Susan Kay Murphy
Associate Professor in Obstetrics and Gynecology
Current Research Interests
- ovarian cancer epigenetics
- therapeutic prevention of ovarian cancer recurrence
- development of epigenetic screening tools
- developmental origins of health and disease (DOHaD)
- preconceptional environmental impact on the epigenome
- intergenerational and transgenerational epigenetic effects
- in vitro models of cellular differentiation
Current Appointments & Affiliations
- Associate Professor in Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Sciences, Obstetrics and Gynecology 2014
- Chief, Division of Reproductive Sciences in the Department of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Sciences, Obstetrics and Gynecology 2017
- Associate Professor in Pathology, Pathology, Clinical Science Departments 2012
- Associate Professor in the Division of Environmental Science and Policy, Environmental Sciences and Policy, Nicholas School of the Environment 2017
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1998
Contact Information
- 701 W. Main Street, Suite 510, Room 5140; Duke PO Box 90534, Durham, NC 27701
- Duke PO Box 90534, The Chesterfield Building, Durham, NC 27701
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susan.murphy@duke.edu
(919) 681-3423
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CIPHERS Project
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Murphy lab web site
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NICHES Children's Environmental Health Center
- Background
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Education, Training, & Certifications
- Ph.D., Wake Forest University 1998
- B.A., University of North Carolina - Charlotte 1992
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Previous Appointments & Affiliations
- Associate Professor in Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology, Obstetrics and Gynecology 2012 - 2014
- Assistant Professor in Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology, Obstetrics and Gynecology 2008 - 2012
- Assistant Professor in Pathology, Pathology, Clinical Science Departments 2008 - 2012
- Assistant Professor in Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology, Obstetrics and Gynecology 2006 - 2007
- Assistant Research Professor in Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology, Obstetrics and Gynecology 2003 - 2006
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Leadership & Clinical Positions at Duke
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2020 Chair, ITEHP Admissions Committee
2017 Division Chief, Reproductive Sciences, Department of Obstetrics and Gynecology
2016 Program Director, CIPHERS study of the impact of cannabis on the sperm epigenome
2014-2015 Director, Duke Epigenetics and Epigenomics Program
2013 Program Director, NICHES Children's Environmental Health and Disease Prevention Research Center
2012-2014 Co-Director, Duke Epigenetics and Epigenomics Program
2011- Founder and Executive Committee Member, Duke Epigenetic and Epigenomics Program
2003 Director, Epigenetics Research Laboratory
2002-2003 Founder and Director, Mentorship Program, Duke University Postdoctoral Association
2001-2003 Advocacy Chair, Duke University Postdoctoral Association
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2020 Chair, ITEHP Admissions Committee
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Academic Positions Outside Duke
- Thesis Advisor, University of Minnesota. 2019 - 2022
- Recognition
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In the News
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NOV 28, 2022 -
SEP 23, 2021 Duke Health News -
AUG 27, 2019 Duke Health News -
DEC 6, 2013 Duke Today -
SEP 23, 2013 NPR
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Awards & Honors
- Outstanding Senior Scientist. The Campion Fund. April 6, 2018
- Distinguished Nominee, Gordon G. Hammes Faculty Teaching Award. Duke School of Medicine. 2018
- Selected to deliver GradX keynote. Duke Graduate Student Association. 2018
- Paper Selected as Editor's Choice. American Chemical Society. 2017
- Paper of the Year. Environmental Health Perspectives. 2014
- Best Poster. Duke Comprehensive Cancer Center. 2006
- Membership. Omicron Delta Kappa Leadership Honor Society. 1991
- Outstanding Senior. UNC Charlotte, Charlotte, NC. 1991
- Research Presentation Award. North Carolina Academy of Science. 1991
- Member. Golden Key National Honor Society. 1990
- Member. Honor Society of Phi Kappa Phi. 1990
- Undergraduate Research Award. Sigma Xi. 1990
- Member. Beta Beta Beta Biological Honor Society. 1989
- Expertise
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Subject Headings
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Global Scholarship
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Research
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Teaching
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- Research
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Selected Grants
- Building Interdisciplinary Research Careers in Women's Health awarded by National Institutes of Health 2002 - 2027
- Population Health Research Support IDIQ Base awarded by National Institutes of Health 2018 - 2025
- Duke Women's Reproductive Health Research Scholars awarded by National Institutes of Health 2020 - 2025
- Pharmacological Sciences Training Grant awarded by National Institutes of Health 2020 - 2025
- The role of ferroptosis in the metastatic ovarian cancer awarded by Ovarian Cancer Research Alliance 2022 - 2024
- Duke University Program in Environmental Health awarded by National Institutes of Health 2019 - 2024
- The Southeastern Liver Health Cohort Study awarded by North Carolina State University 2021 - 2023
- Does exposure to mitochondrial toxicants during germ cell development result in lifelong alterations in mitochondrial function mediated by epigenetic changes? awarded by National Institutes of Health 2017 - 2023
- Duke KURe Program awarded by National Institutes of Health 2013 - 2023
- Follow-up and Maintenance of the Newborn Epigenetics STudy (NEST) Cohort awarded by North Carolina State University 2018 - 2023
- Role of Age-Related Changes in the Tumor Microenvironment on Ovarian Cancer Progression awarded by National Institutes of Health 2021 - 2023
- Population Health Research Support - Study of Pregnancy and Neonatal Health (SPAN) Task A awarded by National Institutes of Health 2019 - 2023
- Translational Research in Surgical Oncology awarded by National Institutes of Health 2002 - 2022
- Paternal Transgenerational Epigenetic Legacy from Use of Cannabis awarded by John Templeton Foundation 2017 - 2022
- Social adversities, epigenetics, and the obesity epidemic awarded by North Carolina State University 2017 - 2022
- Validation and interrogation of differentially expressed and alternatively spliced genes in African American prostate cancer awarded by Department of Defense 2014 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Pharmacological Sciences Training Program awarded by National Institutes of Health 1975 - 2020
- Children Exposure to SVOC Mixtures Indoors and Associations with Obesity awarded by National Institutes of Health 2017 - 2020
- Epigenomics in insulin resistance associated overactive bladder awarded by National Institutes of Health 2017 - 2020
- Genetic and Epigenetic Markers of Progressive Nonalcoholic Fatty Liver Disease awarded by American Association for the Study of Liver Diseases 2018 - 2020
- Epigenetics and the Development of Nonalcoholic Fatty Liver Disease awarded by American College of Gastroenterology 2015 - 2019
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2019
- Neurodevelopment and Improving Children's Health Following EtS Exposure (NICHES) awarded by National Institutes of Health 2013 - 2019
- Neurodevelopment and Improving Children's Health following EtS exposure (NICHES) awarded by Environmental Protection Agency 2013 - 2019
- Triggering human anti-tumor stringent response to target recurrent ovarian cancer awarded by Department of Defense 2017 - 2019
- Immune regulated amino acid pathways in Alzheimer's Disease awarded by National Institutes of Health 2016 - 2018
- Pilot Project: Effects of Cannabis on the Epigenome of Humans and Rats awarded by John Templeton Foundation 2016 - 2017
- Joint Environmental, Genetic and Epigenetic Regulation of Tyrosine Receptor Kinases and Childhood Respiratory Disease awarded by University of Southern California 2013 - 2017
- Functional Genomic Screens of Tumor Recurrence in Ovarian Cancer awarded by Department of Defense 2014 - 2017
- Cancer Biology Training Grant awarded by National Cancer Institute 1993 - 2016
- Obesity and deregulation of imprinted genes in early life awarded by National Institutes of Health 2010 - 2015
- Epigenetic influence on the early childhood self-regulation capacities and obesity awarded by National Institutes of Health 2011 - 2014
- Ovarian Cancer Initiating Cells: Metabolic Characterization awarded by National Institutes of Health 2012 - 2014
- Gene Regulation in Recurrent Ovarian Cancers awarded by Gynecologic Cancer Foundation 2011 - 2014
- Disparities in cervical cancer precursors and deregulation of imprinted genes awarded by National Institutes of Health 2010 - 2014
- Nutrition, Deregulation of Imprinted Genes and Rapid Weight Gain in Early Life awarded by National Institutes of Health 2009 - 2014
- Characterizing Alcohol's Effects on Repair of Liver Injury awarded by National Institutes of Health 2009 - 2012
- Identification and Characterization of Epigenetically Labile Genes awarded by National Institutes of Health 2006 - 2010
- In-utero Exposure and Infant Loss of IGF2 Imprinting awarded by National Institutes of Health 2006 - 2008
- Imprinted PEG3 Domain at 19q13.4 and carcinogenesis awarded by National Institutes of Health 2001 - 2003
- missing activity
- missing activity
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External Relationships
- Apple Inc.
- Society of Reproductive Investigation
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Fuemmeler BF, Glasgow TE, Schechter JC, Maguire R, Sheng Y, Bidopia T, et al. Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/Hyperactivity Disorder. J Pediatr. 2023 May;256:77-84.e1.Full Text Link to Item
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Sosnowski DW, Ellison-Barnes A, Kaufman J, Hoyo C, Murphy SK, Hernandez RG, et al. Financial stress as a mediator of the association between maternal childhood adversity and infant birth weight, gestational age, and NICU admission. Bmc Public Health. 2023 Mar 30;23(1):606.Full Text Link to Item
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Hedges JC, Hanna CB, Shorey-Kendrick LE, Boniface ER, Bash JC, Rice-Stitt TL, et al. Cessation of chronic delta-9-tetrahydrocannabinol use partially reverses impacts on male fertility and the sperm epigenome in rhesus macaques. Fertil Steril. 2023 Mar 24;Full Text Link to Item
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Correction to: Tobacco Retail Outlets, Neighborhood Deprivation and the Risk of Prenatal Smoke Exposure. Nicotine Tob Res. 2023 Mar 22;25(4):846.Full Text Link to Item
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Crute CE, Landon CD, Garner A, Hall SM, Everitt JI, Zhang S, et al. Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits. Toxicol Sci. 2023 Feb 17;191(2):239–52.Full Text Link to Item
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Ceasrine AM, Devlin BA, Bolton JL, Green LA, Jo YC, Huynh C, et al. Maternal diet disrupts the placenta-brain axis in a sex-specific manner. Nat Metab. 2022 Dec;4(12):1732–45.Full Text Link to Item
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King DE, Sparling AC, Lloyd D, Satusky MJ, Martinez M, Grenier C, et al. Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes. Epigenetics. 2022 Dec;17(12):1573–89.Full Text Link to Item
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Wheeler DC, Boyle J, Jeremy Barsell D, Maguire RL, Zhang JJ, Oliver JA, et al. Tobacco Retail Outlets, Neighborhood Deprivation and the Risk of Prenatal Smoke Exposure. Nicotine Tob Res. 2022 Nov 12;24(12):2003–10.Full Text Link to Item
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Gonzalez-Nahm S, Marchesoni J, Maity A, Maguire RL, House JS, Tucker R, et al. Maternal Mediterranean Diet Adherence and Its Associations with Maternal Prenatal Stressors and Child Growth. Curr Dev Nutr. 2022 Nov;6(11):nzac146.Full Text Link to Item
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Moylan CA, Mavis AM, Jima D, Maguire R, Bashir M, Hyun J, et al. Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children. Epigenetics. 2022 Nov;17(11):1446–61.Full Text Link to Item
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Wheeler DC, Boyle J, Barsell DJ, Maguire RL, Dahman B, Murphy SK, et al. Neighborhood Deprivation is Associated with Increased Risk of Prenatal Smoke Exposure. Prev Sci. 2022 Oct;23(7):1078–89.Full Text Link to Item
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Crute CE, Hall SM, Landon CD, Garner A, Everitt JI, Zhang S, et al. Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model. Sci Total Environ. 2022 Sep 10;838(Pt 4):156499.Full Text Link to Item
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Schrott R, Modliszewski JL, Hawkey AB, Grenier C, Holloway Z, Evans J, et al. Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring. Epigenetics Chromatin. 2022 Sep 10;15(1):33.Full Text Open Access Copy Link to Item
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Lloyd DT, Skinner HG, Maguire R, Murphy SK, Motsinger-Reif AA, Hoyo C, et al. Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions. Int J Mol Sci. 2022 Sep 9;23(18).Full Text Link to Item
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Bukowski A, Hoyo C, Hudgens MG, Brewster WR, Valea F, Bentley RC, et al. Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States. Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1564–71.Full Text Link to Item
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Miller CA, Jung Kim S, Schwartz-Bloom RD, Bloom PN, Murphy SK, Fuemmeler BF. Informing women about the risks of exposing babies to tobacco smoke: outreach and education efforts using Facebook "boost posts". Transl Behav Med. 2022 May 26;12(5):714–20.Full Text Link to Item
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Joglekar R, Cauley M, Lipsich T, Corcoran DL, Patisaul HB, Levin ED, et al. Developmental nicotine exposure and masculinization of the rat preoptic area. Neurotoxicology. 2022 Mar;89:41–54.Full Text Link to Item
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Crute C, Liao Y, Son E, Grenier C, Huang Z, Hoyo C, et al. Validation of differential DNA methylation in newborns exposed to tobacco smoke during gestation using bisulfite pyrosequencing. Micropubl Biol. 2022;2022.Full Text Link to Item
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Joglekar R, Grenier C, Hoyo C, Hoffman K, Murphy SK. Maternal tobacco smoke exposure is associated with increased DNA methylation at human metastable epialleles in infant cord blood. Environ Epigenet. 2022;8(1):dvac005.Full Text Link to Item
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Schrott R, Greeson KW, King D, Symosko Crow KM, Easley CA, Murphy SK. Cannabis alters DNA methylation at maternally imprinted and autism candidate genes in spermatogenic cells. Syst Biol Reprod Med. 2022;68(5–6):357–69.Full Text Link to Item
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Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, et al. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 2022;789:108415.Full Text Link to Item
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Vidal AC, Moylan CA, Wilder J, Grant DJ, Murphy SK, Hoyo C. Racial disparities in liver cancer: Evidence for a role of environmental contaminants and the epigenome. Front Oncol. 2022;12:959852.Full Text Link to Item
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Holloway Z, Hawkey AB, Pippen E, White H, Katragadda V, Kenou B, et al. Corrigendum to "Paternal cannabis extract exposure in rats: Preconception timing effects on neurobehavioral effects in offspring" [Neurotoxicology 81 (2020) 180-188]. Neurotoxicology. 2021 Dec;87:258.Full Text Link to Item
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Alick CL, Maguire RL, Murphy SK, Fuemmeler BF, Hoyo C, House JS. Periconceptional Maternal Diet Characterized by High Glycemic Loading Is Associated with Offspring Behavior in NEST. Nutrients. 2021 Sep 13;13(9).Full Text Link to Item
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Monangi N, Xu H, Khanam R, Khan W, Deb S, Pervin J, et al. Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis. Bmj Glob Health. 2021 Sep;6(9).Full Text Link to Item
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Maguire RL, House JS, Lloyd DT, Skinner HG, Allen TK, Raffi AM, et al. Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort. Pediatr Obes. 2021 Jul;16(7):e12763.Full Text Link to Item
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Bosire C, Vidal AC, Smith JS, Jima D, Huang Z, Skaar D, et al. Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia. Infect Agent Cancer. 2021 Jun 13;16(1):42.Full Text Open Access Copy Link to Item
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Ksinan AJ, Sheng Y, Do EK, Schechter JC, Zhang JJ, Maguire RL, et al. Identifying the Best Questions for Rapid Screening of Secondhand Smoke Exposure Among Children. Nicotine Tob Res. 2021 Jun 8;23(7):1217–23.Full Text Link to Item
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Fallavollita WL, Do EK, Schechter JC, Kollins SH, Zheng JJ, Qin J, et al. Smoke-Free Home Rules and Association with Child Secondhand Smoke Exposure among Mother-Child Dyad Relationships. Int J Environ Res Public Health. 2021 May 14;18(10).Full Text Link to Item
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Fuemmeler BF, Dozmorov MG, Do EK, Zhang JJ, Grenier C, Huang Z, et al. DNA Methylation in Babies Born to Nonsmoking Mothers Exposed to Secondhand Smoke during Pregnancy: An Epigenome-Wide Association Study. Environ Health Perspect. 2021 May;129(5):57010.Full Text Open Access Copy Link to Item
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Keyhan S, Burke E, Schrott R, Huang Z, Grenier C, Price T, et al. Male obesity impacts DNA methylation reprogramming in sperm. Clin Epigenetics. 2021 Jan 25;13(1):17.Full Text Open Access Copy Link to Item
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Gu J, Barrera J, Yun Y, Murphy SK, Beach TG, Woltjer RL, et al. Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains. Front Neurosci. 2021;15:652226.Full Text Link to Item
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Huang Z, Kondoh E, Visco ZR, Baba T, Matsumura N, Dolan E, et al. Targeting Dormant Ovarian Cancer Cells In Vitro and in an In Vivo Mouse Model of Platinum Resistance. Mol Cancer Ther. 2021 Jan;20(1):85–95.Full Text Link to Item
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King DE, Sparling AC, Joglekar R, Meyer JN, Murphy SK. Direct comparisons of bisulfite pyrosequencing versus targeted bisulfite sequencing. Micropubl Biol. 2021;2021.Full Text Open Access Copy Link to Item
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Schrott R, Murphy SK, Modliszewski JL, King DE, Hill B, Itchon-Ramos N, et al. Refraining from use diminishes cannabis-associated epigenetic changes in human sperm. Environ Epigenet. 2021;7(1):dvab009.Full Text Link to Item
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Soubry A, Murphy SK, Vansant G, He Y, Price TM, Hoyo C. Opposing Epigenetic Signatures in Human Sperm by Intake of Fast Food Versus Healthy Food. Front Endocrinol (Lausanne). 2021;12:625204.Full Text Link to Item
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Visco ZR, Sfakianos G, Grenier C, Boudreau M-H, Simpson S, Rodriguez I, et al. Epigenetic Regulation of Claudin-1 in the Development of Ovarian Cancer Recurrence and Drug Resistance. Front Oncol. 2021;11:620873.Full Text Link to Item
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Acharya KS, Schrott R, Grenier C, Huang Z, Holloway Z, Hawkey A, et al. Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC). Scientific Reports. 2020 Dec 1;10(1).Full Text
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Holloway ZR, Hawkey AB, Torres AK, Evans J, Pippen E, White H, et al. Paternal cannabis extract exposure in rats: Preconception timing effects on neurodevelopmental behavior in offspring. Neurotoxicology. 2020 Dec;81:180–8.Full Text Link to Item
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Vehmeijer FOL, Küpers LK, Sharp GC, Salas LA, Lent S, Jima DD, et al. DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies. Genome Med. 2020 Nov 25;12(1):105.Full Text Link to Item
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Neumann A, Walton E, Alemany S, Cecil C, González JR, Jima DD, et al. Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis. Transl Psychiatry. 2020 Nov 12;10(1):398.Full Text Link to Item
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York TP, Latendresse SJ, Jackson-Cook C, Lapato DM, Moyer S, Wolen AR, et al. Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth. Epigenetics. 2020 Nov;15(11):1243–58.Full Text Link to Item
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Schrott R, Rajavel M, Acharya K, Huang Z, Acharya C, Hawkey A, et al. Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin. Sci Rep. 2020 Sep 29;10(1):16022.Full Text Link to Item
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Acharya KS, Schrott R, Grenier C, Huang Z, Holloway Z, Hawkey A, et al. Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC). Sci Rep. 2020 Jul 23;10(1):12251.Full Text Open Access Copy Link to Item
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Fuemmeler BF, Sheng Y, Schechter JC, Do E, Zucker N, Majors A, et al. Associations between attention deficit hyperactivity disorder symptoms and eating behaviors in early childhood. Pediatr Obes. 2020 Jul;15(7):e12631.Full Text Link to Item
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Holloway ZR, Hawkey AB, Pippin E, White H, Wells C, Kenou B, et al. Paternal factors in neurodevelopmental toxicology: THC exposure of male rats causes long-lasting neurobehavioral effects in their offspring. Neurotoxicology. 2020 May;78:57–63.Full Text Link to Item
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Schechter J, Do EK, Zhang JJ, Hoyo C, Murphy SK, Kollins SH, et al. Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms. Nicotine Tob Res. 2020 Jan 27;22(1):40–7.Full Text Open Access Copy Link to Item
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Schrott R, Acharya K, Itchon-Ramos N, Hawkey AB, Pippen E, Mitchell JT, et al. Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm. Epigenetics. 2020;15(1–2):161–73.Full Text Link to Item
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Schrott R, Murphy SK. Cannabis use and the sperm epigenome: a budding concern? Environ Epigenet. 2020 Jan;6(1):dvaa002.Full Text Open Access Copy Link to Item
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Yang W-H, Huang Z, Wu J, Ding C-KC, Murphy SK, Chi J-T. A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer. Mol Cancer Res. 2020 Jan;18(1):79–90.Full Text Link to Item
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Xue H, Maguire RL, Liu J, Kollins SH, Murphy SK, Hoyo C, et al. Snacking frequency and dietary intake in toddlers and preschool children. Appetite. 2019 Nov 1;142:104369.Full Text Link to Item
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Yamanoi K, Baba T, Abiko K, Hamanishi J, Yamaguchi K, Murakami R, et al. Acquisition of a side population fraction augments malignant phenotype in ovarian cancer. Sci Rep. 2019 Oct 2;9(1):14215.Full Text Link to Item
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Sikdar S, Joehanes R, Joubert BR, Xu C-J, Vives-Usano M, Rezwan FI, et al. Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics. 2019 Oct;11(13):1487–500.Full Text Link to Item
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Hansen LJ, Sun R, Yang R, Singh SX, Chen LH, Pirozzi CJ, et al. MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation. Cancer Res. 2019 Jul 1;79(13):3383–94.Full Text Link to Item
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House JS, Hall J, Park SS, Planchart A, Money E, Maguire RL, et al. Cadmium exposure and MEG3 methylation differences between Whites and African Americans in the NEST Cohort. Environ Epigenet. 2019 Jul;5(3):dvz014.Full Text Link to Item
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Meekins AR, Murphy SK, Grenier C, Huang Z, Bradley MS, Amundsen CL, et al. Role of β-3 adrenergic receptor polymorphism in overactive bladder. Neurourol Urodyn. 2019 Jun;38(5):1261–5.Full Text Link to Item
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Reese SE, Xu C-J, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, et al. Epigenome-wide meta-analysis of DNA methylation and childhood asthma. J Allergy Clin Immunol. 2019 Jun;143(6):2062–74.Full Text Link to Item
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Chawla D, Fuemmeler B, Benjamin-Neelon SE, Hoyo C, Murphy S, Daniels JL. Early prenatal vitamin D concentrations and social-emotional development in infants. J Matern Fetal Neonatal Med. 2019 May;32(9):1441–8.Full Text Link to Item
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Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, et al. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nat Commun. 2019 Apr 23;10(1):1893.Full Text Link to Item
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Martin CL, Jima D, Sharp GC, McCullough LE, Park SS, Gowdy KM, et al. Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study. Epigenetics. 2019 Apr;14(4):325–40.Full Text Link to Item
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Tagliafierro L, Ilich E, Moncalvo M, Gu J, Sriskanda A, Grenier C, et al. Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models. J Vis Exp. 2019 Mar 29;(145).Full Text Link to Item
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Fuemmeler BF, Zucker N, Sheng Y, Sanchez CE, Maguire R, Murphy SK, et al. Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children. Int J Environ Res Public Health. 2019 Feb 25;16(4).Full Text Open Access Copy Link to Item
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Do EK, Zucker NL, Huang ZY, Schechter JC, Kollins SH, Maguire RL, et al. Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children. Pediatr Obes. 2019 Feb;14(2):e12454.Full Text Link to Item
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Bradley MS, Boudreau M-H, Grenier C, Huang Z, Murphy SK, Siddiqui NY. Urine RNA Processing in a Clinical Setting: Comparison of 3 Protocols. Female Pelvic Med Reconstr Surg. 2019;25(3):247–51.Full Text Link to Item
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Brown P, RELISH Consortium, Zhou Y. Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database (Oxford). 2019 Jan 1;2019.Full Text Link to Item
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Hawkey AB, White H, Pippen E, Greengrove E, Rezvani AH, Murphy SK, et al. Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring. Neurotoxicol Teratol. 2019;74:106808.Full Text Open Access Copy Link to Item
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Levin ED, Hawkey AB, Hall BJ, Cauley M, Slade S, Yazdani E, et al. Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring. Neurotoxicol Teratol. 2019;74:106806.Full Text Link to Item
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Sorrow P, Maguire R, Murphy SK, Belcher SM, Hoyo C. Elevated metabolites of acetaminophen in cord blood of children with obesity. Pediatr Obes. 2019 Jan;14(1).Full Text Link to Item
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Kantor B, Tagliafierro L, Gu J, Zamora ME, Ilich E, Grenier C, et al. Downregulation of SNCA Expression by Targeted Editing of DNA Methylation: A Potential Strategy for Precision Therapy in PD. Mol Ther. 2018 Nov 7;26(11):2638–49.Full Text Link to Item
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Gomih A, Smith JS, North KE, Hudgens MG, Brewster WR, Huang Z, et al. DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions. Int J Cancer. 2018 Aug 1;143(3):552–60.Full Text Link to Item
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Gao L, Liu X, Millstein J, Siegmund KD, Dubeau L, Maguire RL, et al. Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. Clin Epigenetics. 2018 Jul 20;10(1):98.Full Text Link to Item
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Green AJ, Hoyo C, Mattingly CJ, Luo Y, Tzeng J-Y, Murphy SK, et al. Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study. Int J Obes (Lond). 2018 Jul;42(7):1285–95.Full Text Link to Item
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Tindula G, Murphy SK, Grenier C, Huang Z, Huen K, Escudero-Fung M, et al. DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure. Epigenomics. 2018 Jul;10(7):1011–26.Full Text Link to Item
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Dozmorov MG, Bilbo SD, Kollins SH, Zucker N, Do EK, Schechter JC, et al. Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning. Brain Behav Immun. 2018 May;70:390–7.Full Text Link to Item
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Benjamin Neelon SE, White AJ, Vidal AC, Schildkraut JM, Murtha AP, Murphy SK, et al. Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years. Int J Obes (Lond). 2018 Apr;42(4):587–93.Full Text Link to Item
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Schrott R, Murphy SK. Folic acid throughout pregnancy: too much? Am J Clin Nutr. 2018 Apr 1;107(4):497–8.Full Text Link to Item
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Bradley MS, Burke EE, Grenier C, Amundsen CL, Murphy SK, Siddiqui NY. A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome. Neurourol Urodyn. 2018 Apr;37(4):1485–93.Full Text Link to Item
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Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, et al. Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol. 2018 Feb 1;47(1):22-23u.Full Text Link to Item
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Schechter JC, Fuemmeler BF, Hoyo C, Murphy SK, Zhang JJ, Kollins SH. Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States. Int J Environ Res Public Health. 2018 Jan 6;15(1).Full Text Link to Item
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Gonzalez-Nahm S, Mendez MA, Benjamin-Neelon SE, Murphy SK, Hogan VK, Rowley DL, et al. DNA methylation of imprinted genes at birth is associated with child weight status at birth, 1 year, and 3 years. Clin Epigenetics. 2018;10:90.Full Text Link to Item
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House JS, Mendez M, Maguire RL, Gonzalez-Nahm S, Huang Z, Daniels J, et al. Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes. Front Cell Dev Biol. 2018;6:107.Full Text Link to Item
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Murphy SK, Itchon-Ramos N, Visco Z, Huang Z, Grenier C, Schrott R, et al. Cannabinoid exposure and altered DNA methylation in rat and human sperm. Epigenetics. 2018;13(12):1208–21.Full Text Open Access Copy Link to Item
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Wegermann K, Henao R, Diehl AM, Murphy SK, Abdelmalek MF, Moylan CA. Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study. Plos One. 2018;13(9):e0204308.Full Text Link to Item
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Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, et al. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Human Molecular Genetics. 2017 Oct;26(20):4067–85.Full Text Open Access Copy
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Cordero FJ, Huang Z, Grenier C, He X, Hu G, McLendon RE, et al. Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG. Mol Cancer Res. 2017 Sep;15(9):1243–54.Full Text Link to Item
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Liu Y, Reynolds LM, Ding J, Hou L, Lohman K, Young T, et al. Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis. Nat Commun. 2017 Aug 30;8(1):393.Full Text Link to Item
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McCullough LE, Miller EE, Calderwood LE, Shivappa N, Steck SE, Forman MR, et al. Maternal inflammatory diet and adverse pregnancy outcomes: Circulating cytokines and genomic imprinting as potential regulators? Epigenetics. 2017 Aug;12(8):688–97.Full Text Link to Item
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Gonzalez-Nahm S, Mendez M, Robinson W, Murphy SK, Hoyo C, Hogan V, et al. Low maternal adherence to a Mediterranean diet is associated with increase in methylation at the MEG3-IG differentially methylated region in female infants. Environ Epigenet. 2017 May;3(2):dvx007.Full Text Link to Item
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Luo Y, McCullough LE, Tzeng J-Y, Darrah T, Vengosh A, Maguire RL, et al. Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight. Bmc Public Health. 2017 Apr 24;17(1):354.Full Text Open Access Copy Link to Item
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Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, et al. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environ Health Perspect. 2017 Apr;125(4):511–26.Full Text Link to Item
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Hoffman K, Butt CM, Webster TF, Preston EV, Hammel SC, Makey C, et al. Temporal Trends in Exposure to Organophosphate Flame Retardants in the United States. Environ Sci Technol Lett. 2017 Mar 14;4(3):112–8.Full Text Link to Item
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Mwinyi J, Boström AE, Pisanu C, Murphy SK, Erhart W, Schafmayer C, et al. NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar;1862(3):314–23.Full Text Link to Item
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Gao L, Millstein J, Siegmund KD, Dubeau L, Maguire R, Gilliland FD, et al. Epigenetic regulation of AXL and risk of childhood asthma symptoms. Clin Epigenetics. 2017;9:121.Full Text Link to Item
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Maguire RL, Vidal AC, Murphy SK, Hoyo C. Disparities in Cervical Cancer Incidence and Mortality: Can Epigenetics Contribute to Eliminating Disparities? Adv Cancer Res. 2017;133:129–56.Full Text Link to Item
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Soubry A, Hoyo C, Butt CM, Fieuws S, Price TM, Murphy SK, et al. Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm. Environ Epigenet. 2017 Jan;3(1):dvx003.Full Text Link to Item
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Yamanoi K, Matsumura N, Murphy SK, Baba T, Abiko K, Hamanishi J, et al. Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer. Oncotarget. 2016 Jul 26;7(30):47620–36.Full Text Link to Item
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Schiöth HB, Boström A, Murphy SK, Erhart W, Hampe J, Moylan C, et al. A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease. Bmc Genomics. 2016 Jun 14;17:462.Full Text Link to Item
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Fuemmeler BF, Wang L, Iversen ES, Maguire R, Murphy SK, Hoyo C. Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort. Child Obes. 2016 Jun;12(3):210–8.Full Text Link to Item
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Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, et al. Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. Environ Health Perspect. 2016 May;124(5):666–73.Full Text Link to Item
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Dewi FN, Wood CE, Willson CJ, Register TC, Lees CJ, Howard TD, et al. Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. Cancer Prev Res (Phila). 2016 May;9(5):385–95.Full Text Link to Item
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Murakami R, Matsumura N, Mandai M, Yoshihara K, Tanabe H, Nakai H, et al. Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes. Am J Pathol. 2016 May;186(5):1103–13.Full Text Link to Item
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Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, et al. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. Am J Hum Genet. 2016 Apr 7;98(4):680–96.Full Text Link to Item
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Peng J, Yoshioka Y, Mandai M, Matsumura N, Baba T, Yamaguchi K, et al. The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target. Mol Carcinog. 2016 Apr;55(4):335–45.Full Text Link to Item
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Matsumura N, Yamanoi K, Murphy SK, Hamanishi J, Abiko K, Yamaguchi K, et al. Abstract A38: Identification through functional genomics screening of factors whose downregulation enhances the side population in ovarian cancer. Clinical Cancer Research. 2016 Jan 15;22(2_Supplement):A38–A38.Full Text
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Fuemmeler BF, Lee C-T, Soubry A, Iversen ES, Huang Z, Murtha AP, et al. DNA Methylation of Regulatory Regions of Imprinted Genes at Birth and Its Relation to Infant Temperament. Genet Epigenet. 2016;8:59–67.Full Text Link to Item
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King KE, Kane JB, Scarbrough P, Hoyo C, Murphy SK. Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example. Biodemography Soc Biol. 2016;62(1):87–104.Full Text Link to Item
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McCullough LE, Miller EE, Mendez MA, Murtha AP, Murphy SK, Hoyo C. Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains. Clin Epigenetics. 2016;8:8.Full Text Link to Item
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Nye MD, King KE, Darrah TH, Maguire R, Jima DD, Huang Z, et al. Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort. Environ Epigenet. 2016;2(1).Full Text Link to Item
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Soubry A, Guo L, Huang Z, Hoyo C, Romanus S, Price T, et al. Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study. Clin Epigenetics. 2016;8:51.Full Text Link to Item
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Su D, Wang X, Campbell MR, Porter DK, Pittman GS, Bennett BD, et al. Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. Plos One. 2016;11(12):e0166486.Full Text Link to Item
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Peng J, Hamanishi J, Matsumura N, Abiko K, Murat K, Baba T, et al. Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer. Cancer Res. 2015 Dec 1;75(23):5034–45.Full Text Link to Item
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Sachdeva M, Dodd RD, Huang Z, Grenier C, Ma Y, Lev DC, et al. Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182. Cancer Lett. 2015 Dec 1;369(1):202–11.Full Text Link to Item
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Hemachandra LPMP, Shin D-H, Dier U, Iuliano JN, Engelberth SA, Uusitalo LM, et al. Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. Cancer Res. 2015 Nov 15;75(22):4973–84.Full Text Link to Item
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Varadaraj A, Patel P, Serrao A, Bandyopadhay T, Lee NY, Jazaeri AA, et al. Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. Neoplasia. 2015 Nov;17(11):826–38.Full Text Link to Item
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King KE, Darrah TH, Money E, Meentemeyer R, Maguire RL, Nye MD, et al. Geographic clustering of elevated blood heavy metal levels in pregnant women. Bmc Public Health. 2015 Oct 9;15:1035.Full Text Link to Item
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Ding J, Reynolds LM, Zeller T, Müller C, Lohman K, Nicklas BJ, et al. Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. Diabetes. 2015 Oct;64(10):3464–74.Full Text Link to Item
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Keenan MM, Liu B, Tang X, Wu J, Cyr D, Stevens RD, et al. ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate. Plos Genet. 2015 Oct;11(10):e1005599.Full Text Open Access Copy Link to Item
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Murphy SK, Erginer E, Huang Z, Visco Z, Hoyo C. Genotype-Epigenotype Interaction at the IGF2 DMR. Genes (Basel). 2015 Aug 28;6(3):777–89.Full Text Link to Item
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Vidal AC, Semenova V, Darrah T, Vengosh A, Huang Z, King K, et al. Maternal cadmium, iron and zinc levels, DNA methylation and birth weight. Bmc Pharmacol Toxicol. 2015 Jul 15;16:20.Full Text Link to Item
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King K, Murphy S, Hoyo C. Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status. J Epidemiol Community Health. 2015 Jul;69(7):639–47.Full Text Link to Item
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Baba T, Kang HS, Hosoe Y, Kharma B, Abiko K, Matsumura N, et al. Menstrual cyclic change of metastin/GPR54 in endometrium. Med Mol Morphol. 2015 Jun;48(2):76–84.Full Text Link to Item
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Soubry A, Murphy SK, Wang F, Huang Z, Vidal AC, Fuemmeler BF, et al. Newborns of obese parents have altered DNA methylation patterns at imprinted genes. International Journal of Obesity. 2015 Apr 9;39(4):650–7.Full Text Open Access Copy
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Nye MD, Hoyo C, Murphy SK. In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST. Toxicol in Vitro. 2015 Apr;29(3):544–50.Full Text Link to Item
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Tang X, Keenan MM, Wu J, Lin C-A, Dubois L, Thompson JW, et al. Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis. Plos Genet. 2015 Apr;11(4):e1005158.Full Text Link to Item
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Soubry A, Murphy SK, Wang F, Huang Z, Vidal AC, Fuemmeler BF, et al. Newborns of obese parents have altered DNA methylation patterns at imprinted genes. Int J Obes (Lond). 2015 Apr;39(4):650–7.Full Text Open Access Copy Link to Item
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McCullough LE, Mendez MA, Miller EE, Murtha AP, Murphy SK, Hoyo C. Associations between prenatal physical activity, birth weight, and DNA methylation at genomically imprinted domains in a multiethnic newborn cohort. Epigenetics. 2015;10(7):597–606.Full Text Link to Item
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Vidal AC, Skaar D, Maguire R, Dodor S, Musselwhite LW, Bartlett JA, et al. IL-10, IL-15, IL-17, and GMCSF levels in cervical cancer tissue of Tanzanian women infected with HPV16/18 vs. non-HPV16/18 genotypes. Infect Agent Cancer. 2015;10:10.Full Text Open Access Copy Link to Item
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Mo L, Pospichalova V, Huang Z, Murphy SK, Payne S, Wang F, et al. Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells. Plos One. 2015;10(7):e0131579.Full Text Link to Item
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Nagura M, Matsumura N, Baba T, Murakami R, Kharma B, Hamanishi J, et al. Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta. Gynecol Oncol. 2015 Jan;136(1):104–11.Full Text Link to Item
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Okamoto T, Mandai M, Matsumura N, Yamaguchi K, Kondoh H, Amano Y, et al. Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma. Mol Carcinog. 2015 Jan;54(1):35–49.Full Text Link to Item
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Kharma B, Baba T, Matsumura N, Kang HS, Hamanishi J, Murakami R, et al. STAT1 drives tumor progression in serous papillary endometrial cancer. Cancer Res. 2014 Nov 15;74(22):6519–30.Full Text Link to Item
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Nye MD, Hoyo C, Wang F, Murtha AP, Schildkraut JM, Kurtzberg J, et al. Abstract B22: Altered methylation profiles of imprinted genes in response to prenatal exposure to cigarette smoke in the Newborn Epigenetic STudy (NEST) cohort. Cancer Epidemiology, Biomarkers &Amp; Prevention. 2014 Nov 1;23(11_Supplement):B22–B22.Full Text
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Hoyo C, Daltveit AK, Iversen E, Benjamin-Neelon SE, Fuemmeler B, Schildkraut J, et al. Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort. Epigenetics. 2014 Aug;9(8):1120–30.Full Text Open Access Copy Link to Item
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Vidal AC, Smith JS, Valea F, Bentley R, Gradison M, Yarnall KSH, et al. HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA. Cancer Causes Control. 2014 Aug;25(8):1055–62.Full Text Link to Item
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Yamaguchi K, Huang Z, Matsumura N, Mandai M, Okamoto T, Baba T, et al. Epigenetic determinants of ovarian clear cell carcinoma biology. Int J Cancer. 2014 Aug 1;135(3):585–97.Full Text Link to Item
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Murphy SK. Obesity: Paternal obesity--a risk factor for autism? Nat Rev Endocrinol. 2014 Jul;10(7):389–90.Full Text Link to Item
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Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC. Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury. Genes (Basel). 2014 Jun 11;5(2):477–96.Full Text Link to Item
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Soubry A, Hoyo C, Jirtle RL, Murphy SK. A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line. Bioessays. 2014 Apr 1;36(4):359–71.Full Text
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Soubry A, Hoyo C, Jirtle RL, Murphy SK. A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. Bioessays. 2014 Apr;36(4):359–71.Full Text Link to Item
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Vidal AC, Henry NM, Murphy SK, Oneko O, Nye M, Bartlett JA, et al. PEG1/MEST and IGF2 DNA methylation in CIN and in cervical cancer. Clinical and Translational Oncology. 2014 Mar 1;16(3):266–72.Full Text
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Moylan CA, Pang H, Dellinger A, Suzuki A, Garrett ME, Guy CD, et al. Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease. Hepatology. 2014 Feb;59(2):471–82.Full Text Link to Item
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Secord AA, Teoh D, Jia J, Nixon AB, Grace L, Adams DJ, et al. Dasatinib (BMS-35482) interacts synergistically with docetaxel, gemcitabine, topotecan, and doxorubicin in ovarian cancer cells with high SRC pathway activation and protein expression. Int J Gynecol Cancer. 2014 Feb;24(2):218–25.Full Text Link to Item
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Davidson BA, Rubatt JM, Corcoran DL, Teoh DK, Bernardini MQ, Grace LA, et al. Differential Angiogenic Gene Expression in TP53 Wild-Type and Mutant Ovarian Cancer Cell Lines. Front Oncol. 2014;4:163.Full Text Link to Item
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Nye MD, Fry RC, Hoyo C, Murphy SK. Investigating Epigenetic Effects of Prenatal Exposure to Toxic Metals in Newborns: Challenges and Benefits. Med Epigenet. 2014;2(1):53–9.Full Text Link to Item
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Vidal AC, Murphy SK, Hoyo C. What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry? Journal of Vaccines and Vaccination. 2014 Jan 1;5(3).Full Text
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Vidal AC, Benjamin Neelon SE, Liu Y, Tuli AM, Fuemmeler BF, Hoyo C, et al. Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans. Genet Epigenet. 2014;6:37–44.Full Text Open Access Copy Link to Item
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Vidal AC, Smith JS, Valea F, Bentley R, Gradison M, Yarnall KSH, et al. HPV genotypes and cervical intraepithelial Neoplasiain a multiethnic cohort in the southeastern United States. Journal of Vaccines and Vaccination. 2014 Jan 1;5(3).Full Text
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Vidal AC, Smith JS, Valea F, Bentley R, Gradison M, Yarnall KSH, et al. HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA. Cancer Causes and Control. 2014 Jan 1;25(8):1055–62.Full Text
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Yamaguchi K, Matsumura N, Mandai M, Baba T, Konishi I, Murphy SK. Epigenetic and genetic dispositions of ovarian carcinomas. Oncoscience. 2014;1(9):574–9.Full Text Link to Item
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Kharma B, Baba T, Mandai M, Matsumura N, Murphy SK, Kang HS, et al. Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers. Int J Cancer. 2013 Nov;133(9):2234–44.Full Text Link to Item
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Murphy SK, Yang H, Moylan CA, Pang H, Dellinger A, Abdelmalek MF, et al. Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease. Gastroenterology. 2013 Nov;145(5):1076–87.Full Text Link to Item
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Amano Y, Yamaguchi K, Mandai M, Matsumura N, Hamanishi J, Baba T, et al. Abstract PR08: HNF1β confers resistance to oxidative stress of ovarian clear cell carcinoma. Clinical Cancer Research. 2013 Oct 1;19(19_Supplement):PR08–PR08.Full Text
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Hamanishi J, Matsumura N, Jin P, Abiko K, Horikawa N, Yamaguchi K, et al. Abstract A83: Induction of PD-L1 expression by cytotoxic agents through activation of NF-kB signal. Clinical Cancer Research. 2013 Oct 1;19(19_Supplement):A83–A83.Full Text
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Matsumura N, Yamanoi K, Amano Y, Hamanishi J, Baba T, Murphy SK, et al. Abstract B19: Functional genomics approach links anchorage-independence with tumor dormancy in ovarian cancer. Clinical Cancer Research. 2013 Oct 1;19(19_Supplement):B19–B19.Full Text
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Murphy SK. Prenatal sensitization of a postnatal trigger for metabolic disease. J Clin Invest. 2013 Jul;123(7):2786–8.Full Text Link to Item
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Vidal AC, Murphy SK, Murtha AP, Schildkraut JM, Soubry A, Huang Z, et al. Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. Int J Obes (Lond). 2013 Jul;37(7):907–13.Full Text Open Access Copy Link to Item
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Liu Y, Hoyo C, Murphy S, Huang Z, Overcash F, Thompson J, et al. DNA methylation at imprint regulatory regions in preterm birth and infection. Am J Obstet Gynecol. 2013 May;208(5):395.e1-395.e7.Full Text Link to Item
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Sfakianos GP, Iversen ES, Whitaker R, Akushevich L, Schildkraut JM, Murphy SK, et al. Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues. Gynecol Oncol. 2013 Apr;129(1):159–64.Full Text Link to Item
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Murphy SK, Hollingsworth JW. Stress: a possible link between genetics, epigenetics, and childhood asthma. Am J Respir Crit Care Med. 2013 Mar 15;187(6):563–4.Full Text Link to Item
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Soubry A, Schildkraut JM, Murtha A, Wang F, Huang Z, Bernal A, et al. Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort. Bmc Med. 2013 Feb 6;11:29.Full Text Open Access Copy Link to Item
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Alvarez Secord A, Bernardini MQ, Broadwater G, Grace LA, Huang Z, Baba T, et al. TP53 Status is Associated with Thrombospondin1 Expression In vitro. Front Oncol. 2013;3:269.Full Text Link to Item
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Bassil CF, Huang Z, Murphy SK. Bisulfite pyrosequencing. Methods Mol Biol. 2013;1049:95–107.Full Text Link to Item
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Huang Z, Bassil CF, Murphy SK. Bisulfite sequencing of cloned alleles. Methods Mol Biol. 2013;1049:83–94.Full Text Link to Item
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Huang Z, Bassil CF, Murphy SK. Methylation-specific PCR. Methods Mol Biol. 2013;1049:75–82.Full Text Link to Item
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Huang Z, Murphy SK. Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma. Front Oncol. 2013;3:131.Full Text Link to Item
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Murphy SK, Bassil CF, Huang Z. Main principles and outcomes of DNA methylation analysis. Methods Mol Biol. 2013;1049:67–74.Full Text Link to Item
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Nye MD, Hoyo C, Huang Z, Vidal AC, Wang F, Overcash F, et al. Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer. Plos One. 2013;8(2):e56325.Full Text Link to Item
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Vidal AC, Murphy SK, Murtha AP, Schildkraut JM, Soubry A, Huang Z, et al. Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. International Journal of Obesity. 2013;37(7):907–13.Full Text Open Access Copy
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Vidal AC, Murtha AP, Murphy SK, Fortner K, Overcash F, Henry N, et al. Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants. Int J Pediatr. 2013;2013:191472.Full Text Open Access Copy Link to Item
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Vidal AC, Overcash F, Murphy SK, Murtha AP, Schildkraut JM, Forman MR, et al. Associations between birth and one year anthropometric measurements and IGF2 and IGF2R genetic variants in African American and Caucasian American infants. J Pediatr Genet. 2013;2(3):119–27.Full Text Open Access Copy Link to Item
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Korch C, Spillman MA, Jackson TA, Jacobsen BM, Murphy SK, Lessey BA, et al. DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination. Gynecol Oncol. 2012 Oct;127(1):241–8.Full Text Link to Item
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Joubert BR, Håberg SE, Nilsen RM, Wang X, Vollset SE, Murphy SK, et al. 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect. 2012 Oct;120(10):1425–31.Full Text Link to Item
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Das R, Anderson N, Koran MI, Weidman JR, Mikkelsen TS, Kamal M, et al. Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. Bmc Genomics. 2012 Aug 16;13:394.Full Text Link to Item
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Liu Y, Murphy SK, Murtha AP, Fuemmeler BF, Schildkraut J, Huang Z, et al. Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. Epigenetics. 2012 Jul;7(7):735–46.Full Text Open Access Copy Link to Item
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Perkins E, Murphy SK, Murtha AP, Schildkraut J, Jirtle RL, Demark-Wahnefried W, et al. Insulin-like growth factor 2/H19 methylation at birth and risk of overweight and obesity in children. J Pediatr. 2012 Jul;161(1):31–9.Full Text Open Access Copy Link to Item
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Huang Z, Lowery WJ, Berchuck A, Murphy SK. Abstract 5363: Aggregation rather than monoclonal expansion explains ovarian cancer spheroid formation. Cancer Research. 2012 Apr 15;72(8_Supplement):5363–5363.Full Text
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Okamoto T, Yamaguchi K, Huang Z, Whitaker R, Konishi I, Berchuck A, et al. Abstract LB-87: Methylated-mediated repression of ZNF154 in ovarian cancer is associated with poor overall survival. Cancer Research. 2012 Apr 15;72(8_Supplement).Full Text
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Hoyo C, Fortner K, Murtha AP, Schildkraut JM, Soubry A, Demark-Wahnefried W, et al. Association of cord blood methylation fractions at imprinted insulin-like growth factor 2 (IGF2), plasma IGF2, and birth weight. Cancer Causes Control. 2012 Apr;23(4):635–45.Full Text Open Access Copy Link to Item
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Berchuck A, Sfakianos G, Whitaker R, Levine D, Murphy S, Marks J, et al. Frequency of the cancer genome atlas expression subtypes differs between early and advanced stage high grade serous ovarian cancers. Gynecologic Oncology. 2012 Mar;125:S133–S133.Full Text
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Murphy S, Yang H, Yamaguchi K, Huang Z, Konishi I, Berchuck A. DNA Methylation Profiles Distinguish Serous, Mucinous and Clear Cell but not Endometrioid Epithelial Ovarian Cancers. Gynecologic Oncology. 2012 Mar;125:S99–S99.Full Text
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Murphy SK, Adigun A, Huang Z, Overcash F, Wang F, Jirtle RL, et al. Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. Gene. 2012 Feb 15;494(1):36–43.Full Text Link to Item
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Murphy SK. Targeting the epigenome in ovarian cancer. Future Oncol. 2012 Feb;8(2):151–64.Full Text Link to Item
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Skaar DA, Li Y, Bernal AJ, Hoyo C, Murphy SK, Jirtle RL. The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility. Ilar J. 2012;53(3–4):341–58.Full Text Link to Item
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Hoyo C, Murphy SK, Schildkraut JM, Vidal AC, Skaar D, Millikan RC, et al. IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. Dis Markers. 2012;32(2):133–41.Full Text Link to Item
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Murphy SK, Huang Z, Hoyo C. Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. Plos One. 2012;7(7):e40924.Full Text Link to Item
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Yamamura S, Matsumura N, Mandai M, Huang Z, Oura T, Baba T, et al. The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer. Int J Cancer. 2012 Jan 1;130(1):20–8.Full Text Link to Item
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Bernal AJ, Murphy SK, Jirtle RL. Mouse models of epigenetic inheritance. 2011 Dec 1;233–49.Full Text
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Murphy SK, Berchuck A. Ovarian cancer progenitor/stem cells: Therapeutic potential. 2011 Dec 1;223–44.Full Text
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Bondurant AE, Huang Z, Whitaker RS, Simel LR, Berchuck A, Murphy SK. Quantitative detection of RASSF1A DNA promoter methylation in tumors and serum of patients with serous epithelial ovarian cancer. Gynecol Oncol. 2011 Dec;123(3):581–7.Full Text Link to Item
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Vidal AC, Murphy SK, Hernandez BY, Vasquez B, Bartlett JA, Oneko O, et al. Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian women. Infect Agent Cancer. 2011 Nov 14;6(1):20.Full Text Open Access Copy Link to Item
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Alvarez Secord A, Darcy KM, Hutson A, Huang Z, Lee PS, Jewell EL, et al. The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study. Gynecol Oncol. 2011 Nov;123(2):314–9.Full Text Link to Item
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Soubry A, Murphy S, Huang Z, Murtha A, Schildkraut J, Jirtle R, et al. The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring. Clin Epigenetics. 2011 Oct 26;3(1):2.Full Text Open Access Copy Link to Item
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Hoyo C, Murtha AP, Schildkraut JM, Jirtle RL, Demark-Wahnefried W, Forman MR, et al. Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy. Epigenetics. 2011 Jul;6(7):928–36.Full Text Open Access Copy Link to Item
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Zhang A, Skaar DA, Li Y, Huang D, Price TM, Murphy SK, et al. Novel retrotransposed imprinted locus identified at human 6p25. Nucleic Acids Res. 2011 Jul;39(13):5388–400.Full Text Link to Item
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Huang Z, Yamaguchi K, Berchuck A, Murphy SK. Abstract 3014: Quantitative accuracy of Illumina HumanMethylation27 Infinium BeadChip data assessed by pyrosequencing. Cancer Research. 2011 Apr 15;71(8_Supplement):3014–3014.Full Text
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Soubry A, Murphy SK, Huang Z, Murtha A, Schildkraut JM, Jirtle RL, et al. Abstract 2754: Maternal use of antidepressants in pregnancy is associated with hypermethylation at the IGF2 imprinted control regions in the offspring in a race-dependent fashion. Cancer Research. 2011 Apr 15;71(8_Supplement):2754–2754.Full Text
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Kang HS, Baba T, Mandai M, Matsumura N, Hamanishi J, Kharma B, et al. GPR54 is a target for suppression of metastasis in endometrial cancer. Mol Cancer Ther. 2011 Apr;10(4):580–90.Full Text Link to Item
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Teoh D, Ayeni TA, Rubatt JM, Adams DJ, Grace L, Starr MD, et al. Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells. Gynecol Oncol. 2011 Apr;121(1):187–92.Full Text Link to Item
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Sfakianos G, Yan J, Whitaker R, Murphy S, Berchuck A. Concordant gene expression profiles in matched primary and recurrent serous ovarian cancers predict platinum response. Gynecologic Oncology. 2011 Mar;120:S46–S46.Full Text
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Yamaguchi K, Baba T, Konishi I, Matsumura N, Murphy S, Huang Z, et al. Genes functionally regulated by methylation in ovarian cancer are involved in cell proliferation, development and morphogenesis. Gynecologic Oncology. 2011 Mar;120:S69–S69.Full Text
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Yamaguchi K, Baba T, Matsumura N, Mandai M, Konishi I, Berchuck A, et al. Genomewide methylation analyses reveal a prominent role of HINF1 network genes, via hypomethylation, in ovarian clear cell carcinoma. Gynecologic Oncology. 2011 Mar;120:S8–S8.Full Text
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Hoyo C, Murtha AP, Schildkraut JM, Forman MR, Calingaert B, Demark-Wahnefried W, et al. Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST). Bmc Public Health. 2011 Jan 21;11(1):46.Full Text Open Access Copy Link to Item
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Matsumura N, Huang Z, Mori S, Baba T, Fujii S, Konishi I, et al. Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer. Genome Res. 2011 Jan;21(1):74–82.Full Text Link to Item
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Matsumura N, Mandai M, Okamoto T, Yamaguchi K, Yamamura S, Oura T, et al. Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling. Cancer Sci. 2010 Dec;101(12):2658–63.Full Text Link to Item
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Bernardini MQ, Baba T, Lee PS, Barnett JC, Sfakianos GP, Secord AA, et al. Expression signatures of TP53 mutations in serous ovarian cancers. Bmc Cancer. 2010 May 26;10:237.Full Text Open Access Copy Link to Item
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Kondoh E, Mori S, Yamaguchi K, Baba T, Matsumura N, Cory Barnett J, et al. Targeting slow-proliferating ovarian cancer cells. Int J Cancer. 2010 May 15;126(10):2448–56.Full Text Link to Item
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Yamaguchi K, Mandai M, Oura T, Matsumura N, Hamanishi J, Baba T, et al. Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes. Oncogene. 2010 Mar 25;29(12):1741–52.Full Text Link to Item
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Lee PS, Teaberry VS, Bland AE, Huang Z, Whitaker RS, Baba T, et al. Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer. Int J Cancer. 2010 Mar 15;126(6):1378–89.Full Text Link to Item
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Barnett JC, Bean SM, Whitaker RS, Kondoh E, Baba T, Fujii S, et al. Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype. Gynecol Oncol. 2010 Mar;116(3):556–62.Full Text Link to Item
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Sfakianos G, Yamaguchi K, Murphy S, Berchuck A. Gene expression profiling of invasive serous ovarian cancers from formalin-fixed, paraffin-embedded tissues using DASL. Gynecologic Oncology. 2010 Mar 1;116(3):S136–7.Link to Item
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Murphy SK. Targeting ovarian cancer-initiating cells. Anticancer Agents Med Chem. 2010 Feb;10(2):157–63.Full Text Link to Item
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Barnett JC, Bean SM, Nakayama JM, Kondoh E, Murphy SK, Berchuck A. High poly(adenosine diphosphate-ribose) polymerase expression and poor survival in advanced-stage serous ovarian cancer. Obstet Gynecol. 2010 Jan;115(1):49–54.Full Text Link to Item
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Hoyo C, Schildkraut JM, Murphy SK, Chow W-H, Vaughan TL, Risch H, et al. IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas. Int J Cancer. 2009 Dec 1;125(11):2673–8.Full Text Link to Item
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Gregory SG, Connelly JJ, Towers AJ, Johnson J, Biscocho D, Markunas CA, et al. Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. Bmc Med. 2009 Oct 22;7:62.Full Text Link to Item
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Hoyo C, Murphy SK, Jirtle RL. Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies. J Epidemiol Community Health. 2009 Sep;63(9):683–4.Full Text Link to Item
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Mori S, Chang JT, Andrechek ER, Matsumura N, Baba T, Yao G, et al. Anchorage-independent cell growth signature identifies tumors with metastatic potential. Oncogene. 2009 Aug 6;28(31):2796–805.Full Text Link to Item
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Ding X, Mohd AB, Huang Z, Baba T, Bernardini MQ, Lyerly HK, et al. MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition. Br J Cancer. 2009 Jul 21;101(2):269–77.Full Text Link to Item
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Huang Z, Wen Y, Simel L, Price T, Berchuck A, Murphy SK. CTCF binding at a novel intragenic binding site is associated with elevated IGF2 expression in serous epithelial ovarian cancer. Cancer Research. 2009 May 1;69.Link to Item
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Kondoh E, Baba T, Matsumura N, Konishi I, Fujii S, Berchuck A, et al. UCN-01 is effective in targeting ovarian cancer spheroids. Cancer Research. 2009 May 1;69.Link to Item
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Berchuck A, Iversen ES, Luo J, Clarke JP, Horne H, Levine DA, et al. Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome. Clin Cancer Res. 2009 Apr 1;15(7):2448–55.Full Text Link to Item
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Kondoh E, Okamoto T, Higuchi T, Tatsumi K, Baba T, Murphy SK, et al. Stress affects uterine receptivity through an ovarian-independent pathway. Hum Reprod. 2009 Apr;24(4):945–53.Full Text Link to Item
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Baba T, Kang HS, Matsumura N, Hamanishi J, Mandai M, Berchuck A, et al. Loss of GPR54 correlates with stem cell activity in high-grade endometrial cancer. Gynecologic Oncology. 2009 Feb 1;112(2):S78–S78.Link to Item
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Barnett JC, Iverson E, Dressman H, Whitaker R, Murphy SK, Lancaster J, et al. Validation of the MAL gene as a predictor of survival in advanced-stage high-grade serous ovarian cancer. Gynecologic Oncology. 2009 Feb 1;112(2):S123–4.Link to Item
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Barnett JC, Kondoh E, Whitaker R, Murphy SK, Berchuck A. High poly (ADP-ribose) polymerase (PARP) expression is associated with poor survival in advanced-stage serous ovarian cancer. Gynecologic Oncology. 2009 Feb 1;112(2):S107–S107.Link to Item
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Barnett JC, Whitaker R, Kondoh E, Baba T, Murphy SK, Berchuck A. Ovarian cancer tumor-infiltrating regulatory T cells are associated with a metastatic phenotype. Gynecologic Oncology. 2009 Feb 1;112(2):S11–S11.Link to Item
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Horne HN, Lee PS, Murphy SK, Alonso MA, Olson JA, Marks JR. Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. Mol Cancer Res. 2009 Feb;7(2):199–209.Full Text Link to Item
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Kondoh E, Baba T, Malsumura N, Konishi I, Fujii S, Berchuck A, et al. 7-hydroxystaurosporine (UCN-01) is effective in targeting ovarian cancer spheroids. Gynecologic Oncology. 2009 Feb 1;112(2):S161–2.Link to Item
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Murphy SK, Chen L. Imprinted Neuronatin: A potential epigenetie biomarker of ovarian cancer. Gynecologic Oncology. 2009 Feb 1;112(2):S135–S135.Link to Item
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Resnick KE, Alder H, Secord AA, Whitaker R, Richardson DL, Heaphy C, et al. MiRNA patterns in ovarian cancer cell lines: Correlation with serum studies. Gynecologic Oncology. 2009 Feb 1;112(2):S115–6.Link to Item
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Yamaguchi K, Mandai M, Matsumura N, Baba T, Oura T, Matsui S, et al. Gene signature specific for ovarian clear cell carcinoma is induced by the contents of endometriotic cysts. Gynecologic Oncology. 2009 Feb 1;112(2):S132–S132.Link to Item
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Matsumura N, Huang Z, Baba T, Lee PS, Barnett JC, Mori S, et al. Yin yang 1 modulates taxane response in epithelial ovarian cancer. Mol Cancer Res. 2009 Feb;7(2):210–20.Full Text Link to Item
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Murphy SK, Huang Z, Wen Y, Simel LR, Price TM, Berchuck A. Intragenic methylation at a novel CTCF binding site is associated with elevated IGF2 expression in serous epithelial ovarian cancer. Gynecologic Oncology. 2009 Feb 1;112(2):S138–S138.Link to Item
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Baba T, Convery PA, Matsumura N, Whitaker RS, Kondoh E, Perry T, et al. Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene. 2009 Jan 15;28(2):209–18.Full Text Link to Item
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Baba T, Mori S, Matsumura N, Bernardini M, Fujii S, Berchuck A, et al. Microarray analysis identifies NSC668814 as a potentially active chemotherapeutic agent for platinum-resistant ovarian cancers with TP53 mutations. Gynecologic Oncology. 2008 Mar 1;108(3):S72–S72.Link to Item
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Bernardini MQ, Lee P, Baba T, Whitaker RS, Murphy SK, Berchuck A. Microarray analysis defines patterns of gene expression associated with mutation of TP53 in ovarian cancer. Gynecologic Oncology. 2008 Mar 1;108(3):S84–S84.Link to Item
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Kondoh E, Baba T, Matsumura N, Fujii S, Berchuck A, Murphy SK. Targeting dormant ovarian cancer cells. Gynecologic Oncology. 2008 Mar 1;108(3):S13–4.Link to Item
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Matsumura N, Huang Z, Perry T, Kroyer D, Baba T, Mori S, et al. Methylation in ovarian cancer is related to poor prognosis and suppression of the transforming growth factor signaling pathway. Gynecologic Oncology. 2008 Mar 1;108(3):S104–S104.Link to Item
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Baba T, Mori S, Matsumura N, Kariya M, Murphy SK, Kondoh E, et al. Trophinin is a potent prognostic marker of ovarian cancer involved in platinum sensitivity. Biochem Biophys Res Commun. 2007 Aug 24;360(2):363–9.Full Text Link to Item
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Hempel N, How T, Dong M, Murphy SK, Fields TA, Blobe GC. Loss of betaglycan expression in ovarian cancer: role in motility and invasion. Cancer Res. 2007 Jun 1;67(11):5231–8.Full Text Link to Item
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Spillman MA, Lacy J, Murphy SK, Whitaker RS, Grace L, Teaberry V, et al. Regulation of the metastasis suppressor gene MKK4 in ovarian cancer. Gynecol Oncol. 2007 May;105(2):312–20.Full Text Link to Item
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Price TM, Murphy SK, Younglai EV. Perspectives: the possible influence of assisted reproductive technologies on transgenerational reproductive effects of environmental endocrine disruptors. Toxicol Sci. 2007 Apr;96(2):218–26.Full Text Link to Item
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Risinger JI, Chandramouli GVR, Maxwell GL, Custer M, Pack S, Loukinov D, et al. Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression. Clin Cancer Res. 2007 Mar 15;13(6):1713–9.Full Text Link to Item
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Schildkraut JM, Murphy SK, Palmieri RT, Iversen E, Moorman PG, Huang Z, et al. Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):473–80.Full Text Link to Item
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Goh L, Murphy SK, Muhkerjee S, Furey TS. Genomic sweeping for hypermethylated genes. Bioinformatics. 2007 Feb 1;23(3):281–8.Full Text Link to Item
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O’Sullivan FM, Murphy SK, Simel LR, McCann A, Callanan JJ, Nolan CM. Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation. Evol Dev. 2007;9(6):579–89.Full Text Link to Item
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Weidman JR, Dolinoy DC, Murphy SK, Jirtle RL. Cancer susceptibility: epigenetic manifestation of environmental exposures. Cancer J. 2007;13(1):9–16.Full Text Link to Item
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Murphy SK, Huang Z, Wen Y, Spillman MA, Whitaker RS, Simel LR, et al. Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer. Mol Cancer Res. 2006 Apr;4(4):283–92.Full Text Link to Item
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Murphy SK, Nolan CM, Huang Z, Kucera KS, Freking BA, Smith TPL, et al. Callipyge mutation affects gene expression in cis: a potential role for chromatin structure. Genome Res. 2006 Mar;16(3):340–6.Full Text Link to Item
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Huang Z, Wen Y, Shandilya R, Marks JR, Berchuck A, Murphy SK. High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. Nucleic Acids Res. 2006;34(2):555–63.Full Text Link to Item
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Berchuck A, Iversen ES, Lancaster JM, Pittman J, Luo J, Lee P, et al. Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. Clin Cancer Res. 2005 May 15;11(10):3686–96.Full Text Link to Item
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Spillman MA, Schildkraut JM, Halabi S, Moorman P, Calingaert B, Bentley RC, et al. Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk. Gynecol Oncol. 2005 May;97(2):543–9.Full Text Link to Item
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Wang W, Huper G, Guo Y, Murphy SK, Olson JA, Marks JR. Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. Oncogene. 2005 Apr 14;24(16):2705–14.Full Text Link to Item
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Murphy SK, Freking BA, Smith TPL, Leymaster K, Nolan CM, Wylie AA, et al. Abnormal postnatal maintenance of elevated DLK1 transcript levels in callipyge sheep. Mamm Genome. 2005 Mar;16(3):171–83.Full Text Link to Item
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Weidman JR, Murphy SK, Nolan CM, Dietrich FS, Jirtle RL. Phylogenetic footprint analysis of IGF2 in extant mammals. Genome Res. 2004 Sep;14(9):1726–32.Full Text Link to Item
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Murphy SK, Wylie AA, Coveler KJ, Cotter PD, Papenhausen PR, Sutton VR, et al. Epigenetic detection of human chromosome 14 uniparental disomy. Hum Mutat. 2003 Jul;22(1):92–7.Full Text Link to Item
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Murphy SK, Jirtle RL. Imprinting evolution and the price of silence. Bioessays. 2003 Jun;25(6):577–88.Full Text Link to Item
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Dietz LG, Wylie AA, Rauen KA, Murphy SK, Jirtle RL, Cotter PD. Exclusion of maternal uniparental disomy of chromosome 14 in patients referred for Prader-Willi syndrome using a multiplex methylation polymerase chain reaction assay. J Med Genet. 2003 Apr;40(4):e46.Full Text Link to Item
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Freking BA, Murphy SK, Wylie AA, Rhodes SJ, Keele JW, Leymaster KA, et al. Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals. Genome Res. 2002 Oct;12(10):1496–506.Full Text Link to Item
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Li T, Vu TH, Lee K-O, Yang Y, Nguyen CV, Bui HQ, et al. An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. J Biol Chem. 2002 Apr 19;277(16):13518–27.Full Text Link to Item
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Evans HK, Wylie AA, Murphy SK, Jirtle RL. NNATresides in a micro-imprinted domain on human chromosome 20q11.2. American Journal of Human Genetics. 2001 Oct 1;69(4):346–346.Link to Item
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Murphy SK, Wylie AA, McVie-Wylie AJ, Pulford D, Nolan CM, Orton TC, et al. Development and characterization of a conditional M6p/Igf2r knockout mouse. American Journal of Human Genetics. 2001 Oct 1;69(4):363–363.Link to Item
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Evans HK, Wylie AA, Murphy SK, Jirtle RL. The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. Genomics. 2001 Sep;77(1–2):99–104.Full Text Link to Item
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Keller MA, Murphy SK, Parks GD. RNA replication from the simian virus 5 antigenomic promoter requires three sequence-dependent elements separated by sequence-independent spacer regions. J Virol. 2001 Apr;75(8):3993–8.Full Text Link to Item
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Murphy SK, Wylie AA, Jirtle RL. Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior. Genomics. 2001 Jan 1;71(1):110–7.Full Text Link to Item
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Wylie AA, Murphy SK, Orton TC, Jirtle RL. Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation. Genome Res. 2000 Nov;10(11):1711–8.Full Text Link to Item
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Murphy SK, Wylie AA, Jirtle RL. Imprinting of PEG3, the human homolog of a gene involved in nurturing behaviour. American Journal of Human Genetics. 2000 Oct 1;67(4):189–189.Link to Item
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Wylie AA, Murphy SK, Orton TC, Jirtle RL. Identification of a novel imprinted domain at human chromosome 14q32. American Journal of Human Genetics. 2000 Oct 1;67(4):190–190.Link to Item
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Murphy SK, Jirtle RL. Imprinted genes as potential genetic and epigenetic toxicologic targets. Environ Health Perspect. 2000 Mar;108 Suppl 1(Suppl 1):5–11.Full Text Link to Item
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Murphy SK, Parks GD. RNA replication for the paramyxovirus simian virus 5 requires an internal repeated (CGNNNN) sequence motif. J Virol. 1999 Jan;73(1):805–9.Full Text Link to Item
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Murphy SK, Ito Y, Parks GD. A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus. J Virol. 1998 Jan;72(1):10–9.Full Text Link to Item
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Murphy SK, Parks GD. Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5. Virology. 1997 May 26;232(1):145–57.Full Text Link to Item
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Murphy SK, Oliver JD. Effects of temperature abuse on survival of Vibrio vulnificus in oysters. Appl Environ Microbiol. 1992 Sep;58(9):2771–5.Full Text Link to Item
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Book Sections
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Moylan CA, Murphy SK. DNA Methylation: Basic Principles. In: Medical Epigenetics. 2016. p. 11–31.Full Text
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Moylan C, Murphy S. DNA Methylation: Basic Principles. In: Trygve T, editor. Medical Epigenetics. Amsterdam: Academic Press; 2016. p. 11–32.
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Skaar DA, Murphy SK, Hoyo C. Effects of environmentally acquired heavy metals and nutrients on the epigenome and phenotype. In: Molecular and Integrative Toxicology. 2016. p. 139–69.Full Text
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Taylor MM, Murphy SK. Systems Biology and the Epigenome. In: Systems Biology in Toxicology and Environmental Health. 2015. p. 43–56.Full Text
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Murphy S, Taylor MM. Systems Biology and the Epigenome. In: Fry R, editor. Systems Biology in Toxicology and Environmental Health. Amsterdam: Academic Press; 2015. p. 43–56.
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Murphy S, Hoyo C. Sculpting our future: Environmental nudging of the imprintome. In: Randy J, Fred T, editors. Environmental Epigenomics in Health and Disease. Berlin Heidelburg: Springer-Verlag; 2013. p. 51–73.
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Bernal AJ, Murphy SK, Jirtle RL. Mouse Models of Epigenetic Inheritance. In: Handbook of Epigenetics: The New Molecular and Medical Genetics. 2010. p. 233–49.Full Text
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Murphy S, Jirtle R. Non-genotoxic causes of cancer. In: Alison MR, Gooderham NG, editors. The Cancer Handbook. Palgrave Macmillan; 2002. p. 317–33.
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Conference Papers
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Bukowski A, Hoyo C, Hudgens MG, Brewster WR, Valea F, Bentley RC, et al. Extended human papillomavirus genotyping to predict progression to high-grade cervical precancer: A prospective cohort study in the southeastern United States. In: Cancer Research. 2022.Link to Item
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Chandramouli SA, Brown N, Wang Y, Vidal A, Marchesoni J, Abdelmalek MF, et al. AHRR METHYLATION MEDIATES THE EFFECTS OF MATERNAL SMOKING ON LIVER FAT CONTENT AND METABOLIC HEALTH IN CHILDREN. In: Hepatology. 2022. p. S1531–2.Link to Item
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Moylan CA, Jima D, Mavis A, Diehl AM, Bashir M, Hyun J, et al. PRE-TEENS EXPOSED PRENATALLY TO MATERNAL OBESITY EXHIBIT PERSISTENT DNA METHYLATION CHANGES THAT ASSOCIATE WITH METABOLIC ABNORMALITIES, INCLUDING HIGH LIVER FAT. In: Hepatology. 2022. p. S1522–3.Link to Item
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Cabezas M, Parish A, Mavis A, Niedzwiecki D, Maguire R, Murphy SK, et al. EVEN MODEST ELEVATIONS IN LIVER FAT ASSOCIATE WITH METABOLIC ABNORMALITIES IN CHILDREN AND MAY INDICATE FUTURE RISK FOR NAFLD AND ASSOCIATED COMPLICATIONS. In: Hepatology. 2021. p. 1107A-1108A.Link to Item
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Crute CE, Hall S, Landon C, Garner A, Murphy SK, Feng L. Maternal Exposure to an Environmentally Relevant Mixture of Per- and Polyfluoroalkyl Substances (PFAS) Leads to Adverse Pregnancy Outcomes in a New Zealand White Rabbit Model. In: Reproductive Sciences. 2021. p. 255A-255A.Link to Item
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King D, Martinez M, Lloyd D, Maguire R, Hoyo C, Meyer JN, et al. Analysis of Illumina 450K DNA Methylation in NEST Cord Blood Reveals Sex Differences at Mitochondrial Genes in the Nuclear Genome. In: Environmental and Molecular Mutagenesis. 2020. p. 34–5.Link to Item
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Moylan CA, Jima D, Mavis A, Diehl AM, Buie S, Bashir M, et al. NONALCOHOLIC FATTY LIVER AND ITS RISK FACTORS ASSOCIATE WITH DIFFERENTIAL DNA METHYLATION IN THE PERIPHERAL BLOOD OF PRE-TEENAGE CHILDREN. In: Hepatology. 2020. p. 931A-931A.Link to Item
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Maddala R, Murphy SK, Rao V. S100A4 deficiency-induced aberrant gene expression during lens differentiation is epigenetically regulated through altered Histone 3 lysine methylation marking. In: Investigative Ophthalmology & Visual Science. ASSOC RESEARCH VISION OPHTHALMOLOGY INC; 2019.Link to Item
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Moylan CA, Grenier C, Hyun J, Du K, Henao R, Abdelmalek MF, et al. DYSREGULATED DNA METHYLATION OF FGFR2, CASP1, AND BCAT1 ASSOCIATES WITH NONALCOHOLIC FATTY LIVER DISEASE SEVERITY AND CAN BE IDENTIFIED IN PERIPHERAL BLOOD. In: Gastroenterology. W B SAUNDERS CO-ELSEVIER INC; 2019. p. S1360–1.Link to Item
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Moylan CA, Sorrow PA, Mavis A, Bashir M, Jima D, Maguire R, et al. Obesity and Nonalcoholic Fatty Liver Disease in Childhood Associate with Altered DNA Methylation in Early Life. In: Hepatology. WILEY; 2018. p. 949A-950A.Link to Item
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Kollins S, Levin E, Price T, Murphy S. Delta-9-Tetrahydrocannabinol Exposure Alters Sperm Methylation Profiles: Concurrent Results From Humans and Rats. In: Neuropsychopharmacology. NATURE PUBLISHING GROUP; 2017. p. S642–3.Link to Item
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Li X, Moylan CA, Baker SS, Liu W, Baker RD, Murphy SK, et al. Altered liver methylome and transcriptome provide evidence for epigenetic contribution to NAFLD pathogenesis. In: Hepatology. WILEY; 2017. p. 1071A-1072A.Link to Item
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Moylan CA, Mavis AM, Bashir MR, Malik D, Bozdogan E, Buie S, et al. Visceral and subcutaneous adipose tissue measurements associate with increased metabolic risk for NAFLD in pre-pubertal obese children. In: Hepatology. WILEY; 2017. p. 665A-665A.Link to Item
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Murphy SK, Schrott R, Visco Z, Huang Z, Grenier C, Mitchell J, et al. Environment and Gametic Epigenetic Reprogramming. In: Environmental and Molecular Mutagenesis. WILEY; 2017. p. S28–S28.Link to Item
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Huang Z, Foster B, Grenier C, Sfakianos G, Whitaker R, Berchuck A, et al. Abstract 1991: Enhanced role of the extracellular matrix in ovarian cancer recurrence. In: Cancer Research. American Association for Cancer Research (AACR); 2017. p. 1991–1991.Full Text
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Moylan CA, Giraldo RH, Murphy SK, Diehl AM, Abdelmalek MF. Differential DNA Methylation in Whole Blood Reflects that in Liver and Distinguishes Patients with Advanced NAFLD Fibrosis from Those with Normal Histology: A Potential Non-Invasive Tool. In: Gastroenterology. Elsevier BV; 2017. p. S1069–70.Full Text
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Bradley MS, Boudreau M-H, Grenier C, Huang Z, Murphy S, Siddiqui NY. STANDARDIZATION OF RNA PROCESSING FROM URINE SEDIMENT IN A CLINICAL SETTING. In: Neurourology and Urodynamics. WILEY-BLACKWELL; 2017. p. S18–S18.Link to Item
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Bradley MS, Burke E, Grenier C, Amundsen CL, Murphy S, Siddiqui NY. URINARY METHYLATION PATTERNS IN WOMEN WITH INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME. In: Neurourology and Urodynamics. WILEY-BLACKWELL; 2017. p. S17–8.Link to Item
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Moylan CA, Wegermann KJ, Henao RG, Murphy SK, Diehl AM, Abdelmalek MF. BCAT1 Is Associated with Clinical Decompensation in Nonalcoholic Fatty Liver Disease: a Pilot Study. In: American Journal of Gastroenterology. Ovid Technologies (Wolters Kluwer Health); 2016. p. S381–S381.Full Text
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Murphy SK, Keyhan S, Guo L, Tomins K, Taylor M, Joglekar R, et al. Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles. In: Environmental and Molecular Mutagenesis. WILEY-BLACKWELL; 2016. p. S39–S39.Link to Item
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Horikawa N, Abiko K, Matsumura N, Hamanishi J, Murphy S, Baba T, et al. Abstract B63: Expression of VEGF in ovarian cancer suppresses tumor immunity through recruitment of myeloid derived suppressor cells. In: Clinical Cancer Research. American Association for Cancer Research (AACR); 2016. p. B63–B63.Full Text
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Moylan CA, Murphy SK, Grenier C, Abdelmalek MF, Diehl AM. DNA Methylation Profiles of Fibrosis-Associated Gene in Blood Reflects Liver Fibrosis Severity in Human Nonalcoholic Fatty Liver Disease. In: Hepatology. WILEY-BLACKWELL; 2015. p. 648A-649A.Link to Item
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Huang Z, Visco Z, Sfakianos G, Whitaker R, Berchuck A, Murphy S. Abstract POSTER-BIOL-1319: Temporal shifts in the epigenetic regulation of tight junctions from primary to recurrent ovarian cancer. In: Clinical Cancer Research. American Association for Cancer Research (AACR); 2015.Full Text
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Huang Z, Visco Z, Sfakianos G, Whitaker R, Berchuck A, Murphy SK. Abstract 2236: Emergence of epigenetic regulation of tight junction genes in recurrent serous epithelial ovarian cancer. In: Cancer Research. American Association for Cancer Research (AACR); 2015. p. 2236–2236.Full Text
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Varadaraj A, Patel P, Serrao A, Bandyopadhyay T, Lee NY, Jazaeri A, et al. Abstract 3912: GDF2 promotes anoikis susceptibility in ovarian and breast epithelia. In: Cancer Research. American Association for Cancer Research (AACR); 2015. p. 3912–3912.Full Text
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Mendez M, Grabich S, Nahm S, Murphy S, Hoyo C. Diet during pregnancy and disparities in fetal growth: the NEST cohort. In: Faseb Journal. FEDERATION AMER SOC EXP BIOL; 2015.Link to Item
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Cobb LP, Whitaker R, Hall A, Broadwater G, Murphy SK, Berchuck A, et al. Evaluation of ERRα expression and association with survival in advanced ovarian cancer. In: Gynecologic Oncology. Elsevier BV; 2015. p. 204–204.Full Text
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Ding J, Reynolds LM, Zeller T, Muller C, Lohman K, Huang Z, et al. Alterations of a Cellular Cholesterol Metabolism Network is a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. In: Circulation. LIPPINCOTT WILLIAMS & WILKINS; 2014.Link to Item
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Kharma B, Baba T, Matsumura N, Kang HS, Murakami R, Yamaguchi K, et al. Abstract LB-123: Novel function of STAT1 pathway as a modulator of tumor progression in serous papillary endometrial cancer. In: Cancer Research. American Association for Cancer Research (AACR); 2014.Full Text
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Stevens EV, Whitaker R, Guinet A, Chang C-Y, Grenier C, Marks J, et al. Abstract 4570: Role of ERRalpha in ovarian cancer. In: Cancer Research. American Association for Cancer Research (AACR); 2014. p. 4570–4570.Full Text
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Park J, Huang Z, Berchuck A, Murphy S. Abstract 4767: Preclinical mouse model of recurrent epithelial ovarian cancer. In: Cancer Research. American Association for Cancer Research (AACR); 2013. p. 4767–4767.Full Text
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Wang X, Pittman GS, Su D, Adamski KN, Campbell MR, Joubert BR, et al. Abstract 3647: Dose-dependent alteration of CpG methylation in AHRR and GFI1 in mononuclear cell DNA of smokers. In: Cancer Research. American Association for Cancer Research (AACR); 2013. p. 3647–3647.Full Text
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Murphy SK, Nye MD, Hoyo C. Methylation at Imprinted Insulin-Like Growth Factor-2 (IGF2) Is Vulnerable to Lead Exposure in Human Embryonic Kidney Cells. In: Reproductive Sciences. SAGE PUBLICATIONS INC; 2013. p. 203A-204A.Link to Item
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Garrett ME, Moylan CA, Gibson J, Yang H, Pang H, Dellinger A, et al. Expression QTL analysis of a gene expression signature which predicts advanced non-alcoholic fatty liver disease. In: Hepatology. WILEY-BLACKWELL; 2012. p. 267A-268A.Link to Item
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Moylan CA, Yang H, Pang H, Dellinger A, Suzuki A, Tillmann HL, et al. Epigenetic Regulation of Gene Expression in NAFLD. In: Gastroenterology. W B SAUNDERS CO-ELSEVIER INC; 2012. p. S929–S929.Link to Item
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Baba T, Kharma B, Mandai M, Yoshioka Y, Hamanishi J, Matsumura N, et al. Utilization of genomic signatures to identify Fludarabine and Temsirolimus as candidate drugs with high efficacy to chemo-refractory endometrial cancers. In: Gynecologic Oncology. Elsevier BV; 2012. p. S138–S138.Full Text
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Baba T, Kang H, Mandai M, Hamanishi J, Kharma B, Matsumura N, et al. Metastin-10 suppresses invasion of endometrial cancer cells. In: Gynecologic Oncology. ACADEMIC PRESS INC ELSEVIER SCIENCE; 2010. p. S76–S76.Link to Item
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Matsumura N, Mandai M, Okamoto T, Yamaguchi K, Oura T, Baba T, et al. Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling. In: Gynecologic Oncology. ACADEMIC PRESS INC ELSEVIER SCIENCE; 2010. p. S155–S155.Link to Item
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Murphy S, Overcash F, Huang Z, Vasquez B, Hernandez B, Obure J, et al. Progressive epigenetic deregulation of insulin-like growth factor 2 in cervical cancer precursors in HIV plus and HIV- patients. In: Gynecologic Oncology. ACADEMIC PRESS INC ELSEVIER SCIENCE; 2010. p. S38–S38.Link to Item
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Fortner K, Murtha A, Hoyo C, Overcash F, Huang Z, Schildkraut J, et al. 70: Epigenetic orchestration of circulating insulin-like growth factor-2 levels in cord blood. In: American Journal of Obstetrics and Gynecology. Elsevier BV; 2009. p. S39–S39.Full Text
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Murphy SK, Jayes FL, Feng L, Huang Z, Leppert PC. Methylation of THBS1, the Gene Encoding Thrombospondin-1 in Uterine Fibroids and Myometrium. In: Reproductive Sciences. SAGE PUBLICATIONS INC; 2009. p. 214A-214A.Link to Item
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Murphy SK, Jayes FL, Feng L, Huang Z, Leppert PC. Altered IGF2/H19 Imprint Center Methylation in Uterine Fibroids but Not in Adjacent Myometrium. In: Reproductive Sciences. SAGE PUBLICATIONS INC; 2009. p. 216A-216A.Link to Item
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Lee PS, Teaberry V, Bland AE, Huang Z, Secord AA, Berchuck A, et al. MAL, a gene associated with survival in epithelial ovarian cancer, is epigenetically regulated. In: Gynecologic Oncology. ACADEMIC PRESS INC ELSEVIER SCIENCE; 2008. p. S125–S125.Link to Item
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Baba T, Convery PA, Matsumura N, Whitaker RS, Perry T, Huang Z, et al. Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer. In: Gynecologic Oncology. 2008. p. S104–S104.Link to Item
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Baba T, Convey P, Matsumura N, Whitaker RS, Perry T, Huang Z, et al. Stem cell marker CD133 (PROMININ-1) is epigenetically regulated in ovarian cancer. In: Cancer Biomarkers. 2008. p. 175–6.Link to Item
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Murphy SK, Gusberg AH, Huang Z, Simel LR, Whitaker RS, Berchuck A. Overexpression of imprinted DLK1 in epithelial ovarian cancer. In: Cancer Research. AMER ASSOC CANCER RESEARCH; 2006.Link to Item
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Schildkraut JM, French A, Calingaert B, Bentley RC, Murphy S, Marks JR, et al. Molecular epidemiology of cyclin E overexpression in epithelial ovarian cancer. In: Cancer Research. AMER ASSOC CANCER RESEARCH; 2006.Link to Item
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Huang Z, Gusberg AH, Whitaker RS, Berchuck A, Murphy SK. YY1 imprint status and role in ovarian carcinogenesis. In: Cancer Research. AMER ASSOC CANCER RESEARCH; 2006.Link to Item
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Schildkraut JM, Berchuck A, Murphy S, Marks J, Moorman P, Calingaert B, et al. Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. In: Cancer Epidemiology Biomarkers & Prevention. AMER ASSOC CANCER RESEARCH; 2004. p. 1897S-1897S.Link to Item
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Dietz L, Wylie AA, Rauen KA, Murphy SK, Jirtle RL, Cotter PD. Exclusion of maternal uniparental disomy of chromosome 14 in Prader-Willi syndrome referrals using a rapid methylation PCR assay. In: American Journal of Human Genetics. UNIV CHICAGO PRESS; 2002. p. 553–553.Link to Item
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Datasets
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Murphy S, King D, Hoyo C. Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes. 2022.Data Access
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Murphy S, Whitaker R, Sfakianos G, Berchuck A, Huang Z. Gene Expression using Affymetrix Human Genome U133 Plus 2 Arrays from 16 Primary and Recurrent Serous Epithelial Ovarian Cancers. 2021.Data Access
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Murphy S, Sfakianos G, Whitaker R, Berchuk A, Huang Z. Primary and recurrent (second-look surgery) serous epithelial ovarian cancers Illumina Infinium HumanMethylation450 BeadChip data. 2021.Data Access
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Schrott R, Raburn D, Kollins S, Levin E, Corcoran D, Boudreau M-H, et al. Data from: Cannabinoid exposure and altered DNA methylation in rat and human sperm. 2020.Data Access
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Artistic Works & Non-Print Media
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Digital Media
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- Teaching & Mentoring
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Recent Courses
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Advising & Mentoring
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Junior Faculty
Gynecologic Oncology Fellows
Cynthia Moylan, MD, Duke University, Gastroenterology
K Award Co-Mentor
Naz Siddiqui, MD, Duke University, OB/GYN – Urogynecology
K Award Co-Mentor, K23 recipient
Megan Bradley, MD, Duke University, OB/GYN – Urogynecology
AUGS Foundation Co-Mentor
Sherika Hill, PhD, UNC-Chapel Hill / Duke University
Fellow, Center for Developmental Science
Dissertation Committees
Dana Dolinoy, Duke University, UPGG, 2007
Kristin Maloney, Duke University, UPGG, 2009 (Masters)
Radhika Das, Duke University, UPGG, 2010
Autumn Bernal, Duke University, UPGG, 2012
Amanda Lea, Duke University, Biology, 2017
Kim Cocce, Duke University, Medical Scientist Training Program, 2017
Valerie Rojas, Pharmacology Sciences Training Program, MS 2014
Nathaniel Mabe, Pharmacology and Cancer Biology, PhD 2019
Rashmi Joglekar, ITEHP, Nicholas School of the Environment, PhD 2019
Rose Schrott, ITEHP, Nicholas School of the Environment, Candidate
Emma Dolan, Pharmacology and Cancer Biology, Candidate
Christine Crute, ITEHP, Nicholas School of the Environment, Candidate
Dillon King, ITEHP, Nicholas School of the Environment
Nicole Wanner, College of Veterinary Medicine, University of Minnesota
Monique Spillman, MD/PhD, Gyn-Onc Fellow, Duke University, 2003-2006
Current position: Texas Oncology – Baylor, Dallas, TX
Paula Lee, MD, Gyn-Onc Fellow, Duke University, 2004-2007
Current position: Assistant Professor, Duke University
Amy E. BonDurant, MD, Gyn-Onc Fellow, Duke University, 2005-2008
Current position: Pacific Gynecology Specialists, Seattle, WA
Marcus Bernardini, MD, Visiting Fellow, University of Toronto, 2006-2007
Current position: Assistant Professor, University of Toronto
Jason Cory Barnett, MD, Gyn-Onc Fellow, Duke University, 2007-2008
Current position: Department of OB/GYN, Fort Sam Houston Texas
Gregory Sfakianos, MD, Gyn-Onc Fellow, Duke University, 2009-2010
Current position: St. Francis Gynecologic Oncology, Columbus, GA
William J. Lowery, MD, Gyn-Onc Fellow, Duke University, 2010-2011
Current position: Gynecologic Oncologist, US Army, Rockville, MD
Brittany Davidson, MD, Gyn-Onc Fellow, Duke University, 2013-2014
Current position: Assistant Professor, Duke University
Reproductive Endocrinology Fellows
Sanaz Keyhan, MD, Duke University, 2015-2016
Current position: Palo Alto Medical Foundation, San Jose, California
Kelly Acharya, MD, Duke University, 2017-2018
Current position: Assistant Professor of OBGYN, Reproductive Endocrinology and Infertility, Duke University
Stephanie Smeltzer, MD, Duke University, 2018-2019
Current position: Atlanta Center for Reproductive Medicine
Jessica Selter, MD, Duke University, 2020-2021
Shilpi Agrawala, MD, Duke University, 2022-2023
Postdoctoral Fellows
Noriomi Matsumura, MD/PhD, 2005-2007
Current position: Professor, Obstetrics and Gynecology, Kyoto University, Kindai University
Tsukasa Baba, MD/PhD, 2006-2008
Current position: Associate Professor, Gynecologic Oncology, Kyoto University
Eiji Kondoh, MD, 2007-2009
Current position: Assistant Professor, Gynecology and Obstetrics, Kyoto University
Ken Yamaguchi, MD/PhD, 2009-2011
Current position: Chief of Obstetrics and Gynecology, Japan Baptist Hospital, Kyoto University
Abayomi Adigun, PhD, 2010-2011
Current position: Manager, Investment Staff, Duke University
Lihong Zhu, MD, 2011-2012
Current position: Assistant Professor, Peking University, Beijing
Ellen Stevens, PhD, 2011- 2013
Current position: Senior Scientist, Baebies
Takako Okamato, MD, 2011-2014
Monica Nye, PhD, 2011-2014
Current position: Assistant Professor, UNC-Charlotte
Michele Taylor, PhD, 2014-2016
Current position: Toxicologist, Environmental Protection Agency
Graduate Students
Rotations
Katrina Slemmons, Molecular Cancer Biology 2013
Amelia Poplawski, Molecular Cancer Biology 2015
Sara Payne, Molecular Cancer Biology 2015-2016
Yihan Liao, Cellular and Molecular Biology 2016
Emily Liang, Integrated Toxicology and Environmental Health Program 2017
Laura Childers, Integrated Toxicology and Environmental Health Program 2018
Sam Hall, Integrated Toxicology and Environmental Health Program 2018
Thesis
Valerie Rojas, Pharmacology Scientist Training Program (Master’s) 2013-2015
Current position: Regulatory Consultant, Syneos Health Commercial Solutions
Dissertation
Rashmi Joglekar, PhD, Integrated Toxicology and Environmental Health Program 2015-2019
Current position: Earthjustice, Scientist, Toxic Exposure and Health Program, Washington, DC
Rose Schrott, PhD, Integrated Toxicology and Environmental Health Program 2017-2021
Current position: Postdoctoral Fellow, Johns Hopkins University
Christine Crute, PhD, Integrated Toxicology and Environmental Health Program 2018-2022
Current position: Science Corps Fellow, Morocco
Emma Dolan, Pharmacology and Cancer Biology 2018 -
PhD Candidate
Dillon King, Integrated Toxicology and Environmental Health Program 2019 -
PhD Candidate
Medical Students – Third Year Research
Vanessa Teaberry Schroder, 2004-2005
Current position: Assistant Professor of Surgery, Duke University
Patricia Convery, 2006-2007
Current position: Private Practice, Raleigh. North Carolina
Kerone Walker, 2008-2009
Current Position: Obstetrics and Gynecology, UCLA Medical Center
Jaemin Park, (Duke-NUS), 2011-2013 (two years of research)
Current position: Investment Professional at Partner’s Group
Isabel Rodriguez, 2014-2015
Current position: Gynecologic Oncology Fellowship, University of Washington, Seattle
Barbara Blachut, (Washington University, St. Louis), summer, 2017
Cassie Hobbs, 2017-2018
Undergraduate Students
Yaqing Wen, Duke University, 2004-2006
Bouncer Program, Independent Study Student
Current position: Board Certified Internist, Charlottesville, Virginia
Jacob Berchuck, Duke University, 2004
Current position: Medical Oncologist, Dana Farber Cancer Institute
Lisa Chen, Duke University, 2005-2007
Independent Study Student, Honors Thesis Student
Current position: Clinical Instructor, Ophthalmology, Stanford University
Natasha Duggan, University of California, San Francisco, 2006-2009
Current position: Postdoctoral Trainee, University of Miami
Nancy Anoruo, University of Florida, Gainesville, 2006
Institute for Genome Sciences and Policy Summer Research Program
Current position: Adjunct Instructor in Biology, American University
Cara Davis, University of North Carolina, Asheville, 2008
Current position: Project Specialist, INC Research, Raleigh, North Carolina
Jack Fitzgibbons, Duke University, 2010
Independent Study Student
Current position: Director of Strategic Initiatives, SMS Assist, Chicago, Illinois
Masashi Ono, University of North Carolina, Asheville, 2010
Christopher Bassil, Duke University, 2011-2012
Current position: Medical Scientist Training Program, Duke University
Shamaita Majumdar, Duke University, 2011-2014
Independent Study Student, Honors Thesis Student
Current position: Medical Student, Washington University St. Louis, Missouri
Clara Lee, Duke University, 2012-2014
Independent Study Student, Honors Thesis Student
Current position: Medical Student, Emory University, Atlanta, Georgia
Jason Chin, Duke University, 2012-2014
Independent Study Student
Sonya Jooma, Duke University, 2013-2014
Independent Study Student
Current Position: Health Policy Analyst, NHGRI
Lisa Guo, Duke University, 2013-2014
Independent Study Student, Honors Thesis Student
Brittany Wenger, Duke University, 2013-2014
TIME’s Thirty Under Thirty
Kelli Tomins, Duke University, 2014-2016
Independent Study Student
Current Position: Research Fellow, NIH
Zachary Visco, Duke University, 2014-2017
Current Position: Medical Student, State University of New York Medical School
Michelle Dalson, Duke University, 2015
Marie Boudreau, Appalachian State University, 2014 - 2017
Sabrina Simpson, Boston University, 2015 - 2017
Catherine Birtles, McGill University, 2015
Ethan Whitaker, Cambell University, 2015 - 2017
Melody Iro, Duke University, 2016
Brad Foster, Duke University, 2016
Kamyar Yazdani, Duke University Class of 2020, 2016 - 2019
Independent Study Student
Katarina Stephan, Duke University, 2017
Katherine Maitland, Duke University Class of 2021, 2017 – 2018
Independent Study Student, Biology Honors Research, Graduation with Distinction
Olivia Neely, Duke University Class of 2020, 2018 – 2020
Independent Study Student
Jim Liu, Duke University Class of 2019
Independent Study Student
Kaycie Hutcheson, Duke University Class of 2020
Michael Williams, Duke University Class of 2021
High School Students
Danielle Dejournet, North Carolina School of Science, and Math, 2013-2014
Kennedy Bridges, North Carolina School of Science and Math, 2014-2015
Deepika Senthil, North Carolina School of Science and Math, 2015-2016
Esther Son, North Carolina School of Science and Math, 2017-2018
Andy Liu, North Carolina School of Science and Math, 2018-2019
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Teaching Activities
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1994-1997, Medical Microbiology Laboratory Instructor, Wake Forest University
1994-1997, Advanced Topics in Microbiology and Immunology Instructor, Wake Forest University
1997, Medical Microbiology Tutor, Wake Forest University
1997, Fundamentals of Virology, ad hoclecturer, Wake Forest University
2000, Duke University Bioinformatics Shared Resources Seminar Series: An Introduction to Profile Hidden Markov Models
2004, Duke University Bouncer Program Undergraduate Summer Research Program
2006, Duke University Institute for Genome Sciences and Policy Summer Fellowship Program (National Science Foundation Research Experience for Undergraduates)
2005-2007, Independent Research, Mentor (Honors Research): Imprinted NNAT: a Potential Epigenetic Biomarker of Ovarian Cancer
2012-2014, Independent Research, Mentor (Honors Research): The Role of Imprinted Gene MEG3 in Epithelial Ovarian Cancer
2013-2016, Independent Research, Mentor (Honors Research): Male Overweight/Obesity and Sperm Epigenome Disturbances at Differentially Methylated Regions of Imprinted Genes
2017-2018, Independent Research, Mentor (Honors Research):Effects of Cannabis-Linked Changes in DNA Methylation on AHRR Gene Transcription2018-2019, Independent Research, Mentor (Honors Research): Analyzing the Heritable Effects of Nicotine Exposure on the Sperm Epigenome
2019-2020, Independent Research, Mentor: Let's Be Blunt: The effect of cannabis-associated DNA methylation on downstream transcription of multiple repeats in the aryl hydrocarbon receptor repressor (AHRR) gene in sperm cells
Lecturer
PATH 786.01 / Duke Merits: 2013, 2016
PATH-786 / Translational Pathobiology: 2017
ENV-537 / Environmental Health : 2015, 2016
CBI-206 / Anesthesiology-445C (Physiology and Medicine of Extreme Environments): 2015
ENV-290 / Special Topics in Environmental Sciences and Policy: 2016
ENV-819 / Mechanisms in Toxicology: 2017
HOUSECS 59.14 / House Course (Intro to Epigenetics: How Environment Shapes Our Genes): 2018
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- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- Impacts of Cannabis Use on Spermatogenesis. National Institute on Drug Abuse Course: Frontiers in Addiction Research and Pregnancy. June 8, 2021 2021
- The paternal preconception environment: Don't discount dads. National Institute of Environmental Health Sciences Epigenetics and Stem Cell Laboratories Seminar Series. February 18, 2021 2021
- Packing a Punch: Preconception Paternal Priming of Potential Prental and Postnatal Problems from Partaking in Pot. Beyond Genes: Heritable Impacts of Tobacco, Cannabis and Related Products. November 20, 2020 2020
- Our Heritage: Beyond Our Father’s Genes?. Womxn'sHealthCollaborative. October 20, 2020 2020
- Cannabinoids and the sperm epigenome. Altered States of Cannabis Regulation: Informing Policy with Science. Duke Center on Addiction & Behavior Change. April 17, 2019 2019
- Is Smoking Weed Destroying Your Sperm?. Sunday Night Live with Cormac Moore. FM104 Dublin. February 3, 2019 - February 3, 2019 2019
- Paternal cannabinoid exposure alters the sperm methylome. Advanced Genetics, Genomic Medicine Conference. 2019 2019
- Keynote: Cannabis Use and the Sperm Epigenome. GradX Talks at Duke. Society of Duke Fellows. April 4, 2018 2018
- Are there Earlier Origins of Early Origins? . Reproductive Sciences Laboratories Seminar Series. National Institute of Environmental Health Science. 2018 2018
- Cannabis Use Modifies the Human Sperm Methylome. Environmental Mutagenesis and Genomics Society Annual Meeting. 2017 2017
- Communicating the Complexities of Scientific Research. Dissemination and Integration Session. Environmental Health Sciences Fest, 50-Year Anniversary Festival Honoring the NIEHS. 2016 2016
- Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles. Environmental Mutagenesis and Genomics Society Annual Meeting. 2016 2016
- Epigenetic Impacts of Exposure, Past, Present and Future. United States Environmental Protection Agency, Cutting Edge Talk. 2016 2016
- Life Course of the Methylome. Barretos Cancer Hospital Research Seminars. 2016 2016
- #duetoepigenetics #whatdoesthatmean #mustbevoodooscience. Pediatric Environmental Health Specialty Units joint meeting with the Children’s Environmental Health Centers. 2015 2015
- Communicating Epigenetics to the Public. Science Retreat on Epigenetics. National Institute of Environmental Health Sciences, Division of Extramural Research and Training. 2015 2015
- Life Cycle of the Epigenome. Toxicology Seminar Series. North Carolina State University. 2015 2015
- Epigenetics and Imprinting in Preterm Birth: Implications for the Future,. Annual Meeting, Satellite Symposium. Society of Gynecologic Investigation. 2013 2013
- Dynamics of the Epigenome. Department of Obstetrics and Gynecology. University of Colorado Anschutz Medical Campus. 2012 2012
- DNA Methylation at Imprinted Gene Regulatory Regions: Utility as Biosensors for Historical Exposures. Qiagen Automation Roadshow. Qiagen. 2011 2011
- Epigenetic Mechanisms and Genomic Imprintin. Epigenetics of Autism Spectrum Disorders: Current Knowledge, Existing Opportunities and Future Directions. Autism Speaks. 2011 2011
- Seeking the Silenced in Epithelial Ovarian Cancer. Cellular and Molecular Biology Seminar Series. National Institute of Environmental Health Science. 2010 2010
- The Newborn Epigenetics STudy (NEST). Qiagen Roadshow. NC Biotech Center. 2009 2009
- The Newborn Epigenetics STudy (NEST). Qiagen Seminar. 2009 2009
- Methylation of the IGF2/H19 Imprinted Domain in Early Development: the Newborn Epigenetics STudy (NEST).. Association of Molecular Pathology Meeting. 2008 2008
- Alteration of Cancer Causing Genes: Mutation and Promoter Methylation. Society of Gynecologic Oncologists 36th Annual Meeting. 2005 2005
- Alteration of Cancer Causing Genes: Mutation and Promoter Methylation. Society of Gynecologic Oncologists 36th Annual Meeting. 2005 2005
- Sequence-Dependent and -Independent Features of the Paramyxovirus Promoter that Govern Viral RNA Replication. Triangle Virology Spring Symposium. North Carolina Biotechnology Center. 1998 1998
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Outreach & Engaged Scholarship
- Bass Connections Team Leader. Impacts of Maternal Exposure to E-waste on Birth Outcomes. 2020 - 2021 2020 - 2021
- Before Conception: Impact of Exposure on the Methylome. NIEHS Partnerships for Environmental Public Health Webinar Series. 2017 2017
- Epigenetic links between secondhand smoke exposure and ADHD. EPA/NIEHS Children's Centers Webinar Series. 2014 2014
- Traffic Cops of the Genome. Periodic Tables Science Café. Durham Museum of Life and Science. 2012 2012
- Speaker. Gail Parkins Memorial Ovarian Cancer Awareness Educational Forum. 2011 2011
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Service to the Profession
- Member, Grants Committee. Society for Reproductive Investigation. 2022 - 2025 2022 - 2025
- NIH Study Section, ad hoc reviewer. . ZRG1 PSE-C (02) M NICHD Infectious Disease, Reproductive Health, Cancer and Aging. National Institutes of Health. 2021 2021
- Reviewer, Pennsylvania Department of Health. 2021 2021
- Chair. Triangle Consortium for Reproductive Biology. 2020 - 2021 2020 - 2021
- Advisor. Ohana Biosciences. November 2019 2019
- NIH Study Section, ad hoc member. Infectious Diseases, Reproductive Health, Asthma and Pulmonary Conditions (IRAP). National Institutes of Health. 2019 2019
- NIH Study Section, ad hoc member. ZES1 LWJ-K (U)2 NIEHS Human Health Exposure Analysis Resource (HHEAR) U2Cs UnTargeted Analysis Review Committee. 2019 2019
- NIH Study Section, ad hoc member. ZES1 LWJ-K (U2)2, NIEHS Human Health Exposure Analysis Resource (HHEAR) U2Cs Targeted Analysis Review Committee. 2019 2019
- Co-Chair. Triangle Consortium for Reproductive Biology. 2018 - 2019 2018 - 2019
- Grant Reviewer. John Templeton Foundation. 2018 - 2019 2018 - 2019
- Grant Reviewer. Pennsylvania Department of Health. 2018 2018
- NIH Study Section, ad hoc member. ZGM1 RCB-Y (C1) NIGMS Review of COBRE Applications. 2017 2017
- NIH Study Section, ad hoc member. ZHD1 DSR-L (50) NICHD Integrative Research in Gynecology Health. 2017 2017
- Grant reviewer. Target Ovarian Cancer (UK), Innovation in Ovarian Cancer Award. 2016 2016
- Organizer. EHS Fest, Dissemination and Integration Panel. National Institute of Environmental Health Sciences. 2016 2016
- Editorial Review Board. Environmental Epigenetics. Oxford Academic. 2015 2015
- NIH Study Section, ad hoc member. ZES1 LWJ-J (UC) Environmental Evaluation and Support Review Committee. 2015 2015
- Peer Reviewer. Cancer and the Environment, DOHaD, Environmental Epigenetics, JCI, Nature Communications, Neurotoxicology, Placenta, Reproductive Toxicology, Epigenetics, Epigenomics, iScience. 2015 2015
- Director. Duke Epigenetics and Epigenomics Program. Duke University. 2014 - 2015 2014 - 2015
- Editorial Board. Genetics and Epigenetics. Libertas Academica. 2014 2014
- Grant reviewer. Department of Defense Ovarian Cancer Research Program, ECI Panel Member. 2014 2014
- Grant reviewer. The John Templeton Foundation. 2014 2014
- Grant reviewer. University of California at Los Angeles Seed Grant for Biomedical Research. 2014 2014
- Grant reviewer. University of North Carolina Nutrition Center Grant. 2014 2014
- Leader. Epigenetics Working Group. NIH/USEPA Children's Environmental Health and Disease Prevention Research Centers. 2014 - 2017 2014 - 2017
- Organizer. Cognitive Impairment Caused by Developmental Neurotoxic Exposure: Mechanisms, Consequences and Therapeutic Treatment. 2014 2014
- Grant reviewer. Netherlands Organisation for Scientific Research. 2013 2013
- Organizer. How Epigenomic Effects Mediate Persisting Actions of Developmental Toxicants. 2013 2013
- Grant reviewer. Autism Speaks Basic and Clinical Grants Review Meeting. 2012 2012
- NIH Study Section, ad hoc member. ZRG1 GGG-R (02) S Genes, Genomes and Genetics Review Group. 2012 2012
- Executive Committee Member. Duke Epigenetics and Epigenomics Program. Duke University. 2011 2011
- Grant reviewer. Autism Speaks Basic and Clinical Grants Review Meeting. 2011 2011
- Grant reviewer. Mary Kay Foundation Innovative/Translational Research Grants. 2011 2011
- Organizer. Environmental Epigenetics of Autism Spectrum Disorders Meeting. Autism Speaks. 2011 2011
- NIH Study Section, ad hoc member. ZRG1 OBT-A (55) R, Recovery Act Limited Competition. 2010 2010
- Consultant. United States Department of Justice Autism vs. Secretary of Health and Human Services. 2008 2008
- Discussant. Society of Gynecologic Oncologists 39th Annual Meeting. Society of Gynecologic Oncologists. 2008 2008
- Abstract Coordinator and Senior Reviewer. Environmental Epigenomics, Imprinting and Disease Susceptibility Conference. National Institute of Environmental Health Sciences. 2006 2006
- Grant Reviewer. Cancer Research UK. 2006 2006
- Session Moderator. Stem Cells session; Environmental Epigenomics, Imprinting and Disease Susceptibility Conference. National Institute of Environmental Health Sciences. 2006 2006
- Study section member. Department of Defense Ovarian Cancer Research Program OC-1 Panel Member. 2005 2005
- NIH Study Section, ad hoc member. ZHD1 DRG-D (SG) Special Emphasis Panel Review Committee. 2004 2004
- Treasurer. Beta Beta Beta Biological Honor Society. University of North Carolina at Charlotte. 1989 - 1991 1989 - 1991
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Service to Duke
- Curriculum Review Committee, Duke University Program in Environmental Health . 2021 2021
- Duke University. Chair, Integrated Toxicology and Environmental Health Program Admissions Committee. 2020 2020
- Duke Women’s Reproductive Health Research Advisory Committee. 2020 2020
- Reviewer, Duke REACH Equity Career Development Awards. 2020 2020
- Office of the Provost, Duke University. Academic Programs Committee. 2018 - 2021 2018 - 2021
- Obstetrics and Gynecology. Charles Hammond Research Fund Committee. 2015 2015
- Director and Organizer. Duke Epigenetics and Epigenomics Program (DEEP) Mini-Symposium: Environmental Epigenetics. 2014 2014
- Director and Organizer. Duke Epigenetics and Epigenomics Program Monthly Journal Club. 2014 - 2015 2014 - 2015
- Director. Duke Epigenetics and Epigenomics Program. School of Medicine. 2014 - 2015 2014 - 2015
- MGM702 Pathogenesis and Immunity Study Section. School of Medicine. 2014 2014
- DCI Gynecologic Cancer Research Meetings. Gynecologic Oncology. 2012 - 2015 2012 - 2015
- Executive Committee. Duke Epigenetics and Epigenomics Program (DEEP). School of Medicine. 2011 2011
- Judge. AOA Medical Honor Society Scientific Research Symposium. School of Medicine. 2011 - 2012 2011 - 2012
- Reviewer. Path to Independence / K Club . School of Medicine. 2011 2011
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Academic & Administrative Activities
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2020-2021 Faculty Advisor, DevilThon, Fundraising Organization for Duke Children’s Hospital, Part of the Children’s Miracle Network
2020- Co-PI, T32ES021432 Training Grant, Duke University Program in Environmental Health
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