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Victoria Goldenshtein

Postdoctoral Associate
Biomedical Engineering

Overview


Trained as an analytical chemist, my undergraduate research involved investigating how zinc finger proteins interacted with heavy metals.  During my pursuit of a master's degree, I joined the Mathiowitz lab at Brown University, where I learned about polymeric nanoencapsulation techniques and explored the factors influencing the interaction of nanoparticles with gastrointestinal mucin, with the goal of creating innovative oral drug delivery systems.

My fascination with the DART method, specifically its ability to provide precise targeting at the cellular and molecular levels, drove my interest in the Tadross lab. I pursued my Ph.D. at Duke University, where, under the guidance of Professor Tadross, I developed a groundbreaking technology called GRIP Display. This technology enables the simultaneous screening of a vast number of protein variants (10^14) against a specific target, resulting in the rapid evolution of optimal variants, a process known as protein evolution.

As a current postdoctoral associate in the Tadross lab, I am focused on applying the GRIP technology to create biological therapeutics that can effectively penetrate solid tumors, particularly for diseases like Hepatocellular Carcinoma. My aim is to translate this technology into the biotech industry.

Educational Background
Doctor of Philosophy

Biomedical Engineering
Duke University (Durham, NC, USA) 2017-2023

Master of Science
Biomedical Engineering
Brown University (Providence, RI, USA) 2015-2017

Bachelors of Science
Chemistry, Biochemistry minor
CUNY (Brooklyn, NY, USA) 2007-2011

Current Appointments & Affiliations


In the News


Published August 25, 2023
NCBiotech Awards $2.75 Million in Grants, Loans in Latest Quarter
Published July 5, 2023
Advancing directed protein evolution technology
Published June 1, 2023
AWIS Graduate Spotlight

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Recent Grants


GRIP Display NCBioTech

ResearchGraduate Student · Awarded by North Carolina Biotechnology Center · 2023 - 2025

DART2.0: comprehensive cell type-specific behavioral neuropharmacology

ResearchGraduate Student · Awarded by National Institutes of Health · 2018 - 2022

View All Grants