Selected Grants
Chemical Biology Strategies to Resolve Plasmodium Heat Shock Protein Function
ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028Development of Diagnostic/Therapeutic Agents Targeting Borrelia burgdorferi HtpG
ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2027Preclinical Development Of Novel Borrelia Sp. Targeting Therapeutic And Diagnostic Imaging Agents.
ResearchPrincipal Investigator · Awarded by Bay Area Lyme Foundation · 2021 - 2025Development of an oral targeted drug for treatment of bartonelloses
ResearchPrincipal Investigator · Awarded by Steven & Alexandra Cohen Foundation · 2021 - 2025Pharmacological Sciences Training Grant
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025Targeting heat shock protein 72 to improve renal function after transplantation
ResearchPrincipal Investigator · Awarded by University of Arkansas for Medical Sciences · 2021 - 2022Targeting Borrelia specific immune cell populations in vivo through expression of ectopically expressed Hsp90
ResearchPrincipal Investigator · Awarded by Bill & Marian Cook Foundation · 2019 - 2022Detection and Elimination of Oncogenic Signaling Networks in Pre-malignant and Malignant Cells with Magnetic Resonance Imaging
ResearchCo Investigator · Awarded by Department of Defense · 2012 - 2022Evaluating the Blood-Brain Barrier Bioavailability and in vivo Efficacy Potential of a Novel TAK1 Inhibitor Targeting Chronic Pain
ResearchPrincipal Investigator · Awarded by Eydis Bio Inc. · 2021 - 2022Pharmacokinetics and efficacy of SNX-5422 in suppressing SARS-CoV-2 viral loads in Golden Syrian Year 1 Hamsters
ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2021 - 2022Co-crystalization of inducible Heat shock Protein 70 with the inhibitor HS-72 and structural analogs.
ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2018 - 2021Improving the Oral Bioavailability and In vivo Efficacy of the TAK 1 Inhibitor, Takinib.
ResearchPrincipal Investigator · Awarded by Eydis Bio Inc. · 2019 - 2021An orally bioavailable broad-spectrum Hsp90 inhibitor (Hsp90i) therapy to suppress emerging Coronavirus (CoV) infections
ResearchInvestigator · Awarded by Good Ventures Foundation · 2020 - 2021Interdisciplinary Training Program in Lung Disease
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2009 - 2021Improving the Oral Bioavailability and in vivo efficacy of the TAK 1 inhibitor, Takinib.
ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2019 - 2021Organization and Function of Cellular Structure
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020Pharmacological Sciences Training Program
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020Pharmacology Industry Internships for Ph.D. Students
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2017 - 2019A novel strategy to see and treat breast cancer: translation to intra-operative breast margin assessment
ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2019Development of Tethered Hsp90 Inhibitors Carrying Radioiodinated Probes to Specifically Descriminate and Kill Malignant Breast Tumor Cells
ResearchPrincipal Investigator · Awarded by Department of Defense · 2015 - 2019Discovery of novel liver host targets for malaria treatment
FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2016 - 2019Literature search of clinical trials studies on Hsp90 inhibitors
ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2017 - 2018Co-crystallization of Hsp70i and the inhibitor HS-72
ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2017 - 2018Targeting the synthetic essential kinases of breast cancers
ResearchCo Investigator · Awarded by Department of Defense · 2015 - 2018Preclinical Development of Novel HSP90 Inhibitors for the Prevention and Treatment of Chikungunya Virus Infections
ResearchPrincipal Investigator · Awarded by National University of Singapore · 2014 - 2016The Duke Multidisciplinary Training Program in Pediatric Lung Disease
Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2010 - 2016Discovery and development of broad spectrum anti-flaviviral drugs
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2010 - 2016A Novel Method to Stop HIV Replication: Inhibition of Human Purine-Utilizing Proteins
ResearchPrincipal Investigator · Awarded by Ohio State University · 2010 - 2014Molecular mechanisms of chemoresistance in breast cancer
ResearchConsultant · Awarded by National Institutes of Health · 2010 - 2012Calcium desensitization in Smooth Muscle.
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2010 - 2011Maturation of Normal & Sensitized Airway Contractility
ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2011Proteome Mining as a Predictive Tool of Drug Toxicity
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2010G Protein Involvement in Oncogenesis and Metastasis
ResearchConsultant · Awarded by National Institutes of Health · 2004 - 2009Pseudomonas Invasion and the Role of Caveolin-2
ResearchCollaborator · Awarded by National Institutes of Health · 2006 - 2009Regulation of smooth muscle-myosin phosphatase 1 kinase
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2008Protein Phosphatase 1 Regulation by Multiple Subunits
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2006Graduate Training Program in Pharmacological Sciences.
Inst. Training Prgm or CMECo-Principal Investigator · Awarded by National Institutes of Health · 1975 - 2005Proteomic/Genetic Approaches to Monoamine Transporters
ResearchCo-Mentor · Awarded by National Institutes of Health · 2003 - 2004Activation of critical gene sets for spinal axon repair
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2001 - 2004External Relationships
- ClaymoreBio LLC
- Eydis Bio, Inc.
- Open philanthropy.org
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.