Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral, College Of Pharmacy, University of Kentucky at Lexington 1987 - 1989
  • Teaching Assistant, Chemistry Dept, University of Kentucky at Lexington 1983 - 1987
  • Ph.D., University of Kentucky at Lexington 1987
• 

  Duke Appointment History

  • Professor in Radiology, Radiology, Clinical Science Departments 2006 - 2018
  • Research Professor in Radiology, Radiology, Clinical Science Departments 2005 - 2006
  • Associate Research Professor in Radiology, Radiology, Clinical Science Departments 1998 - 2005
  • Assistant Research Professor in Radiology, Radiology, Clinical Science Departments 1994 - 1998
• Research
• 

  Selected Grants

  • Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1985 - 2020
  • Labeling nanobodies with 18F residualizing labels for HER2 specific PET imaging awarded by National Institutes of Health 2015 - 2020
  • Cereius research agreement 2017 - 2019
  • Development of Tethered Hsp90 Inhibitors Carrying Radioiodinated Probes to Specifically Discriminate and Kill Malignant awarded by Department of Defense 2015 - 2019
  • Small Molecule PSMA-Targeted Alpha Therapy awarded by Johns Hopkins University 2014 - 2019
  • Novel Radiohalogenation Strategies for Enhancing Imaging and Targeted Radiotherapy awarded by Memorial Sloan Kettering Cancer Center 2016 - 2018
  • Development of a Targeted Radionuclide Therapy for Triple Negative Breast Cancer 2016 - 2017
  • Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
  • Enhancing the efficacy of targeted radiotherapy for neuroblastoma awarded by Children's Hospital of Philadelphia 2013 - 2014
  • Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
  • Brain Tumors - Immunological and Biological Studies awarded by National Institutes of Health 2001 - 2013
  • Small Animal PET / CT Molecular Imaging awarded by National Institutes of Health 2011 - 2012
  • Radionuclide-based Molecular Imaging of the DNA Repair Protein AGT awarded by National Institutes of Health 2009 - 2011
  • Astatine-211 Radiochemistry: The Development of Methodologies for High Activity Level Radio-Synthesis awarded by Department of Energy 2008 - 2010
  • Research Training In Neuro-Oncology awarded by National Institutes of Health 2005 - 2010
  • Imaging of O6-Alkylguianine-DNA Alkyltransferase awarded by National Institutes of Health 2002 - 2007
  • Targeted Radiotherapeutics: Chemical and Biological Aspects awarded by Department of Energy 2004 - 2006
  • Astatine-211 & Radioiodine Labeled Octreotide Conjugates awarded by National Institutes of Health 2001 - 2006
  • Anti-Tenascin Antibody Constructs awarded by Department of Energy 1995 - 2005
  • Molecular Imaging Center Planning Grant awarded by National Institutes of Health 2000 - 2004
  • Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1999 - 2004
  • MIBG Analogue Radiopharmaceuticals awarded by National Institutes of Health 1997 - 2003
  • Brain Tumors--Immunological and Biological Studies awarded by National Institutes of Health 1976 - 2001
  • Brain Tumors - Immunological And Biological Studies awarded by National Institutes of Health 1997 - 1999
  • Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
  • Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1994 - 1999
  • Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1993 - 1999
  • Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1985 - 1999
  • Positron Emission Imaging Of Tumors Using Monoclonal Antib awarded by Department of Energy 1995 - 1998
  • Migb And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1994 - 1998
  • Mibg And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
  • Mibg And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
  • Migb And Analogs For Diagnosis And Therapy awarded by National Institutes of Health 1993 - 1998
  • Cancer And Leukemia Group B Statistical Center awarded by National Institutes of Health 1992 - 1993
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Liu, Yang, Austin B. Carpenter, Christopher J. Pirozzi, Hsiangkuo Yuan, Matthew S. Waitkus, Zhengyuan Zhou, Landon Hansen, et al. “Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe..” Nanotechnology 30, no. 27 (March 11, 2019). https://doi.org/10.1088/1361-6528/ab0e9c.
       Full Text  Link to Item
    • Zhou, Zhengyuan, Darryl McDougald, Nick Devoogdt, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios..” Mol Pharm 16, no. 1 (January 7, 2019): 214–26. https://doi.org/10.1021/acs.molpharmaceut.8b00951.
       Full Text  Link to Item
    • Zhou, Zhengyuan, Nick Devoogdt, Michael R. Zalutsky, and Ganesan Vaidyanathan. “An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker..” Bioconjug Chem 29, no. 12 (December 19, 2018): 4090–4103. https://doi.org/10.1021/acs.bioconjchem.8b00699.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Choong Mo Kang, Darryl McDougald, Il Minn, Mary Brummet, Martin G. Pomper, and Michael R. Zalutsky. “Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors..” Nucl Med Biol 62–63 (July 2018): 18–30. https://doi.org/10.1016/j.nucmedbio.2018.05.002.
       Full Text  Link to Item
    • Pruszynski, Marek, Choong Mo Kang, Eftychia Koumarianou, Ganesan Vaidyanathan, and Michael R. Zalutsky. “d-Amino Acid Peptide Residualizing Agents for Protein Radioiodination: Effect of Aspartate for Glutamate Substitution..” Molecules 23, no. 5 (May 20, 2018). https://doi.org/10.3390/molecules23051223.
       Full Text  Link to Item
    • Zhou, Zhengyuan, Satish K. Chitneni, Nick Devoogdt, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation..” Bioorg Med Chem 26, no. 8 (May 1, 2018): 1939–49. https://doi.org/10.1016/j.bmc.2018.02.040.
       Full Text  Link to Item
    • Choi, Jaeyeon, Ganesan Vaidyanathan, Eftychia Koumarianou, Choong Mo Kang, and Michael R. Zalutsky. “Astatine-211 labeled anti-HER2 5F7 single domain antibody fragment conjugates: radiolabeling and preliminary evaluation..” Nucl Med Biol 56 (January 2018): 10–20. https://doi.org/10.1016/j.nucmedbio.2017.09.003.
       Full Text  Open Access Copy  Link to Item
    • Zhou, Zhengyuan, Ganesan Vaidyanathan, Darryl McDougald, Choong Mo Kang, Irina Balyasnikova, Nick Devoogdt, Angeline N. Ta, Brian R. McNaughton, and Michael R. Zalutsky. “Fluorine-18 Labeling of the HER2-Targeting Single-Domain Antibody 2Rs15d Using a Residualizing Label and Preclinical Evaluation..” Mol Imaging Biol 19, no. 6 (December 2017): 867–77. https://doi.org/10.1007/s11307-017-1082-x.
       Full Text  Link to Item
    • Chin, Bennett B., Darryl McDougald, Douglas H. Weitzel, Thomas Hawk, Robert E. Reiman, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine..” Curr Radiopharm 10, no. 1 (2017): 41–50. https://doi.org/10.2174/1874471009666161230114954.
       Full Text  Open Access Copy  Link to Item
    • Kiess, Ana P., Il Minn, Ganesan Vaidyanathan, Robert F. Hobbs, Anders Josefsson, Colette Shen, Mary Brummet, et al. “(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy..” J Nucl Med 57, no. 10 (October 2016): 1569–75. https://doi.org/10.2967/jnumed.116.174300.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Jaeyeon Choi, Eftychia Koumarianou, Douglas Weitzel, Takuya Osada, H Kim Lyerly, and Michael R. Zalutsky. “Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET..” J Nucl Med 57, no. 6 (June 2016): 967–73. https://doi.org/10.2967/jnumed.115.171306.
       Full Text  Link to Item
    • Chin, Bennett, Darryl McDougald, Douglas Weitzel, Thomas Hawk, Robert Reiman, Michael Zalutsky, and Ganesan Vaidyanathan. “Synthesis and preliminary evaluation of 5-[18F]fluoroleucine: a novel LAT1 substrate.” Journal of Nuclear Medicine 57 (May 1, 2016).
       Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Jaeyeon Choi, Marek Pruszynski, Eftychia Koumarianou, Zhengyuan Zhou, and Michael R. Zalutsky. “N-Succinimidyl 3-((4-(4-[(18)F]fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate ([(18)F]SFBTMGMB): a residualizing label for (18)F-labeling of internalizing biomolecules..” Org Biomol Chem 14, no. 4 (January 28, 2016): 1261–71. https://doi.org/10.1039/c5ob02258d.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Eftychia Koumarianou, Jaeyeon Choi, Marc Hens, and Michael R. Zalutsky. “Synthesis and evaluation of 4-[18F]fluoropropoxy-3-iodobenzylguanidine ([18F]FPOIBG): A novel 18F-labeled analogue of MIBG..” Nucl Med Biol 42, no. 8 (August 2015): 673–84. https://doi.org/10.1016/j.nucmedbio.2015.04.005.
       Full Text  Link to Item
    • Liu, Yang, Jeffrey R. Ashton, Everett J. Moding, Hsiangkuo Yuan, Janna K. Register, Andrew M. Fales, Jaeyeon Choi, et al. “A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy..” Theranostics 5, no. 9 (2015): 946–60. https://doi.org/10.7150/thno.11974.
       Full Text  Open Access Copy  Link to Item
    • Pruszynski, Marek, Eftychia Koumarianou, Ganesan Vaidyanathan, Satish Chitneni, and Michael R. Zalutsky. “D-Amino acid peptide residualizing agents bearing N-hydroxysuccinimido- and maleimido-functional groups and their application for trastuzumab radioiodination..” Nucl Med Biol 42, no. 1 (January 2015): 19–27. https://doi.org/10.1016/j.nucmedbio.2014.08.007.
       Full Text  Open Access Copy  Link to Item
    • Choi, Jaeyeon, Ganesan Vaidyanathan, Eftychia Koumarianou, Darryl McDougald, Marek Pruszynski, Takuya Osada, Tony Lahoutte, H Kim Lyerly, and Michael R. Zalutsky. “N-Succinimidyl guanidinomethyl iodobenzoate protein radiohalogenation agents: influence of isomeric substitution on radiolabeling and target cell residualization..” Nucl Med Biol 41, no. 10 (November 2014): 802–12. https://doi.org/10.1016/j.nucmedbio.2014.07.005.
       Full Text  Link to Item
    • Koumarianou, Eftychia, Tatiana A. Slastnikova, Marek Pruszynski, Andrey A. Rosenkranz, Ganesan Vaidyanathan, Alexander S. Sobolev, and Michael R. Zalutsky. “Radiolabeling and in vitro evaluation of (67)Ga-NOTA-modular nanotransporter--a potential Auger electron emitting EGFR-targeted radiotherapeutic..” Nucl Med Biol 41, no. 6 (July 2014): 441–49. https://doi.org/10.1016/j.nucmedbio.2014.03.026.
       Full Text  Link to Item
    • Pruszynski, Marek, Eftychia Koumarianou, Ganesan Vaidyanathan, Hilde Revets, Nick Devoogdt, Tony Lahoutte, H Kim Lyerly, and Michael R. Zalutsky. “Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabeling..” J Nucl Med 55, no. 4 (April 2014): 650–56. https://doi.org/10.2967/jnumed.113.127100.
       Full Text  Link to Item
    • Zhang, Hanwen, Ruimin Huang, NagaVaraKishore Pillarsetty, Daniel L. J. Thorek, Ganesan Vaidyanathan, Inna Serganova, Ronald G. Blasberg, and Jason S. Lewis. “Synthesis and evaluation of 18F-labeled benzylguanidine analogs for targeting the human norepinephrine transporter..” Eur J Nucl Med Mol Imaging 41, no. 2 (February 2014): 322–32. https://doi.org/10.1007/s00259-013-2558-9.
       Full Text  Link to Item
    • Barrott, Jared J., Philip F. Hughes, Takuya Osada, Xiao-Yi Yang, Zachary C. Hartman, David R. Loiselle, Neil L. Spector, et al. “Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells..” Chem Biol 20, no. 9 (September 19, 2013): 1187–97. https://doi.org/10.1016/j.chembiol.2013.08.004.
       Full Text  Link to Item
    • Choi, Jaeyeon, Ganesan Vaidyanathan, Eftychia Koumarianou, Marek Pruszynski, Tony Lahoutte, and Michael Rod Zalutsky. “Isomeric N-succinimidyl 3-guanidinomethyl-5-[I-131]iodobenzoate (iso-[I-131]SGMIB): A guanidine-containing residualizing agent for radiohalogenation of internalizing biomolecules.” Journal of Labelled Compounds & Radiopharmaceuticals 56 (May 1, 2013): S39–S39.
       Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Marek Pruszynski, Eftychia Koumarianou, Marc Anton Hens, Tony Lahoutte, and Michael Rod Zalutsky. “SFBTMGMB (N-succinimidyl 3-((4-(4-fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate): An SGMIB analogue for labeling internalizing biomolecules with F-18.” Journal of Labelled Compounds & Radiopharmaceuticals 56 (May 1, 2013): S127–S127.
       Link to Item
    • Pruszynski, Marek, Eftychia Koumarianou, Ganesan Vaidyanathan, Hilde Revets, Nick Devoogdt, Tony Lahoutte, and Michael R. Zalutsky. “Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody..” Nucl Med Biol 40, no. 1 (January 2013): 52–59. https://doi.org/10.1016/j.nucmedbio.2012.08.008.
       Full Text  Link to Item
    • Weisenberger, A. G., G. Bonito, S. Lee, J. E. McKisson, A. Gryganskyi, C. D. Reid, M. F. Smith, G. Vaidyanathan, and B. Welch. “A radioisotope based methodology for plant-fungal interactions in the rhizosphere.” Ieee Nuclear Science Symposium Conference Record, January 1, 2013. https://doi.org/10.1109/NSSMIC.2013.6829457.
       Full Text
    • Vaidyanathan, G., B. J. White, D. J. Affleck, X. G. Zhao, P. C. Welsh, D. McDougald, J. Choi, and M. R. Zalutsky. “SIB-DOTA: a trifunctional prosthetic group potentially amenable for multi-modal labeling that enhances tumor uptake of internalizing monoclonal antibodies..” Bioorg Med Chem 20, no. 24 (December 15, 2012): 6929–39. https://doi.org/10.1016/j.bmc.2012.10.025.
       Full Text  Link to Item
    • Slastnikova, Tatiana A., Eftychia Koumarianou, Andrey A. Rosenkranz, Ganesan Vaidyanathan, Tatiana N. Lupanova, Alexander S. Sobolev, and Michael R. Zalutsky. “Modular nanotransporters: a versatile approach for enhancing nuclear delivery and cytotoxicity of Auger electron-emitting 125I..” Ejnmmi Res 2, no. 1 (October 29, 2012). https://doi.org/10.1186/2191-219X-2-59.
       Full Text  Open Access Copy  Link to Item
    • Chin, Bennett B., Anita Hjelemand, Jeremy Rich, Haijing Song, Christopher Lascola, Robert Storms, Roger McLendon, et al. “Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression..” Curr Radiopharm 5, no. 1 (January 2012): 47–58.
       Link to Item
    • Vaidyanathan, Gayathri. “Virus hunters: catching bugs in the field..” Cell 147, no. 6 (December 9, 2011): 1209–11. https://doi.org/10.1016/j.cell.2011.11.037.
       Full Text  Link to Item
    • Vaidyanathan, Gayathri. “Dam controversy: Remaking the Mekong..” Nature 478, no. 7369 (October 19, 2011): 305–7. https://doi.org/10.1038/478305a.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Linda Grasfeder, Michael R. Zalutsky, and Bennett Chin. “An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine..” Appl Radiat Isot 69, no. 10 (October 2011): 1401–6. https://doi.org/10.1016/j.apradiso.2011.05.004.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “Applications of 211At and 223Ra in targeted alpha-particle radiotherapy..” Curr Radiopharm 4, no. 4 (October 2011): 283–94.
       Link to Item
    • Vaidyanathan, Gayathri. “Apes in Africa: The cultured chimpanzees..” Nature 476, no. 7360 (August 17, 2011): 266–69. https://doi.org/10.1038/476266a.
       Full Text  Link to Item
    • Vaidyanathan, Gayatri, Nuttapong Ngamphaiboon, and Francisco J. Hernandez-Ilizaliturri. “Clinical spectrum and prognosis of follicular lymphoma with blastoid transformation: case series and a review of the literature..” Ann Hematol 90, no. 8 (August 2011): 955–62. https://doi.org/10.1007/s00277-011-1162-y.
       Full Text  Link to Item
    • Irikefe, Vivienne, Gayathri Vaidyanathan, Linda Nordling, Aimable Twahirwa, Esther Nakkazi, and Richard Monastersky. “Science in Africa: The view from the front line..” Nature 474, no. 7353 (June 29, 2011): 556–59. https://doi.org/10.1038/474556a.
       Full Text  Link to Item
    • Vaidyanathan, Gayathri. “Science in Africa: The wheat stalker..” Nature 474, no. 7353 (June 29, 2011): 563–65. https://doi.org/10.1038/474563a.
       Full Text  Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Applications of ²¹¹AT and ²²³RA in targeted alpha-particle radiotherapy.” Current Radiopharmaceuticals 4, no. 4 (2011): 283–94.
    • Vaidyanathan, Ganesan, Benjamin White, Donna J. Affleck, Darryl McDougald, and Michael R. Zalutsky. “Radioiodinated O(6)-Benzylguanine derivatives containing an azido function..” Nucl Med Biol 38, no. 1 (January 2011): 77–92. https://doi.org/10.1016/j.nucmedbio.2010.07.006.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Darryl McDougald, Donna J. Affleck, and Michael R. Zalutsky. “A tin precursor of SGMIB potentially useful in the direct modification of peptides and proteins before radiohalogenation.” Journal of Labelled Compounds & Radiopharmaceuticals 54 (January 1, 2011): S64–S64.
       Link to Item
    • Hens, Marc, Ganesan Vaidyanathan, Xiao-Guang Zhao, Darell D. Bigner, and Michael R. Zalutsky. “Anti-EGFRvIII monoclonal antibody armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands..” Nucl Med Biol 37, no. 7 (October 2010): 741–50. https://doi.org/10.1016/j.nucmedbio.2010.04.020.
       Full Text  Link to Item
    • Kato, Yukinari, Ganesan Vaidyanathan, Mika Kato Kaneko, Kazuhiko Mishima, Nidhi Srivastava, Vidyalakshmi Chandramohan, Charles Pegram, et al. “Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas..” Nucl Med Biol 37, no. 7 (October 2010): 785–94. https://doi.org/10.1016/j.nucmedbio.2010.03.010.
       Full Text  Link to Item
    • Vaidyanathan, G., and M. G. Fakih. “A case of curative-intent hepatectomy for colon cancer metastatic to the scapula and liver..” Anticancer Res 30, no. 2 (February 2010): 677–79.
       Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Xiao-Guang Zhao, Stephen T. Keir, and Michael R. Zalutsky. “[Lu]-DOTA-Tyr-octreotate: A Potential Targeted Radiotherapeutic for the Treatment of Medulloblastoma..” Curr Radiopharm 3, no. 1 (2010): 29–36. https://doi.org/10.2174/1874471011003010029.
       Full Text  Link to Item
    • Vaidyanathan, Gayatri, Adrienne Groman, Gregory Wilding, and Marwan G. Fakih. “Stop and go FOLFOX plus bevacizumab chemotherapy in the first-line treatment of metastatic colorectal cancer..” Oncology 79, no. 1–2 (2010): 67–71. https://doi.org/10.1159/000319549.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Haijing Song, Donna Affleck, Darryl L. McDougald, Robert W. Storms, Michael R. Zalutsky, and Bennett B. Chin. “Targeting aldehyde dehydrogenase: a potential approach for cell labeling..” Nucl Med Biol 36, no. 8 (November 2009): 919–29. https://doi.org/10.1016/j.nucmedbio.2009.08.001.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Emmanuelle Jestin, Tove Olafsen, Anna M. Wu, and Michael R. Zalutsky. “Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK..” Nucl Med Biol 36, no. 6 (August 2009): 671–80. https://doi.org/10.1016/j.nucmedbio.2009.04.002.
       Full Text  Link to Item
    • Hens, Marc, Ganesan Vaidyanathan, Phil Welsh, and Michael R. Zalutsky. “Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: in vitro comparison of acyclic and macrocyclic ligands..” Nucl Med Biol 36, no. 2 (February 2009): 117–28. https://doi.org/10.1016/j.nucmedbio.2008.11.001.
       Full Text  Link to Item
    • Vaidyanathan, G., B. White, D. Affleck, X. Zhao, P. Welsh, and M. Zalutsky. “DOTA-SIB, A TRIFUNCTIONAL PROSTHETIC GROUP FOR MULTI-MODAL LABELING.” Journal of Labelled Compounds & Radiopharmaceuticals 52 (January 1, 2009): S70–S70.
       Link to Item
    • Vaidyanathan, Ganesan, Benjamin J. White, and Michael R. Zalutsky. “Propargyl 4-[F]fluorobenzoate: A Putatively More Stable Prosthetic group for the Fluorine-18 Labeling of Biomolecules via Click Chemistry..” Curr Radiopharm 2, no. 1 (January 1, 2009): 63–74.
       Link to Item
    • Vaidyanathan, G. “Meta-iodobenzylguanidine and analogues: chemistry and biology..” Q J Nucl Med Mol Imaging 52, no. 4 (December 2008): 351–68.
       Link to Item
    • Simmons, Kirk, John Kinney, Aaron Owens, Daniel A. Kleier, Karen Bloch, Dave Argentar, Alicia Walsh, and Ganesh Vaidyanathan. “Practical outcomes of applying ensemble machine learning classifiers to High-Throughput Screening (HTS) data analysis and screening..” J Chem Inf Model 48, no. 11 (November 2008): 2196–2206. https://doi.org/10.1021/ci800164u.
       Full Text  Link to Item
    • Sun, C., A. Dobi, A. Mohamed, H. Li, R. L. Thangapazham, B. Furusato, S. Shaheduzzaman, et al. “TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation..” Oncogene 27, no. 40 (September 11, 2008): 5348–53. https://doi.org/10.1038/onc.2008.183.
       Full Text  Link to Item
    • Rosenkranz, Andrey A., Ganesan Vaidyanathan, Oscar R. Pozzi, Vladimir G. Lunin, Michael R. Zalutsky, and Alexander S. Sobolev. “Engineered modular recombinant transporters: application of new platform for targeted radiotherapeutic agents to alpha-particle emitting 211 At..” Int J Radiat Oncol Biol Phys 72, no. 1 (September 1, 2008): 193–200. https://doi.org/10.1016/j.ijrobp.2008.05.055.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “Astatine Radiopharmaceuticals: Prospects and Problems..” Curr Radiopharm 1, no. 3 (September 1, 2008).
       Link to Item
    • Simmons, Kirk, John Kinney, Aaron Owens, Dan Kleier, Karen Bloch, Dave Argentar, Alicia Walsh, and Ganesh Vaidyanathan. “Comparative study of machine-learning and chemometric tools for analysis of in-vivo high-throughput screening data..” J Chem Inf Model 48, no. 8 (August 2008): 1663–68. https://doi.org/10.1021/ci800142d.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Joseph Norman, Susan O’Dorisio, and Michael R. Zalutsky. “A radioiodinated MIBG-octreotate conjugate exhibiting enhanced uptake and retention in SSTR2-expressing tumor cells..” Bioconjug Chem 18, no. 6 (November 2007): 2122–30. https://doi.org/10.1021/bc700240r.
       Full Text  Link to Item
    • Zalutsky, Michael R., David A. Reardon, Oscar R. Pozzi, Ganesan Vaidyanathan, and Darell D. Bigner. “Targeted alpha-particle radiotherapy with 211At-labeled monoclonal antibodies..” Nucl Med Biol 34, no. 7 (October 2007): 779–85. https://doi.org/10.1016/j.nucmedbio.2007.03.007.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Kevin L. Alston, Xiao-Guang Zhao, Marc Hens, Duncan H. Hunter, John Babich, and Michael R. Zalutsky. “A kit method for the high level synthesis of [211At]MABG..” Bioorg Med Chem 15, no. 10 (May 15, 2007): 3430–36. https://doi.org/10.1016/j.bmc.2007.03.016.
       Full Text  Link to Item
    • Park, Jae, Gayathri Vaidyanathan, Bhag Singh, and Radhey S. Gupta. “Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase..” Protein J 26, no. 3 (April 2007): 203–12. https://doi.org/10.1007/s10930-006-9062-z.
       Full Text  Link to Item
    • Vaidyanathan, G., D. J. Affleck, K. L. Alston, and M. R. Zalutsky. “A tin precursor for the synthesis of no-carrier-added [*I]MIBG and [²¹¹At]MABG.” Journal of Labelled Compounds and Radiopharmaceuticals 50, no. 3 (March 1, 2007): 177–82. https://doi.org/10.1002/jlcr.1243.
       Full Text
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides..” Nat Protoc 2, no. 2 (2007): 282–86. https://doi.org/10.1038/nprot.2007.20.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Kevin L. Alston, Darrel D. Bigner, and Michael R. Zalutsky. “Nepsilon-(3-[*I]Iodobenzoyl)-Lys5-Nalpha-maleimido-Gly1-GEEEK ([*I]IB-Mal-D-GEEEK): a radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies..” Bioconjug Chem 17, no. 4 (July 2006): 1085–92. https://doi.org/10.1021/bc0600766.
       Full Text  Link to Item
    • Shankar, Sriram, Michael R. Zalutsky, Henry Friedman, and Ganesan Vaidyanathan. “Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine..” Nucl Med Biol 33, no. 3 (April 2006): 399–407. https://doi.org/10.1016/j.nucmedbio.2005.12.015.
       Full Text  Link to Item
    • Shankar, Sriram, Ganesan Vaidyanathan, Chien-Tsun Kuan, Darell D. Bigner, and Michael R. Zalutsky. “Antiepidermal growth factor variant III scFv fragment: effect of radioiodination method on tumor targeting and normal tissue clearance..” Nucl Med Biol 33, no. 1 (January 2006): 101–10. https://doi.org/10.1016/j.nucmedbio.2005.08.004.
       Full Text  Link to Item
    • Vaidyanathan, G., D. J. Affleck, M. Schottelius, H. Wester, H. S. Friedman, and M. R. Zalutsky. “Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor..” Bioconjug Chem 17, no. 1 (January 2006): 195–203. https://doi.org/10.1021/bc0502560.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “Preparation of N-succinimidyl 3-[*I]iodobenzoate: an agent for the indirect radioiodination of proteins..” Nat Protoc 1, no. 2 (2006): 707–13. https://doi.org/10.1038/nprot.2006.99.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “Synthesis of N-succinimidyl 4-[18F]fluorobenzoate, an agent for labeling proteins and peptides with 18F..” Nat Protoc 1, no. 4 (2006): 1655–61. https://doi.org/10.1038/nprot.2006.264.
       Full Text  Link to Item
    • Shankar, Sriram, Michael R. Zalutsky, and Ganesan Vaidyanathan. “O6-3-[125I]iodobenzyl-2'-deoxyguanosine ([125I]IBdG): synthesis and evaluation of its usefulness as an agent for quantification of alkylguanine-DNA alkyltransferase (AGT)..” Bioorg Med Chem 13, no. 12 (June 2, 2005): 3889–98. https://doi.org/10.1016/j.bmc.2005.04.014.
       Full Text  Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “No-carrier-added synthesis of a 4-methyl-substituted meta-iodobenzylguanidine analogue..” Appl Radiat Isot 62, no. 3 (March 2005): 435–40. https://doi.org/10.1016/j.apradiso.2004.07.001.
       Full Text  Link to Item
    • Vaidyanathan, G. “Astatine-211 Labeled Radiopharmaceuticals, invited.” Transactions of the American Nuclear Society 91 (December 1, 2004).
    • Vaidyanathan, Ganesan, Abraham Boskovitz, Sriram Shankar, and Michael R. Zalutsky. “Radioiodine and 211At-labeled guanidinomethyl halobenzoyl octreotate conjugates: potential peptide radiotherapeutics for somatostatin receptor-positive cancers..” Peptides 25, no. 12 (December 2004): 2087–97. https://doi.org/10.1016/j.peptides.2004.08.018.
       Full Text  Link to Item
    • Shankar, Sriram, Ganesan Vaidyanathan, Donna J. Affleck, Katia Peixoto, Darell D. Bigner, and Michael R. Zalutsky. “Evaluation of an internalizing monoclonal antibody labeled using N-succinimidyl 3-[131I]iodo-4-phosphonomethylbenzoate ([131I]SIPMB), a negatively charged substituent bearing acylation agent..” Nucl Med Biol 31, no. 7 (October 2004): 909–19. https://doi.org/10.1016/j.nucmedbio.2004.04.007.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Philip C. Welsh, Katia C. Vitorello, Stacey Snyder, Henry S. Friedman, and Michael R. Zalutsky. “A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells..” Eur J Nucl Med Mol Imaging 31, no. 10 (October 2004): 1362–70. https://doi.org/10.1007/s00259-004-1596-8.
       Full Text  Link to Item
    • Kumar, Y Ravindra, G. Ramulu, V. V. Vevakanand, Gopal Vaidyanathan, Keesari Srinivas, M Kishore Kumar, K. Mukkanti, M Satyanarayana Reddy, S. Venkatraman, and M. V. Suryanarayana. “A validated chiral HPLC method for the enantiomeric separation of tolterodine tartarate..” J Pharm Biomed Anal 35, no. 5 (September 3, 2004): 1279–85. https://doi.org/10.1016/j.jpba.2004.03.026.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Kevin L. Alston, Philip Welsh, and Michael R. Zalutsky. “Catabolism of 4-fluoro-3-iodobenzylguanidine and meta-iodobenzylguanidine by SK-N-SH neuroblastoma cells..” Nucl Med Commun 25, no. 9 (September 2004): 947–55.
       Link to Item
    • Boyd, Marie, Robert J. Mairs, W Nicol Keith, Susan C. Ross, Philip Welsh, Gamal Akabani, Jonathan Owens, et al. “An efficient targeted radiotherapy/gene therapy strategy utilising human telomerase promoters and radioastatine and harnessing radiation-mediated bystander effects..” J Gene Med 6, no. 8 (August 2004): 937–47. https://doi.org/10.1002/jgm.578.
       Full Text  Link to Item
    • Vaidyanathan, Govindan, Mary J. Cismowski, Guoshun Wang, Timothy S. Vincent, Kevin D. Brown, and Stephen M. Lanier. “The Ras-related protein AGS1/RASD1 suppresses cell growth..” Oncogene 23, no. 34 (July 29, 2004): 5858–63. https://doi.org/10.1038/sj.onc.1207774.
       Full Text  Link to Item
    • Vaidyanathan, Ganesh. “InfoEvolve: moving from data to knowledge using information theory and genetic algorithms..” Ann N Y Acad Sci 1020 (May 2004): 227–38. https://doi.org/10.1196/annals.1310.019.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Sriram Shankar, Donna J. Affleck, Kevin Alston, Joseph Norman, Philip Welsh, Holly LeGrand, and Michael R. Zalutsky. “Meta-iodobenzylguanidine derivatives containing a second guanidine moiety..” Bioorg Med Chem 12, no. 7 (April 1, 2004): 1649–56. https://doi.org/10.1016/j.bmc.2004.01.026.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Joseph Norman, Phil Welsh, Wenge Liu, Stewart P. Johnson, Henry S. Friedman, and Michael R. Zalutsky. “O6-3-[131I]iodobenzylguanine: improved synthesis and further evaluation of a potential agent for imaging of alkylguanine-DNA alkyltransferase..” Bioconjug Chem 15, no. 2 (March 2004): 402–8. https://doi.org/10.1021/bc0341977.
       Full Text  Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Imaging drug resistance with radiolabeled molecules..” Curr Pharm Des 10, no. 24 (2004): 2965–79. https://doi.org/10.2174/1381612043383449.
       Full Text  Link to Item
    • Vivekanand, V. V., D. Sreenivas Rao, G. Vaidyanathan, N. M. Sekhar, S. Avijit Kelkar, and P. Ramachandra Puranik. “A validated LC method for imatinib mesylate..” J Pharm Biomed Anal 33, no. 5 (December 4, 2003): 879–89. https://doi.org/10.1016/s0731-7085(03)00419-9.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Darell D. Bigner, and Michael R. Zalutsky. “N-succinimidyl 3-[211At]astato-4-guanidinomethylbenzoate: an acylation agent for labeling internalizing antibodies with alpha-particle emitting 211At..” Nucl Med Biol 30, no. 4 (May 2003): 351–59.
       Link to Item
    • Vaidyanathan, Ganesan, Henry S. Friedman, Donna J. Affleck, Margaret Schottelius, Hans-Jürgen Wester, and Michael R. Zalutsky. “Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts..” Clin Cancer Res 9, no. 5 (May 2003): 1868–76.
       Link to Item
    • Shankar, Sriram, Ganesan Vaidyanathan, Donna Affleck, Phillip C. Welsh, and Michael R. Zalutsky. “N-succinimidyl 3-[(131)I]iodo-4-phosphonomethylbenzoate ([(131)I]SIPMB), a negatively charged substituent-bearing acylation agent for the radioiodination of peptides and mAbs..” Bioconjug Chem 14, no. 2 (March 2003): 331–41. https://doi.org/10.1021/bc025636p.
       Full Text  Link to Item
    • Shankar, S., G. Vaidyanathan, D. J. Affleck, P. Welsh, H. LeGrand, and M. R. Zalutsky. “Negatively charged substituent-bearing acylation agent for the radiohalogenation of mAbs..” Journal of Nuclear Medicine 43, no. 5 (May 1, 2002): 366P-366P.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, P. Welsh, M. Schottelius, H. Wester, J. A. Norman, K. L. Alston, and M. R. Zalutsky. “Synthesis and in vitro evaluation of glycated octreotate conjugates labeled with radioiodine and At-211 via a tin precursor..” Journal of Nuclear Medicine 43, no. 5 (May 1, 2002): 92P-92P.
       Link to Item
    • Dingus, Jane, Bronwyn S. Tatum, Govindan Vaidyanathan, and John D. Hilderbrandt. “Purification of G protein beta gamma from bovine brain..” Methods Enzymol 344 (2002): 194–208. https://doi.org/10.1016/s0076-6879(02)44716-7.
       Full Text  Link to Item
    • Vaidyanathan, Ganesan, Donna J. Affleck, Darell D. Bigner, and Michael R. Zalutsky. “Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate..” Nucl Med Biol 29, no. 1 (January 2002): 1–11.
       Link to Item
    • Vaidyanathan, G., S. Shankar, D. J. Affleck, P. C. Welsh, S. K. Slade, and M. R. Zalutsky. “Biological evaluation of ring- and side-chain-substituted m-iodobenzylguanidine analogues..” Bioconjug Chem 12, no. 5 (September 2001): 798–806.
       Link to Item
    • Vaidyanathan, G., S. Shankar, and M. R. Zalutsky. “Synthesis of ring- and side-chain-substituted m-iodobenzylguanidine analogues..” Bioconjug Chem 12, no. 5 (September 2001): 786–97.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, J. Li, P. Welsh, and M. R. Zalutsky. “A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB)..” Bioconjug Chem 12, no. 3 (May 2001): 428–38.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, C. M. Cavazos, S. P. Johnson, S. Shankar, H. S. Friedman, M. O. Colvin, and M. R. Zalutsky. “Radiolabeled guanine derivatives for the in vivo mapping of O(6)-alkylguanine-DNA alkyltransferase: 6-(4-[(18)F]Fluoro-benzyloxy)-9H-purin-2-ylamine and 6-(3-[(131)I]Iodo-benzyloxy)-9H-purin-2-ylamine..” Bioconjug Chem 11, no. 6 (November 2000): 868–75.
       Link to Item
    • Bardiès, M., and P. Pihet. “Dosimetry and microdosimetry of targeted radiotherapy..” Curr Pharm Des 6, no. 14 (September 2000): 1469–1502. https://doi.org/10.2174/1381612003399176.
       Full Text  Link to Item
    • Zalutsky, M. R., and G. Vaidyanathan. “Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy..” Curr Pharm Des 6, no. 14 (September 2000): 1433–55. https://doi.org/10.2174/1381612003399275.
       Full Text  Link to Item
    • Vaidyanathan, G., D. Affleck, P. Welsh, A. Srinivasan, M. Schmidt, and M. R. Zalutsky. “Radioiodination and astatination of octreotide by conjugation labeling..” Nucl Med Biol 27, no. 4 (May 2000): 329–37.
       Link to Item
    • Vaidyanathan, G., D. Affleck, P. Welsh, A. Srinivasan, M. Schmidt, and M. R. Zalutsky. “Radioiodination and astatination of octreotide by conjugation labeling.” Journal of Inorganic Biochemistry 78, no. 3 (February 29, 2000): 329–37.
    • Vaidyanathan, G., and M. R. Zalutsky. “Low molecular weight radiopharmaceuticals: Radiohalogenated MIBG and IUdR analogues..” Abstracts of Papers of the American Chemical Society 217 (March 21, 1999): U41–U41.
       Link to Item
    • Vaidyanathan, G., A. Srinivasan, D. J. Affleck, P. C. Welsh, S. K. Slade, M. A. Schmidt, and M. R. Zalutsky. “Octreotide analogues labeled with radioiodine and astatine-211.” Journal of Labelled Compounds and Radiopharmaceuticals 42, no. SUPPL. 1 (January 1, 1999).
    • Vaidyanathan, G., M. R. Zalutsky, and T. R. DeGrado. “Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine..” Bioconjug Chem 9, no. 6 (November 1998): 758–64. https://doi.org/10.1021/bc980037x.
       Full Text  Link to Item
    • Wang, L., J. Kristensen, and D. E. Ruffner. “Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules..” Bioconjug Chem 9, no. 6 (November 1998): 749–57. https://doi.org/10.1021/bc980034k.
       Full Text  Link to Item
    • Walicka, M. A., G. Vaidyanathan, M. R. Zalutsky, S. J. Adelstein, and A. I. Kassis. “Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211..” Radiat Res 150, no. 3 (September 1998): 263–68.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Preparation of 5-[131I]iodo- and 5-[211At]astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil by a halodestannylation reaction..” Nucl Med Biol 25, no. 5 (July 1998): 487–96.
       Link to Item
    • Cunningham, S. H., R. J. Mairs, T. E. Wheldon, P. C. Welsh, G. Vaidyanathan, and M. R. Zalutsky. “Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions..” Br J Cancer 77, no. 12 (June 1998): 2061–68. https://doi.org/10.1038/bjc.1998.348.
       Full Text  Open Access Copy  Link to Item
    • Berry, C. R., G. Vaidyanathan, P. E. Fisher, M. R. Zalutsky, R. E. Coleman, and T. R. DeGrado. “Myocardial kinetics of meta-[I-131]iodobenzylguanidine in an adriamycin cardiomyopathy rat model..” Journal of Nuclear Medicine 39, no. 5 (May 1, 1998): 47P-47P.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Targeted therapy using astatinated radiopharmaceuticals..” Abstracts of Papers of the American Chemical Society 215 (April 2, 1998): U946–U946.
       Link to Item
    • DeGrado, T. R., M. R. Zalutsky, R. E. Coleman, and G. Vaidyanathan. “Effects of specific activity on meta-[(131)I]iodobenzylguanidine kinetics in isolated rat heart..” Nucl Med Biol 25, no. 1 (January 1998): 59–64.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “Method for radioiodination of proteins using N-succinimidyl 3-hydroxy-4-iodobenzoate..” Bioconjug Chem 8, no. 5 (September 1997): 724–29. https://doi.org/10.1021/bc9700502.
       Full Text  Link to Item
    • Larsen, R. H., G. Vaidyanathan, and M. R. Zalutsky. “Cytotoxicity of alpha-particle-emitting 5-[211At]astato-2'-deoxyuridine in human cancer cells..” Int J Radiat Biol 72, no. 1 (July 1997): 79–90.
       Link to Item
    • Vaidyanathan, G., X. -. G. Zhao, R. H. Larsen, and M. R. Zalutsky. “3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells.” British Journal of Cancer 76, no. 2 (July 1997): 226–33. https://doi.org/10.1038/bjc.1997.366.
       Full Text
    • Vaidyanathan, Ganesan, and Michael R. Zalutsky. “A New Route to Guanidines from Bromoalkanes.” The Journal of Organic Chemistry 62, no. 14 (July 1997): 4867–69. https://doi.org/10.1021/jo9704164.
       Full Text
    • DeGrado, T. R., M. R. Zalutsky, and G. Vaidyanathan. “Mechanisms of uptake in isolated rat heart of potential radiotherapeutic agent [At-211]meta-astatobenzylguanidine (MABG)..” Journal of Nuclear Medicine 38, no. 5 (May 1, 1997): 106–106.
       Link to Item
    • Kassis, A. I., M. A. Walicka, G. Vaidyanathan, M. R. Zalutsky, and S. J. Adelstein. “Survival and DNA damage in V79 cells exposed to the alpha emitters 5-[At-211]astato-2'-deoxy-uridine and [At-211]astatide..” Journal of Nuclear Medicine 38, no. 5 (May 1, 1997): 964–964.
       Link to Item
    • Vaidyanathan, G., X. G. Zhao, D. K. Strickland, and M. R. Zalutsky. “No-carrier-added iodine-131-FIBG: evaluation of an MIBG analog..” J Nucl Med 38, no. 2 (February 1997): 330–34.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Fluorine-18-labeled [Nle4,D-Phe7]-alpha-MSH, an alpha-melanocyte stimulating hormone analogue..” Nucl Med Biol 24, no. 2 (February 1997): 171–78.
       Link to Item
    • Vaidyanathan, G., X. G. Zhao, R. H. Larsen, and M. R. Zalutsky. “3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells..” Br J Cancer 76, no. 2 (1997): 226–33. https://doi.org/10.1038/bjc.1997.366.
       Full Text  Open Access Copy  Link to Item
    • Vaidyanathan, G., X. G. Zhao, R. H. Larsen, and M. R. Zalutsky. “3-[²¹¹At]astato-4-fluorobenzylguanidine: A potential therapeutic agent with prolonged retention by neuroblastoma cells.” British Journal of Cancer 76, no. 2 (1997): 226–33.
    • Vaidyanathan, G., and M. R. Zalutsky. “Targeted therapy using alpha emitters..” Phys Med Biol 41, no. 10 (October 1996): 1915–31. https://doi.org/10.1088/0031-9155/41/10/005.
       Full Text  Link to Item
    • Vaidyanathan, G., H. S. Friedman, S. T. Keir, and M. R. Zalutsky. “Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model..” Nucl Med Biol 23, no. 6 (August 1996): 851–56.
       Link to Item
    • DeGrado, T. R., M. R. Zalutsky, R. E. Coleman, and G. Vaidyanathan. “Effects of specific activity on uptake and retention of metaiodobenzylguanidine (MIBG) in the heart: Revisited.” Journal of Nuclear Medicine 37, no. 5 (May 1, 1996): 701–701.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, P. C. Welsh, S. A. Slade, K. L. Alston, and M. R. Zalutsky. “Fluorine-18 labeling of [Nle(4),D-Phe(7)]-alpha-MSH, an alpha-melanocyte stimulating hormone (alpha-MSH) analogue..” Journal of Nuclear Medicine 37, no. 5 (May 1, 1996): 875–875.
       Link to Item
    • Vaidyanathan, G., H. S. Friedman, S. T. Keir, and M. R. Zalutsky. “Localisation of [131I]MIBG in nude mice bearing SK-N-SH human neuroblastoma xenografts: effect of specific activity..” Br J Cancer 73, no. 10 (May 1996): 1171–77. https://doi.org/10.1038/bjc.1996.226.
       Full Text  Open Access Copy  Link to Item
    • Vaidyanathan, G., H. S. Friedman, S. T. Keir, and M. R. Zalutsky. “Meta-[At-211]astatobenzylguanidine (MABG): In vivo evaluation in an athymic mouse human neuroblastoma xenograft model..” Journal of Nuclear Medicine 37, no. 5 (May 1, 1996): 236–236.
       Link to Item
    • Zweit, J., M. Flower, A. Brown, P. Carnochan, S. Luthra, F. Brady, V. Pike, et al. “Iodine-120-mIBG: Production and NCA labelling of a new PET radiotracer..” Journal of Nuclear Medicine 37, no. 5 (May 1, 1996): 874–874.
       Link to Item
    • Vaidyanathan, G., R. H. Larsen, and M. R. Zalutsky. “5-[211 At]astato-2'-deoxyuridine, an alpha particle-emitting endoradiotherapeutic agent undergoing DNA incorporation..” Cancer Res 56, no. 6 (March 15, 1996): 1204–9.
       Link to Item
    • Vaidyanathan, G., R. H. Larsen, and M. R. Zalutsky. “Particle-emitting endoradiotherapeutic agent undergoing DNA incorporation.” Cancer Research 56, no. 6 (March 15, 1996): 1204–9.
    • Vaidyanathan, G., R. H. Larsen, and M. R. Zalutsky. “5-[At-211]astato-2'-deoxyuridine, an alpha-particle-emitting endoradiotherapeutic agent undergoing DNA incorporation.” Cancer Research 56, no. 6 (March 15, 1996): 1204–9.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “No-carrier-added (4-fluoro-3-[131I]iodobenzyl)guanidine and (3-[211At]astato-4-fluorobenzyl)guanidine..” Bioconjug Chem 7, no. 1 (January 1996): 102–7. https://doi.org/10.1021/bc950078i.
       Full Text  Link to Item
    • Reist, C. J., G. E. Archer, S. N. Kurpad, C. J. Wikstrand, G. Vaidyanathan, M. C. Willingham, D. K. Moscatello, A. J. Wong, D. D. Bigner, and M. R. Zalutsky. “Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts..” Cancer Res 55, no. 19 (October 1, 1995): 4375–82.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Fluorine-18 labeled chemotactic peptides: a potential approach for the PET imaging of bacterial infection..” Nucl Med Biol 22, no. 6 (August 1995): 759–64.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “Validation of 4-[fluorine-18]fluoro-3-iodobenzylguanidine as a positron-emitting analog of MIBG..” J Nucl Med 36, no. 4 (April 1995): 644–50.
       Link to Item
    • Degrado, T. R., M. R. Zalutsky, and G. Vaidyanathan. “Uptake mechanisms of meta-[123I]iodobenzylguanidine in isolated rat heart..” Nucl Med Biol 22, no. 1 (January 1995): 1–12.
       Link to Item
    • Johnson, E. L., T. G. Turkington, R. J. Jaszczak, D. R. Gilland, G. Vaidyanathan, K. L. Greer, R. E. Coleman, and M. R. Zalutsky. “Quantitation of 211At in small volumes for evaluation of targeted radiotherapy in animal models..” Nucl Med Biol 22, no. 1 (January 1995): 45–54.
       Link to Item
    • Mairs, R. J., J. Russell, S. Cunningham, J. A. O’Donoghue, M. N. Gaze, J. Owens, G. Vaidyanathan, and M. R. Zalutsky. “Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [131I]meta-iodobenzylguanidine: implications for the targeted radiotherapy of neuroblastoma..” Eur J Cancer 31A, no. 4 (1995): 576–81. https://doi.org/10.1016/0959-8049(95)00052-k.
       Full Text  Link to Item
    • Strickland, D. K., G. Vaidyanathan, H. S. Friedman, and M. R. Zalutsky. “Meta-[131I]iodobenzylguanidine uptake and meta-[211At]astatobenzylguanidine treatment in human medulloblastoma cell lines..” J Neurooncol 25, no. 1 (1995): 9–17.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “No-carrier-added meta-[123I]iodobenzylguanidine: synthesis and preliminary evaluation..” Nucl Med Biol 22, no. 1 (January 1995): 61–64.
       Link to Item
    • Strickland, D. K., G. Vaidyanathan, and M. R. Zalutsky. “Cytotoxicity of alpha-particle-emitting m-[211At]astatobenzylguanidine on human neuroblastoma cells..” Cancer Res 54, no. 20 (October 15, 1994): 5414–19.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “(4-[18F]fluoro-3-iodobenzyl)guanidine, a potential MIBG analogue for positron emission tomography..” J Med Chem 37, no. 21 (October 14, 1994): 3655–62. https://doi.org/10.1021/jm00047a022.
       Full Text  Link to Item
    • Page, R. L., P. K. Garg, G. Vaidyanathan, and M. R. Zalutsky. “Preclinical evaluation and PET imaging of 18F-labeled Mel-14 F(ab')2 fragment in normal dogs..” Nucl Med Biol 21, no. 7 (October 1994): 911–19.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Improved synthesis of N-succinimidyl 4-[18F]fluorobenzoate and its application to the labeling of a monoclonal antibody fragment..” Bioconjug Chem 5, no. 4 (July 1994): 352–56.
       Link to Item
    • Vaidyanathan, G., D. K. Strickland, and M. R. Zalutsky. “Meta-[211At]astatobenzylguanidine: further evaluation of a potential therapeutic agent..” Int J Cancer 57, no. 6 (June 15, 1994): 908–13. https://doi.org/10.1002/ijc.2910570622.
       Full Text  Link to Item
    • DEGRADO, T. R., M. R. ZALUTSKY, D. J. AFFLECK, and G. VAIDYANATHAN. “MECHANISTIC STUDIES OF METAIODOBENZYLGUANIDINE (METAIODOBENZYLGUANIDINE) UPTAKE AND RETENTION IN ISOLATED RAT-HEART.” Journal of Nuclear Medicine 35, no. 5 (May 1, 1994): P57–P57.
       Link to Item
    • JOHNSON, E. L., T. G. TURKINGTON, R. J. JASZCZAK, M. R. ZALUTSKY, D. R. GILLAND, G. VAIDYANATHAN, K. L. GREER, and R. E. COLEMAN. “QUANTITATIVE IMAGING OF AT-211 RADIOTHERAPEUTIC AGENTS IN SMALL VOLUMES.” Journal of Nuclear Medicine 35, no. 5 (May 1, 1994): P180–P180.
       Link to Item
    • VAIDYANATHAN, G., D. J. AFFLECK, S. A. SLADE, P. C. WELSH, and M. R. ZALUTSKY. “SYNTHESIS AND PRELIMINARY EVALUATION OF 4-[F-18]FLUORO-3-IODOBENZYLGUANIDINE (FIBG) - A METAIODOBENZYLGUANIDINE ANALOG FOR PET.” Journal of Nuclear Medicine 35, no. 5 (May 1, 1994): P248–P248.
       Link to Item
    • Mairs, R. J., M. N. Gaze, D. G. Watson, G. G. Skellern, P. Constable, K. McKellar, J. Owens, G. Vaidyanathan, and M. R. Zalutsky. “Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine..” Nucl Med Commun 15, no. 4 (April 1994): 268–74.
       Link to Item
    • Shepherd, N. S., B. D. Pfrogner, J. N. Coulby, S. L. Ackerman, G. Vaidyanathan, R. H. Sauer, T. C. Balkenhol, and N. Sternberg. “Preparation and screening of an arrayed human genomic library generated with the P1 cloning system..” Proc Natl Acad Sci U S A 91, no. 7 (March 29, 1994): 2629–33. https://doi.org/10.1073/pnas.91.7.2629.
       Full Text  Link to Item
    • Gaze, M. N., R. J. Mairs, G. Vaidyanathan, and M. R. Zalutsky. “Synthesis of carrier-free 131I-meta-iodobenzyl-guanidine by novel routes to enhance therapeutic efficiency in neuroblastoma..” Prog Clin Biol Res 385 (1994): 347–53.
       Link to Item
    • Vaidyanathan, G., D. A. Affleck, P. Welsh, and M. R. Zalutsky. “Fluorine-18 labeled chemotactic peptide: A potential agent for the PET imaging of focal infection.” Journal of Labelled Compounds and Radiopharmaceuticals 35 (January 1, 1994): 365–67.
    • Vaidyanathan, G., D. Affleck, and M. R. Zalutsky. “Monoclonal antibody F(ab')2 fragment labeled with N-succinimidyl 2,4-dimethoxy-3-halobenzoates: in vivo comparison of iodinated and astatinated fragments..” Nucl Med Biol 21, no. 1 (January 1994): 105–10.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “(4-[¹⁸F]fluoro-3-iodobenzyl)guanidine, a potential mibg analogue for positron emission tomography.” Journal of Medicinal Chemistry 37, no. 21 (1994): 3655–62.
    • Vaidyanathan, G., D. K. Strickland, D. A. Affleck, P. Welsh, and M. R. Zalutsky. “Meta-[²¹¹At]astatobenzylguanidine: Further validation of in vitro and in vivo uptake mechanisms.” Journal of Labelled Compounds and Radiopharmaceuticals 35 (1994): 589–91.
    • DEGRADO, T. R., M. R. ZALUTSKY, D. J. AFFLECK, and G. VAIDYANATHAN. “UPTAKE MECHANISMS OF I-123 METAIODOBENZYLGUANIDINE (METAIODOBENZYLGUANIDINE) IN ISOLATED RAT-HEART.” Circulation 88, no. 4 (October 1, 1993): 355–355.
       Link to Item
    • Turkington, T. G., M. R. Zalutsky, R. J. Jaszczak, P. K. Garg, G. Vaidyanathan, and R. E. Coleman. “Measuring astatine-211 distributions with SPECT..” Phys Med Biol 38, no. 8 (August 1993): 1121–30. https://doi.org/10.1088/0031-9155/38/8/010.
       Full Text  Link to Item
    • TURKINGTON, T. G., M. R. ZALUTSKY, R. J. JASZCZAK, P. GARG, G. VAIDYANATHAN, and R. E. COLEMAN. “MEASURING ASTATINE-211 DISTRIBUTIONS WITH SPECT.” Journal of Nuclear Medicine 34, no. 5 (May 1, 1993): P191–P191.
       Link to Item
    • VAIDYANATHAN, G., C. HARRISON, P. WELSH, D. AFFLECK, and M. R. ZALUTSKY. “INVITRO CYTOTOXICITY OF M-[AT-211]ASTATOBENZYLGUANIDINE (MABG).” Journal of Nuclear Medicine 34, no. 5 (May 1, 1993): P218–P218.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “No-carrier-added synthesis of meta-[131I]iodobenzylguanidine..” Appl Radiat Isot 44, no. 3 (March 1993): 621–28.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “Radioiodination of proteins using N-succinimidyl 4-hydroxy-3-iodobenzoate..” Bioconjug Chem 4, no. 1 (January 1993): 78–84.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “1-(m-[211At]astatobenzyl)guanidine: synthesis via astato demetalation and preliminary in vitro and in vivo evaluation..” Bioconjug Chem 3, no. 6 (November 1992): 499–503.
       Link to Item
    • Vaidyanathan, G., D. D. Bigner, and M. R. Zalutsky. “Fluorine-18-labeled monoclonal antibody fragments: a potential approach for combining radioimmunoscintigraphy and positron emission tomography..” J Nucl Med 33, no. 8 (August 1992): 1535–41.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Labeling proteins with fluorine-18 using N-succinimidyl 4-[18F]fluorobenzoate..” Int J Rad Appl Instrum B 19, no. 3 (April 1992): 275–81.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “1-(m-[²¹¹At]astatobenzyl)guanidine: Synthesis via astato demetalation and preliminary in vitro and in vivo evaluation.” Bioconjugate Chemistry 3, no. 6 (1992): 499–503.
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “Aromatic acylation reagents for use in the radioiodination of proteins.” Journal of Labelled Compounds and Radiopharmaceuticals 30 (April 5, 1991).
    • Vaidyanathan, G., M. Jay, R. K. Bera, P. R. Mayer, and R. K. Brazzell. “Scintigraphic evaluation of the ocular disposition of 18F-imirestat in rabbits..” Pharm Res 7, no. 11 (November 1990): 1198–1200. https://doi.org/10.1023/a:1015952930541.
       Full Text  Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Radioiodination of antibodies via N-succinimidyl 2,4-dimethoxy-3-(trialkylstannyl)benzoates..” Bioconjug Chem 1, no. 6 (November 1990): 387–93.
       Link to Item
    • Vaidyanathan, G., and M. R. Zalutsky. “Protein radiohalogenation: observations on the design of N-succinimidyl ester acylation agents..” Bioconjug Chem 1, no. 4 (July 1990): 269–73.
       Link to Item
    • GARG, P. K., G. VAIDYANATHAN, S. GARG, and M. R. ZALUTSKY. “RADIOIODINATION AND ASTATINATION OF MONOCLONAL-ANTIBODIES.” Abstracts of Papers of the American Chemical Society 199 (April 22, 1990): 16-NUCL.
       Link to Item
    • Vaidyanathan, G., and J. W. Wilson. “Reaction of Cyclopropanamines with Hypochlorite.” Journal of Organic Chemistry 54, no. 8 (April 1, 1989): 1815–20. https://doi.org/10.1021/jo00269a014.
       Full Text
    • Vaidyanathan, G., and J. W. Wilson. “Decarboxylation of 1-Aminocyclopropanecarboxylic Acid and Its Derivatives.” Journal of Organic Chemistry 54, no. 8 (April 1, 1989): 1810–15. https://doi.org/10.1021/jo00269a013.
       Full Text

  • Conference Papers

    • Minn, Il, Ronnie Mease, Choong Mo Kang, Vivek Kumar, Sangeeta Ray, Mary Brummet, Ana Kiess, Ganesan Vaidyanathan, Michael Zalutsky, and Martin Pomper. “PSMA-targeted alpha therapeutic agent with fast kidney clearance.” In Journal of Nuclear Medicine, Vol. 60. SOC NUCLEAR MEDICINE INC, 2019.
       Link to Item
    • Zhou, Zhengyuan, Darryl McDougald, Nick Devoogdt, Michael Zalutsky, and Ganesan Vaidyanathan. “Fluorine-18 labeling of a single domain antibody fragment with 2,5-dioxopyrrolidin-1-yl 3-(1-(2-(2-(2-(2-[F-18]fluoroethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)-5-(guanidinomethyl)benzoate, an alternative residualizing prosthetic agent..” In Journal of Labelled Compounds & Radiopharmaceuticals, 62:S484–86. WILEY, 2019.
       Link to Item
    • Zhou, Zhengyuan, Michael Zalutsky, and Ganesan Vaidyanathan. “Fluorine-18 labeling of an anti-HER2 sdAb with 6-fluoronicotinyl moiety via the inverse electron-demand Diels-Alder reaction (IEDDAR) including a renal brush border enzyme-cleavable linker.” In Journal of Labelled Compounds & Radiopharmaceuticals, 62:S480–82. WILEY, 2019.
       Link to Item
    • Kang, Choong Mo, Ganesan Vaidyanathan, Darryl McDougald, and Michael Zalutsky. “Simplified At-211-labeling of internalizing proteins by preconjugation with the tin precursor of a residualizing prosthetic agent: Application to an anti-HER2 single domain antibody fragment.” In Journal of Nuclear Medicine, Vol. 59. SOC NUCLEAR MEDICINE INC, 2018.
       Link to Item
    • Mease, Ronnie, Choong Kang, Vivek Kumar, Sangeeta Ray, I. L. Minn, Mary Brummet, Andrew Park, et al. “Small Molecule Radiohalogenated (I-125/At-211), DOTA Containing PSMA Inhibitors: Metal Complexation and Competing Inhibitor Improve Biodistribution in Mice.” In Journal of Nuclear Medicine, Vol. 59. SOC NUCLEAR MEDICINE INC, 2018.
       Link to Item
    • Zhou, Zhengyuan, Nick Devoogdt, Michael Zalutsky, and Ganesan Vaidyanathan. “F-18-labeling of an anti-HER2 sdAb with a renal brush border enzyme-cleavable linker-containing prosthetic agent via a trans-cyclooctene (TCO)-terazine (Tz) inverse electron-demand Diels-Alder reaction (IEDDAR) for reduced renal uptake.” In Journal of Nuclear Medicine, Vol. 59. SOC NUCLEAR MEDICINE INC, 2018.
       Link to Item
    • Chin, Bennett, Thomas Hawk, Douglas Weitzel, Darryl McDougald, Robert Reiman, Gregory Palmer, Michael Zalutsky, and Ganesan Vaidyanathan. “Feasibility of 124I anti-PD-L1 PET/CT imaging in a syngeneic tumor model of breast cancer..” In Journal of Nuclear Medicine, Vol. 58. SOC NUCLEAR MEDICINE INC, 2017.
       Link to Item
    • Zhou, Zhengyuan, Nick Devoogdt, Michael Zalutsky, and Ganesan Vaidyanathan. “Labeling an anti-HER2 VHH with F-18 using a residualizing prosthetic group via strain-promoted click reaction: preliminary evaluation.” In Journal of Nuclear Medicine, Vol. 58. SOC NUCLEAR MEDICINE INC, 2017.
       Link to Item
    • Vaidyanathan, G. V., Z. Zhou, D. McDougald, T. Lahoutte, and M. R. Zalutsky. “Anti-HER2 Single Domain Antibody 2Rs15d Labeled with F-18 Using a Residualizing Label: Preliminary Evaluation.” In European Journal of Nuclear Medicine and Molecular Imaging, 43:S179–S179. SPRINGER, 2016.
       Link to Item
    • Kiess, Ana, Il Minn, Ganesan Vaidyanathan, Robert Hobbs, Anders Josefsson, Colette Shen, Mary Brummet, et al. “[211At]YC-I-27 for PSMA-Targeted Alpha-Particle Radiopharmaceutical Therapy.” In Journal of Nuclear Medicine, Vol. 57. SOC NUCLEAR MEDICINE INC, 2016.
       Link to Item
    • Mease, Ronnie, Ganesan Vaidyanathan, Darryl McGougald, Jaeyeon Choi, Ying Chen, Hassan Shallal, Mary Brummet, et al. “211At-Labeled Small-Molecule PSMA Inhibitors: Effect of Structure on Biodistribution in Mice.” In Journal of Nuclear Medicine, Vol. 57. SOC NUCLEAR MEDICINE INC, 2016.
       Link to Item
    • Vaidyanathan, G., D. McDougald, J. Choi, E. Koumarianou, M. Pruszynski, T. Osada, H. Lyerly, T. Lahoutte, and M. R. Zalutsky. “An Anti-HER2 Nanobody Labeled with 18F Using a Residualizing Label for Assessing HER2 Status.” In European Journal of Nuclear Medicine and Molecular Imaging, 42:S102–S102. SPRINGER, 2015.
       Link to Item
    • Batra, Vandana, Pietro Ranieri, Mehran Makvandi, Matthew Tsang, Catherine Hou, Yimei Li, Ganesan Vaidyanathan, Daniel A. Pryma, and John M. Maris. “Abstract 1610: Development of meta-[211At]astatobenzylguanidine ([211At]MABG) as an alpha particle emitting systemic targeted radiotherapeutic for neuroblastoma.” In Clinical Research (Excluding Clinical Trials). American Association for Cancer Research, 2015. https://doi.org/10.1158/1538-7445.am2015-1610.
       Full Text
    • Batra, Vandana, Mehran Makvandi, Pietro Ranieri, Matthew Tsang, Catherine Hou, Yimei Li, Ganesan Vaidyanathan, John Maris, and Daniel Pryma. “Preclinical development of Meta-[At-211]astatobenzylguanidine ([At-211]MABG) as an alpha particle emitting systemic targeted radiotherapeutic for neuroblastoma (NB)..” In Journal of Nuclear Medicine, Vol. 56. SOC NUCLEAR MEDICINE INC, 2015.
       Link to Item
    • Choi, Jaeyeon, Ganesan Vaidyanathan, Eftychia Koumarianou, Tony Lahoutte, and Michael Zalutsky. “A At-211-labeled nanobody for alpha-particle therapy of HER2-expressing cancers.” In Journal of Nuclear Medicine, Vol. 56. SOC NUCLEAR MEDICINE INC, 2015.
       Link to Item
    • Vaidyanathan, Ganesan, Sri Gururangan, Darell Bigner, and Michael Zalutsky. “PRE-CLINICAL EFFICACY STUDY OF INTRA-THECAL (IT) (LU)-L-177-DOTA-TATE (SOMATOSTATIN ANALOGUE) IN ATHYMIC RATS WITH LEPTOMENINGEAL DISEASE (LMD) FROM MEDULLOBLASTOMA (MBL).” In Neuro Oncology, 16:71–71. OXFORD UNIV PRESS INC, 2014.
       Link to Item
    • Slastnikova, T., E. Koumarianou, A. Rosenkranz, G. Vaidyanathan, M. Zalutsky, and A. Sobolev. “Modular nanotransporters efficiently deliver Auger electron emitters into nuclei of cancer cells.” In Febs Journal, 280:315–16. WILEY-BLACKWELL, 2013.
       Link to Item
    • Chin, Bennett, Linda Grasfeder, Darryl McDougald, and Ganesan Vaidyanathan. “Iodoquine as a potential PET radiolabel for in vivo cell trafficking of leukocyte tumor cell lines.” In Journal of Nuclear Medicine, Vol. 53. SOC NUCLEAR MEDICINE INC, 2012.
       Link to Item
    • Koumarianou, Eftychia, Tatiana Slastnikova, Marek Pruszynski, Xiao-Guang Zhao, Andrey Rosenkranz, Ganesan Vaidyanathan, Alexander Sobolev, and Michael Zalutsky. “Modular nanotransporters: A flexible platform forward for targeted Auger electron therapy.” In Journal of Nuclear Medicine, Vol. 53. SOC NUCLEAR MEDICINE INC, 2012.
       Link to Item
    • Zalutsky, M. R., and G. Vaidyanathan. “TARGETED ALPHA THERAPY.” In Radiotherapy and Oncology, 102:S195–S195. ELSEVIER IRELAND LTD, 2012.
       Link to Item
    • Vaidyanathan, Ganesan, Darryl MacDougald, Linda Grasfeder, Michael Zalutsky, and Bennett Chin. “An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.” In Journal of Nuclear Medicine, Vol. 52. SOC NUCLEAR MEDICINE INC, 2011.
       Link to Item
    • Vaidyanathan, Ganesan, Jianjun Li, Darell D. Bigner, and Michael R. Zalutsky. “TARGETED RADIOTHERAPY OF MEDULLOBLASTOMA USING SOMATOSTATIN RECEPTOR AVID RADIOLABELED PEPTIDES.” In Neuro Oncology, 13:I27–I27. OXFORD UNIV PRESS INC, 2011.
       Link to Item
    • Vaidyanathan, G., B. White, D. J. Affleck, D. McDougald, and M. R. Zalutsky. “Radioiodinated O6-Benzylguanine Analogues Containing an Azido Function.” In European Journal of Nuclear Medicine and Molecular Imaging, 37:S265–S265. SPRINGER, 2010.
       Link to Item
    • Chin, Bennett, Robert Reiman, Haijing Song, and Ganesan Vaidyanathan. “Radiation dose estimates of [123I] and [131I] iodoquine, putative radiotracers targeting cells with high ALDH expression.” In Journal of Nuclear Medicine, Vol. 50. SOC NUCLEAR MEDICINE INC, 2009.
       Link to Item
    • Vaidyanathan, Ganesan, Ronnie Mease, Donna Affleck, Ying Chen, Philip Welsh, Marc Hens, Martin Pomper, and Michael Zalutsky. “An astatine-211 labeled PSMA inhibitor for targeted alpha-particle radiotherapy of prostate carcinoma.” In Journal of Nuclear Medicine, Vol. 50. SOC NUCLEAR MEDICINE INC, 2009.
       Link to Item
    • Barrett, J. A., R. Coleman, M. Morse, N. Borys, J. Kronauge, J. B. Stubbs, H. Mok, et al. “Phase 1 study of radiation dosimetry and clearance of no carrier added 131I-MIBG (ultratrace iobenguane) in 7 carcinoid and 4 pheochromocytoma patients.” In European Journal of Nuclear Medicine and Molecular Imaging, 34:S241–S241. SPRINGER, 2007.
       Link to Item
    • Chin, B. B., R. W. Storms, K. Base, C. Lascola, T. Haystead, M. R. Zalutsky, and G. Vaidyanathan. “[I-125] iodoquine uptake in tumor cell lines with high ALDH expression.” In European Journal of Nuclear Medicine and Molecular Imaging, 34:S222–S222. SPRINGER, 2007.
       Link to Item
    • Gamcsik, Michael P., James B. Springer, Timothy A. Driscoll, Ganesan Vaidyanathan, O Michael Colvin, and Susan M. Ludeman. “Targeted drug delivery for neuroblastoma using MIBG..” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
       Link to Item
    • Vaidyanathan, G., K. L. Alston, P. C. Welsh, and M. R. Zalutsky. “Enhanced cellular retention of an internalizing anti-EGFRvIII monoclonal antibody radioiodinated using LYS5-[*I]iodobenzoyl Gly(1)-maleimido GEEEK ([*I]IB-Mal-D-GEEEK), a prosthetic group containing negatively charged D-glutamates.” In Neuro Oncology, 7:386–386. DUKE UNIV PRESS, 2005.
       Link to Item
    • Vaidyanathan, G., K. Base, and M. R. Zalutsky. “0(6)-{4-(3-[F-18]fluoropropyl)-benzyl}-2 '-deoxyguanosine ([F-18]FPBdG) - Synthesis and evaluation of a potential DNA repair protein 0(6)-alkyguanine-DNA alkyltransferase (AGT) imaging agent..” In Abstracts of Papers of the American Chemical Society, 229:U182–U182. AMER CHEMICAL SOC, 2005.
       Link to Item
    • Boskovitz, A., G. Vaidyanathan, G. E. Archer, H. Ochiai, T. Okamura, J. H. Sampson, D. D. Bigner, and M. R. Zalutsky. “Medulloblastoma neoplastic meningitis targeted radiotherapy with intrathecal alpha-emitter At-211-labeled thymidine analogue.” In Neuro Oncology, 6:403–403. DUKE UNIV PRESS, 2004.
       Link to Item
    • Vaidyanathan, G., A. Boskovitz, H. S. Friedman, D. J. Affleck, and M. R. Zalutsky. “Somatostatin targeted radiotherapeuiccs for medulloblastoma.” In Neuro Oncology, 6:416–416. DUKE UNIV PRESS, 2004.
       Link to Item
    • Vaidyanathan, G., D. J. Affleck, and M. R. Zalutsky. “N-succinimidyl 3-[211AT]astato-4-guanidinomethylbenzoate: An acylation agent for labeling internalizing antibodies with alpha-particle emitting (211)AT..” In Abstracts of Papers of the American Chemical Society, 225:U265–U265. AMER CHEMICAL SOC, 2003.
       Link to Item
    • VAIDYANATHAN, G., D. J. AFFLECK, S. A. SLADE, P. WELSH, and M. R. ZALUTSKY. “NO-CARRIER-ADDED 4-FLUORO-3-IODOBENZYLGUANIDINE LABELED WITH I-131 ([I-131]FIBG) AND F-18 ([F-18]FIBG - POTENTIAL MIBG ANALOGS FOR PET IMAGING AND THERAPY OF NEUROENDOCRINE TUMORS.” In Proceedings of the Xvi International Cancer Congress  Free Papers and Posters, Tomes 1 4, edited by R. S. Rao, M. G. Deo, L. D. Sanghvi, and I. Mittra, 3013–17. MONDUZZI EDITORE, 1994.
       Link to Item
    • Vaidyanathan, G., D. K. Strickland, D. A. Affleck, P. Welsh, and M. R. Zalutsky. “Meta-[²¹¹At]astatobenzylguanidine: Further validation of in vitro and in vivo uptake mechanisms.” In Journal of Labelled Compounds and Radiopharmaceuticals, 35:589–91, 1994.
• Teaching & Mentoring
• 

  Recent Courses

  • MEDPHY 746: Radiopharmaceutical Chemistry 2017

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.