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Warwick Aubrey Ames

Professor of Anesthesiology
Anesthesiology, Pediatrics
Box 3094 Med Ctr, Durham, NC 27710
2905 Children's Health Center, Durham, NC 27710

Selected Publications


Analgesic Effects of a Novel Combination of Regional Anesthesia After Pediatric Cardiac Surgery: A Retrospective Cohort Study.

Journal Article J Cardiothorac Vasc Anesth · November 2022 OBJECTIVE: The objective of this study was to determine whether the use of regional anesthesia in children undergoing congenital heart surgery was associated with differences in outcomes when compared to surgeon-delivered local anesthetic wound infiltratio ... Full text Link to item Cite

An update on the management of PONV in a pediatric patient.

Journal Article Best Pract Res Clin Anaesthesiol · December 2020 Postoperative nausea and vomiting (PONV) is a major cause of patient dissatisfaction following anesthesia. The difficulty in diagnosing nausea in much of the pediatric population has led to an emphasis on anti-emetic prophylaxis for all. Assessment scores ... Full text Link to item Cite

Recycle: Do It for the Kids.

Journal Article J Cardiothorac Vasc Anesth · December 2020 Full text Link to item Cite

Big Syringe, Little Syringe.

Journal Article J Cardiothorac Vasc Anesth · September 2020 Full text Link to item Cite

The effect of intraoperative methadone during pediatric cardiac surgery on postoperative opioid requirements.

Journal Article Paediatr Anaesth · July 2020 BACKGROUND: Pain control in pediatric patients undergoing cardiac surgery presents a unique challenge. Postoperatively, many of these patients require long-term opioid infusions and sedation leading to need for prolonged weaning from opioids and longer hos ... Full text Link to item Cite

Postanesthesia Care Unit Management

Chapter · January 1, 2020 In infants, perioperative anesthetic morbidity is higher than in other age groups, which underscores the importance of the dedicated pediatric postanesthesia care unit (PACU). The pediatric PACU environment requires careful planning and ongoing maintenance ... Full text Cite

A Study of Practice Behavior for Endotracheal Intubation Site for Children With Congenital Heart Disease Undergoing Surgery: Impact of Endotracheal Intubation Site on Perioperative Outcomes-An Analysis of the Society of Thoracic Surgeons Congenital Cardiac Anesthesia Society Database.

Journal Article Anesth Analg · October 2019 BACKGROUND: In adults undergoing cardiopulmonary bypass surgery, oral intubation is typically preferred over nasal intubation due to reduced risk of sinusitis and infection. In children, nasal intubation is more common and sometimes preferred due to percei ... Full text Open Access Link to item Cite

Primum Non Nocere.

Journal Article J Cardiothorac Vasc Anesth · July 2019 Full text Link to item Cite

Double-Blind, Randomized, Placebo-Controlled Trial Comparing the Effects of Antithrombin Versus Placebo on the Coagulation System in Infants with Low Antithrombin Undergoing Congenital Cardiac Surgery.

Journal Article J Cardiothorac Vasc Anesth · February 2019 OBJECTIVES: To determine whether precardiopulmonary bypass (CPB) normalization of antithrombin levels in infants to 100% improves heparin sensitivity and anticoagulation during CPB and has beneficial effects into the postoperative period. DESIGN: Randomize ... Full text Link to item Cite

Essentials of Nephrology

Chapter · January 1, 2019 The basic functions of the kidney are to maintain fluid and electrolyte homeostasis and metabolism. Renal disease requires the practitioner to be vigilant about fluid homeostasis, acid-base balance, electrolyte management, choice of anesthetics, and potent ... Full text Cite

Essentials of Nephrology

Chapter · January 1, 2018 The basic functions of the kidney are to maintain fluid and electrolyte homeostasis and metabolism. Renal disease requires the practitioner to be vigilant about fluid homeostasis, acid-base balance, electrolyte management, choice of anesthetics, and potent ... Full text Cite

Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heart surgery.

Journal Article Paediatr Anaesth · March 2017 OBJECTIVE: Thrombocytopenia and acute kidney injury (AKI) are common following pediatric cardiac surgery with cardiopulmonary bypass (CPB). However, the relationship between postoperative nadir platelet counts and AKI has not been investigated in the pedia ... Full text Link to item Cite

Upper Extremity Peripheral Intravenous Line Infiltration With Concomitant Loss of Pulses Treated With Lipoaspiration: A Case Report.

Journal Article A A Case Rep · November 1, 2016 Peripheral intravenous cannulation in children is associated with occasional morbidity. We present a case where a large volume of blood, administered through a small peripheral cannula in the antecubital fossa, was found to have extravasated into the soft ... Full text Link to item Cite

Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.

Journal Article Perfusion · October 2016 BACKGROUND: Current trends in pediatric cardiac surgery and anesthesiology include goal-directed allogeneic blood transfusion, but few studies address the transfusion of platelets and cryoprecipitate. We report a quality improvement initiative to reduce th ... Full text Link to item Cite

Cardiopulmonary Bypass Strategy for a Cyanotic Child With Hemoglobin SC Disease.

Journal Article Ann Thorac Surg · June 2016 Hemoglobin SC (HbSC) disease is a hemoglobinopathy that may produce sickling under conditions of hypoxemia, dehydration, and acidosis. We present a case of HbSC disease and tricuspid atresia, type IB. We describe management by cardiopulmonary bypass CPB us ... Full text Link to item Cite

A change in anticoagulation monitoring improves safety, reduces transfusion, and reduces costs in infants on cardiopulmonary bypass.

Journal Article Paediatr Anaesth · June 2015 BACKGROUND: An immature coagulation system coupled with the hypothermia and hemodilution associated with cardiopulmonary bypass (CPB) in infants makes the activated clotting time (ACT) an ineffective monitor for anticoagulation in this population. The Medt ... Full text Link to item Cite