Overview
My research studies the molecular underpinnings of orthopaedic and neurological conditions using preclinical in vivo models, ex vivo microphysiological systems, and behavioral analyses. The goal is to apply these understandings for the development of novel therapeutics to improve human health.
Current Appointments & Affiliations
Assistant Professor of Orthopaedic Surgery
·
2022 - Present
Orthopaedic Surgery,
Clinical Science Departments
Recent Publications
Extensive Periosteal Injury During Fracture Induces Long-Term Pain in Mice.
Journal Article J Orthop Res · June 2025 Bone fractures pose a significant public health challenge, often necessitating surgical interventions to facilitate bone healing and functional recovery. Sensory nerve fibers innervate various compartments of the bone tissue, with the periosteum exhibiting ... Full text Link to item CiteEnabling adenosine signaling to promote aged fracture healing.
Journal Article NPJ Regen Med · April 9, 2025 Bone fractures and related complications are a significant concern for older adults, particularly with the growing aging population. Therapeutic interventions that promote bone tissue regeneration are attractive for geriatric fracture repair. Extracellular ... Full text Link to item CiteSpecialized pro-resolving mediator Maresin 1 attenuates pain in a mouse model of osteoarthritis.
Journal Article Osteoarthritis Cartilage · March 2025 OBJECTIVE: We test whether the specialized pro-resolving molecule Maresin 1 (MaR1) attenuates nociceptive behaviors in mice with osteoarthritis-like pain. DESIGN: Osteoarthritis (OA)-like pain behavior was induced by intra-articular injection of monosodium ... Full text Link to item CiteRecent Grants
Localization of adenosine to promote fracture healing
ResearchSenior Research Associate · Awarded by National Institute on Aging · 2022 - 2027Modulation of local adenosine signaling to attenuate fracture pain
ResearchSenior Research Associate · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2021 - 2027Adenosine A2B Receptor in Bone Health and Osteoporosis
ResearchSenior Research Associate · Awarded by National Institutes of Health · 2017 - 2023View All Grants
Education, Training & Certifications
National Yang Ming University (Taiwan) ·
2010
Ph.D.