Overview
My research is focused on the study of molecular mechanisms of orthopaedic and neurological conditions using preclinical in vivo models, ex vivo systems, and behavioral analyses, and using these understandings for the development of novel therapeutics.
Current Appointments & Affiliations
Assistant Professor of Orthopaedic Surgery
·
2022 - Present
Orthopaedic Surgery,
Clinical Science Departments
Recent Publications
Enabling adenosine signaling to promote aged fracture healing.
Journal Article NPJ Regen Med · April 9, 2025 Bone fractures and related complications are a significant concern for older adults, particularly with the growing aging population. Therapeutic interventions that promote bone tissue regeneration are attractive for geriatric fracture repair. Extracellular ... Full text Link to item CiteSpecialized pro-resolving mediator Maresin 1 attenuates pain in a mouse model of osteoarthritis.
Journal Article Osteoarthritis Cartilage · March 2025 OBJECTIVE: We test whether the specialized pro-resolving molecule Maresin 1 (MaR1) attenuates nociceptive behaviors in mice with osteoarthritis-like pain. DESIGN: Osteoarthritis (OA)-like pain behavior was induced by intra-articular injection of monosodium ... Full text Link to item CiteMulti-Functional Small Molecule Alleviates Fracture Pain and Promotes Bone Healing.
Journal Article Adv Sci (Weinh) · December 2023 Bone injuries such as fractures are one major cause of morbidities worldwide. A considerable number of fractures suffer from delayed healing, and the unresolved acute pain may transition to chronic and maladaptive pain. Current management of pain involves ... Full text Open Access Link to item CiteRecent Grants
Localization of adenosine to promote fracture healing
ResearchSenior Research Associate · Awarded by National Institute on Aging · 2022 - 2027Understanding the role of senescence on post-operative neuroinflammation
ResearchSenior Research Associate · Awarded by National Institutes of Health · 2022 - 2026Modulation of local adenosine signaling to attenuate fracture pain
ResearchSenior Research Associate · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2021 - 2026View All Grants
Education, Training & Certifications
National Yang Ming University (Taiwan) ·
2010
Ph.D.