Overview
In addition to my clinical responsibilities as an interventional cardiologist, my research interests include the study of antithrombotic therapies in cardiovascular disease, clinical informatics, artificial intelligence, and information technology systems.
I have conducted and participated in numerous clinical trials, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, ELECT, and SUPPORT Trials.
My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.
My current focus is in clinical informatics, including initiatives spanning professional societies, regulatory and other government agencies, industry, and non-governmental organizations to develop clinical data standards, interoperability solutions, and to integrate structured reporting into clinical workflows. This includes harmonizing the clinical definitions of cardiovascular concepts across academia, regulatory agencies, the life sciences industry, professional societies, and standards organizations, to improve the capture, communication, interoperability, and analysis of healthcare information.
Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials, clinical informatics.
I have conducted and participated in numerous clinical trials, including the EPIC, PROLOG, EPILOG, EPISTENT, IMPACT, IMPACT II, TOTAL, PRIDE, ESPRIT, MEND-1, ELECT, and SUPPORT Trials.
My areas of expertise are an outgrowth of my clinical research, and includes use of the new antiplatelet therapeutics in the treatment of coronary artery disease; treatment of unstable angina and acute myocardial infarction; quality assurance and quality improvement; application of informatics and information technology to the delivery of care; and the application of excimer laser coronary angioplasty in the treatment of coronary artery disease.
My current focus is in clinical informatics, including initiatives spanning professional societies, regulatory and other government agencies, industry, and non-governmental organizations to develop clinical data standards, interoperability solutions, and to integrate structured reporting into clinical workflows. This includes harmonizing the clinical definitions of cardiovascular concepts across academia, regulatory agencies, the life sciences industry, professional societies, and standards organizations, to improve the capture, communication, interoperability, and analysis of healthcare information.
Key words: angioplasty, excimer laser, platelet glycoproteins, computers, clinical trials, clinical informatics.
Current Appointments & Affiliations
Professor of Medicine
·
2007 - Present
Medicine, Cardiology,
Medicine
Associate Dean for Academic Appointments
·
2022 - Present
School of Medicine
Professor of Family Medicine and Community Health
·
2008 - Present
Family Medicine and Community Health,
Clinical Science Departments
Recent Publications
Evaluating the potential of fast healthcare interoperability resources for clinical registry data submission.
Journal Article J Am Med Inform Assoc · March 9, 2026 OBJECTIVE: We conducted the Clinical Registry Extraction and Data Submission (CREDS) project to evaluate the readiness of HL7 Fast Healthcare Interoperability Resources (FHIR) for provisioning data from health information systems for the American College o ... Full text Link to item CiteBuilding Real-World Evidence Infrastructure to Improve Health and Healthcare in the United States: Part II-How Coordinated Registry Networks Operate Like Systemic Coordinated Inter-Organizational Networks.
Journal Article Int J Transl Med Res Public Health · December 20, 2025 BACKGROUND AND OBJECTIVE: Coordinated Registry Networks (CRNs) are networks of healthcare partners that create and utilize information from clinical society registries and other sources to drive evidence-based improvements in healthcare. In Part I of this ... Full text Link to item CiteBuilding Real-World Evidence Infrastructure to Improve Health and Healthcare in the United States: Part I-Coordinated Registry Networks and Systemic Coordinated Inter-Organizational Networks.
Journal Article Int J Transl Med Res Public Health · December 20, 2025 BACKGROUND AND OBJECTIVE: Over the past decade substantial government and market-driven efforts focused on the use of real-world evidence (RWE) to improve healthcare decision-making. A successful strategy has been mounted by specialty societies and their r ... Full text Link to item CiteRecent Grants
Core variable Assessment Towards a NatIonal evaluation Program (CATNIP) - Subcontract with Weill Cornell
ResearchCo Investigator · Awarded by Weill Cornell Medicine · 2020 - 2021PCI QA Review
ResearchPrincipal Investigator · Awarded by The Foundation of FirstHealth · 2019 - 2020Building UDI Into Longitudinal Data for Medical Device Evaluation (BUILD)
ResearchPrincipal Investigator · Awarded by Mercy Health · 2018 - 2019View All Grants
Education
Johns Hopkins University ·
1982
M.D.