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James Enlou Tcheng

Professor of Medicine
Medicine, Cardiology
Duke Box 2708, Durham, NC 27710
Suite 403 Hock Plaza, 2424 Erwin Road, Durham, NC
Office hours Normal business hours.  

Overview


In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease, clinical informatics, artificial intelligence, and information technology systems. 

I have conducted and participated in numerous clinical trials, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, ELECT, and SUPPORT Trials.

My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.

My current focus is in clinical informatics, including initiatives spanning professional societies, regulatory and other government agencies, industry, and non-governmental organizations to develop clinical data standards, interoperability solutions, and to integrate structured reporting into clinical workflows. This includes harmonizing the clinical definitions of cardiovascular concepts across academia, regulatory agencies, the life sciences industry, professional societies, and standards organizations, to improve the capture, communication, interoperability, and analysis of healthcare information.

Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials, clinical informatics.

Current Appointments & Affiliations


Professor of Medicine · 2007 - Present Medicine, Cardiology, Medicine
Associate Dean for Academic Appointments · 2022 - Present School of Medicine
Professor of Family Medicine and Community Health · 2008 - Present Family Medicine and Community Health, Clinical Science Departments

Recent Publications


Translating proof-of-concept for platelet slip into improved antithrombotic therapeutic regimens.

Journal Article Platelets · December 2024 Platelets are central to thrombosis. Research at the intersection of biological and physical sciences provides proof-of-concept for shear rate-dependent platelet slip at vascular stenosis and near device surfaces. Platelet slip extends the observed biologi ... Full text Link to item Cite

The high price of equity in pulse oximetry: A cost evaluation and need for interim solutions.

Journal Article PLOS Digit Health · September 2024 Disparities in pulse oximetry accuracy, disproportionately affecting patients of color, have been associated with serious clinical outcomes. Although many have called for pulse oximetry hardware replacement, the cost associated with this replacement is not ... Full text Link to item Cite

Assessing Real-World Data From Electronic Health Records for Health Technology Assessment: The SUITABILITY Checklist: A Good Practices Report of an ISPOR Task Force.

Journal Article Value Health · June 2024 This ISPOR Good Practices report provides a framework for assessing the suitability of electronic health records data for use in health technology assessments (HTAs). Although electronic health record (EHR) data can fill evidence gaps and improve decisions ... Full text Link to item Cite
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Recent Grants


Core variable Assessment Towards a NatIonal evaluation Program (CATNIP) - Subcontract with Weill Cornell

ResearchCo Investigator · Awarded by Weill Cornell Medicine · 2020 - 2021

PCI QA Review

ResearchPrincipal Investigator · Awarded by The Foundation of FirstHealth · 2019 - 2020

Building UDI Into Longitudinal Data for Medical Device Evaluation (BUILD)

ResearchPrincipal Investigator · Awarded by Mercy Health · 2018 - 2019

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Education, Training & Certifications


Johns Hopkins University · 1982 M.D.