13 (24), 7335-7340.  Full Text
    • Zhou, S, Kachhap, S, Sun, W, Wu, G, Chuang, A, Poeta, L, Grumbine, L, Mithani, SK, Chatterjee, A, Koch, W, Westra, WH, Maitra, A, Glazer, C, Carducci, M, Sidransky, D, McFate, T, Verma, A, & Califano, JA. (2007, May). Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proceedings of the National Academy of Sciences of the United States of America , 104 (18), 7540-7545.  Full Text
    • Mithani, SK, Mydlarz, WK, Grumbine, FL, Smith, IM, & Califano, JA. (2007, March). Molecular genetics of premalignant oral lesions. Oral Diseases , 13 (2), 126-133. (Review)  Full Text
    • Mithani, SK, Taube, JM, Zhou, S, Smith, IM, Koch, WM, Westra, WH, & Califano, JA. (2007). Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer. Clinical Cancer Research , 13 (15), 4331-4335.  Full Text
    • Smith, IM, Mydlarz, WK, Mithani, SK, & Califano, JA. (2007). DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. International Journal of Cancer , 121 (8), 1724-1728.  Full Text
    • Mithani, SK, & Tufaro, AP. (2006). Management of wound complications in spinal surgery. Neurosurgery Quarterly , 16 (1), 9-14.  Full Text
    • Mithani, SK, Marohn, MR, Freischlag, JA, Dackiw, APB, & Zeiger, MA. (2006). Laparoscopic resection of a paraganglioma of the organ of Zuckerkandl in a patient with a carotid body tumor. American Surgeon , 72 (1), 55-59.
    • Balch, GC, Mithani, SK, Simpson, JF, & Kelley, MC. (2005, January). Accuracy of intraoperative gross examination of surgical margin status in women undergoing partial mastectomy for breast malignancy. The American Surgeon , 71 (1), 22-27.
    • Mithani, SK, Balch, GC, Shiou, S-R, Whitehead, RH, Datta, PK, & Beauchamp, RD. (2004, April). Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells. The Journal of Surgical Research , 117 (2), 296-305.  Full Text
    • Parker, MA, Deane, NG, Thompson, EA, Whitehead, RH, Mithani, SK, Washington, MK, Datta, PK, Dixon, DA, & Beauchamp, RD. (2003, December). Over-expression of cyclin D1 regulates Cdk4 protein synthesis. Cell Proliferation , 36 (6), 347-360.  Full Text
    • Balch, GC, Mithani, SK, Richards, KR, Beauchamp, RD, & Kelley, MC. (2003). Lymphatic mapping and sentinel lymphadenectomy after preoperative therapy for stage II and III breast cancer. Annals of Surgical Oncology , 10 (6), 616-621.  Full Text

  • Other Articles

    • Mithani, SK, Kelamis, JA, Gerhard, MS, Brooke, BS, Smith, IM, Bluebond-Langner, R, & Rodriguez, E. (2012). The prevalence of cervical spine injury, head injury, or both with isolated and multiple craniomaxillofacial fractures. Plastic and Reconstructive Surgery , 129 (1), 163e-.  Full Text
    • St-Hilaire, H, Mithani, SK, Taylor, J, Simmons, OP, Singh, N, & Rodriguez, ED. (2009). Restoring the failed cranioplasty: Nonanatomical titanium mesh with perforator flap. Plastic and Reconstructive Surgery , 123 (6), 1813-1817.  Full Text
    • Grandis, JR, Califano, J, Smith, I, & Mithani, S. (2007). Response: Re: Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis [2]. Journal of the National Cancer Institute , 99 (17), 1344--.  Full Text
    • Rodriguez, ED, Mithani, SK, Bluebond-Langner, R, & Manson, PN. (2007). Hand evaluation following ulnar forearm perforator flap harvest: A prospective study. Plastic and Reconstructive Surgery , 120 (6), 1598-1601.  Full Text
    • Balch, GC, Mithani, SK, Richards, KR, & Breslin, TM. (2004). Lymphatic mapping and sentinel lymphadenectomy after preoperative therapy for stage II and III breast cancer. Breast Diseases , 15 (1), 65--.

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