Tai-ping Sun
Professor of Biology
The diterpenoid phytohormone gibberellin (GA) plays pivotal roles in regulating growth and development throughout the life cycle of higher plants. Mutations affecting GA biosynthesis or GA response were the key to control plant stature in wheat and rice that led to dramatically increased grain yield and contributed greatly to the success of the ‘Green Revolution’ in the 1960s. By multi-faceted approaches using the reference plant Arabidopsis, my lab has made major breakthroughs in elucidating the sites and regulatory mechanisms of GA biosynthesis, and the conserved molecular events of GA perception and the early GA signaling pathway. We identified the nuclear transcriptional regulators DELLA proteins, which function as master growth repressors by inhibiting all aspects of GA responses. Binding of GA to its nuclear receptor GID1 enhances the GID1-DELLA interaction, which in turn leads to the rapid proteolysis of DELLA through the ubiquitin-proteasome pathway, and allows transcriptional reprogramming of GA-responsive genes. We and other researchers further showed that GA-GID1-DELLA is a key regulatory module that controls plant growth by integrating internal developmental cues, and external biotic and abiotic signals (light, cold, salt and pathogen stresses). DELLA proteins play a central role in these processes via direct protein-protein interactions with key transcription factors. Our recent studies using genetic and physiological analyses together with chemical biology methods indicate that DELLA’s binding affinity to interacting proteins are oppositely regulated by two novel O-linked glycosylations on specific Ser/Thr residues: O-linked N-acetylglucosamine (O-GlcNAc) modification reduces DELLA activity, whereas O-fucosylation enhances DELLA activity. We are investigating the global functions of O-GlcNAcylation and O-fucosylation in regulating plant development.
Current Appointments & Affiliations
- Professor of Biology, Biology, Trinity College of Arts & Sciences 2006
Contact Information
- 3104 French Family Science Center, Durham, NC 27708
- Box 90338, Durham, NC 27708-0338
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tai.ping.sun@duke.edu
(919) 613-8166
- Background
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Education, Training, & Certifications
- Ph.D., Duke University 1987
- B.S., National Tsing Hua University (Taiwan) 1980
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Previous Appointments & Affiliations
- Associate Professor of Biology, Biology, Trinity College of Arts & Sciences 2000 - 2006
- Associate Professor of Botany, Biology, Trinity College of Arts & Sciences 1999 - 2000
- Assistant Professor, Biology, Trinity College of Arts & Sciences 1992 - 1998
- Recognition
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In the News
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APR 13, 2023 Duke Research -
JAN 26, 2022
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Awards & Honors
- AAAS Fellow. American Association for the Advancement of Science. 2021
- Highly Cited Researchers. Clarivate Analytics. 2016
- Highly Cited Researchers. Thomson Reuters. 2015
- Highly Cited Researcher. Thomson Reuters. 2014
- Distinguished Research Award. International Plant Growth Substances Association . 2010
- Expertise
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Subject Headings
- Research
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Selected Grants
- Elucidation of the Roles of Protein Glycosyltransferases SlSPY and SlSECs in Tomato Fruit Development awarded by Department of Agriculture 2023 - 2027
- Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2027
- Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
- Molecular Mechanism of Master Growth Repressor DELLA Signaling in Arabidopsis awarded by National Science Foundation 2018 - 2023
- Functional Analysis of Protein O-Glycosylation in Regulating Nuclear Growth Repressor DELLA and Plant Development in Arabidopsis awarded by National Institutes of Health 2012 - 2023
- Plasmonics-Enhanced Optical Imaging Systems for Bioenergy Research awarded by Department of Energy 2018 - 2022
- DELLA-ARF/IAA Interactions Mediate Crosstalk between Gibberellin and Auxin Signaling in Regulating Fruit Development in Tomato awarded by Department of Agriculture 2013 - 2021
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Multi-functional Plasmonics Nanoprobes for Cellular Sensing and Imaging awarded by Department of Energy 2015 - 2019
- Acquisition of a MALDI-TOF Mass Spectrometer System at Duke University awarded by North Carolina Biotechnology Center 2017 - 2018
- Regulation of DELLA Activity by Post-Translational Modifications and Complex Formation in Arabidopsis awarded by National Science Foundation 2004 - 2013
- Gibberellin Signaling and Parthenocarpic Fruit Development awarded by Department of Agriculture 2009 - 2013
- Molecular Mechanism of Giberellin Signalling Repression by the DELLA protein RGA in Arabidopsis awarded by National Science Foundation 2007 - 2011
- Developmental and Light Regulation of the Gibberellin 3B-Hydroxylase Genes in Arabidopsis awarded by Department of Agriculture 2001 - 2007
- Analysis of gibberellin signal transduction pathway in Arabidopsis awarded by National Science Foundation 2003 - 2007
- Regulation of the Gibberellin Biosynthetic Genes GA1 and GA2 in Arabidopsis awarded by Cooperative State Research Service (CSRS) 1999 - 2002
- Functional Analysis of RGA, A Negative Regulator of Gibberellin Signaling in Arabidopsis awarded by National Science Foundation 1998 - 2002
- Regulatory Mechanisms of Gibberellin Biosynthesis and Response in Arabidopsis awarded by National Science Foundation 1997 - 2002
- Cloning and Characterization of a New Locus RGA Involved in Gibberellin Signal Transduction in Arabidopsis awarded by National Science Foundation 1999 - 2000
- Regulatory Mechanisms of Gibberellin Biosynthesis in Arabidopsis awarded by Department of Agriculture 1995 - 1999
- Cloning and Characterization of a New Locus RGA Involved in Gibberellin Signal Transduction in Arabidopuis awarded by National Science Foundation 1997 - 1998
- Regulatory Mechanisms of Gibberellin Biosynthesis and Response in Arabidopsis awarded by Cooperative State Research Service (CSRS) 1995 - 1997
- Gibberellin Regulated Growth and Development in Arabidopsis awarded by Cooperative State Research Service (CSRS) 1992 - 1995
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Hu, Jianhong, Xiao Li, and Tai-Ping Sun. “Four class A AUXIN RESPONSE FACTORs promote tomato fruit growth despite suppressing fruit set.” Nature Plants 9, no. 5 (May 2023): 706–19. https://doi.org/10.1038/s41477-023-01396-y.Full Text
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Kumar, Shivesh, Yan Wang, Ye Zhou, Lucas Dillard, Fay-Wei Li, Carly A. Sciandra, Ning Sui, et al. “Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY.” Nat Commun 14, no. 1 (March 20, 2023): 1538. https://doi.org/10.1038/s41467-023-37279-1.Full Text Open Access Copy Link to Item
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Cupil-Garcia, Vanessa, Joy Q. Li, Stephen J. Norton, Ren A. Odion, Pietro Strobbia, Luca Menozzi, Chenshuo Ma, et al. “Plasmonic nanorod probes' journey inside plant cells for in vivo SERS sensing and multimodal imaging.” Nanoscale 15, no. 13 (March 2023): 6396–6407. https://doi.org/10.1039/d2nr06235f.Full Text
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Zentella, Rodolfo, Yan Wang, Emily Zahn, Jianhong Hu, Liang Jiang, Jeffrey Shabanowitz, Donald F. Hunt, and Tai-Ping Sun. “SPINDLY O-fucosylates nuclear and cytoplasmic proteins involved in diverse cellular processes in plants.” Plant Physiology 191, no. 3 (March 2023): 1546–60. https://doi.org/10.1093/plphys/kiad011.Full Text
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Sun, Tai-Ping. “Novel nucleocytoplasmic protein O-fucosylation by SPINDLY regulates diverse developmental processes in plants.” Current Opinion in Structural Biology 68 (June 2021): 113–21. https://doi.org/10.1016/j.sbi.2020.12.013.Full Text
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Crawford, B. M., H. N. Wang, P. Strobbia, R. Zentella, Z. M. Pei, T. P. Sun, and T. Vo-Dinh. “Plasmonic Nanobiosensing: From in situ plant monitoring to cancer diagnostics at the point of care.” Jphys Photonics 2, no. 3 (July 7, 2020). https://doi.org/10.1088/2515-7647/ab9714.Full Text
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Wang, Yan, Yuqing He, Chen Su, Rodolfo Zentella, Tai-Ping Sun, and Lei Wang. “Nuclear Localized O-Fucosyltransferase SPY Facilitates PRR5 Proteolysis to Fine-Tune the Pace of Arabidopsis Circadian Clock.” Molecular Plant 13, no. 3 (March 2020): 446–58. https://doi.org/10.1016/j.molp.2019.12.013.Full Text
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Yang, Emily J., Chan Yul Yoo, Jiangxin Liu, He Wang, Jun Cao, Fay-Wei Li, Kathleen M. Pryer, et al. “NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.” Nat Commun 10, no. 1 (June 14, 2019): 2630. https://doi.org/10.1038/s41467-019-10517-1.Full Text Open Access Copy Link to Item
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Strobbia, Pietro, Yang Ran, Bridget M. Crawford, Vanessa Cupil-Garcia, Rodolfo Zentella, Hsin-Neng Wang, Tai-Ping Sun, and Tuan Vo-Dinh. “Inverse Molecular Sentinel-Integrated Fiberoptic Sensor for Direct and in Situ Detection of miRNA Targets.” Analytical Chemistry 91, no. 9 (May 2019): 6345–52. https://doi.org/10.1021/acs.analchem.9b01350.Full Text
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Crawford, Bridget M., Pietro Strobbia, Hsin-Neng Wang, Rodolfo Zentella, Maxim I. Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth M. Kemner, and Tuan Vo-Dinh. “Plasmonic Nanoprobes for in Vivo Multimodal Sensing and Bioimaging of MicroRNA within Plants.” Acs Applied Materials & Interfaces 11, no. 8 (February 2019): 7743–54. https://doi.org/10.1021/acsami.8b19977.Full Text
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Yang, E. J., C. Y. Yoo, J. Liu, H. Wang, J. Cao, F. Li, K. M. Pryer, T. Sun, D. Weigel, and P. Zhou. “NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.” Nature Communications 10, no. 1 (2019): 1–13.Open Access Copy
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Hu, Jianhong, Alon Israeli, Naomi Ori, and Tai-Ping Sun. “The Interaction between DELLA and ARF/IAA Mediates Crosstalk between Gibberellin and Auxin Signaling to Control Fruit Initiation in Tomato.” The Plant Cell 30, no. 8 (August 2018): 1710–28. https://doi.org/10.1105/tpc.18.00363.Full Text
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Shinozaki, Yoshihito, Kentaro Ezura, Jianhong Hu, Yoshihiro Okabe, Camille Bénard, Duyen Prodhomme, Yves Gibon, Tai-Ping Sun, Hiroshi Ezura, and Tohru Ariizumi. “Identification and functional study of a mild allele of SlDELLA gene conferring the potential for improved yield in tomato.” Scientific Reports 8, no. 1 (August 2018): 12043. https://doi.org/10.1038/s41598-018-30502-w.Full Text
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Zentella, Rodolfo, Ning Sui, Benjamin Barnhill, Wen-Ping Hsieh, Jianhong Hu, Jeffrey Shabanowitz, Michael Boyce, et al. “The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA.” Nat Chem Biol 13, no. 5 (May 2017): 479–85. https://doi.org/10.1038/nchembio.2320.Full Text Open Access Copy Link to Item
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Hirano, Yoshinori, Masahiro Nakagawa, Tomoe Suyama, Kohji Murase, Maya Shirakawa, Seiji Takayama, Tai-Ping Sun, and Toshio Hakoshima. “Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD.” Nature Plants 3 (February 2017): 17010. https://doi.org/10.1038/nplants.2017.10.Full Text
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Park, Jeongmoo, Dong-Ha Oh, Maheshi Dassanayake, Khoa Thi Nguyen, Joe Ogas, Giltsu Choi, and Tai-Ping Sun. “Gibberellin Signaling Requires Chromatin Remodeler PICKLE to Promote Vegetative Growth and Phase Transitions.” Plant Physiology 173, no. 2 (February 2017): 1463–74. https://doi.org/10.1104/pp.16.01471.Full Text
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Zhou, Xin, Zhong-Lin Zhang, Jeongmoo Park, Ludmila Tyler, Jikumaru Yusuke, Kai Qiu, Edward A. Nam, et al. “The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.” Plant Physiology 171, no. 4 (August 2016): 2760–70. https://doi.org/10.1104/pp.16.00154.Full Text
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Zentella, Rodolfo, Jianhong Hu, Wen-Ping Hsieh, Peter A. Matsumoto, Andrew Dawdy, Benjamin Barnhill, Harriëtte Oldenhof, et al. “O-GlcNAcylation of master growth repressor DELLA by SECRET AGENT modulates multiple signaling pathways in Arabidopsis.” Genes Dev 30, no. 2 (January 15, 2016): 164–76. https://doi.org/10.1101/gad.270587.115.Full Text Open Access Copy Link to Item
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Acheampong, Atiako Kwame, Jianhong Hu, Ariel Rotman, Chuanlin Zheng, Tamar Halaly, Yumiko Takebayashi, Yusuke Jikumaru, et al. “Functional characterization and developmental expression profiling of gibberellin signalling components in Vitis vinifera.” Journal of Experimental Botany 66, no. 5 (March 2015): 1463–76. https://doi.org/10.1093/jxb/eru504.Full Text
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Sun, Tai-ping. “Plant Science. Sex and the single fern.” Science (New York, N.Y.) 346, no. 6208 (October 2014): 423–24. https://doi.org/10.1126/science.1260948.Full Text
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Gallego-Giraldo, C., J. Hu, C. Urbez, M. D. Gomez, T. -. P. Sun, and M. A. Perez-Amador. “Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis.” Plant Journal, 2014.
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Miyamoto, Takafumi, Robert DeRose, Allison Suarez, Tasuku Ueno, Melinda Chen, Tai-ping Sun, Michael J. Wolfgang, Chandrani Mukherjee, David J. Meyers, and Takanari Inoue. “Rapid and orthogonal logic gating with a gibberellin-induced dimerization system.” Nature Chemical Biology 8, no. 5 (March 2012): 465–70. https://doi.org/10.1038/nchembio.922.Full Text
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Bai, M. Y., J. X. Shang, E. Oh, M. Fan, Y. Bai, R. Zentella, T. -. P. Sun, and Z. -. Y. Wang. “Brassinosteroid, gibberellin, and phytochrome signalling pathways impinge on a common transcription module in Arabidopsis.” Nature Cell Biology 14 (2012): 810.
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Chapman, Elisabeth J., Kathleen Greenham, Cristina Castillejo, Ryan Sartor, Agniezska Bialy, Tai-Ping Sun, and Mark Estelle. “Hypocotyl transcriptome reveals auxin regulation of growth-promoting genes through GA-dependent and -independent pathways.” Plos One 7, no. 5 (January 2012): e36210. https://doi.org/10.1371/journal.pone.0036210.Full Text
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Dayan, Jonathan, Nickolay Voronin, Fan Gong, Tai-ping Sun, Peter Hedden, Hillel Fromm, and Roni Aloni. “Leaf-induced gibberellin signaling is essential for internode elongation, cambial activity, and fiber differentiation in tobacco stems.” The Plant Cell 24, no. 1 (January 2012): 66–79. https://doi.org/10.1105/tpc.111.093096.Full Text
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Yang, D. L., J. Yao, C. S. Mei, X. H. Tong, L. J. Zeng, Q. Li, L. T. Xiao, et al. “Plant hormone jasmonate prioritizes defense over growth by interfering with gibberellin signaling cascade.” Pnas 109 (2012): E1192.
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Sun, Tai-Ping. “The molecular mechanism and evolution of the GA-GID1-DELLA signaling module in plants.” Current Biology : Cb 21, no. 9 (May 2011): R338–45. https://doi.org/10.1016/j.cub.2011.02.036.Full Text
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Zhang, Z. L., M. Ogawa, C. M. Fleet, R. Zentella, J. Hu, J. O. Heo, J. Lim, Y. Kamiya, S. Yamaguchi, and T. P. Sun. “Scarecrow-like 3 promotes gibberellin signaling by antagonizing master growth repressor DELLA in Arabidopsis.” Proceedings of the National Academy of Sciences of the United States of America 108, no. 5 (February 2011): 2160–65. https://doi.org/10.1073/pnas.1012232108.Full Text
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Zhang, Z. L., M. Ogawa, C. M. Fleet, R. Zentella, J. Hu, J. -. O. Heo, J. Lim, Y. Kamiya, S. Yamaguchi, and T. -. P. Sun. “SCARECROW-LIKE 3 promotes gibberellin signaling by antagonizing DELLA in Arabidopsis.” Pnas 108 (2011): 2160–65.
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Sun, Tai-ping. “Gibberellin-GID1-DELLA: a pivotal regulatory module for plant growth and development.” Plant Physiology 154, no. 2 (October 2010): 567–70. https://doi.org/10.1104/pp.110.161554.Full Text
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Gilkerson, Jonathan, Jianhong Hu, Jessica Brown, Alexander Jones, Tai-ping Sun, and Judy Callis. “Isolation and characterization of cul1-7, a recessive allele of CULLIN1 that disrupts SCF function at the C terminus of CUL1 in Arabidopsis thaliana.” Genetics 181, no. 3 (March 2009): 945–63. https://doi.org/10.1534/genetics.108.097675.Full Text
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Murase, Kohji, Yoshinori Hirano, Tai-ping Sun, and Toshio Hakoshima. “Gibberellin-induced DELLA recognition by the gibberellin receptor GID1.” Nature 456, no. 7221 (November 2008): 459–63. https://doi.org/10.1038/nature07519.Full Text
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Ariizumi, Tohru, Kohji Murase, Tai-Ping Sun, and Camille M. Steber. “Proteolysis-independent downregulation of DELLA repression in Arabidopsis by the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1.” The Plant Cell 20, no. 9 (September 2008): 2447–59. https://doi.org/10.1105/tpc.108.058487.Full Text
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Hu, Jianhong, Melissa G. Mitchum, Neel Barnaby, Belay T. Ayele, Mikihiro Ogawa, Edward Nam, Wei-Chu Lai, et al. “Potential sites of bioactive gibberellin production during reproductive growth in Arabidopsis.” The Plant Cell 20, no. 2 (February 2008): 320–36. https://doi.org/10.1105/tpc.107.057752.Full Text
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Silverstone, Aron L., Tong-Seung Tseng, Stephen M. Swain, Alyssa Dill, Sun Yong Jeong, Neil E. Olszewski, and Tai-Ping Sun. “Functional analysis of SPINDLY in gibberellin signaling in Arabidopsis.” Plant Physiology 143, no. 2 (February 2007): 987–1000. https://doi.org/10.1104/pp.106.091025.Full Text
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Griffiths, J., K. Murase, I. Rieu, R. Zentella, Z. L. Zhang, S. J. Powers, F. Gong, et al. “Erratum: Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis (Plant Cell (2006) 18, (3399-3414)).” Plant Cell 19, no. 2 (January 1, 2007): 726. https://doi.org/10.1105/tpc.107.190261.Full Text
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Oh, D., D. E, D. Yamaguchi, D. S, D. Hu, D. J, D. Yusuke, et al. “PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds.” Plant Cell 19 (2007): 1192–1208.
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Zentella, Charles M., Charles M. R, Charles M. Zhang, Charles M. Z-L, Charles M. Park, Charles M. M, Stephen G. Thomas, et al. “Global Analysis of DELLA Direct Targets in Early Gibberellin Signaling in Arabidopsis.” Plant Cell 19 (2007): 3037–57.
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Griffiths, J., K. Murase, I. Rieu, R. Zentella, Z. L. Zhang, S. J. Powers, F. Gong, et al. “Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis.” The Plant Cell 18, no. 12 (December 2006): 3399–3414.
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Seo, Mitsunori, Atsushi Hanada, Ayuko Kuwahara, Akira Endo, Masanori Okamoto, Yukika Yamauchi, Helen North, et al. “Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism.” The Plant Journal : For Cell and Molecular Biology 48, no. 3 (November 2006): 354–66. https://doi.org/10.1111/j.1365-313x.2006.02881.x.Full Text
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Mitchum, Melissa G., Shinjiro Yamaguchi, Atsushi Hanada, Ayuko Kuwahara, Yasushi Yoshioka, Tomohiko Kato, Satoshi Tabata, Yuji Kamiya, and Tai-Ping Sun. “Distinct and overlapping roles of two gibberellin 3-oxidases in Arabidopsis development.” The Plant Journal : For Cell and Molecular Biology 45, no. 5 (March 2006): 804–18. https://doi.org/10.1111/j.1365-313x.2005.02642.x.Full Text
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Muangprom, Amorntip, Stephen G. Thomas, Tai-Ping Sun, and Thomas C. Osborn. “A novel dwarfing mutation in a green revolution gene from Brassica rapa.” Plant Physiology 137, no. 3 (March 2005): 931–38. https://doi.org/10.1104/pp.104.057646.Full Text
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Fleet, Christine M., and Tai-ping Sun. “A DELLAcate balance: the role of gibberellin in plant morphogenesis.” Current Opinion in Plant Biology 8, no. 1 (February 2005): 77–85. https://doi.org/10.1016/j.pbi.2004.11.015.Full Text
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Feng, Suhua, Yunping Shen, James A. Sullivan, Vicente Rubio, Yue Xiong, Tai-ping Sun, and Xing Wang Deng. “Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation.” The Plant Cell 16, no. 7 (July 2004): 1870–82. https://doi.org/10.1105/tpc.021949.Full Text
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Dill, Alyssa, Stephen G. Thomas, Jianhong Hu, Camille M. Steber, and Tai-Ping Sun. “The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation.” The Plant Cell 16, no. 6 (June 2004): 1392–1405. https://doi.org/10.1105/tpc.020958.Full Text
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Thomas, Stephen G., and Tai-ping Sun. “Update on gibberellin signaling. A tale of the tall and the short.” Plant Physiology 135, no. 2 (June 2004): 668–76. https://doi.org/10.1104/pp.104.040279.Full Text
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Tyler, Ludmila, Stephen G. Thomas, Jianhong Hu, Alyssa Dill, Jose M. Alonso, Joseph R. Ecker, and Tai-Ping Sun. “Della proteins and gibberellin-regulated seed germination and floral development in Arabidopsis.” Plant Physiology 135, no. 2 (June 2004): 1008–19. https://doi.org/10.1104/pp.104.039578.Full Text
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Dill, A., S. G. Thomas, J. Hu, C. M. Steber, and T. -. P. Sun. “The Arabidopsis F-Box Protein SLEEPY1 Targets GA Signaling Repressors for GA-Induced Degradation.” Plant Cell 16 (2004): 1392–1405.
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Sun, Tai-Ping, and Frank Gubler. “Molecular mechanism of gibberellin signaling in plants.” Annual Review of Plant Biology 55 (January 2004): 197–223. https://doi.org/10.1146/annurev.arplant.55.031903.141753.Full Text
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Fleet, Christine M., Shinjiro Yamaguchi, Atsushi Hanada, Hiroshi Kawaide, Charles J. David, Yuji Kamiya, and Tai-Ping Sun. “Overexpression of AtCPS and AtKS in Arabidopsis confers increased ent-kaurene production but no increase in bioactive gibberellins.” Plant Physiology 132, no. 2 (June 2003): 830–39. https://doi.org/10.1104/pp.103.021725.Full Text
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McGinnis, Karen M., Stephen G. Thomas, Jonathan D. Soule, Lucia C. Strader, Janice M. Zale, Tai-ping Sun, and Camille M. Steber. “The Arabidopsis SLEEPY1 gene encodes a putative F-box subunit of an SCF E3 ubiquitin ligase.” The Plant Cell 15, no. 5 (May 2003): 1120–30. https://doi.org/10.1105/tpc.010827.Full Text
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McGinnis, C., K. M, K. Thomas, S. G, S. Soule, J. D, J. Stader, et al. “The GA-response gene SLEEPY1 (SLY1) is a putative F-box subunit of an SCF E3 ubiquitin ligase.” Plant Cell 15 (2003): 1120–30.
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Chang, C. -. W., and T. -. P. Sun. “Characterization of cis-regulatory regions responsible for developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana.” Plant Mol. Biol. 49 (2002): 579–89.
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Olszewski, Neil, Tai-Ping Sun, and Frank Gubler. “Gibberellin signaling: biosynthesis, catabolism, and response pathways.” The Plant Cell 14 Suppl (January 2002): S61–80. https://doi.org/10.1105/tpc.010476.Full Text
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Dill, A., H. S. Jung, and T. P. Sun. “The DELLA motif is essential for gibberellin-induced degradation of RGA.” Proceedings of the National Academy of Sciences of the United States of America 98, no. 24 (November 2001): 14162–67. https://doi.org/10.1073/pnas.251534098.Full Text
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Yamaguchi, S., Y. Kamiya, and T. Sun. “Distinct cell-specific expression patterns of early and late gibberellin biosynthetic genes during Arabidopsis seed germination.” The Plant Journal : For Cell and Molecular Biology 28, no. 4 (November 2001): 443–53. https://doi.org/10.1046/j.1365-313x.2001.01168.x.Full Text
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Dill, A., and T. Sun. “Synergistic derepression of gibberellin signaling by removing RGA and GAI function in Arabidopsis thaliana.” Genetics 159, no. 2 (October 2001): 777–85. https://doi.org/10.1093/genetics/159.2.777.Full Text
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Silverstone, A. L., H. S. Jung, A. Dill, H. Kawaide, Y. Kamiya, and T. P. Sun. “Repressing a repressor: gibberellin-induced rapid reduction of the RGA protein in Arabidopsis.” The Plant Cell 13, no. 7 (July 2001): 1555–66. https://doi.org/10.1105/tpc.010047.Full Text
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Sun, T. “Gibberellin signal transduction.” Current Opinion in Plant Biology 3, no. 5 (October 2000): 374–80. https://doi.org/10.1016/s1369-5266(00)00099-6.Full Text
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Silverstone, A. L., and T. Sun. “Gibberellins and the Green Revolution.” Trends in Plant Science 5, no. 1 (January 2000): 1–2. https://doi.org/10.1016/s1360-1385(99)01516-2.Full Text
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Yamaguchi, S., T. P. Sun, H. Kawaide, and Y. Kamiya. “The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis.” Plant Physiology 116, no. 4 (April 1998): 1271–78. https://doi.org/10.1104/pp.116.4.1271.Full Text
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Silverstone, A. L., C. N. Ciampaglio, and T. Sun. “The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway.” The Plant Cell 10, no. 2 (February 1998): 155–69. https://doi.org/10.1105/tpc.10.2.155.Full Text
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Yamaguchi, C. E., C. E. S, C. E. Smith, M. W, M. Brown, R. G. S, R. G. Kamiya, R. G. Y, R. G. Sun, and R. G. T-p. “Phytochrome regulation and differential expression of gibberellin 3b-hydroxylase genes in germinating Arabidopsis seeds.” Plant Cell 10 (1998): 2115–26.
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Sun, T. P., and Y. Kamiya. “Regulation and cellular localization of ent-kaurene synthesis.” Physiologia Plantarum 101, no. 4 (December 1, 1997): 701–8. https://doi.org/10.1034/j.1399-3054.1997.1010405.x.Full Text
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Silverstone, A. L., C. Chang, E. Krol, and T. P. Sun. “Developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana.” The Plant Journal : For Cell and Molecular Biology 12, no. 1 (July 1997): 9–19. https://doi.org/10.1046/j.1365-313x.1997.12010009.x.Full Text
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Silverstone, A. L., P. Y. Mak, E. C. Martínez, and T. P. Sun. “The new RGA locus encodes a negative regulator of gibberellin response in Arabidopsis thaliana.” Genetics 146, no. 3 (July 1997): 1087–99. https://doi.org/10.1093/genetics/146.3.1087.Full Text
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Ait-Ali, T., S. M. Swain, J. B. Reid, T. Sun, and Y. Kamiya. “The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A.” The Plant Journal : For Cell and Molecular Biology 11, no. 3 (March 1997): 443–54. https://doi.org/10.1046/j.1365-313x.1997.11030443.x.Full Text
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Sun, T. P., and Y. Kamiya. “The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis.” The Plant Cell 6, no. 10 (October 1994): 1509–18. https://doi.org/10.1105/tpc.6.10.1509.Full Text
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Sun, Y., Y. T-p, Y. Goodman, H. M, H. Ausubel, and F. M. “Cloning the Arabidopsis GA1 locus by genomic subtraction.” Plant Cell 4 (1992): 119–28.
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Russel, M., H. Whirlow, T. P. Sun, and R. E. Webster. “Low-frequency infection of F- bacteria by transducing particles of filamentous bacteriophages.” Journal of Bacteriology 170, no. 11 (November 1988): 5312–16. https://doi.org/10.1128/jb.170.11.5312-5316.1988.Full Text
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Sun, T. P., and R. E. Webster. “Nucleotide sequence of a gene cluster involved in entry of E colicins and single-stranded DNA of infecting filamentous bacteriophages into Escherichia coli.” Journal of Bacteriology 169, no. 6 (June 1987): 2667–74. https://doi.org/10.1128/jb.169.6.2667-2674.1987.Full Text
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Sun, T. P., and R. E. Webster. “fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB.” Journal of Bacteriology 165, no. 1 (January 1986): 107–15. https://doi.org/10.1128/jb.165.1.107-115.1986.Full Text
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Book Sections
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Sun, T. P. “Gibberellin signal transduction in stem elongation & leaf growth.” In Plant Hormones: Biosynthesis, Signal Transduction, Action!, 308–28, 2010. https://doi.org/10.1007/978-1-4020-2686-7_15.Full Text
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Sun, Tai-ping. “Gibberellin Metabolism, Perception and Signaling Pathways in Arabidopsis.” In The Arabidopsis Book, Vol. 6. BioOne Digital Library, 2008. https://doi.org/10.1199/tab.0103.Full Text
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- Teaching & Mentoring
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Recent Courses
- BIOLOGY 213D: Cell Signaling and Diseases 2023
- BIOLOGY 417S: Genetic Engineering and Biotechnology 2023
- BIOLOGY 493: Research Independent Study 2023
- BIOLOGY 791T: Tutorial 2023
- SCISOC 417S: Genetic Engineering and Biotechnology 2023
- BIOLOGY 213D: Cell Signaling and Diseases 2022
- BIOLOGY 293: Research Independent Study 2022
- BIOLOGY 417S: Genetic Engineering and Biotechnology 2022
- BIOLOGY 493: Research Independent Study 2022
- SCISOC 417S: Genetic Engineering and Biotechnology 2022
- BIOLOGY 213D: Cell Signaling and Diseases 2021
- BIOLOGY 417S: Genetic Engineering and Biotechnology 2021
- BIOLOGY 791T: Tutorial 2021
- SCISOC 417S: Genetic Engineering and Biotechnology 2021
- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- Plenary Speaker, Regulatory Mechanism of Master Growth Repressor DELLA Signaling in Arabidopsis. International Gibberellins 2019 Meeting. June 2019 2019
- Invited Talk, Regulation of Nuclear Transcription Factors by a Novel Interplay Between Posttranslational O-Fucosylation and O-GlcNAcylation. Gordon Research Conference on Glycobiology. March 2019 2019
- Silver Medal Lecture. June 18, 2013 2013
- Gordon Conference-- Plant Molecular Biology. July 1, 2012 2012
- GA-GID1-DELLA: A pivotal regulatory module for plant growth and development. September 1, 2011 2011
- The Role of GA-GID1-DELLA Signaling Module in Plant Growth and Development. June 1, 2011 2011
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Service to the Profession
- Frontier Research Grant Panel. European Research Council. 2017 2017
- Reviewing Editor, 2005-present. Plant Cell. 2015 2015
- Guest Editor, 2011-present. PNAS. 2011 - 2020 2011 - 2020
- NCBC Plant Molecular Biology Consortium, Chair. 2010 - 2012 2010 - 2012
- Editorial Board. Plant Cell Physiology. 2007 - 2010 2007 - 2010
- Advisory Board. Institute of Plant and Microbial Biology, Academia Sinica. 2004 - 2016 2004 - 2016
- Contributing Faculty Member, 2003-present . FACULTY OF 1000 BIOLOGY. 2003 - 2020 2003 - 2020
- Council Member. International Plant Growth Substances Association. 2001 - 2007 2001 - 2007
- Monitoring Editor. Plant Physiology. 2000 - 2005 2000 - 2005
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