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Tobias Straube

Assistant Professor of Pediatrics
Pediatrics, Critical Care Medicine
2301 Erwin Road, Suite 5260Y, Durham, NC 27710
2301 Erwin Road, Suite 5260Y, Durham, NC 27710

Selected Publications


Optimization of the IntraVascular Oxygenator Catheter Using Angular Oscillation.

Journal Article Ann Biomed Eng · March 2024 We demonstrate a methodology which both improves oxygen transport and reduces or eliminates bubble formation in a novel hyperbaric membrane oxygenator catheter model system. Angular oscillations were introduced to a bundle of hollow fiber membranes (HFMs) ... Full text Link to item Cite

Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts.

Journal Article Respir Care · April 2022 Acute respiratory failure with inadequate oxygenation and/or ventilation is a common reason for ICU admission in children and adults. Despite the morbidity and mortality associated with acute respiratory failure, few proven treatment options exist beyond i ... Full text Link to item Cite

Development of a novel intravascular oxygenator catheter: Oxygen mass transfer properties across nonporous hollow fiber membranes.

Journal Article Biotechnol Bioeng · January 2021 Despite hypoxic respiratory failure representing a large portion of total hospitalizations and healthcare spending worldwide, therapeutic options beyond mechanical ventilation are limited. We demonstrate the technical feasibility of providing oxygen to a b ... Full text Link to item Cite

Ultrasonic bubble detection and tracking using spatial coherence and motion modeling

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2021 Limited options exist to improve oxygenation in patients with acute hypoxic respiratory failure. We are developing an intravascular oxygenator catheter capable of delivering a clinically significant amount of oxygen directly into the bloodstream of patient ... Full text Cite

Extracorporeal Membrane Oxygenation for Hemodynamic Support.

Journal Article Clin Perinatol · September 2020 Extracorporeal membrane oxygenation was first successfully achieved in 1975 in a neonate with meconium aspiration. Neonatal extracorporeal membrane oxygenation has expanded to include hemodynamic support in cardiovascular collapse before and after cardiac ... Full text Link to item Cite