Ganesan Vaidyanathan | Scholars@Duke

Ganesan Vaidyanathan
Professor in Radiology

Dr. Vaidyanathan is a professor in the Department of Radiology. He is a member of the Nuclear Medicine track of the Medical Physics Graduate Program. His research involves development of radiopharmaceuticals especially for oncologic applications. Some of the projects he is involved in are given below.

I. New methods of radiohalogenating antibodies and its variants

a) Development of newer residualizing agents for the radiohalogenation of internalizing monoclonal antibodies.

b) Development of fluorine-18 labeled residualizing agents for labeling nanobodies.

c) Pre-targeting approach via bioorthogonal chemistry for in vivo labeling of antibodies and nanobodies with ¹⁸F and ²¹¹At.

d) Methods to label antibodies pre-conjugated with a prosthetic group of the tin precursor of residualizing agents.

e) Multimodal prosthetic groups for labeling antibodies and peptides with multiple radioisotopes.

II. MIBG Analogs for PET imaging

Radioiodinated MIBG is used in the diagnosis of the pathophysiology of the heart as well as neuroendocrine tumors such as neuroblastoma (NB). Design and development of newer fluorine-18 labeled MIBG analogues useful in the PET imaging of NB as well as that of myocardial diseases.

III. Noninvasive Imaging of Alkylguanine-DNA alkyltransferase (AGT)

AGT is a DNA repair protein and is primarily responsible for drug resistance in alkylator chemotherapy. An inverse correlation has been established between the tumor AGT content and the therapeutic outcome. The amount of AGT varies from tumor to tumor and within a group of patients of similar cancer. Thus, it is important to quantify tumor AGT of individual patients before administering alkylator chemotherapy. Our goal is to develop radiolabeled agents with which AGT can be quantified in a noninvasive manner by PET or SPECT imaging.

IV. PSMA targeting for prostate cancer therapy

Development of At-211 labeled urea-based inhibitor of Prostate-specific membrane antigen.

Current Appointments & Affiliations

Professor in Radiology, Radiology, Clinical Science Departments 2018
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1989

Contact Information

161C Bryan Res Bldg, Durham, NC 27710
Box 3808 Med Ctr, Radiology, Durham, NC 27710
vaidy001@mc.duke.edu (919) 684-7811

Background
Education, Training, & Certifications
- Postdoctoral, College Of Pharmacy, University of Kentucky at Lexington 1987 - 1989
- Teaching Assistant, Chemistry Dept, University of Kentucky at Lexington 1983 - 1987
- Ph.D., University of Kentucky at Lexington 1987
Duke Appointment History
- Professor in Radiology, Radiology, Clinical Science Departments 2006 - 2018
- Research Professor in Radiology, Radiology, Clinical Science Departments 2005 - 2006
- Associate Research Professor in Radiology, Radiology, Clinical Science Departments 1998 - 2005
- Assistant Research Professor in Radiology, Radiology, Clinical Science Departments 1994 - 1998
Research
Selected Grants
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1985 - 2020
- Labeling nanobodies with 18F residualizing labels for HER2 specific PET imaging awarded by National Institutes of Health 2015 - 2020
- Cereius research agreement awarded by Cereius Inc. 2017 - 2019
- Development of Tethered Hsp90 Inhibitors Carrying Radioiodinated Probes to Specifically Discriminate and Kill Malignant awarded by Department of Defense 2015 - 2019
- Small Molecule PSMA-Targeted Alpha Therapy awarded by Johns Hopkins University 2014 - 2019
- Novel Radiohalogenation Strategies for Enhancing Imaging and Targeted Radiotherapy awarded by Memorial Sloan Kettering Cancer Center 2016 - 2018
- Development of a Targeted Radionuclide Therapy for Triple Negative Breast Cancer awarded by OncoTAb, Inc. 2016 - 2017
- Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
- Enhancing the efficacy of targeted radiotherapy for neuroblastoma awarded by Children's Hospital of Philadelphia 2013 - 2014
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Brain Tumors - Immunological and Biological Studies awarded by National Institutes of Health 2001 - 2013
- Small Animal PET / CT Molecular Imaging awarded by National Institutes of Health 2011 - 2012
- Radionuclide-based Molecular Imaging of the DNA Repair Protein AGT awarded by National Institutes of Health 2009 - 2011
- Astatine-211 Radiochemistry: The Development of Methodologies for High Activity Level Radio-Synthesis awarded by Department of Energy 2008 - 2010
- Research Training In Neuro-Oncology awarded by National Institutes of Health 2005 - 2010
- Imaging of O6-Alkylguianine-DNA Alkyltransferase awarded by National Institutes of Health 2002 - 2007
- Targeted Radiotherapeutics: Chemical and Biological Aspects awarded by Department of Energy 2004 - 2006
- Astatine-211 & Radioiodine Labeled Octreotide Conjugates awarded by National Institutes of Health 2001 - 2006
- Anti-Tenascin Antibody Constructs awarded by Department of Energy 1995 - 2005
- Molecular Imaging Center Planning Grant awarded by National Institutes of Health 2000 - 2004
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1999 - 2004
- MIBG Analogue Radiopharmaceuticals awarded by National Institutes of Health 1997 - 2003
- Brain Tumors--Immunological and Biological Studies awarded by National Institutes of Health 1976 - 2001
- Brain Tumors - Immunological And Biological Studies awarded by National Institutes of Health 1997 - 1999
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1994 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1993 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1985 - 1999
- Positron Emission Imaging Of Tumors Using Monoclonal Antib awarded by Department of Energy 1995 - 1998
- Migb And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1994 - 1998
- Mibg And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
- Mibg And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
- Migb And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
- Cancer And Leukemia Group B Statistical Center awarded by National Institutes of Health 1992 - 1993
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Zhou, Z, McDougald, D, Devoogdt, N, Zalutsky, MR, and Vaidyanathan, G. "Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios." Molecular Pharmaceutics (November 28, 2018). Full Text
  - Zhou, Z, Devoogdt, N, Zalutsky, MR, and Vaidyanathan, G. "An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker." Bioconjugate Chemistry (November 14, 2018). Full Text
  - Vaidyanathan, G, Kang, CM, McDougald, D, Minn, I, Brummet, M, Pomper, MG, and Zalutsky, MR. "Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors." Nuclear Medicine and Biology 62-63 (July 2018): 18-30. Full Text
  - Pruszynski, M, Kang, CM, Koumarianou, E, Vaidyanathan, G, and Zalutsky, MR. "d-Amino Acid Peptide Residualizing Agents for Protein Radioiodination: Effect of Aspartate for Glutamate Substitution." Molecules (Basel, Switzerland) 23, no. 5 (May 20, 2018). Full Text
  - Zhou, Z, Chitneni, SK, Devoogdt, N, Zalutsky, MR, and Vaidyanathan, G. "Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation." Bioorganic & Medicinal Chemistry 26, no. 8 (May 2018): 1939-1949. Full Text
  - Choi, J, Vaidyanathan, G, Koumarianou, E, Kang, CM, and Zalutsky, MR. "Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation." Nuclear Medicine and Biology 56 (January 2018): 10-20. Full Text Open Access Copy
  - Zhou, Z, Vaidyanathan, G, McDougald, D, Kang, CM, Balyasnikova, I, Devoogdt, N, Ta, AN, McNaughton, BR, and Zalutsky, MR. "Fluorine-18 Labeling of the HER2-Targeting Single-Domain Antibody 2Rs15d Using a Residualizing Label and Preclinical Evaluation." Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging 19, no. 6 (December 2017): 867-877. Full Text
  - Chin, BB, McDougald, D, Weitzel, DH, Hawk, T, Reiman, RE, Zalutsky, MR, and Vaidyanathan, G. "Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine." Current radiopharmaceuticals 10, no. 1 (January 2017): 41-50. Full Text Open Access Copy
  - Kiess, AP, Minn, I, Vaidyanathan, G, Hobbs, RF, Josefsson, A, Shen, C, Brummet, M, Chen, Y, Choi, J, Koumarianou, E, Baidoo, K, Brechbiel, MW, Mease, RC, Sgouros, G, Zalutsky, MR, and Pomper, MG. "(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 57, no. 10 (October 2016): 1569-1575. Full Text
  - Vaidyanathan, G, McDougald, D, Choi, J, Koumarianou, E, Weitzel, D, Osada, T, Lyerly, HK, and Zalutsky, MR. "Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET." Journal of nuclear medicine : official publication, Society of Nuclear Medicine 57, no. 6 (June 2016): 967-973. Full Text
  - Vaidyanathan, G, McDougald, D, Choi, J, Pruszynski, M, Koumarianou, E, Zhou, Z, and Zalutsky, MR. "N-Succinimidyl 3-((4-(4-[(18)F]fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate ([(18)F]SFBTMGMB): a residualizing label for (18)F-labeling of internalizing biomolecules." Organic & biomolecular chemistry 14, no. 4 (January 2016): 1261-1271. Full Text
  - Vaidyanathan, G, McDougald, D, Koumarianou, E, Choi, J, Hens, M, and Zalutsky, MR. "Synthesis and evaluation of 4-[18F]fluoropropoxy-3-iodobenzylguanidine ([18F]FPOIBG): A novel 18F-labeled analogue of MIBG." Nuclear medicine and biology 42, no. 8 (August 2015): 673-684. Full Text
  - Liu, Y, Ashton, JR, Moding, EJ, Yuan, H, Register, JK, Fales, AM, Choi, J, Whitley, MJ, Zhao, X, Qi, Y, Ma, Y, Vaidyanathan, G, Zalutsky, MR, Kirsch, DG, Badea, CT, and Vo-Dinh, T. "A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy." Theranostics 5, no. 9 (January 2015): 946-960. Full Text Open Access Copy
  - Pruszynski, M, Koumarianou, E, Vaidyanathan, G, Chitneni, S, and Zalutsky, MR. "D-Amino acid peptide residualizing agents bearing N-hydroxysuccinimido- and maleimido-functional groups and their application for trastuzumab radioiodination." Nuclear Medicine and Biology 42, no. 1 (January 2015): 19-27. Full Text Open Access Copy
  - Choi, J, Vaidyanathan, G, Koumarianou, E, McDougald, D, Pruszynski, M, Osada, T, Lahoutte, T, Lyerly, HK, and Zalutsky, MR. "N-Succinimidyl guanidinomethyl iodobenzoate protein radiohalogenation agents: influence of isomeric substitution on radiolabeling and target cell residualization." Nuclear medicine and biology 41, no. 10 (November 2014): 802-812. Full Text
  - Choi, J, Vaidyanathan, G, Koumarianou, E, McDougald, D, Pruszynski, M, Osada, T, Lahoutte, T, Lyerly, HK, and Zalutsky, MR. "N-Succinimidyl guanidinomethyl iodobenzoate protein radiohalogenation agents: Influence of isomeric substitution on radiolabeling and target cell residualization." Nuclear Medicine and Biology 41, no. 10 (November 1, 2014): 802-812. Full Text
  - Koumarianou, E, Slastnikova, TA, Pruszynski, M, Rosenkranz, AA, Vaidyanathan, G, Sobolev, AS, and Zalutsky, MR. "Radiolabeling and in vitro evaluation of (67)Ga-NOTA-modular nanotransporter--a potential Auger electron emitting EGFR-targeted radiotherapeutic." Nuclear medicine and biology 41, no. 6 (July 2014): 441-449. Full Text
  - Pruszynski, M, Koumarianou, E, Vaidyanathan, G, Revets, H, Devoogdt, N, Lahoutte, T, Lyerly, HK, and Zalutsky, MR. "Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabeling." Journal of nuclear medicine : official publication, Society of Nuclear Medicine 55, no. 4 (April 2014): 650-656. Full Text
  - Zhang, H, Huang, R, Pillarsetty, N, Thorek, DLJ, Vaidyanathan, G, Serganova, I, Blasberg, RG, and Lewis, JS. "Synthesis and evaluation of 18F-labeled benzylguanidine analogs for targeting the human norepinephrine transporter." Eur J Nucl Med Mol Imaging 41, no. 2 (February 2014): 322-332. Full Text Link to Item
  - Koumarianou, E, Slastnikova, TA, Pruszynski, M, Rosenkranz, AA, Vaidyanathan, G, Sobolev, AS, and Zalutsky, MR. "Radiolabeling and in vitro evaluation of ⁶⁷Ga-NOTA-modular nanotransporter - A potential Auger electron emitting EGFR-targeted radiotherapeutic." Nuclear Medicine and Biology 41, no. 6 (January 1, 2014): 441-449. Full Text
  - Zhang, H, Huang, R, Pillarsetty, NVK, Thorek, DLJ, Vaidyanathan, G, Serganova, I, Blasberg, RG, and Lewis, JS. "Synthesis and evaluation of ¹⁸F-labeled benzylguanidine analogs for targeting the human norepinephrine transporter." European Journal of Nuclear Medicine and Molecular Imaging 41, no. 2 (January 1, 2014): 322-332. Full Text
  - Barrott, JJ, Hughes, PF, Osada, T, Yang, X-Y, Hartman, ZC, Loiselle, DR, Spector, NL, Neckers, L, Rajaram, N, Hu, F, Ramanujam, N, Vaidyanathan, G, Zalutsky, MR, Lyerly, HK, and Haystead, TA. "Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells." Chem Biol 20, no. 9 (September 19, 2013): 1187-1197. Full Text Link to Item
  - Choi, J, Vaidyanathan, G, Koumarianou, E, Pruszynski, M, Lahoutte, T, and Zalutsky, MR. "Isomeric N-succinimidyl 3-guanidinomethyl-5-[I-131]iodobenzoate (iso-[I-131]SGMIB): A guanidine-containing residualizing agent for radiohalogenation of internalizing biomolecules." JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 56 (May 2013): S39-S39. Link to Item
  - Vaidyanathan, G, McDougald, D, Pruszynski, M, Koumarianou, E, Hens, MA, Lahoutte, T, and Zalutsky, MR. "SFBTMGMB (N-succinimidyl 3-((4-(4-fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate): An SGMIB analogue for labeling internalizing biomolecules with F-18." JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 56 (May 2013): S127-S127. Link to Item
  - Pruszynski, M, Koumarianou, E, Vaidyanathan, G, Revets, H, Devoogdt, N, Lahoutte, T, and Zalutsky, MR. "Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody." Nucl Med Biol 40, no. 1 (January 2013): 52-59. Full Text Link to Item
  - Pruszynski, M, Koumarianou, E, Vaidyanathan, G, Revets, H, Devoogdt, N, Lahoutte, T, and Zalutsky, MR. "Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody." Nuclear Medicine and Biology 40, no. 1 (2013): 52-59. Full Text
  - Weisenberger, AG, Bonito, G, Lee, S, McKisson, JE, Gryganskyi, A, Reid, CD, Smith, MF, Vaidyanathan, G, and Welch, B. "A radioisotope based methodology for plant-fungal interactions in the rhizosphere." Ieee Nuclear Science Symposium Conference Record (January 1, 2013). Full Text
  - Vaidyanathan, G, White, BJ, Affleck, DJ, Zhao, XG, Welsh, PC, McDougald, D, Choi, J, and Zalutsky, MR. "SIB-DOTA: a trifunctional prosthetic group potentially amenable for multi-modal labeling that enhances tumor uptake of internalizing monoclonal antibodies." Bioorganic & medicinal chemistry 20, no. 24 (December 2012): 6929-6939. Full Text
  - Chin, BB, Hjelemand, A, Rich, J, Song, H, Lascola, C, Storms, R, McLendon, R, Reiman, R, Greer, KL, Metzler, SD, McDougald, D, Dai, D, and Vaidyanathan, G. "Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression." Curr Radiopharm 5, no. 1 (January 2012): 47-58. Link to Item
  - Slastnikova, TA, Koumarianou, E, Rosenkranz, AA, Vaidyanathan, G, Lupanova, TN, Sobolev, AS, and Zalutsky, MR. "Modular nanotransporters: a versatile approach for enhancing nuclear delivery and cytotoxicity of Auger electron-emitting 125I." Ejnmmi Research 2, no. 1 (January 2012): 59-null. Full Text Open Access Copy
  - Vaidyanathan, G. "Virus hunters: catching bugs in the field." Cell 147, no. 6 (December 9, 2011): 1209-1211. Full Text Link to Item
  - Vaidyanathan, G. "Dam controversy: Remaking the Mekong. (Published online)" Nature 478, no. 7369 (October 19, 2011): 305-307. Full Text Link to Item
  - Vaidyanathan, G, McDougald, D, Grasfeder, L, Zalutsky, MR, and Chin, B. "An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine." Appl Radiat Isot 69, no. 10 (October 2011): 1401-1406. Full Text Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Applications of 211At and 223Ra in targeted alpha-particle radiotherapy." Curr Radiopharm 4, no. 4 (October 2011): 283-294. (Review) Link to Item
  - Vaidyanathan, G. "Apes in Africa: The cultured chimpanzees." Nature 476, no. 7360 (August 17, 2011): 266-269. Full Text
  - Vaidyanathan, G, Ngamphaiboon, N, and Hernandez-Ilizaliturri, FJ. "Clinical spectrum and prognosis of follicular lymphoma with blastoid transformation: case series and a review of the literature." Ann Hematol 90, no. 8 (August 2011): 955-962. (Review) Full Text Link to Item
  - Irikefe, V, Vaidyanathan, G, Nordling, L, Twahirwa, A, Nakkazi, E, and Monastersky, R. "Science in Africa: The view from the front line. (Published online)" Nature 474, no. 7353 (June 29, 2011): 556-559. Full Text Link to Item
  - Vaidyanathan, G. "Science in Africa: The wheat stalker. (Published online)" Nature 474, no. 7353 (June 29, 2011): 563-565. Full Text Link to Item
  - Vaidyanathan, G, McDougald, D, Affleck, DJ, and Zalutsky, MR. "A tin precursor of SGMIB potentially useful in the direct modification of peptides and proteins before radiohalogenation." JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 54 (2011): S64-S64. Link to Item
  - Vaidyanathan, G, White, B, Affleck, DJ, McDougald, D, and Zalutsky, MR. "Radioiodinated O(6)-Benzylguanine derivatives containing an azido function." Nuclear Medicine and Biology 38, no. 1 (January 2011): 77-92. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Applications of ²¹¹AT and ²²³RA in targeted alpha-particle radiotherapy." Current Radiopharmaceuticals 4, no. 4 (2011): 283-294.
  - Hens, M, Vaidyanathan, G, Zhao, X-G, Bigner, DD, and Zalutsky, MR. "Anti-EGFRvIII monoclonal antibody armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands." Nucl Med Biol 37, no. 7 (October 2010): 741-750. Full Text Link to Item
  - Kato, Y, Vaidyanathan, G, Kaneko, MK, Mishima, K, Srivastava, N, Chandramohan, V, Pegram, C, Keir, ST, Kuan, C-T, Bigner, DD, and Zalutsky, MR. "Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas." Nucl Med Biol 37, no. 7 (October 2010): 785-794. Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, Zhao, XG, Keir, ST, and Zalutsky, MR. "[¹⁷⁷Lu]-DOTA⁰-Tyr³-octreotate: A potential targeted radiotherapeutic for the treatment of Medulloblastoma." Current Radiopharmaceuticals 3, no. 1 (July 12, 2010): 29-36. Full Text
  - Vaidyanathan, G, and Fakih, MG. "A case of curative-intent hepatectomy for colon cancer metastatic to the scapula and liver." Anticancer Res 30, no. 2 (February 2010): 677-679. Link to Item
  - Vaidyanathan, G, Affleck, DJ, Zhao, X-G, Keir, ST, and Zalutsky, MR. "[Lu]-DOTA-Tyr-octreotate: A Potential Targeted Radiotherapeutic for the Treatment of Medulloblastoma." Curr Radiopharm 3, no. 1 (2010): 29-36. Full Text Link to Item
  - Vaidyanathan, G, Groman, A, Wilding, G, and Fakih, MG. "Stop and go FOLFOX plus bevacizumab chemotherapy in the first-line treatment of metastatic colorectal cancer." Oncology 79, no. 1-2 (2010): 67-71. Full Text Link to Item
  - Vaidyanathan, G, Song, H, Affleck, D, McDougald, DL, Storms, RW, Zalutsky, MR, and Chin, BB. "Targeting aldehyde dehydrogenase: a potential approach for cell labeling." Nucl Med Biol 36, no. 8 (November 2009): 919-929. Full Text Link to Item
  - Vaidyanathan, G, Jestin, E, Olafsen, T, Wu, AM, and Zalutsky, MR. "Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK." Nuclear Medicine and Biology 36, no. 6 (August 2009): 671-680. Full Text
  - Hens, M, Vaidyanathan, G, Welsh, P, and Zalutsky, MR. "Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: in vitro comparison of acyclic and macrocyclic ligands." Nuclear Medicine and Biology 36, no. 2 (February 2009): 117-128. Full Text
  - Vaidyanathan, G, White, B, Affleck, D, Zhao, X, Welsh, P, and Zalutsky, M. "DOTA-SIB, A TRIFUNCTIONAL PROSTHETIC GROUP FOR MULTI-MODAL LABELING." JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 52 (2009): S70-S70. Link to Item
  - Vaidyanathan, G, White, BJ, and Zalutsky, MR. "Propargyl 4-[F]fluorobenzoate: A Putatively More Stable Prosthetic group for the Fluorine-18 Labeling of Biomolecules via Click Chemistry." Current Radiopharmaceuticals 2, no. 1 (January 2009): 63-74. Full Text
  - Vaidyanathan, G. "Meta-iodobenzylguanidine and analogues: chemistry and biology." Q J Nucl Med Mol Imaging 52, no. 4 (December 2008): 351-368. (Review) Link to Item
  - Simmons, K, Kinney, J, Owens, A, Kleier, DA, Bloch, K, Argentar, D, Walsh, A, and Vaidyanathan, G. "Practical outcomes of applying ensemble machine learning classifiers to High-Throughput Screening (HTS) data analysis and screening." J Chem Inf Model 48, no. 11 (November 2008): 2196-2206. Full Text Link to Item
  - Rosenkranz, AA, Vaidyanathan, G, Pozzi, OR, Lunin, VG, Zalutsky, MR, and Sobolev, AS. "Engineered modular recombinant transporters: application of new platform for targeted radiotherapeutic agents to alpha-particle emitting 211 At." Int J Radiat Oncol Biol Phys 72, no. 1 (September 1, 2008): 193-200. Full Text Link to Item
  - Sun, C, Dobi, A, Mohamed, A, Li, H, Thangapazham, RL, Furusato, B, Shaheduzzaman, S, Tan, S-H, Vaidyanathan, G, Whitman, E, Hawksworth, DJ, Chen, Y, Nau, M, Patel, V, Vahey, M, Gutkind, JS, Sreenath, T, Petrovics, G, Sesterhenn, IA, McLeod, DG, and Srivastava, S. "TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation." Oncogene 27, no. 40 (September 2008): 5348-5353. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Astatine Radiopharmaceuticals: Prospects and Problems." Curr Radiopharm 1, no. 3 (September 1, 2008): 177-. Link to Item
  - Simmons, K, Kinney, J, Owens, A, Kleier, D, Bloch, K, Argentar, D, Walsh, A, and Vaidyanathan, G. "Comparative study of machine-learning and chemometric tools for analysis of in-vivo high-throughput screening data." J Chem Inf Model 48, no. 8 (August 2008): 1663-1668. Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, Norman, J, O'Dorisio, S, and Zalutsky, MR. "A radioiodinated MIBG-octreotate conjugate exhibiting enhanced uptake and retention in SSTR2-expressing tumor cells." Bioconjug Chem 18, no. 6 (November 2007): 2122-2130. Full Text Link to Item
  - Zalutsky, MR, Reardon, DA, Pozzi, OR, Vaidyanathan, G, and Bigner, DD. "Targeted alpha-particle radiotherapy with 211At-labeled monoclonal antibodies." Nucl Med Biol 34, no. 7 (October 2007): 779-785. (Review) Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, Alston, KL, Zhao, X-G, Hens, M, Hunter, DH, Babich, J, and Zalutsky, MR. "A kit method for the high level synthesis of [211At]MABG." Bioorganic & Medicinal Chemistry 15, no. 10 (May 2007): 3430-3436. Full Text
  - Park, J, Vaidyanathan, G, Singh, B, and Gupta, RS. "Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase." The Protein Journal 26, no. 3 (April 2007): 203-212. Full Text
  - Vaidyanathan, G, Affleck, DJ, Alston, KL, and Zalutsky, MR. "A tin precursor for the synthesis of no-carrier-added [*I]MIBG and [²¹¹At]MABG." Journal of Labelled Compounds and Radiopharmaceuticals 50, no. 3 (2007): 177-182. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides." Nat Protoc 2, no. 2 (2007): 282-286. Full Text Link to Item
  - Vaidyanathan, G, Alston, KL, Bigner, DD, and Zalutsky, MR. "Nepsilon-(3-[*I]Iodobenzoyl)-Lys5-Nalpha-maleimido-Gly1-GEEEK ([*I]IB-Mal-D-GEEEK): a radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies." Bioconjugate Chemistry 17, no. 4 (July 2006): 1085-1092. Full Text
  - Vaidyanathan, G, Alston, KL, Bigner, DD, and Zalutsky, MR. "N^ε-(3[*I]iodobenzoyl)-Lys⁵-N ^α-maleimido-Gly¹-GEEEK([*I]IB-Mal-D-GEEEK): A radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies." Bioconjugate Chemistry 17, no. 4 (July 1, 2006): 1085-1092. Full Text
  - Shankar, S, Zalutsky, MR, Friedman, H, and Vaidyanathan, G. "Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine." Nucl Med Biol 33, no. 3 (April 2006): 399-407. Full Text Link to Item
  - Shankar, S, Vaidyanathan, G, Kuan, C-T, Bigner, DD, and Zalutsky, MR. "Antiepidermal growth factor variant III scFv fragment: effect of radioiodination method on tumor targeting and normal tissue clearance." Nucl Med Biol 33, no. 1 (January 2006): 101-110. Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, Schottelius, M, Wester, H, Friedman, HS, and Zalutsky, MR. "Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor." Bioconjugate Chemistry 17, no. 1 (January 2006): 195-203. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Preparation of N-succinimidyl 3-[*I]iodobenzoate: an agent for the indirect radioiodination of proteins." Nature Protocols 1, no. 2 (January 2006): 707-713. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Synthesis of N-succinimidyl 4-[18F]fluorobenzoate, an agent for labeling proteins and peptides with 18F." Nat Protoc 1, no. 4 (2006): 1655-1661. Full Text Link to Item
  - Shankar, S, Zalutsky, MR, and Vaidyanathan, G. "O6-3-[125I]iodobenzyl-2'-deoxyguanosine ([125I]IBdG): synthesis and evaluation of its usefulness as an agent for quantification of alkylguanine-DNA alkyltransferase (AGT)." Bioorganic & Medicinal Chemistry 13, no. 12 (June 2005): 3889-3898. Full Text
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "No-carrier-added synthesis of a 4-methyl-substituted meta-iodobenzylguanidine analogue." Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine 62, no. 3 (March 2005): 435-440. Full Text
  - Vaidyanathan, G, Boskovitz, A, Shankar, S, and Zalutsky, MR. "Radioiodine and 211At-labeled guanidinomethyl halobenzoyl octreotate conjugates: potential peptide radiotherapeutics for somatostatin receptor-positive cancers." Peptides 25, no. 12 (December 2004): 2087-2097. Full Text
  - Shankar, S, Vaidyanathan, G, Affleck, DJ, Peixoto, K, Bigner, DD, and Zalutsky, MR. "Evaluation of an internalizing monoclonal antibody labeled using N-succinimidyl 3-[131I]iodo-4-phosphonomethylbenzoate ([131I]SIPMB), a negatively charged substituent bearing acylation agent." Nuclear Medicine and Biology 31, no. 7 (October 2004): 909-919. Full Text
  - Vaidyanathan, G, Welsh, PC, Vitorello, KC, Snyder, S, Friedman, HS, and Zalutsky, MR. "A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells." European Journal of Nuclear Medicine and Molecular Imaging 31, no. 10 (October 2004): 1362-1370. Full Text
  - Kumar, YR, Ramulu, G, Vevakanand, VV, Vaidyanathan, G, Srinivas, K, Kumar, MK, Mukkanti, K, Reddy, MS, Venkatraman, S, and Suryanarayana, MV. "A validated chiral HPLC method for the enantiomeric separation of tolterodine tartarate." J Pharm Biomed Anal 35, no. 5 (September 3, 2004): 1279-1285. Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, Alston, KL, Welsh, P, and Zalutsky, MR. "Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells." Nuclear Medicine Communications 25, no. 9 (September 2004): 947-955. Full Text
  - Boyd, M, Mairs, RJ, Keith, WN, Ross, SC, Welsh, P, Akabani, G, Owens, J, Vaidyanathan, G, Carruthers, R, Dorrens, J, and Zalutsky, MR. "An efficient targeted radiotherapy/gene therapy strategy utilising human telomerase promoters and radioastatine and harnessing radiation-mediated bystander effects." The Journal of Gene Medicine 6, no. 8 (August 2004): 937-947. Full Text
  - Vaidyanathan, G, Cismowski, MJ, Wang, G, Vincent, TS, Brown, KD, and Lanier, SM. "The Ras-related protein AGS1/RASD1 suppresses cell growth." Oncogene 23, no. 34 (July 29, 2004): 5858-5863. Full Text Link to Item
  - Vaidyanathan, G. "InfoEvolve: moving from data to knowledge using information theory and genetic algorithms." Ann N Y Acad Sci 1020 (May 2004): 227-238. Full Text Link to Item
  - Vaidyanathan, G, Shankar, S, Affleck, DJ, Alston, K, Norman, J, Welsh, P, LeGrand, H, and Zalutsky, MR. "Meta-iodobenzylguanidine derivatives containing a second guanidine moiety." Bioorganic & Medicinal Chemistry 12, no. 7 (April 2004): 1649-1656. Full Text
  - Vaidyanathan, G, Affleck, DJ, Norman, J, Welsh, P, Liu, W, Johnson, SP, Friedman, HS, and Zalutsky, MR. "O6-3-[131I]iodobenzylguanine: improved synthesis and further evaluation of a potential agent for imaging of alkylguanine-DNA alkyltransferase." Bioconjug Chem 15, no. 2 (March 2004): 402-408. Full Text Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Imaging drug resistance with radiolabeled molecules." Curr Pharm Des 10, no. 24 (2004): 2965-2979. (Review) Link to Item
  - Vaidyanathan, G. "Astatine-211 Labeled Radiopharmaceuticals, invited." Transactions of the American Nuclear Society 91 (2004): 856--.
  - Vivekanand, VV, Sreenivas Rao, D, Vaidyanathan, G, Sekhar, NM, Avijit Kelkar, S, and Ramachandra Puranik, P. "A validated LC method for imatinib mesylate." J Pharm Biomed Anal 33, no. 5 (December 4, 2003): 879-889. Link to Item
  - Vaidyanathan, G, Affleck, DJ, Bigner, DD, and Zalutsky, MR. "N-succinimidyl 3-[211At]astato-4-guanidinomethylbenzoate: an acylation agent for labeling internalizing antibodies with alpha-particle emitting 211At." Nuclear Medicine and Biology 30, no. 4 (May 2003): 351-359. Full Text
  - Vaidyanathan, G, Friedman, HS, Affleck, DJ, Schottelius, M, Wester, H-J, and Zalutsky, MR. "Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 9, no. 5 (May 2003): 1868-1876.
  - Shankar, S, Vaidyanathan, G, Affleck, D, Welsh, PC, and Zalutsky, MR. "N-succinimidyl 3-[(131)I]iodo-4-phosphonomethylbenzoate ([(131)I]SIPMB), a negatively charged substituent-bearing acylation agent for the radioiodination of peptides and mAbs." Bioconjugate Chemistry 14, no. 2 (March 2003): 331-341. Full Text
  - Shankar, S, Vaidyanathan, G, Affleck, DJ, Welsh, P, LeGrand, H, and Zalutsky, MR. "Negatively charged substituent-bearing acylation agent for the radiohalogenation of mAbs." JOURNAL OF NUCLEAR MEDICINE 43, no. 5 (May 2002): 366P-366P. Link to Item
  - Vaidyanathan, G, Affleck, DJ, Welsh, P, Schottelius, M, Wester, H, Norman, JA, Alston, KL, and Zalutsky, MR. "Synthesis and in vitro evaluation of glycated octreotate conjugates labeled with radioiodine and At-211 via a tin precursor." JOURNAL OF NUCLEAR MEDICINE 43, no. 5 (May 2002): 92P-92P. Link to Item
  - Dingus, J, Tatum, BS, Vaidyanathan, G, and Hilderbrandt, JD. "Purification of G protein beta gamma from bovine brain." Methods Enzymol 344 (2002): 194-208. Link to Item
  - Vaidyanathan, G, Affleck, DJ, Bigner, DD, and Zalutsky, MR. "Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate." Nuclear Medicine and Biology 29, no. 1 (January 2002): 1-11. Full Text
  - Vaidyanathan, G, Shankar, S, Affleck, DJ, Welsh, PC, Slade, SK, and Zalutsky, MR. "Biological evaluation of ring- and side-chain-substituted m-iodobenzylguanidine analogues." Bioconjug Chem 12, no. 5 (September 2001): 798-806. Link to Item
  - Vaidyanathan, G, Shankar, S, and Zalutsky, MR. "Synthesis of ring- and side-chain-substituted m-iodobenzylguanidine analogues." Bioconjugate Chemistry 12, no. 5 (September 2001): 786-797. Full Text
  - Vaidyanathan, G, Affleck, DJ, Li, J, Welsh, P, and Zalutsky, MR. "A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB)." Bioconjugate Chemistry 12, no. 3 (May 2001): 428-438. Full Text
  - Vaidyanathan, G, Affleck, DJ, Cavazos, CM, Johnson, SP, Shankar, S, Friedman, HS, Colvin, MO, and Zalutsky, MR. "Radiolabeled guanine derivatives for the in vivo mapping of O(6)-alkylguanine-DNA alkyltransferase: 6-(4-[(18)F]Fluoro-benzyloxy)-9H-purin-2-ylamine and 6-(3-[(131)I]Iodo-benzyloxy)-9H-purin-2-ylamine." Bioconjug Chem 11, no. 6 (November 2000): 868-875. Link to Item
  - Bardiès, M, and Pihet, P. "Dosimetry and microdosimetry of targeted radiotherapy." Current Pharmaceutical Design 6, no. 14 (September 2000): 1469-1502. (Review) Full Text
  - Zalutsky, MR, and Vaidyanathan, G. "Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy." Current Pharmaceutical Design 6, no. 14 (September 2000): 1433-1455. (Review) Full Text
  - Vaidyanathan, G, Affleck, D, Welsh, P, Srinivasan, A, Schmidt, M, and Zalutsky, MR. "Radioiodination and astatination of octreotide by conjugation labeling." Nucl Med Biol 27, no. 4 (May 2000): 329-337. Link to Item
  - Vaidyanathan, G, Affleck, D, Welsh, P, Srinivasan, A, Schmidt, M, and Zalutsky, MR. "Radioiodination and astatination of octreotide by conjugation labeling." Journal of Inorganic Biochemistry 78, no. 3 (February 29, 2000): 329-337.
  - Vaidyanathan, G, and Zalutsky, MR. "Low molecular weight radiopharmaceuticals: Radiohalogenated MIBG and IUdR analogues." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 217 (March 21, 1999): U41-U41. Link to Item
  - Vaidyanathan, G, Srinivasan, A, Affleck, DJ, Welsh, PC, Slade, SK, Schmidt, MA, and Zalutsky, MR. "Octreotide analogues labeled with radioiodine and astatine-211." Journal of Labelled Compounds and Radiopharmaceuticals 42, no. SUPPL. 1 (1999): S33-S35.
  - Vaidyanathan, G, Zalutsky, MR, and DeGrado, TR. "Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine." Bioconjugate Chemistry 9, no. 6 (November 1998): 758-764. Full Text
  - Wang, L, Kristensen, J, and Ruffner, DE. "Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules." Bioconjugate Chemistry 9, no. 6 (November 1998): 749-757. Full Text
  - Walicka, MA, Vaidyanathan, G, Zalutsky, MR, Adelstein, SJ, and Kassis, AI. "Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211." Radiat Res 150, no. 3 (September 1998): 263-268. Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Preparation of 5-[131I]iodo- and 5-[211At]astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil by a halodestannylation reaction." Nucl Med Biol 25, no. 5 (July 1998): 487-496. Link to Item
  - Cunningham, SH, Mairs, RJ, Wheldon, TE, Welsh, PC, Vaidyanathan, G, and Zalutsky, MR. "Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions." Br J Cancer 77, no. 12 (June 1998): 2061-2068. Open Access Copy Link to Item
  - Berry, CR, Vaidyanathan, G, Fisher, PE, Zalutsky, MR, Coleman, RE, and DeGrado, TR. "Myocardial kinetics of meta-[I-131]iodobenzylguanidine in an adriamycin cardiomyopathy rat model." JOURNAL OF NUCLEAR MEDICINE 39, no. 5 (May 1998): 47P-47P. Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Targeted therapy using astatinated radiopharmaceuticals." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 215 (April 2, 1998): U946-U946. Link to Item
  - DeGrado, TR, Zalutsky, MR, Coleman, RE, and Vaidyanathan, G. "Effects of specific activity on meta-[(131)I]iodobenzylguanidine kinetics in isolated rat heart." Nucl Med Biol 25, no. 1 (January 1998): 59-64. Link to Item
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "Method for radioiodination of proteins using N-succinimidyl 3-hydroxy-4-iodobenzoate." Bioconjug Chem 8, no. 5 (September 1997): 724-729. Full Text Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "A new route to guanidines from bromoalkanes." JOURNAL OF ORGANIC CHEMISTRY 62, no. 14 (July 11, 1997): 4867-4869. Full Text Link to Item
  - Larsen, RH, Vaidyanathan, G, and Zalutsky, MR. "Cytotoxicity of alpha-particle-emitting 5-[211At]astato-2'-deoxyuridine in human cancer cells." Int J Radiat Biol 72, no. 1 (July 1997): 79-90. Link to Item
  - Vaidyanathan, G, Zhao, XG, Larsen, RH, and Zalutsky, MR. "3-[At-211]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells." BRITISH JOURNAL OF CANCER 76, no. 2 (July 1997): 226-233. Full Text Link to Item
  - DeGrado, TR, Zalutsky, MR, and Vaidyanathan, G. "Mechanisms of uptake in isolated rat heart of potential radiotherapeutic agent [At-211]meta-astatobenzylguanidine (MABG)." JOURNAL OF NUCLEAR MEDICINE 38, no. 5 (May 1997): 106-106. Link to Item
  - Kassis, AI, Walicka, MA, Vaidyanathan, G, Zalutsky, MR, and Adelstein, SJ. "Survival and DNA damage in V79 cells exposed to the alpha emitters 5-[At-211]astato-2'-deoxy-uridine and [At-211]astatide." JOURNAL OF NUCLEAR MEDICINE 38, no. 5 (May 1997): 964-964. Link to Item
  - Vaidyanathan, G, Zhao, XG, Strickland, DK, and Zalutsky, MR. "No-carrier-added iodine-131-FIBG: evaluation of an MIBG analog." J Nucl Med 38, no. 2 (February 1997): 330-334. Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Fluorine-18-labeled [Nle4,D-Phe7]-alpha-MSH, an alpha-melanocyte stimulating hormone analogue." Nucl Med Biol 24, no. 2 (February 1997): 171-178. Link to Item
  - Vaidyanathan, G, Zhao, X-G, Larsen, RH, and Zalutsky, MR. "3-[²¹¹At]astato-4-fluorobenzylguanidine: A potential therapeutic agent with prolonged retention by neuroblastoma cells." British Journal of Cancer 76, no. 2 (1997): 226-233.
  - Vaidyanathan, G, Zhao, XG, Larsen, RH, and Zalutsky, MR. "3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells." British Journal of Cancer 76, no. 2 (January 1997): 226-233. Full Text Open Access Copy
  - Vaidyanathan, G, and Zalutsky, MR. "Fluorine-18-labeled [Nle⁴,D-Phe⁷]-α-MSH, an α-melanocyte stimulating hormone analogue." Nuclear Medicine and Biology 24, no. 2 (1997): 171-178. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Targeted therapy using alpha emitters." Physics in Medicine and Biology 41, no. 10 (October 1996): 1915-1931. (Review) Full Text
  - Vaidyanathan, G, Friedman, HS, Keir, ST, and Zalutsky, MR. "Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model." Nucl Med Biol 23, no. 6 (August 1996): 851-856. Link to Item
  - DeGrado, TR, Zalutsky, MR, Coleman, RE, and Vaidyanathan, G. "Effects of specific activity on uptake and retention of metaiodobenzylguanidine (MIBG) in the heart: Revisited." JOURNAL OF NUCLEAR MEDICINE 37, no. 5 (May 1996): 701-701. Link to Item
  - Vaidyanathan, G, Affleck, DJ, Welsh, PC, Slade, SA, Alston, KL, and Zalutsky, MR. "Fluorine-18 labeling of [Nle(4),D-Phe(7)]-alpha-MSH, an alpha-melanocyte stimulating hormone (alpha-MSH) analogue." JOURNAL OF NUCLEAR MEDICINE 37, no. 5 (May 1996): 875-875. Link to Item
  - Vaidyanathan, G, Friedman, HS, Keir, ST, and Zalutsky, MR. "Localisation of [131I]MIBG in nude mice bearing SK-N-SH human neuroblastoma xenografts: effect of specific activity." Br J Cancer 73, no. 10 (May 1996): 1171-1177. Open Access Copy Link to Item
  - Vaidyanathan, G, Friedman, HS, Keir, ST, and Zalutsky, MR. "Meta-[At-211]astatobenzylguanidine (MABG): In vivo evaluation in an athymic mouse human neuroblastoma xenograft model." JOURNAL OF NUCLEAR MEDICINE 37, no. 5 (May 1996): 236-236. Link to Item
  - Zweit, J, Flower, M, Brown, A, Carnochan, P, Luthra, S, Brady, F, Pike, V, Vaidyanathan, G, Zalutsky, M, Ott, R, and Jones, T. "Iodine-120-mIBG: Production and NCA labelling of a new PET radiotracer." JOURNAL OF NUCLEAR MEDICINE 37, no. 5 (May 1996): 874-874. Link to Item
  - Vaidyanathan, G, Larsen, RH, and Zalutsky, MR. "5-[211 At]astato-2'-deoxyuridine, an alpha particle-emitting endoradiotherapeutic agent undergoing DNA incorporation." Cancer Res 56, no. 6 (March 15, 1996): 1204-1209. Link to Item
  - Vaidyanathan, G, Larsen, RH, and Zalutsky, MR. "5-[At-211]astato-2'-deoxyuridine, an alpha-particle-emitting endoradiotherapeutic agent undergoing DNA incorporation." CANCER RESEARCH 56, no. 6 (March 15, 1996): 1204-1209. Link to Item
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "No-carrier-added (4-fluoro-3-[131I]iodobenzyl)guanidine and (3-[211At]astato-4-fluorobenzyl)guanidine." Bioconjug Chem 7, no. 1 (January 1996): 102-107. Full Text Link to Item
  - Vaidyanathan, G, Larsen, RH, and Zalutsky, MR. "Particle-emitting endoradiotherapeutic agent undergoing DNA incorporation." Cancer Research 56, no. 6 (1996): 1204-1209.
  - Reist, CJ, Archer, GE, Kurpad, SN, Wikstrand, CJ, Vaidyanathan, G, Willingham, MC, Moscatello, DK, Wong, AJ, Bigner, DD, and Zalutsky, MR. "Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts." Cancer Research 55, no. 19 (October 1995): 4375-4382.
  - Vaidyanathan, G, and Zalutsky, MR. "Fluorine-18 labeled chemotactic peptides: a potential approach for the PET imaging of bacterial infection." Nucl Med Biol 22, no. 6 (August 1995): 759-764. Link to Item
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "Validation of 4-[fluorine-18]fluoro-3-iodobenzylguanidine as a positron-emitting analog of MIBG." J Nucl Med 36, no. 4 (April 1995): 644-650. Link to Item
  - Degrado, TR, Zalutsky, MR, and Vaidyanathan, G. "Uptake mechanisms of meta-[123I]iodobenzylguanidine in isolated rat heart." Nucl Med Biol 22, no. 1 (January 1995): 1-12. Link to Item
  - Johnson, EL, Turkington, TG, Jaszczak, RJ, Gilland, DR, Vaidyanathan, G, Greer, KL, Coleman, RE, and Zalutsky, MR. "Quantitation of 211At in small volumes for evaluation of targeted radiotherapy in animal models." Nuclear Medicine and Biology 22, no. 1 (January 1995): 45-54. Full Text
  - Mairs, RJ, Russell, J, Cunningham, S, O'Donoghue, JA, Gaze, MN, Owens, J, Vaidyanathan, G, and Zalutsky, MR. "Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [131I]meta-iodobenzylguanidine: implications for the targeted radiotherapy of neuroblastoma." Eur J Cancer 31A, no. 4 (1995): 576-581. Link to Item
  - Mairs, RJ, Russell, J, Cunningham, S, O'Donoghue, JA, Gaze, MN, Owens, J, Vaidyanathan, G, and Zalutsky, MR. "Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [¹³¹i] metaiodobenzylguanidine: Implications for the targeted radiotherapy of neuroblastoma." European Journal of Cancer 31, no. 4 (1995): 576-581.
  - Strickland, DK, Vaidyanathan, G, Friedman, HS, and Zalutsky, MR. "Meta-[131I]iodobenzylguanidine uptake and meta-[211At]astatobenzylguanidine treatment in human medulloblastoma cell lines." Journal of Neuro Oncology 25, no. 1 (January 1995): 9-17. Full Text
  - Strickland, DK, Vaidyanathan, G, Friedman, HS, and Zalutsky, MR. "Meta-[¹³¹I]iodobenzylguanidine uptake and meta-[²¹¹At]astatobenzylguanidine treatment in human medulloblastoma cell lines." Journal of Neuro-Oncology 25, no. 1 (1995): 9-17. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "No-carrier-added meta-[123I]iodobenzylguanidine: synthesis and preliminary evaluation." Nucl Med Biol 22, no. 1 (January 1995): 61-64. Link to Item
  - VAIDYANATHAN, G, AFFLECK, DJ, and ZALUTSKY, MR. "(4-[F-18]FLUORO-3-IODOBENZYL) GUANIDINE, A POTENTIAL MIBG ANALOG FOR POSITRON EMISSION TOMOGRAPHY." JOURNAL OF MEDICINAL CHEMISTRY 37, no. 21 (October 14, 1994): 3655-3662. Full Text Link to Item
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "(4-[18F]fluoro-3-iodobenzyl)guanidine, a potential MIBG analogue for positron emission tomography." J Med Chem 37, no. 21 (October 14, 1994): 3655-3662. Link to Item
  - Page, RL, Garg, PK, Vaidyanathan, G, and Zalutsky, MR. "Preclinical evaluation and PET imaging of 18F-labeled Mel-14 F(ab')2 fragment in normal dogs." Nucl Med Biol 21, no. 7 (October 1994): 911-919. Link to Item
  - Strickland, DK, Vaidyanathan, G, and Zalutsky, MR. "Cytotoxicity of alpha-particle-emitting m-[211At]astatobenzylguanidine on human neuroblastoma cells." Cancer Research 54, no. 20 (October 1994): 5414-5419.
  - Vaidyanathan, G, and Zalutsky, MR. "Improved synthesis of N-succinimidyl 4-[18F]fluorobenzoate and its application to the labeling of a monoclonal antibody fragment." Bioconjug Chem 5, no. 4 (July 1994): 352-356. Link to Item
  - Vaidyanathan, G, Strickland, DK, and Zalutsky, MR. "Meta-[211At]astatobenzylguanidine: further evaluation of a potential therapeutic agent." International Journal of Cancer 57, no. 6 (June 1994): 908-913. Full Text
  - DEGRADO, TR, ZALUTSKY, MR, AFFLECK, DJ, and VAIDYANATHAN, G. "MECHANISTIC STUDIES OF METAIODOBENZYLGUANIDINE (METAIODOBENZYLGUANIDINE) UPTAKE AND RETENTION IN ISOLATED RAT-HEART." JOURNAL OF NUCLEAR MEDICINE 35, no. 5 (May 1994): P57-P57. Link to Item
  - JOHNSON, EL, TURKINGTON, TG, JASZCZAK, RJ, ZALUTSKY, MR, GILLAND, DR, VAIDYANATHAN, G, GREER, KL, and COLEMAN, RE. "QUANTITATIVE IMAGING OF AT-211 RADIOTHERAPEUTIC AGENTS IN SMALL VOLUMES." JOURNAL OF NUCLEAR MEDICINE 35, no. 5 (May 1994): P180-P180. Link to Item
  - VAIDYANATHAN, G, AFFLECK, DJ, SLADE, SA, WELSH, PC, and ZALUTSKY, MR. "SYNTHESIS AND PRELIMINARY EVALUATION OF 4-[F-18]FLUORO-3-IODOBENZYLGUANIDINE (FIBG) - A METAIODOBENZYLGUANIDINE ANALOG FOR PET." JOURNAL OF NUCLEAR MEDICINE 35, no. 5 (May 1994): P248-P248. Link to Item
  - Mairs, RJ, Gaze, MN, Watson, DG, Skellern, GG, Constable, P, McKellar, K, Owens, J, Vaidyanathan, G, and Zalutsky, MR. "Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine." Nucl Med Commun 15, no. 4 (April 1994): 268-274. Link to Item
  - Shepherd, NS, Pfrogner, BD, Coulby, JN, Ackerman, SL, Vaidyanathan, G, Sauer, RH, Balkenhol, TC, and Sternberg, N. "Preparation and screening of an arrayed human genomic library generated with the P1 cloning system." Proceedings of the National Academy of Sciences of the United States of America 91, no. 7 (March 1994): 2629-2633. Full Text
  - Gaze, MN, Mairs, RJ, Vaidyanathan, G, and Zalutsky, MR. "Synthesis of carrier-free 131I-meta-iodobenzyl-guanidine by novel routes to enhance therapeutic efficiency in neuroblastoma." Prog Clin Biol Res 385 (1994): 347-353. Link to Item
  - Vaidyanathan, G, Affleck, D, and Zalutsky, MR. "Monoclonal antibody F(ab')2 fragment labeled with N-succinimidyl 2,4-dimethoxy-3-halobenzoates: in vivo comparison of iodinated and astatinated fragments." Nuclear Medicine and Biology 21, no. 1 (January 1994): 105-110. Full Text
  - Vaidyanathan, G, Affleck, DA, Welsh, P, and Zalutsky, MR. "Fluorine-18 labeled chemotactic peptide: A potential agent for the PET imaging of focal infection." Journal of Labelled Compounds and Radiopharmaceuticals 35 (1994): 365-367.
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "(4-[¹⁸F]fluoro-3-iodobenzyl)guanidine, a potential mibg analogue for positron emission tomography." Journal of Medicinal Chemistry 37, no. 21 (1994): 3655-3662.
  - Vaidyanathan, G, Strickland, DK, Affleck, DA, Welsh, P, and Zalutsky, MR. "Meta-[²¹¹At]astatobenzylguanidine: Further validation of in vitro and in vivo uptake mechanisms." Journal of Labelled Compounds and Radiopharmaceuticals 35 (1994): 589-591.
  - Vaidyanathan, G, Strickland, DK, and Zalutsky, MR. "Meta-[²¹¹At]astatobenzylguanidine: Further evaluation of a potential therapeutic agent." International Journal of Cancer 57, no. 6 (1994): 908-913. Full Text
  - DEGRADO, TR, ZALUTSKY, MR, AFFLECK, DJ, and VAIDYANATHAN, G. "UPTAKE MECHANISMS OF I-123 METAIODOBENZYLGUANIDINE (METAIODOBENZYLGUANIDINE) IN ISOLATED RAT-HEART." CIRCULATION 88, no. 4 (October 1993): 355-355. Link to Item
  - Turkington, TG, Zalutsky, MR, Jaszczak, RJ, Garg, PK, Vaidyanathan, G, and Coleman, RE. "Measuring astatine-211 distributions with SPECT." Physics in Medicine and Biology 38, no. 8 (August 1993): 1121-1130. Full Text
  - TURKINGTON, TG, ZALUTSKY, MR, JASZCZAK, RJ, GARG, P, VAIDYANATHAN, G, and COLEMAN, RE. "MEASURING ASTATINE-211 DISTRIBUTIONS WITH SPECT." JOURNAL OF NUCLEAR MEDICINE 34, no. 5 (May 1993): P191-P191. Link to Item
  - VAIDYANATHAN, G, HARRISON, C, WELSH, P, AFFLECK, D, and ZALUTSKY, MR. "INVITRO CYTOTOXICITY OF M-[AT-211]ASTATOBENZYLGUANIDINE (MABG)." JOURNAL OF NUCLEAR MEDICINE 34, no. 5 (May 1993): P218-P218. Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "No-carrier-added synthesis of meta-[131I]iodobenzylguanidine." Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine 44, no. 3 (March 1993): 621-628. Full Text
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "Radioiodination of proteins using N-succinimidyl 4-hydroxy-3-iodobenzoate." Bioconjugate Chemistry 4, no. 1 (January 1993): 78-84. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "1-(m-[211At]astatobenzyl)guanidine: synthesis via astato demetalation and preliminary in vitro and in vivo evaluation." Bioconjugate Chemistry 3, no. 6 (November 1992): 499-503. Full Text
  - Vaidyanathan, G, Bigner, DD, and Zalutsky, MR. "Fluorine-18-labeled monoclonal antibody fragments: a potential approach for combining radioimmunoscintigraphy and positron emission tomography." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 33, no. 8 (August 1992): 1535-1541.
  - Vaidyanathan, G, and Zalutsky, MR. "Labeling proteins with fluorine-18 using N-succinimidyl 4-[18F]fluorobenzoate." International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology 19, no. 3 (April 1992): 275-281. Full Text
  - VAIDYANATHAN, G, and ZALUTSKY, MR. "1-(M-[AT-211]ASTATOBENZYL)GUANIDINE - SYNTHESIS VIA ASTATO DEMETALATION AND PRELIMINARY INVITRO AND INVIVO EVALUATION." BIOCONJUGATE CHEMISTRY 3, no. 6 (1992): 499-503. Full Text Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "1-(m-[²¹¹At]astatobenzyl)guanidine: Synthesis via astato demetalation and preliminary in vitro and in vivo evaluation." Bioconjugate Chemistry 3, no. 6 (1992): 499-503.
  - Vaidyanathan, G, and Zalutsky, MR. "Labeling proteins with fluorine-18 using N-succinimidyl 4-[¹⁸F]fluorobenzoate." Nuclear Medicine and Biology 19, no. 3 (1992): 275-281. Full Text
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "Aromatic acylation reagents for use in the radioiodination of proteins." Journal of Labelled Compounds and Radiopharmaceuticals 30 (1991): 209-210.
  - Vaidyanathan, G, Jay, M, Bera, RK, Mayer, PR, and Brazzell, RK. "Scintigraphic evaluation of the ocular disposition of 18F-imirestat in rabbits." Pharm Res 7, no. 11 (November 1990): 1198-1200. Link to Item
  - Vaidyanathan, G, and Zalutsky, MR. "Radioiodination of antibodies via N-succinimidyl 2,4-dimethoxy-3-(trialkylstannyl)benzoates." Bioconjugate Chemistry 1, no. 6 (November 1990): 387-393. Full Text
  - Vaidyanathan, G, and Zalutsky, MR. "Protein radiohalogenation: observations on the design of N-succinimidyl ester acylation agents." Bioconjug Chem 1, no. 4 (July 1990): 269-273. Link to Item
  - GARG, PK, VAIDYANATHAN, G, GARG, S, and ZALUTSKY, MR. "RADIOIODINATION AND ASTATINATION OF MONOCLONAL-ANTIBODIES." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 199 (April 22, 1990): 16-NUCL. Link to Item
  - Vaidyanathan, G, and Wilson, JW. "Reaction of cyclopropanamines with hypochlorite." Journal of Organic Chemistry 54, no. 8 (1989): 1815-1820.
  - Vaidyanathan, G, and Wilson, JW. "Decarboxylation of 1-aminocyclopropanecarboxylic acid and its derivatives." Journal of Organic Chemistry 54, no. 8 (1989): 1810-1815.
- Conference Papers
  - Chin, B, Hawk, T, Weitzel, D, McDougald, D, Reiman, R, Palmer, G, Zalutsky, M, and Vaidyanathan, G. "Feasibility of 124I anti-PD-L1 PET/CT imaging in a syngeneic tumor model of breast cancer." May 1, 2017. Link to Item
  - Zhou, Z, Devoogdt, N, Zalutsky, M, and Vaidyanathan, G. "Labeling an anti-HER2 VHH with F-18 using a residualizing prosthetic group via strain-promoted click reaction: preliminary evaluation." May 1, 2017. Link to Item
  - Vaidyanathan, GV, Zhou, Z, McDougald, D, Lahoutte, T, and Zalutsky, MR. "Anti-HER2 Single Domain Antibody 2Rs15d Labeled with F-18 Using a Residualizing Label: Preliminary Evaluation." October 2016. Link to Item
  - Kiess, A, Minn, I, Vaidyanathan, G, Hobbs, R, Josefsson, A, Shen, C, Brummet, M, Chen, Y, Choi, J, Koumarianou, E, Baidoo, K, Brechbiel, M, Mease, R, Sgouros, G, Zalutsky, M, and Pomper, M. "[211At]YC-I-27 for PSMA-Targeted Alpha-Particle Radiopharmaceutical Therapy." : SOC NUCLEAR MEDICINE INC, May 1, 2016. Link to Item
  - Mease, R, Vaidyanathan, G, McGougald, D, Choi, J, Chen, Y, Shallal, H, Brummet, M, Shen, C, Minn, IL, Kiess, A, Sgouros, G, Zalutsky, M, and Pomper, M. "211At-Labeled Small-Molecule PSMA Inhibitors: Effect of Structure on Biodistribution in Mice." : SOC NUCLEAR MEDICINE INC, May 1, 2016. Link to Item
  - Vaidyanathan, G, McDougald, D, Choi, J, Koumarianou, E, Pruszynski, M, Osada, T, Lyerly, H, Lahoutte, T, and Zalutsky, MR. "An Anti-HER2 Nanobody Labeled with 18F Using a Residualizing Label for Assessing HER2 Status." October 2015. Link to Item
  - Batra, V, Ranieri, P, Makvandi, M, Tsang, M, Hou, C, Li, Y, Vaidyanathan, G, Pryma, DA, and Maris, JM. "Abstract 1610: Development of meta-[211At]astatobenzylguanidine ([211At]MABG) as an alpha particle emitting systemic targeted radiotherapeutic for neuroblastoma." August 1, 2015. Full Text
  - Batra, V, Makvandi, M, Ranieri, P, Tsang, M, Hou, C, Li, Y, Vaidyanathan, G, Maris, J, and Pryma, D. "Preclinical development of Meta-[At-211]astatobenzylguanidine ([At-211]MABG) as an alpha particle emitting systemic targeted radiotherapeutic for neuroblastoma (NB)." May 1, 2015. Link to Item
  - Choi, J, Vaidyanathan, G, Koumarianou, E, Lahoutte, T, and Zalutsky, M. "A At-211-labeled nanobody for alpha-particle therapy of HER2-expressing cancers." May 1, 2015. Link to Item
  - Vaidyanathan, G, Gururangan, S, Bigner, D, and Zalutsky, M. "PRE-CLINICAL EFFICACY STUDY OF INTRA-THECAL (IT) (LU)-L-177-DOTA-TATE (SOMATOSTATIN ANALOGUE) IN ATHYMIC RATS WITH LEPTOMENINGEAL DISEASE (LMD) FROM MEDULLOBLASTOMA (MBL)." June 2014. Link to Item
  - Slastnikova, T, Koumarianou, E, Rosenkranz, A, Vaidyanathan, G, Zalutsky, M, and Sobolev, A. "Modular nanotransporters efficiently deliver Auger electron emitters into nuclei of cancer cells." July 2013. Link to Item
  - Chin, B, Grasfeder, L, McDougald, D, and Vaidyanathan, G. "Iodoquine as a potential PET radiolabel for in vivo cell trafficking of leukocyte tumor cell lines." : SOC NUCLEAR MEDICINE INC, May 1, 2012. Link to Item
  - Koumarianou, E, Slastnikova, T, Pruszynski, M, Zhao, X-G, Rosenkranz, A, Vaidyanathan, G, Sobolev, A, and Zalutsky, M. "Modular nanotransporters: A flexible platform forward for targeted Auger electron therapy." : SOC NUCLEAR MEDICINE INC, May 1, 2012. Link to Item
  - Zalutsky, MR, and Vaidyanathan, G. "TARGETED ALPHA THERAPY." : ELSEVIER IRELAND LTD, March 1, 2012. Link to Item
  - Vaidyanathan, G, Li, J, Bigner, DD, and Zalutsky, MR. "TARGETED RADIOTHERAPY OF MEDULLOBLASTOMA USING SOMATOSTATIN RECEPTOR AVID RADIOLABELED PEPTIDES." May 2011. Link to Item
  - Vaidyanathan, G, MacDougald, D, Grasfeder, L, Zalutsky, M, and Chin, B. "An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine." : SOC NUCLEAR MEDICINE INC, May 1, 2011. Link to Item
  - Vaidyanathan, G, White, B, Affleck, DJ, McDougald, D, and Zalutsky, MR. "Radioiodinated O6-Benzylguanine Analogues Containing an Azido Function." October 2010. Link to Item
  - Chin, B, Reiman, R, Song, H, and Vaidyanathan, G. "Radiation dose estimates of [123I] and [131I] iodoquine, putative radiotracers targeting cells with high ALDH expression." : SOC NUCLEAR MEDICINE INC, May 1, 2009. Link to Item
  - Vaidyanathan, G, Mease, R, Affleck, D, Chen, Y, Welsh, P, Hens, M, Pomper, M, and Zalutsky, M. "An astatine-211 labeled PSMA inhibitor for targeted alpha-particle radiotherapy of prostate carcinoma." : SOC NUCLEAR MEDICINE INC, May 1, 2009. Link to Item
  - Barrett, JA, Coleman, R, Morse, M, Borys, N, Kronauge, J, Stubbs, JB, Mok, H, Qi, F, Petry, NN, Petry, NN, Vaidyanathan, G, and Babich, JW. "Phase 1 study of radiation dosimetry and clearance of no carrier added 131I-MIBG (ultratrace iobenguane) in 7 carcinoid and 4 pheochromocytoma patients." October 2007. Link to Item
  - Chin, BB, Storms, RW, Base, K, Lascola, C, Haystead, T, Zalutsky, MR, and Vaidyanathan, G. "[I-125] iodoquine uptake in tumor cell lines with high ALDH expression." October 2007. Link to Item
  - Zalutsky, MR, Reardon, DA, Pozzi, OR, Vaidyanathan, G, and Bigner, DD. "Targeted α-particle radiotherapy with 211At-labeled monoclonal antibodies." October 2007. Full Text
  - Vaidyanathan, G, Alston, KL, Welsh, PC, and Zalutsky, MR. "Enhanced cellular retention of an internalizing anti-EGFRvIII monoclonal antibody radioiodinated using LYS5-[*I]iodobenzoyl Gly(1)-maleimido GEEEK ([*I]IB-Mal-D-GEEEK), a prosthetic group containing negatively charged D-glutamates." July 2005. Link to Item
  - Vaidyanathan, G, Base, K, and Zalutsky, MR. "0(6)-{4-(3-[F-18]fluoropropyl)-benzyl}-2 '-deoxyguanosine ([F-18]FPBdG) - Synthesis and evaluation of a potential DNA repair protein 0(6)-alkyguanine-DNA alkyltransferase (AGT) imaging agent." March 13, 2005. Link to Item
  - Boskovitz, A, Vaidyanathan, G, Archer, GE, Ochiai, H, Okamura, T, Sampson, JH, Bigner, DD, and Zalutsky, MR. "Medulloblastoma neoplastic meningitis targeted radiotherapy with intrathecal alpha-emitter At-211-labeled thymidine analogue." October 2004. Link to Item
  - Vaidyanathan, G, Boskovitz, A, Friedman, HS, Affleck, DJ, and Zalutsky, MR. "Somatostatin targeted radiotherapeuiccs for medulloblastoma." October 2004. Link to Item
  - Vaidyanathan, G, Affleck, DJ, and Zalutsky, MR. "N-succinimidyl 3-[211AT]astato-4-guanidinomethylbenzoate: An acylation agent for labeling internalizing antibodies with alpha-particle emitting (211)AT." March 2003. Link to Item
  - VAIDYANATHAN, G, AFFLECK, DJ, SLADE, SA, WELSH, P, and ZALUTSKY, MR. "NO-CARRIER-ADDED 4-FLUORO-3-IODOBENZYLGUANIDINE LABELED WITH I-131 ([I-131]FIBG) AND F-18 ([F-18]FIBG - POTENTIAL MIBG ANALOGS FOR PET IMAGING AND THERAPY OF NEUROENDOCRINE TUMORS." 1994. Link to Item
  - Vaidyanathan, G, Strickland, DK, Affleck, DA, Welsh, P, and Zalutsky, MR. "Meta-[²¹¹At]astatobenzylguanidine: Further validation of in vitro and in vivo uptake mechanisms." January 1, 1994.
Teaching & Mentoring
Recent Courses
- MEDPHY 746: Radiopharmaceutical Chemistry 2017

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