Lana L. Watkins | Scholars@Duke

Lana L. Watkins
Professor Emeritus in Psychiatry and Behavioral Sciences

* Examination of the relationship between affective disorders and autonomic cardiovascular control.

* Examination of the mechanisms underlying the increased cardiac mortality associated with anxiety disorders.

* Examination of the role of behavioral factors (diet, exercise) as modulators of glycemic control and in the pathogenesis of cardiovascular autonomic neuropathy.

Current Appointments & Affiliations

Professor Emeritus in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2023

Contact Information

3119 Hosp South, Durham, NC 27710
Box 3119 Med Ctr, Durham, NC 27710
watki017@mc.duke.edu (919) 681-4087

Background
Education, Training, & Certifications
- Ph.D., University of North Carolina - Chapel Hill 1991
- B.S., University of Florida 1984
Previous Appointments & Affiliations
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2021 - 2023
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2019 - 2020
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2013 - 2019
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2006 - 2013
- Associate Research Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2004 - 2006
- Assistant Research Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1997 - 2004
- Instructor, Temporary in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1997
Research
Selected Grants
- The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk awarded by National Institutes of Health 2016 - 2023
- Neuromodulatory Treatments for Pain Management in Complex TBI using Mobile Technology awarded by Department of Defense 2017 - 2022
- Exercise and Pharmacotherapy for Anxiety in Cardiac Patients awarded by National Institutes of Health 2015 - 2022
- Facility and Web-based Approaches to Lifestyle Change in Resistant Hypertension awarded by National Institutes of Health 2014 - 2021
- Depression and Heart Failure Disease Progression awarded by National Institutes of Health 2014 - 2019
- Stress Management and Biomarkers of Risk in Cardiac Rehabilitation awarded by National Institutes of Health 2009 - 2016
- Hostility, PTSD and Physical Health Risk Factors awarded by National Institutes of Health 2009 - 2015
- Depression, Estrogen Replacement, and Cardiovascular Health in the Perimenopause awarded by University of North Carolina - Chapel Hill 2010 - 2015
- Ancillary Investigation of Mental Stress Biomarkers in Coronary Heart Disease awarded by National Institutes of Health 2010 - 2015
- Coping Skills Training in Heart Failure: Outcomes and Mechanisms awarded by National Institutes of Health 2009 - 2015
- IPA - Lana Watkins awarded by Durham Veterans Affairs Medical Center 2013 - 2014
- IPA - Monika Grochulski awarded by Durham Veterans Affairs Medical Center 2013 - 2014
- Exercise, Depression, and Cardiac Risk awarded by National Institutes of Health 2006 - 2012
- Behavioral Treatment of High Blood Pressure awarded by National Institutes of Health 2003 - 2010
- Depression and Autonomic Control in Post-MI Patients awarded by National Institutes of Health 2003 - 2009
- Exercise Training And Depression In Older Adults awarded by National Institutes of Health 1998 - 2007
- Stress & Myocardial Ischemia: Mechanisms & Treatment awarded by National Institutes of Health 1998 - 2006
- Stress & Congestive Heart Failure:Prognosis & Mechanisms awarded by National Institutes of Health 1999 - 2005
- Anxiety & Vagal Control of the Heart in Coronary Disease awarded by National Institutes of Health 1999 - 2005
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Watkins, Lana L., Stefanie T. LoSavio, Patrick Calhoun, Patricia A. Resick, Andrew Sherwood, Cynthia J. Coffman, Angela C. Kirby, Tiffany A. Beaver, Michelle F. Dennis, and Jean C. Beckham. “Effect of cognitive processing therapy on markers of cardiovascular risk in posttraumatic stress disorder patients: A randomized clinical trial.” J Psychosom Res 170 (May 2, 2023): 111351. https://doi.org/10.1016/j.jpsychores.2023.111351.
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  - Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial.” J Cardiovasc Dev Dis 9, no. 10 (September 22, 2022). https://doi.org/10.3390/jcdd9100320.
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  - Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, et al. “Longer term benefits of exercise and escitalopram in the treatment of anxiety in patients with coronary heart disease: Six month follow-up of the UNWIND randomized clinical trial.” Am Heart J 251 (September 2022): 91–100. https://doi.org/10.1016/j.ahj.2022.05.014.
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  - Smith, Patrick J., Andrew Sherwood, Alan L. Hinderliter, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.” J Hypertens 40, no. 7 (July 1, 2022): 1359–68. https://doi.org/10.1097/HJH.0000000000003151.
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  - Van Voorhees, Elizabeth E., Paul A. Dennis, Lana L. Watkins, Tapan A. Patel, Patrick S. Calhoun, Michelle F. Dennis, and Jean C. Beckham. “Ambulatory Heart Rate Variability Monitoring: Comparisons Between the Empatica E4 Wristband and Holter Electrocardiogram.” Psychosom Med 84, no. 2 (February 2022): 210–14. https://doi.org/10.1097/PSY.0000000000001010.
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  - Smith, Patrick J., Andrew Sherwood, Alan L. Hinderliter, Stephanie Mabe, Crystal Tyson, Forgive Avorgbedor, Lana L. Watkins, Pao-Hwa Lin, William E. Kraus, and James A. Blumenthal. “Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.” J Alzheimers Dis 87, no. 1 (2022): 345–57. https://doi.org/10.3233/JAD-215522.
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  - Blumenthal, James A., Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, Lawrence Liao, Jonathan Davidson, and Andrew Sherwood. “Effect of Exercise, Escitalopram, or Placebo on Anxiety in Patients With Coronary Heart Disease: The Understanding the Benefits of Exercise and Escitalopram in Anxious Patients With Coronary Heart Disease (UNWIND) Randomized Clinical Trial.” Jama Psychiatry 78, no. 11 (November 1, 2021): 1270–78. https://doi.org/10.1001/jamapsychiatry.2021.2236.
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  - Blumenthal, James A., Alan L. Hinderliter, Patrick J. Smith, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.” Circulation 144, no. 15 (October 12, 2021): 1212–26. https://doi.org/10.1161/CIRCULATIONAHA.121.055329.
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  - Andersen, Elizabeth, Paul Geiger, Crystal Schiller, Karen Bluth, Lana Watkins, Ying Zhang, Kai Xia, et al. “Effects of Mindfulness-Based Stress Reduction on Experimental Pain Sensitivity and Cortisol Responses in Women With Early Life Abuse: A Randomized Controlled Trial.” Psychosom Med 83, no. 6 (July 2021): 515–27. https://doi.org/10.1097/PSY.0000000000000889.
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  - LoSavio, Stefanie T., Jean C. Beckham, Stephanie Y. Wells, Patricia A. Resick, Andrew Sherwood, Cynthia J. Coffman, Angela C. Kirby, Tiffany A. Beaver, Michelle F. Dennis, and Lana L. Watkins. “The effect of reducing posttraumatic stress disorder symptoms on cardiovascular risk: Design and methodology of a randomized clinical trial.” Contemp Clin Trials 102 (March 2021): 106269. https://doi.org/10.1016/j.cct.2021.106269.
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  - Yano, Yuichiro, Anthony J. Viera, Alan L. Hinderliter, Lana L. Watkins, James A. Blumenthal, Kristy S. Johnson, LaBarron K. Hill, and Andrew Sherwood. “Vascular α1-Adrenergic Receptor Responsiveness in Masked Hypertension.” Am J Hypertens 33, no. 8 (August 4, 2020): 713–17. https://doi.org/10.1093/ajh/hpaa032.
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  - Gordon, Jennifer L., David R. Rubinow, Lana Watkins, Alan L. Hinderliter, Melissa C. Caughey, and Susan S. Girdler. “The Effect of Perimenopausal Transdermal Estradiol and Micronized Progesterone on Markers of Risk for Arterial Disease.” J Clin Endocrinol Metab 105, no. 5 (May 1, 2020): e2050–60. https://doi.org/10.1210/clinem/dgz262.
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  - Dennis, Paul A., Julia M. Neal, Emili Travis, Lana L. Watkins, Patrick S. Calhoun, Michelle F. Dennis, and Jean C. Beckham. “Negative Affect-Related Autonomic Arousal Mediates the Association between Baroreflex Dysfunction and Insulin Resistance in Non-Diabetic Young Adults.” J Psychophysiol 33, no. 4 (October 2019): 243–53. https://doi.org/10.1027/0269-8803/a000226.
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  - Blumenthal, James A., Yidan Zhu, Gary G. Koch, Patrick J. Smith, Lana L. Watkins, Alan L. Hinderliter, Benson M. Hoffman, et al. “The modifying effects of social support on psychological outcomes in patients with heart failure.” Health Psychol 38, no. 6 (June 2019): 502–8. https://doi.org/10.1037/hea0000716.
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  - Blakey, S. M., A. C. Kirby, K. E. McClure, E. B. Elbogen, J. C. Beckham, L. L. Watkins, and J. D. Clapp. “Posttraumatic Safety Behaviors: Characteristics and Associations With Symptom Severity in Two Samples.” Traumatology, January 1, 2019. https://doi.org/10.1037/trm0000205.
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  - Smith, Patrick J., James A. Blumenthal, Alan L. Hinderliter, Lana L. Watkins, Benson M. Hoffman, and Andrew Sherwood. “Microvascular Endothelial Function and Neurocognition Among Adults With Major Depressive Disorder.” Am J Geriatr Psychiatry 26, no. 10 (October 2018): 1061–69. https://doi.org/10.1016/j.jagp.2018.06.011.
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  - Smith, Patrick J., Andrew Sherwood, Stephanie Mabe, Lana Watkins, Alan Hinderliter, and James A. Blumenthal. “Physical activity and psychosocial function following cardiac rehabilitation: One-year follow-up of the ENHANCED study.” Gen Hosp Psychiatry 49 (November 2017): 32–36. https://doi.org/10.1016/j.genhosppsych.2017.05.001.
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  - Hill, LaBarron K., Lana L. Watkins, Alan L. Hinderliter, James A. Blumenthal, and Andrew Sherwood. “Racial differences in the association between heart rate variability and left ventricular mass.” Exp Physiol 102, no. 7 (July 1, 2017): 764–72. https://doi.org/10.1113/EP086228.
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  - Sherwood, Andrew, James A. Blumenthal, Gary G. Koch, Benson M. Hoffman, Lana L. Watkins, Patrick J. Smith, Christopher M. O’Connor, et al. “Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003410.
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  - Dennis, Paul A., Nathan A. Kimbrel, Andrew Sherwood, Patrick S. Calhoun, Lana L. Watkins, Michelle F. Dennis, and Jean C. Beckham. “Trauma and Autonomic Dysregulation: Episodic - Versus Systemic - Negative Affect Underlying Cardiovascular Risk in Posttraumatic Stress Disorder.” Psychosom Med, December 9, 2016. https://doi.org/10.1097/PSY.0000000000000438.
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  - Rissling, Michelle B., Paul A. Dennis, Lana L. Watkins, Patrick S. Calhoun, Michelle F. Dennis, Jean C. Beckham, Junichiro Hayano, and Christi S. Ulmer. “Circadian Contrasts in Heart Rate Variability Associated With Posttraumatic Stress Disorder Symptoms in a Young Adult Cohort.” J Trauma Stress 29, no. 5 (October 2016): 415–21. https://doi.org/10.1002/jts.22125.
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  - Dennis, Paul A., Eric A. Dedert, Elizabeth E. Van Voorhees, Lana L. Watkins, Junichiro Hayano, Patrick S. Calhoun, Andrew Sherwood, Michelle F. Dennis, and Jean C. Beckham. “Examining the Crux of Autonomic Dysfunction in Posttraumatic Stress Disorder: Whether Chronic or Situational Distress Underlies Elevated Heart Rate and Attenuated Heart Rate Variability.” Psychosom Med 78, no. 7 (September 2016): 805–9. https://doi.org/10.1097/PSY.0000000000000326.
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  - Blumenthal, James A., Bryan J. Feger, Patrick J. Smith, Lana L. Watkins, Wei Jiang, Jonathan Davidson, Benson M. Hoffman, et al. “Treatment of anxiety in patients with coronary heart disease: Rationale and design of the UNderstanding the benefits of exercise and escitalopram in anxious patients WIth coroNary heart Disease (UNWIND) randomized clinical trial.” Am Heart J 176 (June 2016): 53–62. https://doi.org/10.1016/j.ahj.2016.03.003.
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  - Sherwood, Andrew, James A. Blumenthal, Patrick J. Smith, Lana L. Watkins, Benson M. Hoffman, and Alan L. Hinderliter. “Effects of Exercise and Sertraline on Measures of Coronary Heart Disease Risk in Patients With Major Depression: Results From the SMILE-II Randomized Clinical Trial.” Psychosom Med 78, no. 5 (June 2016): 602–9. https://doi.org/10.1097/PSY.0000000000000301.
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  - Blumenthal, James A., Andrew Sherwood, Patrick J. Smith, Lana Watkins, Stephanie Mabe, William E. Kraus, Krista Ingle, Paula Miller, and Alan Hinderliter. “Enhancing Cardiac Rehabilitation With Stress Management Training: A Randomized, Clinical Efficacy Trial.” Circulation 133, no. 14 (April 5, 2016): 1341–50. https://doi.org/10.1161/CIRCULATIONAHA.115.018926.
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  - Dennis, Paul A., J Brice Weinberg, Patrick S. Calhoun, Lana L. Watkins, Andrew Sherwood, Michelle F. Dennis, and Jean C. Beckham. “An investigation of vago-regulatory and health-behavior accounts for increased inflammation in posttraumatic stress disorder.” J Psychosom Res 83 (April 2016): 33–39. https://doi.org/10.1016/j.jpsychores.2016.02.008.
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  - Green, Kimberly T., Paul A. Dennis, Lydia C. Neal, Andrea L. Hobkirk, Terrell A. Hicks, Lana L. Watkins, Junichiro Hayano, Andrew Sherwood, Patrick S. Calhoun, and Jean C. Beckham. “Exploring the relationship between posttraumatic stress disorder symptoms and momentary heart rate variability.” J Psychosom Res 82 (March 2016): 31–34. https://doi.org/10.1016/j.jpsychores.2016.01.003.
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  - Blumenthal, James A., Andrew Sherwood, Patrick J. Smith, Stephanie Mabe, Lana Watkins, Pao-Hwa Lin, Linda W. Craighead, et al. “Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.” Am Heart J 170, no. 5 (November 2015): 986-994.e5. https://doi.org/10.1016/j.ahj.2015.08.006.
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  - Singh, Abanish, Michael A. Babyak, Beverly H. Brummett, Rong Jiang, Lana L. Watkins, John C. Barefoot, William E. Kraus, et al. “Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene.” Genet Epidemiol 39, no. 6 (September 2015): 489–97. https://doi.org/10.1002/gepi.21910.
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  - Oddone, Ania E., Paul A. Dennis, Patrick S. Calhoun, Lana L. Watkins, Andrew Sherwood, Eric A. Dedert, Kimberly T. Green, Jacob N. Stein, Michelle F. Dennis, and Jean C. Beckham. “Orthostatic hypotension in young adults with and without posttraumatic stress disorder.” Psychol Trauma 7, no. 3 (May 2015): 229–33. https://doi.org/10.1037/a0036716.
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  - Fan, L. -. B., J. A. Blumenthal, L. L. Watkins, and A. Sherwood. “Work and home stress: associations with anxiety and depression symptoms.” Occup Med (Lond) 65, no. 2 (March 2015): 110–16. https://doi.org/10.1093/occmed/kqu181.
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  - Paine, Nicola J., Lana L. Watkins, James A. Blumenthal, Cynthia M. Kuhn, and Andrew Sherwood. “Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.” Psychosom Med 77, no. 2 (2015): 136–44. https://doi.org/10.1097/PSY.0000000000000144.
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  - Dennis, Paul A., Lana L. Watkins, Patrick S. Calhoun, Ania Oddone, Andrew Sherwood, Michelle F. Dennis, Michelle B. Rissling, and Jean C. Beckham. “Posttraumatic stress, heart rate variability, and the mediating role of behavioral health risks.” Psychosom Med 76, no. 8 (October 2014): 629–37. https://doi.org/10.1097/PSY.0000000000000110.
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  - Dennis, Paul A., Christi S. Ulmer, Patrick S. Calhoun, Andrew Sherwood, Lana L. Watkins, Michelle F. Dennis, and Jean C. Beckham. “Behavioral health mediators of the link between posttraumatic stress disorder and dyslipidemia.” J Psychosom Res 77, no. 1 (July 2014): 45–50. https://doi.org/10.1016/j.jpsychores.2014.05.001.
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  - Hinderliter, Alan L., Andrew Sherwood, Linda W. Craighead, Pwa-Hwa Lin, Lana Watkins, Michael A. Babyak, and James A. Blumenthal. “The long-term effects of lifestyle change on blood pressure: One-year follow-up of the ENCORE study.” Am J Hypertens 27, no. 5 (May 2014): 734–41. https://doi.org/10.1093/ajh/hpt183.
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  - Haynes, R., C. Baigent, P. Harden, M. Landray, M. Akyol, A. Asderakis, A. Baxter, et al. “Campath, calcineurin inhibitor reduction and chronic allograft nephropathy (3C) study: Background, rationale, and study protocol.” Transplantation Research 2, no. 1 (May 6, 2013). https://doi.org/10.1186/2047-1440-2-7.
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  - Watkins, Lana L., Gary G. Koch, Andrew Sherwood, James A. Blumenthal, Jonathan R. T. Davidson, Christopher O’Connor, and Michael H. Sketch. “Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.” J Am Heart Assoc 2, no. 2 (March 19, 2013): e000068. https://doi.org/10.1161/JAHA.112.000068.
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  - Kisohara, Masaya, Phyllis K. Stein, Yutaka Yoshida, Mari Suzuki, Narushi Iizuka, Robert M. Carney, Lana L. Watkins, Kenneth E. Freedland, James A. Blumenthal, and Junichiro Hayano. “Multi-scale heart rate dynamics detected by phase-rectified signal averaging predicts mortality after acute myocardial infarction.” Europace 15, no. 3 (March 2013): 437–43. https://doi.org/10.1093/europace/eus409.
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  - Blumenthal, J. A., A. Sherwood, L. L. Watkins, and A. Hinderliter. “Reply.” Journal of the American College of Cardiology 60, no. 23 (December 11, 2012): 2425–26. https://doi.org/10.1016/j.jacc.2012.09.009.
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  - Hayano, Junichiro, Robert M. Carney, Eiichi Watanabe, Kiyohiro Kawai, Itsuo Kodama, Phyllis K. Stein, Lana L. Watkins, Kenneth E. Freedland, and James A. Blumenthal. “Interactive associations of depression and sleep apnea with adverse clinical outcomes after acute myocardial infarction.” Psychosom Med 74, no. 8 (October 2012): 832–39. https://doi.org/10.1097/PSY.0b013e31826d2c81.
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  - Blumenthal, James A., Andrew Sherwood, Michael A. Babyak, Lana L. Watkins, Patrick J. Smith, Benson M. Hoffman, C Virginia F. O’Hayer, et al. “Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study.” J Am Coll Cardiol 60, no. 12 (September 18, 2012): 1053–63. https://doi.org/10.1016/j.jacc.2012.04.040.
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  - Sherwood, Andrew, Christopher M. O’Connor, Faye S. Routledge, Alan L. Hinderliter, Lana L. Watkins, Michael A. Babyak, Gary G. Koch, et al. “Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.” J Card Fail 17, no. 3 (March 2011): 201–7. https://doi.org/10.1016/j.cardfail.2010.11.001.
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  - Hayano, Junichiro, Ken Kiyono, Zbigniew R. Struzik, Yoshiharu Yamamoto, Eiichi Watanabe, Phyllis K. Stein, Lana L. Watkins, James A. Blumenthal, and Robert M. Carney. “Increased non-gaussianity of heart rate variability predicts cardiac mortality after an acute myocardial infarction.” Front Physiol 2 (2011): 65. https://doi.org/10.3389/fphys.2011.00065.
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  - Sharp Collaborative Group, Carlos L. “Study of Heart and Renal Protection (SHARP): randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease.” Am Heart J 160, no. 5 (November 2010): 785-794.e10. https://doi.org/10.1016/j.ahj.2010.08.012.
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  - Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, Lana L. Watkins, Alan Hinderliter, Benson M. Hoffman, David C. Steffens, Andrew Sherwood, and P Murali Doraiswamy. “Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression.” Am J Geriatr Psychiatry 18, no. 9 (September 2010): 848–52. https://doi.org/10.1097/JGP.0b013e3181dba0fa.
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  - Watkins, Lana L., James A. Blumenthal, Michael A. Babyak, Jonathan R. T. Davidson, Charles B. McCants, Christopher O’Connor, and Michael H. Sketch. “Phobic anxiety and increased risk of mortality in coronary heart disease.” Psychosom Med 72, no. 7 (September 2010): 664–71. https://doi.org/10.1097/PSY.0b013e3181e9f357.
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  - Blumenthal, James A., Michael A. Babyak, Andrew Sherwood, Linda Craighead, Pao-Hwa Lin, Julie Johnson, Lana L. Watkins, et al. “Effects of the dietary approaches to stop hypertension diet alone and in combination with exercise and caloric restriction on insulin sensitivity and lipids.” Hypertension 55, no. 5 (May 2010): 1199–1205. https://doi.org/10.1161/HYPERTENSIONAHA.109.149153.
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  - Dedert, Eric A., Patrick S. Calhoun, Lana L. Watkins, Andrew Sherwood, and Jean C. Beckham. “Posttraumatic stress disorder, cardiovascular, and metabolic disease: a review of the evidence.” Ann Behav Med 39, no. 1 (February 2010): 61–78. https://doi.org/10.1007/s12160-010-9165-9.
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  - Blumenthal, James A., Michael A. Babyak, Alan Hinderliter, Lana L. Watkins, Linda Craighead, Pao-Hwa Lin, Carla Caccia, Julie Johnson, Robert Waugh, and Andrew Sherwood. “Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study.” Arch Intern Med 170, no. 2 (January 25, 2010): 126–35. https://doi.org/10.1001/archinternmed.2009.470.
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  - Blumenthal, James A., Jenny T. Wang, Michael Babyak, Lana Watkins, William Kraus, Paula Miller, Alan Hinderliter, and Andrew Sherwood. “Enhancing standard cardiac rehabilitation with stress management training: background, methods, and design for the enhanced study.” J Cardiopulm Rehabil Prev 30, no. 2 (2010): 77–84. https://doi.org/10.1097/HCR.0b013e3181d0c1d3.
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  - Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, Anastasia Georgiades, Andrew Sherwood, Michael H. Sketch, and Lana L. Watkins. “Association between n-3 fatty acid consumption and ventricular ectopy after myocardial infarction.” Am J Clin Nutr 89, no. 5 (May 2009): 1315–20. https://doi.org/10.3945/ajcn.2008.26829.
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  - Blumenthal, James A., Silvina Waldman, Michael A. Babyak, Andrew Sherwood, Michael Sketch, and Lana L. Watkins. “TREATING DEPRESSION IN PATIENTS WITH HEART DISEASE: Is the Glass Half Empty or Half Full?” Am Heart J 157, no. 5 (May 1, 2009): e35–37. https://doi.org/10.1016/j.ahj.2009.03.006.
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  - Waldman, Silvina V., James A. Blumenthal, Michael A. Babyak, Andrew Sherwood, Michael Sketch, Jonathan Davidson, and Lana L. Watkins. “Ethnic differences in the treatment of depression in patients with ischemic heart disease.” Am Heart J 157, no. 1 (January 2009): 77–83. https://doi.org/10.1016/j.ahj.2008.08.013.
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  - Carney, Robert M., Brian Steinmeyer, Kenneth E. Freedland, James A. Blumenthal, Phyllis K. Stein, William A. Steinhoff, William B. Howells, et al. “Nighttime heart rate and survival in depressed patients post acute myocardial infarction.” Psychosom Med 70, no. 7 (September 2008): 757–63. https://doi.org/10.1097/PSY.0b013e3181835ca3.
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  - Carney, Robert M., Kenneth E. Freedland, Brian Steinmeyer, James A. Blumenthal, Lisa F. Berkman, Lana L. Watkins, Susan M. Czajkowski, Matthew M. Burg, and Allan S. Jaffe. “Depression and five year survival following acute myocardial infarction: a prospective study.” J Affect Disord 109, no. 1–2 (July 2008): 133–38. https://doi.org/10.1016/j.jad.2007.12.005.
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  - Carney, Robert M., William B. Howells, James A. Blumenthal, Kenneth E. Freedland, Phyllis K. Stein, Lisa F. Berkman, Lana L. Watkins, et al. “Heart rate turbulence, depression, and survival after acute myocardial infarction.” Psychosom Med 69, no. 1 (January 2007): 4–9. https://doi.org/10.1097/01.psy.0000249733.33811.00.
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  - Smith, Patrick J., James A. Blumenthal, Michael A. Babyak, Anastasia Georgiades, Andrew Sherwood, Michael H. Sketch, and Lana L. Watkins. “Ventricular ectopy: impact of self-reported stress after myocardial infarction.” Am Heart J 153, no. 1 (January 2007): 133–39. https://doi.org/10.1016/j.ahj.2006.10.016.
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  - Blumenthal, James A., Andrew Sherwood, Sharon D. Rogers, Michael A. Babyak, P Murali Doraiswamy, Lana Watkins, Benson M. Hoffman, et al. “Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues.” Clin Trials 4, no. 5 (2007): 548–59. https://doi.org/10.1177/1740774507083388.
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  - Blumenthal, James A., Michael A. Babyak, P Murali Doraiswamy, Lana Watkins, Benson M. Hoffman, Krista A. Barbour, Steve Herman, et al. “Exercise and pharmacotherapy in the treatment of major depressive disorder.” Psychosom Med 69, no. 7 (2007): 587–96. https://doi.org/10.1097/PSY.0b013e318148c19a.
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  - Watkins, Lana L., James A. Blumenthal, Jonathan R. T. Davidson, Michael A. Babyak, Charles B. McCants, and Michael H. Sketch. “Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease.” Psychosom Med 68, no. 5 (2006): 651–56. https://doi.org/10.1097/01.psy.0000228342.53606.b3.
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  - Davidson, Jonathan, Lana Watkins, Michael Owens, Stan Krulewicz, Kathryn Connor, David Carpenter, Ranga Krishnan, and Charles Nemeroff. “Effects of paroxetine and venlafaxine XR on heart rate variability in depression.” J Clin Psychopharmacol 25, no. 5 (October 2005): 480–84. https://doi.org/10.1097/01.jcp.0000177547.28961.03.
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  - Sherwood, Andrew, Alan L. Hinderliter, Lana L. Watkins, Robert A. Waugh, and James A. Blumenthal. “Impaired endothelial function in coronary heart disease patients with depressive symptomatology.” J Am Coll Cardiol 46, no. 4 (August 16, 2005): 656–59. https://doi.org/10.1016/j.jacc.2005.05.041.
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  - Carney, Robert M., James A. Blumenthal, Kenneth E. Freedland, Phyllis K. Stein, William B. Howells, Lisa F. Berkman, Lana L. Watkins, et al. “Low heart rate variability and the effect of depression on post-myocardial infarction mortality.” Arch Intern Med 165, no. 13 (July 11, 2005): 1486–91. https://doi.org/10.1001/archinte.165.13.1486.
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  - Blumenthal, James A., Andrew Sherwood, Michael A. Babyak, Lana L. Watkins, Robert Waugh, Anastasia Georgiades, Simon L. Bacon, Junichiro Hayano, R Edward Coleman, and Alan Hinderliter. “Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial.” Jama 293, no. 13 (April 6, 2005): 1626–34. https://doi.org/10.1001/jama.293.13.1626.
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  - Hughes, Joel W., Alisha Tomlinson, James A. Blumenthal, Jonathan Davidson, Michael H. Sketch, and Lana L. Watkins. “Social support and religiosity as coping strategies for anxiety in hospitalized cardiac patients.” Ann Behav Med 28, no. 3 (December 2004): 179–85. https://doi.org/10.1207/s15324796abm2803_6.
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  - Hughes, Joel W., Lana Watkins, James A. Blumenthal, Cynthia Kuhn, and Andrew Sherwood. “Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women.” J Psychosom Res 57, no. 4 (October 2004): 353–58. https://doi.org/10.1016/j.jpsychores.2004.02.016.
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  - Bacon, Simon L., Lana L. Watkins, Michael Babyak, Andrew Sherwood, Junichiro Hayano, Alan L. Hinderliter, Robert Waugh, and James A. Blumenthal. “Effects of daily stress on autonomic cardiac control in patients with coronary artery disease.” Am J Cardiol 93, no. 10 (May 15, 2004): 1292–94. https://doi.org/10.1016/j.amjcard.2004.02.018.
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  - Carney, Robert M., James A. Blumenthal, Diane Catellier, Kenneth E. Freedland, Lisa F. Berkman, Lana L. Watkins, Susan M. Czajkowski, Junichiro Hayano, and Allan S. Jaffe. “Depression as a risk factor for mortality after acute myocardial infarction.” Am J Cardiol 92, no. 11 (December 1, 2003): 1277–81. https://doi.org/10.1016/j.amjcard.2003.08.007.
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  - Watkins, Lana L., Andrew Sherwood, Mark Feinglos, Alan Hinderliter, Michael Babyak, Elizabeth Gullette, Robert Waugh, and James A. Blumenthal. “Effects of exercise and weight loss on cardiac risk factors associated with syndrome X.” Arch Intern Med 163, no. 16 (September 8, 2003): 1889–95. https://doi.org/10.1001/archinte.163.16.1889.
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  - Watkins, Lana L., Neil Schneiderman, James A. Blumenthal, David S. Sheps, Diane Catellier, C Barr Taylor, Kenneth E. Freedland, and Kenneth E. ENRICHD Investigators. “Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarction.” Am Heart J 146, no. 1 (July 2003): 48–54. https://doi.org/10.1016/S0002-8703(03)00083-8.
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  - Berkman, L. F., J. Blumenthal, M. Burg, S. M. Czajkowski, and L. Watkins. “Treating depression and low perceived social support after myocardial infarction does not increase event-free survival.” Evidence Based Cardiovascular Medicine 7, no. 4 (January 1, 2003): 199–200. https://doi.org/10.1016/j.ebcm.2003.08.004.
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  - Carney, Robert M., Kenneth E. Freedland, Phyllis K. Stein, Lana L. Watkins, Diane Catellier, Allan S. Jaffe, and Vikram K. Yeragani. “Effects of depression on QT interval variability after myocardial infarction.” Psychosom Med 65, no. 2 (2003): 177–80. https://doi.org/10.1097/01.psy.0000033129.21715.4b.
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  - Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Revista De Psiquiatria Clinica 29, no. 3 (September 14, 2002): 158–59.
  - Watkins, Lana L., James A. Blumenthal, and Robert M. Carney. “Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction.” Am Heart J 143, no. 3 (March 2002): 460–66. https://doi.org/10.1067/mhj.2002.120404.
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  - Watkins, L. L., K. M. Connor, and J. R. Davidson. “Effect of kava extract on vagal cardiac control in generalized anxiety disorder: preliminary findings.” J Psychopharmacol 15, no. 4 (December 2001): 283–86. https://doi.org/10.1177/026988110101500407.
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  - Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Circulation 104, no. 17 (October 23, 2001): 2024–28. https://doi.org/10.1161/hc4201.097834.
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  - ENRICHD Investigators, D. W. “Enhancing recovery in coronary heart disease (ENRICHD): baseline characteristics.” Am J Cardiol 88, no. 3 (August 1, 2001): 316–22. https://doi.org/10.1016/s0002-9149(01)01652-6.
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  - Blumenthal, J. A., A. Hart, A. Sherwood, M. Doraiswamy, S. Herman, L. Watkins, A. Hinderliter, E. Gullette, and K. R. Krishnan. “Depression and vascular function in older adults. Evaluating the benefits of exercise in a new study at Duke University.” N C Med J 62, no. 2 (2001): 95–98.
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  - ENRICHD Investigators, G. “Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design.” Psychosom Med 63, no. 5 (2001): 747–55.
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  - Watkins, L. L., R. S. Surwit, and A. Sherwood. “Glycemic control and impaired autonomic function: Is glucose the sole culprit? [11].” Diabetes Care 23, no. 12 (December 12, 2000): 1863–64.
  - Watkins, L. L., R. S. Surwit, P. Grossman, and A. Sherwood. “Is there a glycemic threshold for impaired autonomic control?” Diabetes Care 23, no. 6 (June 2000): 826–30. https://doi.org/10.2337/diacare.23.6.826.
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  - Carney, R. M., K. E. Freedland, and P. K. Stein. “Anxiety, depression, and heart rate variability.” Psychosom Med 62, no. 1 (2000): 84–87. https://doi.org/10.1097/00006842-200001000-00013.
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  - Watkins, L. L., J. A. Blumenthal, P. R. Kowey, H. Z. Brandspiegel, R. A. Marinchak, and S. J. Rials. “Worried to death? [4] (multiple letters).” Circulation 100, no. 11 (September 14, 1999): 1251–52.
  - Watkins, L. L., and P. Grossman. “Association of depressive symptoms with reduced baroreflex cardiac control in coronary artery disease.” Am Heart J 137, no. 3 (March 1999): 453–57. https://doi.org/10.1016/s0002-8703(99)70491-6.
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  - Watkins, L. L., P. Grossman, R. Krishnan, and J. A. Blumenthal. “Anxiety reduces baroreflex cardiac control in older adults with major depression.” Psychosom Med 61, no. 3 (1999): 334–40. https://doi.org/10.1097/00006842-199905000-00012.
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  - Watkins, L. L., P. Grossman, R. Krishnan, and A. Sherwood. “Anxiety and vagal control of heart rate.” Psychosom Med 60, no. 4 (1998): 498–502. https://doi.org/10.1097/00006842-199807000-00018.
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  - Grossman, P., L. L. Watkins, H. Ristuccia, and F. H. Wilhelm. “Blood pressure responses to mental stress in emotionally defensive patients with stable coronary artery disease.” Am J Cardiol 80, no. 3 (August 1, 1997): 343–46. https://doi.org/10.1016/s0002-9149(97)00359-7.
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  - Ristuccia, H. L., P. Grossman, L. L. Watkins, and B. Lown. “Incremental bias in Finapres estimation of baseline blood pressure levels over time.” Hypertension 29, no. 4 (April 1997): 1039–43. https://doi.org/10.1161/01.hyp.29.4.1039.
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  - Grossman, P., L. L. Watkins, F. H. Wilhelm, D. Manolakis, and B. Lown. “Cardiac vagal control and dynamic responses to psychological stress among patients with coronary artery disease.” Am J Cardiol 78, no. 12 (December 15, 1996): 1424–27. https://doi.org/10.1016/s0002-9149(97)89295-8.
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  - Watkins, L. L., P. Grossman, and A. Sherwood. “Noninvasive assessment of baroreflex control in borderline hypertension. Comparison with the phenylephrine method.” Hypertension 28, no. 2 (August 1996): 238–43. https://doi.org/10.1161/01.hyp.28.2.238.
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  - Ziegler, M. G., R. A. Nelesen, P. J. Mills, S. Ancoli-Israel, J. L. Clausen, L. Watkins, and J. E. Dimsdale. “The effect of hypoxia on baroreflexes and pressor sensitivity in sleep apnea and hypertension.” Sleep 18, no. 10 (December 1995): 859–65.
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  - Watkins, L. L., C. Fainman, J. Dimsdale, and M. G. Ziegler. “Assessment of baroreflex control from beat-to-beat blood pressure and heart rate changes: a validation study.” Psychophysiology 32, no. 4 (July 1995): 411–14. https://doi.org/10.1111/j.1469-8986.1995.tb01224.x.
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  - Watkins, L. L., J. E. Dimsdale, and M. G. Ziegler. “Reduced beta 2-receptor mediated vasodilation in African Americans.” Life Sci 57, no. 15 (1995): 1411–16. https://doi.org/10.1016/0024-3205(95)02103-p.
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  - Ona, E., J. E. Dimsdale, S. Ancoli-Israel, E. Dillon, L. Watkins, T. V. Coy, and J. Clausen. “A technique for improved blood sampling during sleep studies.” Psychophysiology 31, no. 6 (November 1994): 609–10. https://doi.org/10.1111/j.1469-8986.1994.tb02353.x.
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  - Watkins, L., A. Sherwood, D. S. Goldstein, and W. Maixner. “Mechanisms underlying cardiovascular defense reaction evoked by dorsal periaqueductal gray stimulation.” Am J Physiol 265, no. 5 Pt 2 (November 1993): R1155–61. https://doi.org/10.1152/ajpregu.1993.265.5.R1155.
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  - Watkins, L., and W. Maixner. “Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats.” J Cardiovasc Pharmacol 21, no. 2 (February 1993): 264–71. https://doi.org/10.1097/00005344-199302000-00012.
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  - Watkins, L., A. Sherwood, D. S. Goldstein, and W. Maixner. “Mechanisms underlying cardiovascular defense reaction evoked by dorsal periaqueductal gray stimulation.” American Journal of Physiology Regulatory Integrative and Comparative Physiology 265, no. 5 34-5 (January 1, 1993).
  - Watkins, L., and W. Maixner. “The effect of pentobarbital anesthesia on the autonomic nervous system control of heart rate during baroreceptor activation.” J Auton Nerv Syst 36, no. 2 (November 1991): 107–14. https://doi.org/10.1016/0165-1838(91)90106-d.
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  - Sumners, C., L. L. Watkins, and M. K. Raizada. “Alpha 1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures.” J Neurochem 47, no. 4 (October 1986): 1117–26. https://doi.org/10.1111/j.1471-4159.1986.tb00729.x.
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  - Sumners, C., L. L. Watkins, and M. K. Raizada. “α₁-Adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures.” Journal of Neurochemistry 47, no. 4 (1986): 1117–26.
  - Rowland, N., L. Watkins, and J. Carlton. “Failure of 2-deoxy-D-glucose to stimulate feeding in deermice.” Physiol Behav 34, no. 1 (January 1985): 155–57. https://doi.org/10.1016/0031-9384(85)90095-2.
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- Book Sections
  - Lett, H. S., A. Sherwood, L. Watkins, and J. A. Blumenthal. “Depression and prognosis in cardiac patients.” In Depression and Physical Illness, 87–108, 2006. https://doi.org/10.1017/CBO9780511544293.005.
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