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Timothy Arthur James Haystead

Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
Duke Box 3813, Durham, NC 27710
C 118 LSRC, Durham, NC 27708

Selected Grants


Chemical Biology Strategies to Resolve Plasmodium Heat Shock Protein Function

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028

Development of an oral targeted drug for treatment of bartonelloses

ResearchPrincipal Investigator · Awarded by Steven & Alexandra Cohen Foundation · 2021 - 2025

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Preclinical Development Of Novel Borrelia Sp. Targeting Therapeutic And Diagnostic Imaging Agents.

ResearchPrincipal Investigator · Awarded by Bay Area Lyme Foundation · 2021 - 2024

Targeting heat shock protein 72 to improve renal function after transplantation

ResearchPrincipal Investigator · Awarded by University of Arkansas for Medical Sciences · 2021 - 2023

Chemical Biology Strategies to Resolve Plasmodium Heat Shock Protein Function

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028

Development of an oral targeted drug for treatment of bartonelloses

ResearchPrincipal Investigator · Awarded by Steven & Alexandra Cohen Foundation · 2021 - 2025

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Preclinical Development Of Novel Borrelia Sp. Targeting Therapeutic And Diagnostic Imaging Agents.

ResearchPrincipal Investigator · Awarded by Bay Area Lyme Foundation · 2021 - 2024

Targeting heat shock protein 72 to improve renal function after transplantation

ResearchPrincipal Investigator · Awarded by University of Arkansas for Medical Sciences · 2021 - 2023

Targeting Borrelia specific immune cell populations in vivo through expression of ectopically expressed Hsp90

ResearchPrincipal Investigator · Awarded by Bill & Marian Cook Foundation · 2019 - 2022

Pharmacokinetics and efficacy of SNX-5422 in suppressing SARS-CoV-2 viral loads in Golden Syrian Year 1 Hamsters

ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2021 - 2022

Co-crystalization of inducible Heat shock Protein 70 with the inhibitor HS-72 and structural analogs.

ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2018 - 2021

Improving the Oral Bioavailability and In vivo Efficacy of the TAK 1 Inhibitor, Takinib.

ResearchPrincipal Investigator · Awarded by Eydis Bio Inc. · 2019 - 2021

Interdisciplinary Training Program in Lung Disease

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2009 - 2021

Improving the Oral Bioavailability and in vivo efficacy of the TAK 1 inhibitor, Takinib.

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2019 - 2021

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

Pharmacology Industry Internships for Ph.D. Students

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2017 - 2019

A novel strategy to see and treat breast cancer: translation to intra-operative breast margin assessment

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2019

Discovery of novel liver host targets for malaria treatment

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2016 - 2019

Literature search of clinical trials studies on Hsp90 inhibitors

ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2017 - 2018

Co-crystallization of Hsp70i and the inhibitor HS-72

ResearchPrincipal Investigator · Awarded by Open Philanthropy Project · 2017 - 2018

Targeting the synthetic essential kinases of breast cancers

ResearchCo Investigator · Awarded by Department of Defense · 2015 - 2018

Preclinical Development of Novel HSP90 Inhibitors for the Prevention and Treatment of Chikungunya Virus Infections

ResearchPrincipal Investigator · Awarded by National University of Singapore · 2014 - 2016

The Duke Multidisciplinary Training Program in Pediatric Lung Disease

Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2010 - 2016

Discovery and development of broad spectrum anti-flaviviral drugs

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2010 - 2016

A Novel Method to Stop HIV Replication: Inhibition of Human Purine-Utilizing Proteins

ResearchPrincipal Investigator · Awarded by Ohio State University · 2010 - 2014

Molecular mechanisms of chemoresistance in breast cancer

ResearchConsultant · Awarded by National Institutes of Health · 2010 - 2012

Calcium desensitization in Smooth Muscle.

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2010 - 2011

Maturation of Normal & Sensitized Airway Contractility

ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2011

Proteome Mining as a Predictive Tool of Drug Toxicity

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2010

G Protein Involvement in Oncogenesis and Metastasis

ResearchConsultant · Awarded by National Institutes of Health · 2004 - 2009

Pseudomonas Invasion and the Role of Caveolin-2

ResearchCollaborator · Awarded by National Institutes of Health · 2006 - 2009

Regulation of smooth muscle-myosin phosphatase 1 kinase

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2008

Protein Phosphatase 1 Regulation by Multiple Subunits

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2006

Graduate Training Program in Pharmacological Sciences.

Inst. Training Prgm or CMECo-Principal Investigator · Awarded by National Institutes of Health · 1975 - 2005

Proteomic/Genetic Approaches to Monoamine Transporters

ResearchCo-Mentor · Awarded by National Institutes of Health · 2003 - 2004

Activation of critical gene sets for spinal axon repair

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2001 - 2004

External Relationships


  • ClaymoreBio LLC
  • Eydis Bio, Inc.
  • Open philanthropy.org

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.