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Talal Imad Mousallem

Associate Professor of Pediatrics
Pediatrics, Allergy and Immunology
Dept of Pediatrics, Box 2644, Durham, NC 27710
Dept of Pediatrics, Box 2644, Durham, NC 27710

Overview


I am an allergist and immunologist who cares for children. I manage patients with primary immunodeficiency and different allergic diseases. This includes managing patients with recurrent infections, allergic rhinitis, asthma, food allergy, drug allergy, stinging insect hypersensitivity, urticaria/ angioedema, and allergic skin disease. I also see patients with abnormal severe combined immunodeficiency newborn screen results.

Current Appointments & Affiliations


Associate Professor of Pediatrics · 2021 - Present Pediatrics, Allergy and Immunology, Pediatrics

Recent Publications


Outcomes Following Matched Sibling Donor Transplantation for Severe Combined Immunodeficiency: A Report from the PIDTC.

Journal Article Blood Adv · November 25, 2025 The Primary Immune Deficiency Treatment Consortium (PIDTC) performed a retrospective analysis of 133 patients with severe combined immunodeficiency (SCID) receiving matched sibling donor (MSD) hematopoietic cell transplantation (HCT) between 1980 and 2023 at ... Full text Link to item Cite

Clinicopathologic Features and the Spectrum of Myelokathexis in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Syndrome.

Journal Article Lab Invest · August 2025 Warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome is a rare primary immunodeficiency disorder predominantly caused by germline CXCR4 variants. Bone marrow (BM) evaluation showing myelokathexis helps to establish the diagnosis of WHIM ... Full text Link to item Cite

Multi-Year Registry Study of Elapegademase Treatment in Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) Requiring Enzyme Replacement Therapy.

Journal Article J Clin Immunol · March 27, 2025 PURPOSE: The safety and tolerability of elapegademase (elapegademase-lvlr; Revcovi®) a PEGylated recombinant adenosine deaminase (ADA), were demonstrated in two Phase 3 clinical trials in the U.S. and Japan in patients with ADA-deficient severe combined im ... Full text Link to item Cite
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Recent Grants


Developing a National Registry for Female Carriers of X-linked Chronic Granulomatous Disease: Improving Recognition, Diagnosis, and Treatment

ResearchCollaborator · Awarded by American College of Allergy, Asthma & Immunology · 2024 - 2026

Primary Immune Deficiency Treatment Consortium

ResearchPrincipal Investigator · Awarded by University of California - San Francisco · 2014 - 2025

Severe Combined Immunodeficiency (SCID) Screening and Education

ResearchPrincipal Investigator · Awarded by University of California - San Francisco · 2023 - 2023

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Education, Training & Certifications


American University of Beirut (Lebanon) · 2003 M.D.