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Vidyalakshmi Chandramohan

Associate Professor in Neurosurgery
Neurosurgery, Neuro-Oncology
Box 3156 Med Ctr, Durham, NC 27710
185 MSRB, Durham, NC 27710


The research work in my laboratory focuses on identifying novel immunotherapeutic targets for the treatment of brain tumors, specifically glioblastoma (GBM). My previous work includes the development of the dual-specific immunotoxin (IT) D2C7-IT, which is currently in Phase I clinical trials in recurrent GBM (rGBM) patients. My current research seeks to identify novel strategies to enhance the efficacy of D2C7-IT and other GBM-targeted cytotoxic therapies. In conjunction with this, my research includes the investigation of immune-related biomarkers to predict the clinical outcome of D2C7-IT therapy in patients with GBM.

Current Appointments & Affiliations

Associate Professor in Neurosurgery · 2021 - Present Neurosurgery, Neuro-Oncology, Neurosurgery
Associate Professor in Pathology · 2020 - Present Pathology, Clinical Science Departments
Member of the Duke Cancer Institute · 2015 - Present Duke Cancer Institute, Institutes and Centers

Education, Training & Certifications

North Carolina State University · 2020 M.B.A.
Boston University · 2006 Ph.D.