Journal ArticleFuture Oncol · April 4, 2024
Patients with cancer have the unique ability of being able to offer valuable insights into how cancer therapeutics may impact the overall patient experience and improve clinical outcomes. Patient engagement could therefore contribute to tailoring treatment ...
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Journal ArticleContemp Clin Trials · November 2022
>276,000 Americans will be diagnosed with invasive breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ this year and most will undergo breast surgery as part of their care. Although prognosis is excellent, many patients experience persist ...
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Journal ArticleSupport Care Cancer · December 2021
PURPOSE: Cancer survivors are often sedentary. Self-monitoring may promote physical activity through self-activation. We conducted a pilot trial to evaluate whether wearable activity tracker with personalized text message feedback would increase physical a ...
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Journal ArticleBMC Fam Pract · November 18, 2021
BACKGROUND: As treatments for cancer have improved, more people are surviving cancer. However, compared to people without a history of cancer, cancer survivors are more likely to die of cardiovascular disease (CVD). Increased risk for CVD-related mortality ...
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Chapter · September 15, 2021
Screening for inherited predisposition to cancer and germline genetic testing are part of the standard of care for breast cancer management, with implications for immediate and survivorship management. The advent of multigene next-generation sequencing pan ...
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Journal ArticleJ Natl Compr Canc Netw · July 28, 2021
Palliative care has evolved to be an integral part of comprehensive cancer care with the goal of early intervention to improve quality of life and patient outcomes. The NCCN Guidelines for Palliative Care provide recommendations to help the primary oncolog ...
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Journal ArticleContemp Clin Trials · March 2021
BACKGROUND: Women with breast cancer in medically underserved areas are particularly vulnerable to persistent pain and disability. Behavioral pain interventions reduce pain and improve outcomes. Cancer patients in medically underserved areas receive limite ...
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Book · January 1, 2021
This book provides a clinically useful resource for evaluation and management of the symptoms and issues that burden survivors of breast cancer. Improvements to breast cancer screening and treatment have resulted in more patients than ever before having be ...
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Chapter · January 1, 2021
Medical management guidelines provide lifelines for busy clinicians trying to determine the best approach for individual patient scenarios. By identifying, collating, reviewing, and categorizing published results, guidelines save time and provide valuable ...
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Journal ArticleContemp Clin Trials · May 2020
Breast cancer survivors with type 2 diabetes are at high risk for cancer recurrence, serious health complications, more severe symptoms, psychological distress, and premature death relative to breast cancer survivors without diabetes. Maintaining glycemic ...
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Journal ArticleAm J Manag Care · April 2020
Palliative and hospice care services produce immense benefits for patients living with serious illness and for their families. Due to the national shift toward value-based payment models, health systems and payers share a heightened awareness of the need t ...
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Journal ArticleJ Pain Symptom Manage · February 2020
CONTEXT: Patients with advanced cancer face a life-limiting condition that brings a high symptom burden that often includes pain, fatigue, and psychological distress. Psychosocial interventions have promise for managing symptoms but need additional tailori ...
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Journal ArticleJ Clin Oncol · September 10, 2019
PURPOSE: Older women with breast cancer remain under-represented in clinical trials. The Cancer and Leukemia Group B 49907 trial focused on women age 65 years and older. We previously reported the primary analysis after a median follow-up of 2.4 years. Sta ...
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Journal ArticleContemp Clin Trials · January 2019
Adjuvant endocrine therapy (AET) is used to prevent recurrence and reduce mortality for women with hormone receptor positive breast cancer. Poor adherence to AET is a significant problem and contributes to increased medical costs and mortality. A variety o ...
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Journal ArticleJ Psychosoc Oncol · 2019
The purpose of this study was to refine and test a mobile-health behavioral cancer pain coping skills training protocol for women with breast cancer and pain from medically underserved areas. Three focus groups (Phase 1) were used to refine the initial pro ...
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Journal ArticleJ Cancer Surviv · December 2018
PURPOSE: Many cancer survivors continue to smoke. Further, most survivors also report high levels of persistent pain and smoke in response to pain. The investigators tested the feasibility, acceptability, and preliminary efficacy of a smoking cessation pro ...
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Journal ArticleJ Geriatr Oncol · May 2018
OBJECTIVE: Chemotherapy preference refers to a patient's interest in receiving chemotherapy. This study examined whether chemotherapy preference was associated with toxicity, efficacy, quality of life (QoL), and functional outcomes during and after complet ...
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Journal ArticleJ Natl Compr Canc Netw · August 2017
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care for patients with cancer. These NCCN Guidelines Insights summarize and provide context for the updated guidelines recommendations regarding hospice and end ...
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Journal ArticleJ Natl Compr Canc Netw · January 2016
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care for patients with cancer. The NCCN Guidelines are intended to provide guidance to the primary oncology team on the integration of palliative care into onco ...
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Journal ArticleFuture Oncol · April 4, 2024
Patients with cancer have the unique ability of being able to offer valuable insights into how cancer therapeutics may impact the overall patient experience and improve clinical outcomes. Patient engagement could therefore contribute to tailoring treatment ...
Full textLink to itemCite
Journal ArticleContemp Clin Trials · November 2022
>276,000 Americans will be diagnosed with invasive breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ this year and most will undergo breast surgery as part of their care. Although prognosis is excellent, many patients experience persist ...
Full textLink to itemCite
Journal ArticleSupport Care Cancer · December 2021
PURPOSE: Cancer survivors are often sedentary. Self-monitoring may promote physical activity through self-activation. We conducted a pilot trial to evaluate whether wearable activity tracker with personalized text message feedback would increase physical a ...
Full textLink to itemCite
Journal ArticleBMC Fam Pract · November 18, 2021
BACKGROUND: As treatments for cancer have improved, more people are surviving cancer. However, compared to people without a history of cancer, cancer survivors are more likely to die of cardiovascular disease (CVD). Increased risk for CVD-related mortality ...
Full textLink to itemCite
Chapter · September 15, 2021
Screening for inherited predisposition to cancer and germline genetic testing are part of the standard of care for breast cancer management, with implications for immediate and survivorship management. The advent of multigene next-generation sequencing pan ...
Full textLink to itemCite
Journal ArticleJ Natl Compr Canc Netw · July 28, 2021
Palliative care has evolved to be an integral part of comprehensive cancer care with the goal of early intervention to improve quality of life and patient outcomes. The NCCN Guidelines for Palliative Care provide recommendations to help the primary oncolog ...
Full textLink to itemCite
Journal ArticleContemp Clin Trials · March 2021
BACKGROUND: Women with breast cancer in medically underserved areas are particularly vulnerable to persistent pain and disability. Behavioral pain interventions reduce pain and improve outcomes. Cancer patients in medically underserved areas receive limite ...
Full textLink to itemCite
Book · January 1, 2021
This book provides a clinically useful resource for evaluation and management of the symptoms and issues that burden survivors of breast cancer. Improvements to breast cancer screening and treatment have resulted in more patients than ever before having be ...
Full textCite
Chapter · January 1, 2021
Medical management guidelines provide lifelines for busy clinicians trying to determine the best approach for individual patient scenarios. By identifying, collating, reviewing, and categorizing published results, guidelines save time and provide valuable ...
Full textCite
Journal ArticleContemp Clin Trials · May 2020
Breast cancer survivors with type 2 diabetes are at high risk for cancer recurrence, serious health complications, more severe symptoms, psychological distress, and premature death relative to breast cancer survivors without diabetes. Maintaining glycemic ...
Full textOpen AccessLink to itemCite
Journal ArticleAm J Manag Care · April 2020
Palliative and hospice care services produce immense benefits for patients living with serious illness and for their families. Due to the national shift toward value-based payment models, health systems and payers share a heightened awareness of the need t ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Pain Symptom Manage · February 2020
CONTEXT: Patients with advanced cancer face a life-limiting condition that brings a high symptom burden that often includes pain, fatigue, and psychological distress. Psychosocial interventions have promise for managing symptoms but need additional tailori ...
Full textLink to itemCite
Journal ArticleJ Clin Oncol · September 10, 2019
PURPOSE: Older women with breast cancer remain under-represented in clinical trials. The Cancer and Leukemia Group B 49907 trial focused on women age 65 years and older. We previously reported the primary analysis after a median follow-up of 2.4 years. Sta ...
Full textLink to itemCite
Journal ArticleContemp Clin Trials · January 2019
Adjuvant endocrine therapy (AET) is used to prevent recurrence and reduce mortality for women with hormone receptor positive breast cancer. Poor adherence to AET is a significant problem and contributes to increased medical costs and mortality. A variety o ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Psychosoc Oncol · 2019
The purpose of this study was to refine and test a mobile-health behavioral cancer pain coping skills training protocol for women with breast cancer and pain from medically underserved areas. Three focus groups (Phase 1) were used to refine the initial pro ...
Full textLink to itemCite
Journal ArticleJ Cancer Surviv · December 2018
PURPOSE: Many cancer survivors continue to smoke. Further, most survivors also report high levels of persistent pain and smoke in response to pain. The investigators tested the feasibility, acceptability, and preliminary efficacy of a smoking cessation pro ...
Full textLink to itemCite
Journal ArticleJ Geriatr Oncol · May 2018
OBJECTIVE: Chemotherapy preference refers to a patient's interest in receiving chemotherapy. This study examined whether chemotherapy preference was associated with toxicity, efficacy, quality of life (QoL), and functional outcomes during and after complet ...
Full textLink to itemCite
Journal ArticleJ Natl Compr Canc Netw · August 2017
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care for patients with cancer. These NCCN Guidelines Insights summarize and provide context for the updated guidelines recommendations regarding hospice and end ...
Full textLink to itemCite
Journal ArticleJ Natl Compr Canc Netw · January 2016
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care for patients with cancer. The NCCN Guidelines are intended to provide guidance to the primary oncology team on the integration of palliative care into onco ...
Full textLink to itemCite
Journal ArticleJ Natl Compr Canc Netw · August 2015
CHAMBER was a regional educational initiative for providers of care to patients with HER2+ breast cancer. The study goals were to (1) enhance testing for HER2/neu overexpression in patients with invasive breast cancer; (2) increase the appropriate use of t ...
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Journal ArticleJ Natl Compr Canc Netw · October 2014
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care for patients with cancer. These NCCN Guidelines Insights summarize the NCCN panel's discussions and guideline updates from 2013 and 2014. These include mod ...
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Journal ArticleJ Oncol Pract · May 2013
PURPOSE: Creating an effective platform for multidisciplinary tumor conferences can be challenging in the rural community setting. The Duke Cancer Network created an Internet-based platform for a multidisciplinary conference to enhance the care of patients ...
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Journal ArticleJ Natl Compr Canc Netw · October 1, 2012
These guidelines were developed and updated by an interdisciplinary group of experts based on clinical experience and available scientific evidence. The goal of these guidelines is to help patients with cancer experience the best quality of life possible t ...
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Journal ArticleOncologist · 2011
PURPOSE: For patients with metastatic colorectal cancer (mCRC), no standard therapy exists after progression on 5-fluorouracil, oxaliplatin, irinotecan, bevacizumab, and cetuximab or panitumumab. Preclinical data demonstrated that combined vascular endothe ...
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Journal ArticleJ Pain Symptom Manage · January 2011
CONTEXT: Lung cancer is one of the most common cancers in the United States and is associated with high levels of symptoms, including pain, fatigue, shortness of breath, and psychological distress. Caregivers and patients are adversely affected. However, p ...
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Journal ArticleBiol Blood Marrow Transplant · January 2010
The purpose of this study was to evaluate the efficacy and safety of short-course bortezomib, melphalan, prednisone (VMP) in previously untreated multiple myeloma as frontline therapy for transplant-ineligible patients and induction prior to autologous ste ...
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Journal ArticleBreast Cancer Res Treat · December 2006
Several reports have suggested that breast cancer patients with elevated serum levels of interleukin-6 (IL-6) have a worse prognosis than patients with lower levels. We have studied IL-6 in breast cancer cell lines and have shown that autocrine production ...
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Journal ArticleJ Pain Symptom Manage · March 2005
This preliminary study tested the efficacy of a partner-guided cancer pain management protocol for patients who are at the end of life. Seventy-eight advanced cancer patients meeting criteria for hospice eligibility and their partners were randomly assigne ...
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Journal ArticlePain · May 2003
This preliminary study examined the self-efficacy of family caregivers with regard to helping cancer patients manage pain at end of life. A sample of 63 family caregivers of hospice-eligible cancer patients with pain provided ratings of their self-efficacy ...
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Journal ArticleLancet Oncol · March 2003
Advances in health care and changing demographics worldwide have led to an ageing population whose care at the end of life has become increasingly complicated. Clinicians face a difficult challenge in the effective management of symptoms and suffering of e ...
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Journal ArticleJ Clin Oncol · February 15, 2002
PURPOSE: Eniluracil (776C85), a potent inactivator of dihydropyrimidine dehydrogenase, allows fluorouracil (5-FU) to be administered orally on a schedule that simulates continuous-infusion 5-FU. The primary objective of this study was to estimate the objec ...
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Journal ArticleAm J Med · April 1997
The identification of genetic mutations thought to be directly responsible for the development of breast cancer represents a major advance in our understanding of this disease. Mutations in BRCA1 and BRCA2 are thought to be responsible for the majority of ...
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Journal ArticleCancer Chemother Pharmacol · 1997
PURPOSE: The purpose of this trial was to evaluate tumor cytoreduction by all-trans retinoic acid (ATRA) in patients with metastatic breast cancer and to characterize the initial pharmacokinetics of this agent. METHODS: The study was a single institution, ...
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Journal ArticleJ Infus Chemother · 1996
Previous phase II studies of continuous infusion Fluorouracil (5-FU) (CI 5-FU) in refractory metastatic breast cancer have shown modest activity with low toxicity. Its activity in a first-line setting has not been formally tested. Patients were eligible if ...
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Journal ArticleOncology (Williston Park) · January 1994
Allogeneic and autologous bone marrow transplantation are performed with increasing frequency for a variety of malignancies as well as certain nonmalignant disorders. Physical toxicities associated with treatment are often substantial. Patients may also ex ...
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