Overview
The research work in my laboratory focuses on identifying novel immunotherapeutic targets for the treatment of brain tumors, specifically glioblastoma (GBM). My previous work includes the development of the dual-specific immunotoxin (IT) D2C7-IT, which is currently in Phase I clinical trials in recurrent GBM (rGBM) patients. My current research seeks to identify novel strategies to enhance the efficacy of D2C7-IT and other GBM-targeted cytotoxic therapies. In conjunction with this, my research includes the investigation of immune-related biomarkers to predict the clinical outcome of D2C7-IT therapy in patients with GBM.
Current Appointments & Affiliations
Associate Professor in Neurosurgery
·
2021 - Present
Neurosurgery, Neuro-Oncology,
Neurosurgery
Associate Professor in Pathology
·
2020 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2015 - Present
Duke Cancer Institute,
Institutes and Centers
Education, Training & Certifications
North Carolina State University ·
2020
M.B.A.
Boston University ·
2006
Ph.D.